@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix ke-wp: <https://ke-wp-mapping.org/vocab#> .
@prefix mapping: <https://ke-wp-mapping.org/mapping/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

mapping:00c68fec-ca92-4eae-87af-e45f5d7fd129 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:13:58.705415"^^xsd:dateTime ;
    dcterms:identifier "00c68fec-ca92-4eae-87af-e45f5d7fd129" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 178" ;
    ke-wp:keyEventName "Mitochondrial electron transport chain, disrupted" ;
    ke-wp:pathwayId "WP111" ;
    ke-wp:pathwayTitle "Electron transport chain: OXPHOS system in mitochondria" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:0138f004-96d7-40ba-97c7-a1e74eb5cccb a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-09-25T13:19:49"^^xsd:dateTime ;
    dcterms:identifier "0138f004-96d7-40ba-97c7-a1e74eb5cccb" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 468" ;
    ke-wp:keyEventName "Inhibition, PPAR alpha" ;
    ke-wp:pathwayId "WP2878" ;
    ke-wp:pathwayTitle "PPAR-alpha pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:01e32369-e81d-487d-b083-6b7d2e2658f3 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:59:59.791602"^^xsd:dateTime ;
    dcterms:identifier "01e32369-e81d-487d-b083-6b7d2e2658f3" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 898" ;
    ke-wp:keyEventName "Disruption, Lysosome" ;
    ke-wp:pathwayId "WP4923" ;
    ke-wp:pathwayTitle "Autophagy" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:02aa0594-f1db-49cc-b940-afc5cb08a8bf a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:22.801171"^^xsd:dateTime ;
    dcterms:identifier "02aa0594-f1db-49cc-b940-afc5cb08a8bf" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1493" ;
    ke-wp:keyEventName "Increased Pro-inflammatory mediators" ;
    ke-wp:pathwayId "WP453" ;
    ke-wp:pathwayTitle "Inflammatory response pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:03b07f97-c4ff-4c38-8367-4e065237d661 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:59:54.384525"^^xsd:dateTime ;
    dcterms:identifier "03b07f97-c4ff-4c38-8367-4e065237d661" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 898" ;
    ke-wp:keyEventName "Disruption, Lysosome" ;
    ke-wp:pathwayId "WP183" ;
    ke-wp:pathwayTitle "Proteasome degradation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:04a53bdb-bfdb-4419-ae23-f5577a59e4d9 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:14:13.427613"^^xsd:dateTime ;
    dcterms:identifier "04a53bdb-bfdb-4419-ae23-f5577a59e4d9" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 40" ;
    ke-wp:keyEventName "Mitochondrial ATP production, decreased" ;
    ke-wp:pathwayId "WP5049" ;
    ke-wp:pathwayTitle "Glycolysis in senescence" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:04ac87f4-63bf-497a-b769-bf30ec13471d a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:15:29.509837"^^xsd:dateTime ;
    dcterms:identifier "04ac87f4-63bf-497a-b769-bf30ec13471d" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 122" ;
    ke-wp:keyEventName "Increase, Glucocorticoid receptor activation" ;
    ke-wp:pathwayId "WP2880" ;
    ke-wp:pathwayTitle "Glucocorticoid receptor pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:059a1c15-b17b-486a-9a3d-ebd7d2dc55c6 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:14:35.064635"^^xsd:dateTime ;
    dcterms:identifier "059a1c15-b17b-486a-9a3d-ebd7d2dc55c6" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 664" ;
    ke-wp:keyEventName "Overwhelmed, Mitochondrial DNA repair mechanisms" ;
    ke-wp:pathwayId "WP4946" ;
    ke-wp:pathwayTitle "DNA repair pathways, full network" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:06594da6-55e3-4478-af0e-0ecff614bdd8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:59.517518"^^xsd:dateTime ;
    dcterms:identifier "06594da6-55e3-4478-af0e-0ecff614bdd8" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 829" ;
    ke-wp:keyEventName "Damage, Lipid bilayer" ;
    ke-wp:pathwayId "WP5584" ;
    ke-wp:pathwayTitle "Signaling lipids" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:081fd464-efbf-4a29-8cc8-a250d30996b8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T08:48:52.213466"^^xsd:dateTime ;
    dcterms:identifier "081fd464-efbf-4a29-8cc8-a250d30996b8" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1392" ;
    ke-wp:keyEventName "Increase, Oxidative Stress" ;
    ke-wp:pathwayId "WP5477" ;
    ke-wp:pathwayTitle "Molecular pathway for oxidative stress" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:0b2bbce5-21b2-444c-9e0c-f83379970b36 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:14:26.847026"^^xsd:dateTime ;
    dcterms:identifier "0b2bbce5-21b2-444c-9e0c-f83379970b36" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1825" ;
    ke-wp:keyEventName "Increase, Cell death" ;
    ke-wp:pathwayId "WP4923" ;
    ke-wp:pathwayTitle "Autophagy" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:0b8e0188-4a6d-4808-a9a2-9b0d0177f741 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-07T19:40:47"^^xsd:dateTime ;
    dcterms:identifier "0b8e0188-4a6d-4808-a9a2-9b0d0177f741" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 889" ;
    ke-wp:keyEventName "Proteostasis, impaired" ;
    ke-wp:pathwayId "WP4918" ;
    ke-wp:pathwayTitle "Cellular proteostasis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:0bad2bc9-8022-4a21-943e-60bce8096e80 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:43.862998"^^xsd:dateTime ;
    dcterms:identifier "0bad2bc9-8022-4a21-943e-60bce8096e80" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 465" ;
    ke-wp:keyEventName "Increased, Fatty acid influx" ;
    ke-wp:pathwayId "WP5061" ;
    ke-wp:pathwayTitle "Fatty acid transporters" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:103f9312-a5db-4d28-b6f1-9c46cf1ac8e8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-10T11:13:32.167453"^^xsd:dateTime ;
    dcterms:identifier "103f9312-a5db-4d28-b6f1-9c46cf1ac8e8" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 474" ;
    ke-wp:keyEventName "Down Regulation, HMGCS2" ;
    ke-wp:pathwayId "WP4718" ;
    ke-wp:pathwayTitle "Cholesterol metabolism with Bloch and Kandutsch-Russell pathways" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:10ccb991-68a7-49c9-be6c-03adedde9256 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:06.207950"^^xsd:dateTime ;
    dcterms:identifier "10ccb991-68a7-49c9-be6c-03adedde9256" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 837" ;
    ke-wp:keyEventName "Occurrence, Cytoplasmic vacuolization (kupffer cell)" ;
    ke-wp:pathwayId "WP3965" ;
