Explore - Molecular AOP Builder

KE ID	KE Title	GO ID	GO Name	Connection Type	Confidence Level	Proposer	Last updated	AOP context
KE 177	Increase, Mitochondrial dysfunction	GO:0140053	mitochondrial gene expression	describes	medium	SidraAdil	2026-05-10	AOP 130, AOP 144, AOP 178, AOP 200, AOP 205, AOP 207, AOP 256, AOP 258, AOP 273, AOP 3, AOP 335, AOP 34, AOP 362, AOP 377, AOP 423, AOP 437, AOP 447, AOP 464, AOP 476, AOP 479, AOP 48, AOP 480, AOP 481, AOP 497, AOP 500, AOP 509, AOP 511, AOP 530, AOP 587, AOP 588, AOP 589, AOP 595, AOP 622, AOP 624, AOP 625, AOP 626, AOP 77, AOP 78, AOP 79, AOP 80, AOP 87, AOP 472
KE 57	Proliferation, Cell proliferation in the absence of cytotoxicity	GO:0051301	cell division	describes	medium	SidraAdil	2026-05-10	AOP 1
KE 142	Hyperplasia, Hyperplasia	GO:0014738	regulation of muscle hyperplasia	describes	high	SidraAdil	2026-05-10	AOP 1
KE 334	Promotion, Hepatocelluar carcinoma	GO:2000345	regulation of hepatocyte proliferation	involves	medium	SidraAdil	2026-05-10	AOP 1
KE 214	Bile accumulation, Pathological condition	GO:0015721	bile acid and bile salt transport	describes	medium	SidraAdil	2026-05-10	AOP 27
KE 55	Increase, Cell injury/death	GO:0043525	positive regulation of neuron apoptotic process	describes	high	-	2026-02-23	AOP 12, AOP 13, AOP 144, AOP 17, AOP 264, AOP 265, AOP 266, AOP 268, AOP 273, AOP 278, AOP 281, AOP 324, AOP 331, AOP 377, AOP 38, AOP 479, AOP 48, AOP 490, AOP 494, AOP 530, AOP 596, AOP 599, AOP 624, AOP 625, AOP 626, AOP 627, AOP 628, AOP 629
KE 55	Increase, Cell injury/death	GO:0006915	apoptotic process	describes	medium	-	2026-02-07	AOP 12, AOP 13, AOP 144, AOP 17, AOP 264, AOP 265, AOP 266, AOP 268, AOP 273, AOP 278, AOP 281, AOP 324, AOP 331, AOP 377, AOP 38, AOP 479, AOP 48, AOP 490, AOP 494, AOP 530, AOP 596, AOP 599, AOP 624, AOP 625, AOP 626, AOP 627, AOP 628, AOP 629

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