https://ke-wp-mapping.org/mapping/00c68fec-ca92-4eae-87af-e45f5d7fd129
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:13:58.705415
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 178
key event name: Mitochondrial electron transport chain, disrupted
pathway id: WP111
pathway title: Electron transport chain: OXPHOS system in mitochondria
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/0138f004-96d7-40ba-97c7-a1e74eb5cccb
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-09-25T13:19:49
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 468
key event name: Inhibition, PPAR alpha
pathway id: WP2878
pathway title: PPAR-alpha pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/01e32369-e81d-487d-b083-6b7d2e2658f3
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:59:59.791602
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 898
key event name: Disruption, Lysosome
pathway id: WP4923
pathway title: Autophagy
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/02aa0594-f1db-49cc-b940-afc5cb08a8bf
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:22.801171
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1493
key event name: Increased Pro-inflammatory mediators
pathway id: WP453
pathway title: Inflammatory response pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/03b07f97-c4ff-4c38-8367-4e065237d661
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:59:54.384525
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 898
key event name: Disruption, Lysosome
pathway id: WP183
pathway title: Proteasome degradation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/04a53bdb-bfdb-4419-ae23-f5577a59e4d9
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:14:13.427613
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 40
key event name: Mitochondrial ATP production, decreased
pathway id: WP5049
pathway title: Glycolysis in senescence
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/04ac87f4-63bf-497a-b769-bf30ec13471d
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:15:29.509837
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 122
key event name: Increase, Glucocorticoid receptor activation
pathway id: WP2880
pathway title: Glucocorticoid receptor pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/059a1c15-b17b-486a-9a3d-ebd7d2dc55c6
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:14:35.064635
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 664
key event name: Overwhelmed, Mitochondrial DNA repair mechanisms
pathway id: WP4946
pathway title: DNA repair pathways, full network
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/06594da6-55e3-4478-af0e-0ecff614bdd8
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:59.517518
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 829
key event name: Damage, Lipid bilayer
pathway id: WP5584
pathway title: Signaling lipids
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/081fd464-efbf-4a29-8cc8-a250d30996b8
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T08:48:52.213466
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1392
key event name: Increase, Oxidative Stress
pathway id: WP5477
pathway title: Molecular pathway for oxidative stress
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/0b2bbce5-21b2-444c-9e0c-f83379970b36
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:14:26.847026
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1825
key event name: Increase, Cell death
pathway id: WP4923
pathway title: Autophagy
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/0b8e0188-4a6d-4808-a9a2-9b0d0177f741
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-07T19:40:47
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 889
key event name: Proteostasis, impaired
pathway id: WP4918
pathway title: Cellular proteostasis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/0bad2bc9-8022-4a21-943e-60bce8096e80
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:43.862998
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 465
key event name: Increased, Fatty acid influx
pathway id: WP5061
pathway title: Fatty acid transporters
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/103f9312-a5db-4d28-b6f1-9c46cf1ac8e8
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-10T11:13:32.167453
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 474
key event name: Down Regulation, HMGCS2
pathway id: WP4718
pathway title: Cholesterol metabolism with Bloch and Kandutsch-Russell pathways
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/10ccb991-68a7-49c9-be6c-03adedde9256
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:06.207950
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 837
key event name: Occurrence, Cytoplasmic vacuolization (kupffer cell)
pathway id: WP3965
pathway title: Lipid metabolism pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/11d306d0-8f83-44e2-a514-afdeb998e65f
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-25T09:45:55
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 87
key event name: Release, Cytokine
pathway id: WP530
pathway title: Cytokines and inflammatory response
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/142fe8a3-2cd0-48d1-98b9-c3f891a2e0b8
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T09:38:28.259004
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1365
key event name: Increase, Apoptosis
pathway id: WP254
pathway title: Apoptosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/14929bcf-8df9-4685-a372-f941487abf37
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:09:18.273157
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1195
key event name: modulation, Extracellular Matrix Composition
pathway id: WP5382
pathway title: TGFB / Smad signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/16445bb4-4543-4cbf-bb87-46cd02c3aedb
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:59:47.408042
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1539
key event name: Endocytotic lysosomal uptake
pathway id: WP4655
pathway title: Cytosolic DNA-sensing pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/1bb5d670-625b-4695-8d00-ceccdcb0bd91
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:28.797927
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 2406
key event name: Increase, Regenerative nodule formation
pathway id: WP3932
pathway title: Focal adhesion: PI3K-Akt-mTOR-signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/21deba79-e0c2-4a01-beb0-7680d85e964f
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-10T11:13:43.598526
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 115
key event name: Increase, FA Influx
pathway id: WP5061
pathway title: Fatty acid transporters
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/21f40e2d-5f36-4336-a62e-dc2dafdef26a
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-23T10:06:21.147901