    ke-wp:pathwayTitle "Lipid metabolism pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:11d306d0-8f83-44e2-a514-afdeb998e65f a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-25T09:45:55"^^xsd:dateTime ;
    dcterms:identifier "11d306d0-8f83-44e2-a514-afdeb998e65f" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 87" ;
    ke-wp:keyEventName "Release, Cytokine" ;
    ke-wp:pathwayId "WP530" ;
    ke-wp:pathwayTitle "Cytokines and inflammatory response" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:142fe8a3-2cd0-48d1-98b9-c3f891a2e0b8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T09:38:28.259004"^^xsd:dateTime ;
    dcterms:identifier "142fe8a3-2cd0-48d1-98b9-c3f891a2e0b8" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1365" ;
    ke-wp:keyEventName "Increase, Apoptosis" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:14929bcf-8df9-4685-a372-f941487abf37 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:09:18.273157"^^xsd:dateTime ;
    dcterms:identifier "14929bcf-8df9-4685-a372-f941487abf37" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1195" ;
    ke-wp:keyEventName "modulation, Extracellular Matrix Composition" ;
    ke-wp:pathwayId "WP5382" ;
    ke-wp:pathwayTitle "TGFB / Smad signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:16445bb4-4543-4cbf-bb87-46cd02c3aedb a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:59:47.408042"^^xsd:dateTime ;
    dcterms:identifier "16445bb4-4543-4cbf-bb87-46cd02c3aedb" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1539" ;
    ke-wp:keyEventName "Endocytotic lysosomal uptake" ;
    ke-wp:pathwayId "WP4655" ;
    ke-wp:pathwayTitle "Cytosolic DNA-sensing pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:1bb5d670-625b-4695-8d00-ceccdcb0bd91 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:28.797927"^^xsd:dateTime ;
    dcterms:identifier "1bb5d670-625b-4695-8d00-ceccdcb0bd91" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 2406" ;
    ke-wp:keyEventName "Increase, Regenerative nodule formation" ;
    ke-wp:pathwayId "WP3932" ;
    ke-wp:pathwayTitle "Focal adhesion: PI3K-Akt-mTOR-signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:21deba79-e0c2-4a01-beb0-7680d85e964f a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-10T11:13:43.598526"^^xsd:dateTime ;
    dcterms:identifier "21deba79-e0c2-4a01-beb0-7680d85e964f" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 115" ;
    ke-wp:keyEventName "Increase, FA Influx" ;
    ke-wp:pathwayId "WP5061" ;
    ke-wp:pathwayTitle "Fatty acid transporters" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:21f40e2d-5f36-4336-a62e-dc2dafdef26a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-23T10:06:21.147901"^^xsd:dateTime ;
    dcterms:identifier "21f40e2d-5f36-4336-a62e-dc2dafdef26a" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 227" ;
    ke-wp:keyEventName "Activation, PPARα" ;
    ke-wp:pathwayId "WP2878" ;
    ke-wp:pathwayTitle "PPAR-alpha pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:21f99235-bf4a-4046-b775-bb98b368157d a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:58:26.778742"^^xsd:dateTime ;
    dcterms:identifier "21f99235-bf4a-4046-b775-bb98b368157d" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 459" ;
    ke-wp:keyEventName "Increased, Liver Steatosis" ;
    ke-wp:pathwayId "WP3965" ;
    ke-wp:pathwayTitle "Lipid metabolism pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:27373650-58e1-4f1a-aaba-c75f4ecf9fdb a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:21.759903"^^xsd:dateTime ;
    dcterms:identifier "27373650-58e1-4f1a-aaba-c75f4ecf9fdb" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 105" ;
    ke-wp:keyEventName "Inhibition, Mitochondrial Electron Transport Chain Complexes" ;
    ke-wp:pathwayId "WP111" ;
    ke-wp:pathwayTitle "Electron transport chain: OXPHOS system in mitochondria" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:2762aab1-afb2-4492-a3f2-6111c21fb8d7 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T06:05:59"^^xsd:dateTime ;
    dcterms:identifier "2762aab1-afb2-4492-a3f2-6111c21fb8d7" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 25" ;
    ke-wp:keyEventName "KE 25 - Agonism, Androgen receptor" ;
    ke-wp:pathwayId "WP272" ;
    ke-wp:pathwayTitle "Blood clotting cascade" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:2b0b07b3-78a7-4845-a30d-ee5d15ff8439 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T06:07:52"^^xsd:dateTime ;
    dcterms:identifier "2b0b07b3-78a7-4845-a30d-ee5d15ff8439" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 345" ;
    ke-wp:keyEventName "KE 345 - N/A, Liver Steatosis" ;
    ke-wp:pathwayId "WP4010" ;
    ke-wp:pathwayTitle "Liver steatosis adverse outcome pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:2c6fac33-0002-407a-99e6-2bfc17bd24c4 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:39.435051"^^xsd:dateTime ;
    dcterms:identifier "2c6fac33-0002-407a-99e6-2bfc17bd24c4" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 2408" ;
    ke-wp:keyEventName "Increase, Adipose lipolysis" ;
    ke-wp:pathwayId "WP236" ;
    ke-wp:pathwayTitle "Adipogenesis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:30c7ed6a-6344-4d87-9792-467ed95646db a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "guest-test-participant" ;
    dcterms:date "2026-02-17T21:09:14"^^xsd:dateTime ;
    dcterms:identifier "30c7ed6a-6344-4d87-9792-467ed95646db" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "low" ;
    ke-wp:keyEventId "KE 123" ;
    ke-wp:keyEventName "Test Key Event" ;
    ke-wp:pathwayId "WP1234" ;
    ke-wp:pathwayTitle "Test Pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:342f57b2-6a1b-4163-8e72-afbfbebf3e2a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-04T15:40:06.892136"^^xsd:dateTime ;
    dcterms:identifier "342f57b2-6a1b-4163-8e72-afbfbebf3e2a" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 55" ;
    ke-wp:keyEventName "Increase, Cell injury/death" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:376fba0c-4479-4239-9935-c76484eb12cd a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:58:05.530964"^^xsd:dateTime ;
    dcterms:identifier "376fba0c-4479-4239-9935-c76484eb12cd" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 18" ;
    ke-wp:keyEventName "Activation, AhR" ;
    ke-wp:pathwayId "WP2873" ;
    ke-wp:pathwayTitle "Aryl hydrocarbon receptor pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:3800a94e-acc6-4463-a8d3-d508911cc4e6 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:38:49.861003"^^xsd:dateTime ;
    dcterms:identifier "3800a94e-acc6-4463-a8d3-d508911cc4e6" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 833" ;
