Connecting Key Events to Molecular Pathways

A curated, FAIR database linking AOP Key Events to WikiPathways, Gene Ontology, and Reactome — enabling gene-set enrichment and mechanistic network analysis in toxicology.

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KE → WikiPathways
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KE → Gene Ontology
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KE → Reactome
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Total Mappings
WikiPathways: 2026-05-10 Reactome: v96 GO: 2026-01-23 AOP-Wiki: 2026-05-28
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How it works

  1. 1
    Pick a Key Event Browse AOP Key Events retrieved from the AOP-Wiki knowledge base.
  2. 2
    Review AI-ranked suggestions BioBERT semantic similarity ranks candidate WikiPathways, GO terms, and Reactome pathways.
  3. 3
    Propose a mapping Submit and justify your chosen connection — curators approve, and the mapping enters the FAIR database.