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 227
key event name: Activation, PPARα
pathway id: WP2878
pathway title: PPAR-alpha pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/21f99235-bf4a-4046-b775-bb98b368157d
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:26.778742
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 459
key event name: Increased, Liver Steatosis
pathway id: WP3965
pathway title: Lipid metabolism pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/27373650-58e1-4f1a-aaba-c75f4ecf9fdb
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-01T12:25:21.759903
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 105
key event name: Inhibition, Mitochondrial Electron Transport Chain Complexes
pathway id: WP111
pathway title: Electron transport chain: OXPHOS system in mitochondria
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/2762aab1-afb2-4492-a3f2-6111c21fb8d7
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T06:05:59
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 25
key event name: KE 25 - Agonism, Androgen receptor
pathway id: WP272
pathway title: Blood clotting cascade
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/2b0b07b3-78a7-4845-a30d-ee5d15ff8439
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T06:07:52
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 345
key event name: KE 345 - N/A, Liver Steatosis
pathway id: WP4010
pathway title: Liver steatosis adverse outcome pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/2c6fac33-0002-407a-99e6-2bfc17bd24c4
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:39.435051
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 2408
key event name: Increase, Adipose lipolysis
pathway id: WP236
pathway title: Adipogenesis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/30c7ed6a-6344-4d87-9792-467ed95646db
type: KeyEventPathwayMapping
creator: guest-test-participant
date: 2026-02-17T21:09:14
aop wiki snapshot date: 2026-05-06
confidence level: low
key event id: KE 123
key event name: Test Key Event
pathway id: WP1234
pathway title: Test Pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/342f57b2-6a1b-4163-8e72-afbfbebf3e2a
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-04T15:40:06.892136
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 55
key event name: Increase, Cell injury/death
pathway id: WP254
pathway title: Apoptosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/376fba0c-4479-4239-9935-c76484eb12cd
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:05.530964
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 18
key event name: Activation, AhR
pathway id: WP2873
pathway title: Aryl hydrocarbon receptor pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/3800a94e-acc6-4463-a8d3-d508911cc4e6
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:38:49.861003
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 833
key event name: Occurrence, Cytoplasmic vacuolization (hepatocyte)
pathway id: WP3965
pathway title: Lipid metabolism pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/38705c21-ae84-4678-b59e-e6405de3b187
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-14T06:51:54
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 28
key event name: Reduction, Angiogenesis
pathway id: WP1539
pathway title: Angiogenesis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/39928d1c-c27c-46e4-baa4-1eaa957848e3
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T17:00:18.159156
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 265
key event name: Activation, Stellate cells
pathway id: WP560
pathway title: TGF-beta receptor signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/3acb794f-7ca9-43ea-a33d-6523007b0534
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:09:14.731814
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1395
key event name: Liver Cancer
pathway id: WP3646
pathway title: Hepatitis C and hepatocellular carcinoma
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/3bd9947e-f807-4d55-9b52-02b9c756b187
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T08:48:46.883531
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1115
key event name: Increase, Reactive oxygen species
pathway id: WP5477
pathway title: Molecular pathway for oxidative stress
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/3cbd2aee-253f-4c71-baed-dae19f96ddb2
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T11:59:00.133709
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1194
key event name: Increase, DNA damage
pathway id: WP707
pathway title: DNA damage response
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/40838948-42b5-49ce-acef-8bd45cd08ff6
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:38:43.255042
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1262
key event name: Apoptosis
pathway id: WP254
pathway title: Apoptosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/40b9cce4-e978-4516-9312-8e0766eb745c
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-25T12:29:17.416054
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1105
key event name: Occurrence, renal ischemia
pathway id: WP4298
pathway title: Acute viral myocarditis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/413c7311-b688-4f3c-ae3a-b1df32a18fc7
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-10-21T06:41:17
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 111
key event name: Agonism, Estrogen receptor
pathway id: WP2881
pathway title: Estrogen receptor pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/427e6bb4-caa2-450d-ba19-4ea90c85907d
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:22.099238
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1815
key event name: Increase, Endoplasmic reticulum stress
pathway id: WP4925
pathway title: Unfolded protein response
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/42d1c812-5b76-4a3f-88a7-d486368625d4
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-10-01T16:57:43
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 12
key event name: Acetylcholinesterase (AchE) Inhibition
pathway id: WP1602
pathway title: Nicotine effect on dopaminergic neurons
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/4328b6f0-edc4-4d5a-ad46-3e5316b303ad
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T17:00:45.616529
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1493
key event name: Increased Pro-inflammatory mediators
pathway id: WP530
pathway title: Cytokines and inflammatory response
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/45008303-2c25-4ada-8068-744793322926
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:16.453079
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 831
key event name: Disturbance, Lysosomal function
pathway id: WP183