    ke-wp:keyEventName "Occurrence, Cytoplasmic vacuolization (hepatocyte)" ;
    ke-wp:pathwayId "WP3965" ;
    ke-wp:pathwayTitle "Lipid metabolism pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:38705c21-ae84-4678-b59e-e6405de3b187 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-14T06:51:54"^^xsd:dateTime ;
    dcterms:identifier "38705c21-ae84-4678-b59e-e6405de3b187" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 28" ;
    ke-wp:keyEventName "Reduction, Angiogenesis" ;
    ke-wp:pathwayId "WP1539" ;
    ke-wp:pathwayTitle "Angiogenesis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:39928d1c-c27c-46e4-baa4-1eaa957848e3 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T17:00:18.159156"^^xsd:dateTime ;
    dcterms:identifier "39928d1c-c27c-46e4-baa4-1eaa957848e3" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 265" ;
    ke-wp:keyEventName "Activation, Stellate cells" ;
    ke-wp:pathwayId "WP560" ;
    ke-wp:pathwayTitle "TGF-beta receptor signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:3acb794f-7ca9-43ea-a33d-6523007b0534 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:09:14.731814"^^xsd:dateTime ;
    dcterms:identifier "3acb794f-7ca9-43ea-a33d-6523007b0534" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1395" ;
    ke-wp:keyEventName "Liver Cancer" ;
    ke-wp:pathwayId "WP3646" ;
    ke-wp:pathwayTitle "Hepatitis C and hepatocellular carcinoma" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:3bd9947e-f807-4d55-9b52-02b9c756b187 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
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    dcterms:identifier "3bd9947e-f807-4d55-9b52-02b9c756b187" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1115" ;
    ke-wp:keyEventName "Increase, Reactive oxygen species" ;
    ke-wp:pathwayId "WP5477" ;
    ke-wp:pathwayTitle "Molecular pathway for oxidative stress" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:3cbd2aee-253f-4c71-baed-dae19f96ddb2 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T11:59:00.133709"^^xsd:dateTime ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1194" ;
    ke-wp:keyEventName "Increase, DNA damage" ;
    ke-wp:pathwayId "WP707" ;
    ke-wp:pathwayTitle "DNA damage response" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:40838948-42b5-49ce-acef-8bd45cd08ff6 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:38:43.255042"^^xsd:dateTime ;
    dcterms:identifier "40838948-42b5-49ce-acef-8bd45cd08ff6" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1262" ;
    ke-wp:keyEventName "Apoptosis" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:40b9cce4-e978-4516-9312-8e0766eb745c a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:17.416054"^^xsd:dateTime ;
    dcterms:identifier "40b9cce4-e978-4516-9312-8e0766eb745c" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1105" ;
    ke-wp:keyEventName "Occurrence, renal ischemia" ;
    ke-wp:pathwayId "WP4298" ;
    ke-wp:pathwayTitle "Acute viral myocarditis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:413c7311-b688-4f3c-ae3a-b1df32a18fc7 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-10-21T06:41:17"^^xsd:dateTime ;
    dcterms:identifier "413c7311-b688-4f3c-ae3a-b1df32a18fc7" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 111" ;
    ke-wp:keyEventName "Agonism, Estrogen receptor" ;
    ke-wp:pathwayId "WP2881" ;
    ke-wp:pathwayTitle "Estrogen receptor pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:427e6bb4-caa2-450d-ba19-4ea90c85907d a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:22.099238"^^xsd:dateTime ;
    dcterms:identifier "427e6bb4-caa2-450d-ba19-4ea90c85907d" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1815" ;
    ke-wp:keyEventName "Increase, Endoplasmic reticulum stress" ;
    ke-wp:pathwayId "WP4925" ;
    ke-wp:pathwayTitle "Unfolded protein response" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:42d1c812-5b76-4a3f-88a7-d486368625d4 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-10-01T16:57:43"^^xsd:dateTime ;
    dcterms:identifier "42d1c812-5b76-4a3f-88a7-d486368625d4" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 12" ;
    ke-wp:keyEventName "Acetylcholinesterase (AchE) Inhibition" ;
    ke-wp:pathwayId "WP1602" ;
    ke-wp:pathwayTitle "Nicotine effect on dopaminergic neurons" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:4328b6f0-edc4-4d5a-ad46-3e5316b303ad a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T17:00:45.616529"^^xsd:dateTime ;
    dcterms:identifier "4328b6f0-edc4-4d5a-ad46-3e5316b303ad" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1493" ;
    ke-wp:keyEventName "Increased Pro-inflammatory mediators" ;
    ke-wp:pathwayId "WP530" ;
    ke-wp:pathwayTitle "Cytokines and inflammatory response" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:45008303-2c25-4ada-8068-744793322926 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:16.453079"^^xsd:dateTime ;
    dcterms:identifier "45008303-2c25-4ada-8068-744793322926" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 831" ;
    ke-wp:keyEventName "Disturbance, Lysosomal function" ;
    ke-wp:pathwayId "WP183" ;
    ke-wp:pathwayTitle "Proteasome degradation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:467a0fbc-a4fa-4653-a1b7-2c99f94f18f2 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:14.239277"^^xsd:dateTime ;
    dcterms:identifier "467a0fbc-a4fa-4653-a1b7-2c99f94f18f2" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1395" ;
    ke-wp:keyEventName "Liver Cancer" ;
    ke-wp:pathwayId "WP5434" ;
    ke-wp:pathwayTitle "Cancer pathways" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:468515f6-3799-43c3-9cc4-2892ed266990 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:14:55.641134"^^xsd:dateTime ;
    dcterms:identifier "468515f6-3799-43c3-9cc4-2892ed266990" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 40" ;
    ke-wp:keyEventName "Mitochondrial ATP production, decreased" ;
    ke-wp:pathwayId "WP5241" ;
    ke-wp:pathwayTitle "Mitochondrial beta-oxidation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:4ac6be90-26fe-4789-a7fc-bf1a67ee53fd a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:58:47.951073"^^xsd:dateTime ;
    dcterms:identifier "4ac6be90-26fe-4789-a7fc-bf1a67ee53fd" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1740" ;
    ke-wp:keyEventName "Induced dysregulation of ACE2" ;
    ke-wp:pathwayId "WP554" ;
    ke-wp:pathwayTitle "ACE inhibitor pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:4bc9372a-3b46-4fe9-82d3-685e3c05620b a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:08.715823"^^xsd:dateTime ;
    dcterms:identifier "4bc9372a-3b46-4fe9-82d3-685e3c05620b" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 177" ;
    ke-wp:keyEventName "Increase, Mitochondrial dysfunction" ;
    ke-wp:pathwayId "WP5507" ;
    ke-wp:pathwayTitle "Mitochondrial carrier deficiency associated with shuttle disturbances" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:4f329e87-3247-4a73-90c2-bae7f78a9350 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:09:02.741594"^^xsd:dateTime ;
    dcterms:identifier "4f329e87-3247-4a73-90c2-bae7f78a9350" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 840" ;
    ke-wp:keyEventName "Formation, Liver fibrosis" ;
    ke-wp:pathwayId "WP3980" ;
    ke-wp:pathwayTitle "Protein alkylation leading to liver fibrosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:4f78f4fb-e5db-43ae-84dc-29ac03b27c14 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:18.788438"^^xsd:dateTime ;
    dcterms:identifier "4f78f4fb-e5db-43ae-84dc-29ac03b27c14" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1306" ;
    ke-wp:keyEventName "Increase, De novo lipogenesis" ;
    ke-wp:pathwayId "WP3965" ;
    ke-wp:pathwayTitle "Lipid metabolism pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:535d741b-8f8c-4201-ae06-ea6cd06bdafa a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 269" ;
    ke-wp:keyEventName "Induction, Sustained Cell Proliferation" ;
    ke-wp:pathwayId "WP5475" ;
    ke-wp:pathwayTitle "Hallmark of cancer: sustaining proliferative signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:58a8c278-8efe-4f81-bf80-1fae402460ce a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:15.125934"^^xsd:dateTime ;
    dcterms:identifier "58a8c278-8efe-4f81-bf80-1fae402460ce" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 819" ;
    ke-wp:keyEventName "Decreased, Glomerular filtration" ;
    ke-wp:pathwayId "WP2572" ;
    ke-wp:pathwayTitle "Primary focal segmental glomerulosclerosis (FSGS)" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:5cf9cbb2-55ee-4cc8-a14c-04ee235275dd a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:56.142557"^^xsd:dateTime ;
    dcterms:identifier "5cf9cbb2-55ee-4cc8-a14c-04ee235275dd" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 344" ;
    ke-wp:keyEventName "N/A, Liver fibrosis" ;
    ke-wp:pathwayId "WP3980" ;
    ke-wp:pathwayTitle "Protein alkylation leading to liver fibrosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:618c2abc-12a9-4091-ade3-4376740f7836 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:58:56.163068"^^xsd:dateTime ;
    dcterms:identifier "618c2abc-12a9-4091-ade3-4376740f7836" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1743" ;
    ke-wp:keyEventName "Increase plasma Ang II" ;
    ke-wp:pathwayId "WP4756" ;
    ke-wp:pathwayTitle "Renin-angiotensin-aldosterone system (RAAS)" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:66ff7c41-d4c0-4555-8ac2-6e96f8941d6d a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:25.346790"^^xsd:dateTime ;
    dcterms:identifier "66ff7c41-d4c0-4555-8ac2-6e96f8941d6d" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 2412" ;
    ke-wp:keyEventName "Increase, Hepatic intracellular active glucocorticoids" ;
    ke-wp:pathwayId "WP5280" ;
    ke-wp:pathwayTitle "Glucocorticoid biosynthesis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:67cd49e4-bea7-4471-bf83-b693457e821a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:10.414920"^^xsd:dateTime ;
    dcterms:identifier "67cd49e4-bea7-4471-bf83-b693457e821a" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 838" ;
    ke-wp:keyEventName "Induction, Microvesicular fat" ;
    ke-wp:pathwayId "WP4149" ;
    ke-wp:pathwayTitle "White fat cell differentiation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:6bb30d07-942e-45e0-a8be-113b8c4a1ee7 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-11T18:32:08.534730"^^xsd:dateTime ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 177" ;
    ke-wp:keyEventName "Increase, Mitochondrial dysfunction" ;
    ke-wp:pathwayId "WP78" ;
    ke-wp:pathwayTitle "TCA cycle (aka Krebs or citric acid cycle)" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:6c09bce6-b0a3-4eec-9a3c-cdc29e340a27 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-11T18:16:47.739924"^^xsd:dateTime ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1825" ;
    ke-wp:keyEventName "Increase, Cell death" ;
    ke-wp:pathwayId "WP1772" ;
    ke-wp:pathwayTitle "Apoptosis modulation and signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:6d02cf1e-9d5d-4ff9-b653-11a8062d33b7 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 836" ;
    ke-wp:keyEventName "Occurrence, Cytoplasmic vacuolization (Bile duct cell)" ;
    ke-wp:pathwayId "WP3965" ;
    ke-wp:pathwayTitle "Lipid metabolism pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:742b5962-500e-405b-ac14-240b7a6f666e a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 188" ;
    ke-wp:keyEventName "Neuroinflammation" ;
    ke-wp:pathwayId "WP4919" ;
    ke-wp:pathwayTitle "Neuroinflammation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:75add0dc-cf87-4893-9204-3a49cbd0a961 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 2407" ;
    ke-wp:keyEventName "Increase, Cirrhosis" ;
    ke-wp:pathwayId "WP5382" ;
    ke-wp:pathwayTitle "TGFB / Smad signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:772e8aa1-85ff-41ba-a3da-ce139f3adc5b a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1392" ;
    ke-wp:keyEventName "Oxidative Stress" ;
    ke-wp:pathwayId "WP408" ;
    ke-wp:pathwayTitle "Oxidative stress response" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:79ad02a0-a157-4746-aa8d-070f4db8240e a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T05:42:58"^^xsd:dateTime ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 25" ;
    ke-wp:keyEventName "KE 25 - Agonism, Androgen receptor" ;
    ke-wp:pathwayId "WP138" ;
    ke-wp:pathwayTitle "Androgen receptor signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:85f40708-4bce-4160-9235-b4ff5ab0fb06 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
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    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1492" ;
    ke-wp:keyEventName "Tissue resident cell activation" ;
    ke-wp:pathwayId "WP560" ;
    ke-wp:pathwayTitle "TGF-beta receptor signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:8aba0b0c-1d85-4ba8-8dab-dc1bd303b33a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-24T13:29:57.881637"^^xsd:dateTime ;
    dcterms:identifier "8aba0b0c-1d85-4ba8-8dab-dc1bd303b33a" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1283" ;
    ke-wp:keyEventName "Activation, TGF-beta pathway" ;
    ke-wp:pathwayId "WP560" ;
    ke-wp:pathwayTitle "TGF-beta receptor signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:8c6b2d57-e547-4573-9f3b-5aa50585b635 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:38:30.437906"^^xsd:dateTime ;
    dcterms:identifier "8c6b2d57-e547-4573-9f3b-5aa50585b635" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 870" ;
    ke-wp:keyEventName "Increase, Cell Proliferation" ;
    ke-wp:pathwayId "WP179" ;
    ke-wp:pathwayTitle "Cell cycle" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:8e02b782-6c64-4874-afb7-0b955c6f3b53 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:38:54.089966"^^xsd:dateTime ;
    dcterms:identifier "8e02b782-6c64-4874-afb7-0b955c6f3b53" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 831" ;
    ke-wp:keyEventName "Disturbance, Lysosomal function" ;
    ke-wp:pathwayId "WP4923" ;
    ke-wp:pathwayTitle "Autophagy" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:90896f40-d1ea-4eb4-b1b6-fcebc7d06617 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:33.341949"^^xsd:dateTime ;
    dcterms:identifier "90896f40-d1ea-4eb4-b1b6-fcebc7d06617" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 828" ;
    ke-wp:keyEventName "Inhibition, Phospholipase A" ;
    ke-wp:pathwayId "WP3965" ;
    ke-wp:pathwayTitle "Lipid metabolism pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:91163daf-9bd8-48d5-b01e-4d958ee01496 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T17:00:06.435968"^^xsd:dateTime ;
    dcterms:identifier "91163daf-9bd8-48d5-b01e-4d958ee01496" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 68" ;
    ke-wp:keyEventName "Accumulation, Collagen" ;
    ke-wp:pathwayId "WP560" ;
    ke-wp:pathwayTitle "TGF-beta receptor signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:935eb43f-3226-4cf1-abce-d38cbe9f91c2 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T08:48:57.442432"^^xsd:dateTime ;
    dcterms:identifier "935eb43f-3226-4cf1-abce-d38cbe9f91c2" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 177" ;
    ke-wp:keyEventName "Increase, Mitochondrial dysfunction" ;
    ke-wp:pathwayId "WP623" ;
    ke-wp:pathwayTitle "Oxidative phosphorylation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:93fce828-81cd-4305-b7ba-1b36ca0650f5 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:30.831620"^^xsd:dateTime ;
    dcterms:identifier "93fce828-81cd-4305-b7ba-1b36ca0650f5" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 926" ;
    ke-wp:keyEventName "Oxidation, Glutathione (To be considered with MIE)" ;
    ke-wp:pathwayId "WP100" ;
    ke-wp:pathwayTitle "Glutathione metabolism" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:94bdac0c-dbd6-4680-b6ed-f52a9fccad74 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T17:00:26.988024"^^xsd:dateTime ;
    dcterms:identifier "94bdac0c-dbd6-4680-b6ed-f52a9fccad74" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1494" ;
    ke-wp:keyEventName "Leukocyte recruitment/activation" ;
    ke-wp:pathwayId "WP4542" ;
    ke-wp:pathwayTitle "Leukocyte-intrinsic Hippo pathway functions" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:97e56fdd-c416-46a5-86bd-02df2ef90cc9 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:40:09.684399"^^xsd:dateTime ;
    dcterms:identifier "97e56fdd-c416-46a5-86bd-02df2ef90cc9" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 839" ;
    ke-wp:keyEventName "Formation, Mallory body" ;
    ke-wp:pathwayId "WP183" ;
    ke-wp:pathwayTitle "Proteasome degradation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:9e3bc5f4-7243-41fd-afd6-f70cf049e801 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:58:20.827052"^^xsd:dateTime ;
    dcterms:identifier "9e3bc5f4-7243-41fd-afd6-f70cf049e801" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1489" ;
    ke-wp:keyEventName "N/A, Steatohepatisis" ;
    ke-wp:pathwayId "WP453" ;
    ke-wp:pathwayTitle "Inflammatory response pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:9e6f4b97-1fea-4db3-b6e0-4abd4f060cc4 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:38:39.272632"^^xsd:dateTime ;
    dcterms:identifier "9e6f4b97-1fea-4db3-b6e0-4abd4f060cc4" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1967" ;
    ke-wp:keyEventName "Pyroptosis" ;
    ke-wp:pathwayId "WP453" ;
    ke-wp:pathwayTitle "Inflammatory response pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:9f064b32-a4ab-4c50-8f64-4db70aea6f7b a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-01-13T13:14:59"^^xsd:dateTime ;
    dcterms:identifier "9f064b32-a4ab-4c50-8f64-4db70aea6f7b" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 55" ;
    ke-wp:keyEventName "Increase, Cell injury/death" ;
    ke-wp:pathwayId "WP2507" ;
    ke-wp:pathwayTitle "Nanomaterial induced apoptosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:a24e3558-b5e3-4f87-ad93-f123cf34c8bb a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:09:25.582533"^^xsd:dateTime ;
    dcterms:identifier "a24e3558-b5e3-4f87-ad93-f123cf34c8bb" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1096" ;
    ke-wp:keyEventName "Increased, blood uric acid concentration" ;
    ke-wp:pathwayId "WP4595" ;
    ke-wp:pathwayTitle "Urea cycle and associated pathways" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:a28dd624-1171-4780-bc8c-1c17fd83004d a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:42.802911"^^xsd:dateTime ;
    dcterms:identifier "a28dd624-1171-4780-bc8c-1c17fd83004d" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 2405" ;
    ke-wp:keyEventName "Increase, Hepatocellular lipotoxicity" ;
    ke-wp:pathwayId "WP5323" ;
    ke-wp:pathwayTitle "Fatty acid and lipoprotein transport in hepatocytes" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:a47b791d-61c4-4f9e-9db4-92e49c230ee4 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:08:51.097651"^^xsd:dateTime ;
    dcterms:identifier "a47b791d-61c4-4f9e-9db4-92e49c230ee4" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 839" ;
    ke-wp:keyEventName "Formation, Mallory body" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:a5c102fa-7b60-48fa-90e3-b7b811e583af a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T11:59:09.512244"^^xsd:dateTime ;
    dcterms:identifier "a5c102fa-7b60-48fa-90e3-b7b811e583af" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1825" ;
    ke-wp:keyEventName "Increase, Cell death" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:a6638a2b-0e38-4d4f-9e09-89b36b530398 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:33.602913"^^xsd:dateTime ;
    dcterms:identifier "a6638a2b-0e38-4d4f-9e09-89b36b530398" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 40" ;
    ke-wp:keyEventName "Mitochondrial ATP production, decreased" ;
    ke-wp:pathwayId "WP391" ;
    ke-wp:pathwayTitle "Mitochondrial gene expression" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:a729c940-c492-4161-a76f-eab6af7d8ce1 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:58:42.977046"^^xsd:dateTime ;
    dcterms:identifier "a729c940-c492-4161-a76f-eab6af7d8ce1" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1852" ;
    ke-wp:keyEventName "Increased Ang II type 1 receptor (AT1R)" ;
    ke-wp:pathwayId "WP5036" ;
    ke-wp:pathwayTitle "Angiotensin II receptor type 1 pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:a7c2e4cc-ef2d-4c74-8e4a-3b4dc8a3aa2a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:13.399987"^^xsd:dateTime ;
    dcterms:identifier "a7c2e4cc-ef2d-4c74-8e4a-3b4dc8a3aa2a" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 50" ;
    ke-wp:keyEventName "Increase, Ca++ (intracellular)" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:a7f286e7-0afc-49f9-8cc0-50c6c18a0f20 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:40:05.470862"^^xsd:dateTime ;
    dcterms:identifier "a7f286e7-0afc-49f9-8cc0-50c6c18a0f20" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 134" ;
    ke-wp:keyEventName "Increase, Kupffer cell activation" ;
    ke-wp:pathwayId "WP530" ;
    ke-wp:pathwayTitle "Cytokines and inflammatory response" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:adf9941e-23d8-45c9-8044-7fa2a5b7d40c a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-10T11:13:37.747859"^^xsd:dateTime ;
    dcterms:identifier "adf9941e-23d8-45c9-8044-7fa2a5b7d40c" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 471" ;
    ke-wp:keyEventName "Inhibition, FoxA2" ;
    ke-wp:pathwayId "WP5066" ;
    ke-wp:pathwayTitle "FOXA2 pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:affc3bd7-b0e5-4e1c-b94e-927a45f0d5b4 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:58:52.473186"^^xsd:dateTime ;
    dcterms:identifier "affc3bd7-b0e5-4e1c-b94e-927a45f0d5b4" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 459" ;
    ke-wp:keyEventName "Increased, Liver Steatosis" ;
    ke-wp:pathwayId "WP143" ;
    ke-wp:pathwayTitle "Fatty acid beta-oxidation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:b02b5b42-cbde-4ced-8bd1-a798861b4260 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:59:13.146695"^^xsd:dateTime ;
    dcterms:identifier "b02b5b42-cbde-4ced-8bd1-a798861b4260" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1501" ;
    ke-wp:keyEventName "Increased, extracellular matrix deposition" ;
    ke-wp:pathwayId "WP428" ;
    ke-wp:pathwayTitle "Wnt signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:b21ac548-dd63-480b-9199-7f9391587af8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T11:59:13.592007"^^xsd:dateTime ;
    dcterms:identifier "b21ac548-dd63-480b-9199-7f9391587af8" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 149" ;
    ke-wp:keyEventName "Increase, Inflammation" ;
    ke-wp:pathwayId "WP530" ;
    ke-wp:pathwayTitle "Cytokines and inflammatory response" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:b3b9ddea-5cfa-4bc5-a8f7-8e74755e2675 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:15:20.365434"^^xsd:dateTime ;
    dcterms:identifier "b3b9ddea-5cfa-4bc5-a8f7-8e74755e2675" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 459" ;
    ke-wp:keyEventName "Increase, Liver steatosis" ;
    ke-wp:pathwayId "WP4010" ;
    ke-wp:pathwayTitle "Liver steatosis adverse outcome pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:b411eceb-1489-47b9-8d06-6ea04a5dd5eb a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:38.805596"^^xsd:dateTime ;
    dcterms:identifier "b411eceb-1489-47b9-8d06-6ea04a5dd5eb" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 2406" ;
    ke-wp:keyEventName "Increase, Regenerative nodule formation" ;
    ke-wp:pathwayId "WP428" ;
    ke-wp:pathwayTitle "Wnt signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:b53d61ea-d3d8-45ea-b44c-309247dc7d28 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T05:47:13"^^xsd:dateTime ;
    dcterms:identifier "b53d61ea-d3d8-45ea-b44c-309247dc7d28" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 17" ;
    ke-wp:keyEventName "KE 17 - Altered gene expression, AHR nuclear translocator (ARNT)-dependent pathway" ;
    ke-wp:pathwayId "WP2882" ;
    ke-wp:pathwayTitle "Nuclear receptors meta-pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:b66987de-ae63-418e-a2a2-1d7562174851 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:51.610626"^^xsd:dateTime ;
    dcterms:identifier "b66987de-ae63-418e-a2a2-1d7562174851" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 9" ;
    ke-wp:keyEventName "Activation, 5HT2c" ;
    ke-wp:pathwayId "WP5239" ;
    ke-wp:pathwayTitle "Lac-Phe pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:b684145d-c10c-45cd-bcd2-d92eb80479e3 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:38:58.096891"^^xsd:dateTime ;
    dcterms:identifier "b684145d-c10c-45cd-bcd2-d92eb80479e3" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 835" ;
    ke-wp:keyEventName "Occurrence, Ballooning degeneration (hepatocyte)" ;
    ke-wp:pathwayId "WP4925" ;
    ke-wp:pathwayTitle "Unfolded protein response" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:b8eeaa97-12cc-466d-b735-2fdfb03d3e22 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T05:42:58"^^xsd:dateTime ;
    dcterms:identifier "b8eeaa97-12cc-466d-b735-2fdfb03d3e22" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 25" ;
    ke-wp:keyEventName "KE 25 - Agonism, Androgen receptor" ;
    ke-wp:pathwayId "WP2263" ;
    ke-wp:pathwayTitle "Androgen receptor network in prostate cancer" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:bb7b4563-1c93-4822-a3dc-3f77b1f509e1 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:38.622413"^^xsd:dateTime ;
    dcterms:identifier "bb7b4563-1c93-4822-a3dc-3f77b1f509e1" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1104" ;
    ke-wp:keyEventName "Decreased, Prostaglandin F2alpha concentration, plasma" ;
    ke-wp:pathwayId "WP98" ;
    ke-wp:pathwayTitle "Prostaglandin synthesis and regulation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:bbc8a46d-3b48-4b72-8845-a1fab1e4cc3a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T06:18:18"^^xsd:dateTime ;
    dcterms:identifier "bbc8a46d-3b48-4b72-8845-a1fab1e4cc3a" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 2336" ;
    ke-wp:keyEventName "Increase, SREBF1" ;
    ke-wp:pathwayId "WP22" ;
    ke-wp:pathwayTitle "IL9 signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:bc215442-82fc-4c24-8af1-6aa69e21e85a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:09:21.952584"^^xsd:dateTime ;
    dcterms:identifier "bc215442-82fc-4c24-8af1-6aa69e21e85a" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1306" ;
    ke-wp:keyEventName "Increase, De novo lipogenesis" ;
    ke-wp:pathwayId "WP236" ;
    ke-wp:pathwayTitle "Adipogenesis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:c002a994-b638-4c79-bbf7-76a578f527a0 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T06:13:34"^^xsd:dateTime ;
    dcterms:identifier "c002a994-b638-4c79-bbf7-76a578f527a0" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 2072" ;
    ke-wp:keyEventName "Increase, Mitochondrial swelling" ;
    ke-wp:pathwayId "WP5241" ;
    ke-wp:pathwayTitle "Mitochondrial beta-oxidation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:c11425fd-d781-4f36-815d-d8931a5d5c8c a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-10-02T11:08:38"^^xsd:dateTime ;
    dcterms:identifier "c11425fd-d781-4f36-815d-d8931a5d5c8c" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 10" ;
    ke-wp:keyEventName "Acetylcholine accumulation in synapses" ;
    ke-wp:pathwayId "WP528" ;
    ke-wp:pathwayTitle "Acetylcholine synthesis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:c2c192fb-179d-4e1a-b36e-938c134a6cd2 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:59:22.777421"^^xsd:dateTime ;
    dcterms:identifier "c2c192fb-179d-4e1a-b36e-938c134a6cd2" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1501" ;
    ke-wp:keyEventName "Increased, extracellular matrix deposition" ;
    ke-wp:pathwayId "WP560" ;
    ke-wp:pathwayTitle "TGF-beta receptor signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:c843f1b7-61d2-4ee6-9e1a-eea2631c6012 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:09:11.297665"^^xsd:dateTime ;
    dcterms:identifier "c843f1b7-61d2-4ee6-9e1a-eea2631c6012" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "low" ;
    ke-wp:keyEventId "KE 2410" ;
    ke-wp:keyEventName "Increase, 11β-Hydroxysteroid dehydrogenase type 1 activity" ;
    ke-wp:pathwayId "WP2880" ;
    ke-wp:pathwayTitle "Glucocorticoid receptor pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:ced7c569-aea1-4a72-b06b-223957a874d9 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:09:06.437923"^^xsd:dateTime ;
    dcterms:identifier "ced7c569-aea1-4a72-b06b-223957a874d9" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 149" ;
    ke-wp:keyEventName "Increase, Inflammation" ;
    ke-wp:pathwayId "WP453" ;
    ke-wp:pathwayTitle "Inflammatory response pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:d03eb198-e060-4046-9349-038d809dcaea a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-10-01T16:38:58"^^xsd:dateTime ;
    dcterms:identifier "d03eb198-e060-4046-9349-038d809dcaea" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 79" ;
    ke-wp:keyEventName "Inhibition, Cyclooxygenase activity" ;
    ke-wp:pathwayId "WP4719" ;
    ke-wp:pathwayTitle "Eicosanoid metabolism via cyclooxygenases (COX)" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:d16cb071-1f02-4089-989b-939c1391612e a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T05:47:13"^^xsd:dateTime ;
    dcterms:identifier "d16cb071-1f02-4089-989b-939c1391612e" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 17" ;
    ke-wp:keyEventName "KE 17 - Altered gene expression, AHR nuclear translocator (ARNT)-dependent pathway" ;
    ke-wp:pathwayId "WP2289" ;
    ke-wp:pathwayTitle "Drug induction of bile acid pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:d6d3f689-00ab-4f9a-8c49-e3a1e35a1547 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T08:48:33.834124"^^xsd:dateTime ;
    dcterms:identifier "d6d3f689-00ab-4f9a-8c49-e3a1e35a1547" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 281" ;
    ke-wp:keyEventName "Thyroxine (T4) in serum, Decreased" ;
    ke-wp:pathwayId "WP1981" ;
    ke-wp:pathwayTitle "Thyroxine (thyroid hormone) production" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:d7e879d1-c79f-4fc0-b6c8-6421d3a4a4fc a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:59:30.158836"^^xsd:dateTime ;
    dcterms:identifier "d7e879d1-c79f-4fc0-b6c8-6421d3a4a4fc" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 244" ;
    ke-wp:keyEventName "Alkylation, Protein" ;
    ke-wp:pathwayId "WP3980" ;
    ke-wp:pathwayTitle "Protein alkylation leading to liver fibrosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:db828dc6-9737-4e63-ba87-c6d45ad4ae8d a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:07.474042"^^xsd:dateTime ;
    dcterms:identifier "db828dc6-9737-4e63-ba87-c6d45ad4ae8d" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 709" ;
    ke-wp:keyEventName "Increase, Cytotoxicity (renal tubular cell)" ;
    ke-wp:pathwayId "WP4864" ;
    ke-wp:pathwayTitle "Host-pathogen interaction of human coronaviruses - apoptosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:dc7b7289-517d-45dc-9f1f-88976fb11f35 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-18T08:08:41"^^xsd:dateTime ;
    dcterms:identifier "dc7b7289-517d-45dc-9f1f-88976fb11f35" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1528" ;
    ke-wp:keyEventName "Fatty Acid Beta Oxidation, Decreased" ;
    ke-wp:pathwayId "WP143" ;
    ke-wp:pathwayTitle "Fatty acid beta-oxidation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:dfa95510-459e-4f2c-8ce9-d8183aee3e00 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-10T11:13:49.668075"^^xsd:dateTime ;
    dcterms:identifier "dfa95510-459e-4f2c-8ce9-d8183aee3e00" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 89" ;
    ke-wp:keyEventName "Synthesis, De Novo Fatty Acid (FA)" ;
    ke-wp:pathwayId "WP357" ;
    ke-wp:pathwayTitle "Fatty acid biosynthesis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:e762a290-66f0-4db1-8f1a-8380420e9bde a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T08:48:42.278147"^^xsd:dateTime ;
    dcterms:identifier "e762a290-66f0-4db1-8f1a-8380420e9bde" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1103" ;
    ke-wp:keyEventName "Inhibition, Cyclooxygenase 1 activity" ;
    ke-wp:pathwayId "WP4719" ;
    ke-wp:pathwayTitle "Eicosanoid metabolism via cyclooxygenases (COX)" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:ebe94629-c5aa-44a8-86fb-6da0f48ce9b6 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-19T09:44:12"^^xsd:dateTime ;
    dcterms:identifier "ebe94629-c5aa-44a8-86fb-6da0f48ce9b6" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1632" ;
    ke-wp:keyEventName "Increase in reactive oxygen and nitrogen species (RONS)" ;
    ke-wp:pathwayId "WP5233" ;
    ke-wp:pathwayTitle "Arsenic metabolism and reactive oxygen species generation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:ed25d939-b504-4377-8a00-a45f061c26ec a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-11T11:29:39"^^xsd:dateTime ;
    dcterms:identifier "ed25d939-b504-4377-8a00-a45f061c26ec" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 188" ;
    ke-wp:keyEventName "Neuroinflammation" ;
    ke-wp:pathwayId "WP5485" ;
    ke-wp:pathwayTitle "Post-COVID neuroinflammation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:edd06611-79dd-47ca-8de0-69b360072333 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13T06:10:35"^^xsd:dateTime ;
    dcterms:identifier "edd06611-79dd-47ca-8de0-69b360072333" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 654" ;
    ke-wp:keyEventName "KE 654 - Decreased testosterone by the fetal Leydig cells, Activation by other glucocorticoid receptor agonists" ;
    ke-wp:pathwayId "WP49" ;
    ke-wp:pathwayTitle "IL2 signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:ee3080d6-845b-48a6-8348-2f786753a3a6 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-10T11:13:25.964476"^^xsd:dateTime ;
    dcterms:identifier "ee3080d6-845b-48a6-8348-2f786753a3a6" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 860" ;
    ke-wp:keyEventName "Decreased, Mitochondrial Fatty Acid Beta Oxidation" ;
    ke-wp:pathwayId "WP368" ;
    ke-wp:pathwayTitle "Mitochondrial long chain fatty acid beta-oxidation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:f0d767c3-ea71-40db-a6c1-865aafec9378 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:01.534945"^^xsd:dateTime ;
    dcterms:identifier "f0d767c3-ea71-40db-a6c1-865aafec9378" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1096" ;
    ke-wp:keyEventName "Increased, blood uric acid concentration" ;
    ke-wp:pathwayId "WP497" ;
    ke-wp:pathwayTitle "Urea cycle and metabolism of amino groups" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:f2676c64-7197-42b7-966e-7a08e33f1b7e a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:15:03.936992"^^xsd:dateTime ;
    dcterms:identifier "f2676c64-7197-42b7-966e-7a08e33f1b7e" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 40" ;
    ke-wp:keyEventName "Mitochondrial ATP production, decreased" ;
    ke-wp:pathwayId "WP5239" ;
    ke-wp:pathwayTitle "Lac-Phe pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:f2ecea3e-2881-4389-a0b5-ec5e2ccc5ad8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-13T08:09:29.271039"^^xsd:dateTime ;
    dcterms:identifier "f2ecea3e-2881-4389-a0b5-ec5e2ccc5ad8" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1825" ;
    ke-wp:keyEventName "Increase, Cell death" ;
    ke-wp:pathwayId "WP2513" ;
    ke-wp:pathwayTitle "Nanoparticle triggered regulated necrosis" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:f48d8413-3d7c-4c9f-acf8-1cbcc021a56c a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:40:01.519442"^^xsd:dateTime ;
    dcterms:identifier "f48d8413-3d7c-4c9f-acf8-1cbcc021a56c" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 2119" ;
    ke-wp:keyEventName "Increase, Insulin resistance" ;
    ke-wp:pathwayId "WP481" ;
    ke-wp:pathwayTitle "Insulin signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:f5410fcd-5287-4519-b2f0-15d62a8a1544 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-11T18:35:50.387531"^^xsd:dateTime ;
    dcterms:identifier "f5410fcd-5287-4519-b2f0-15d62a8a1544" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 177" ;
    ke-wp:keyEventName "Increase, Mitochondrial dysfunction" ;
    ke-wp:pathwayId "WP5241" ;
    ke-wp:pathwayTitle "Mitochondrial beta-oxidation" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:f6e918fc-193c-423a-8420-182f288a3af8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-05-11T18:33:40.576462"^^xsd:dateTime ;
    dcterms:identifier "f6e918fc-193c-423a-8420-182f288a3af8" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 177" ;
    ke-wp:keyEventName "Increase, Mitochondrial dysfunction" ;
    ke-wp:pathwayId "WP4324" ;
    ke-wp:pathwayTitle "Mitochondrial complex I assembly model OXPHOS system" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:fa12d400-ac9c-471c-b344-4ebdb9fe0fcb a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:14:43.096653"^^xsd:dateTime ;
    dcterms:identifier "fa12d400-ac9c-471c-b344-4ebdb9fe0fcb" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 570" ;
    ke-wp:keyEventName "Accumulation, Damaged mitochondrial DNA" ;
    ke-wp:pathwayId "WP4946" ;
    ke-wp:pathwayTitle "DNA repair pathways, full network" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:fa9c36da-b698-44e0-8365-e30a7933c243 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-03-16T14:15:12.513985"^^xsd:dateTime ;
    dcterms:identifier "fa9c36da-b698-44e0-8365-e30a7933c243" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1271" ;
    ke-wp:keyEventName "Increase, Transforming growth factor-beta signaling" ;
    ke-wp:pathwayId "WP560" ;
    ke-wp:pathwayTitle "TGF-beta receptor signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:fbbeec70-e0e0-40bb-9534-191f96e0c3dc a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:38:34.937295"^^xsd:dateTime ;
    dcterms:identifier "fbbeec70-e0e0-40bb-9534-191f96e0c3dc" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 2009" ;
    ke-wp:keyEventName "Activation of inflammation pathway" ;
    ke-wp:pathwayId "WP453" ;
    ke-wp:pathwayTitle "Inflammatory response pathway" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:fc3dd7f8-778e-40fb-ae9e-10b4637cef93 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T16:58:33.573911"^^xsd:dateTime ;
    dcterms:identifier "fc3dd7f8-778e-40fb-ae9e-10b4637cef93" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 459" ;
    ke-wp:keyEventName "Increased, Liver Steatosis" ;
    ke-wp:pathwayId "WP5061" ;
    ke-wp:pathwayTitle "Fatty acid transporters" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .

mapping:ff784cdd-b8a1-4245-84af-6db3decdba23 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "github:marvinm2" ;
    dcterms:date "2026-04-12T21:39:28.789358"^^xsd:dateTime ;
    dcterms:identifier "ff784cdd-b8a1-4245-84af-6db3decdba23" ;
    ke-wp:aopWikiSnapshotDate "2026-05-06"^^xsd:date ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1271" ;
    ke-wp:keyEventName "Activation of TGF-β signaling" ;
    ke-wp:pathwayId "WP5382" ;
    ke-wp:pathwayTitle "TGFB / Smad signaling" ;
    ke-wp:wpReleaseDate "2026-05-10"^^xsd:date .