pathway title: Proteasome degradation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/467a0fbc-a4fa-4653-a1b7-2c99f94f18f2
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:14.239277
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1395
key event name: Liver Cancer
pathway id: WP5434
pathway title: Cancer pathways
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/468515f6-3799-43c3-9cc4-2892ed266990
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:14:55.641134
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 40
key event name: Mitochondrial ATP production, decreased
pathway id: WP5241
pathway title: Mitochondrial beta-oxidation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/4ac6be90-26fe-4789-a7fc-bf1a67ee53fd
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:47.951073
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1740
key event name: Induced dysregulation of ACE2
pathway id: WP554
pathway title: ACE inhibitor pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/4bc9372a-3b46-4fe9-82d3-685e3c05620b
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-01T12:25:08.715823
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 177
key event name: Increase, Mitochondrial dysfunction
pathway id: WP5507
pathway title: Mitochondrial carrier deficiency associated with shuttle disturbances
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/4f329e87-3247-4a73-90c2-bae7f78a9350
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:09:02.741594
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 840
key event name: Formation, Liver fibrosis
pathway id: WP3980
pathway title: Protein alkylation leading to liver fibrosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/4f78f4fb-e5db-43ae-84dc-29ac03b27c14
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:18.788438
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1306
key event name: Increase, De novo lipogenesis
pathway id: WP3965
pathway title: Lipid metabolism pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/535d741b-8f8c-4201-ae06-ea6cd06bdafa
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-23T10:05:07.498816
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 269
key event name: Induction, Sustained Cell Proliferation
pathway id: WP5475
pathway title: Hallmark of cancer: sustaining proliferative signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/58a8c278-8efe-4f81-bf80-1fae402460ce
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-01T12:25:15.125934
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 819
key event name: Decreased, Glomerular filtration
pathway id: WP2572
pathway title: Primary focal segmental glomerulosclerosis (FSGS)
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/5cf9cbb2-55ee-4cc8-a14c-04ee235275dd
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:56.142557
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 344
key event name: N/A, Liver fibrosis
pathway id: WP3980
pathway title: Protein alkylation leading to liver fibrosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/618c2abc-12a9-4091-ade3-4376740f7836
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:56.163068
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1743
key event name: Increase plasma Ang II
pathway id: WP4756
pathway title: Renin-angiotensin-aldosterone system (RAAS)
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/66ff7c41-d4c0-4555-8ac2-6e96f8941d6d
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:25.346790
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 2412
key event name: Increase, Hepatic intracellular active glucocorticoids
pathway id: WP5280
pathway title: Glucocorticoid biosynthesis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/67cd49e4-bea7-4471-bf83-b693457e821a
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:10.414920
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 838
key event name: Induction, Microvesicular fat
pathway id: WP4149
pathway title: White fat cell differentiation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/6bb30d07-942e-45e0-a8be-113b8c4a1ee7
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-11T18:32:08.534730
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 177
key event name: Increase, Mitochondrial dysfunction
pathway id: WP78
pathway title: TCA cycle (aka Krebs or citric acid cycle)
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/6c09bce6-b0a3-4eec-9a3c-cdc29e340a27
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-11T18:16:47.739924
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1825
key event name: Increase, Cell death
pathway id: WP1772
pathway title: Apoptosis modulation and signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/6d02cf1e-9d5d-4ff9-b653-11a8062d33b7
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:02.169585
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 836
key event name: Occurrence, Cytoplasmic vacuolization (Bile duct cell)
pathway id: WP3965
pathway title: Lipid metabolism pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/742b5962-500e-405b-ac14-240b7a6f666e
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-12T10:40:08
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 188
key event name: Neuroinflammation
pathway id: WP4919
pathway title: Neuroinflammation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/75add0dc-cf87-4893-9204-3a49cbd0a961
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:12.693803
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 2407
key event name: Increase, Cirrhosis
pathway id: WP5382
pathway title: TGFB / Smad signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/772e8aa1-85ff-41ba-a3da-ce139f3adc5b
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T11:59:04.831564
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1392
key event name: Oxidative Stress
pathway id: WP408
pathway title: Oxidative stress response
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/79ad02a0-a157-4746-aa8d-070f4db8240e
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T05:42:58
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 25
key event name: KE 25 - Agonism, Androgen receptor
pathway id: WP138
pathway title: Androgen receptor signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/85f40708-4bce-4160-9235-b4ff5ab0fb06
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T17:00:39.362429
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1492
key event name: Tissue resident cell activation
pathway id: WP560
pathway title: TGF-beta receptor signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/8aba0b0c-1d85-4ba8-8dab-dc1bd303b33a
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-24T13:29:57.881637
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1283
key event name: Activation, TGF-beta pathway
pathway id: WP560
pathway title: TGF-beta receptor signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/8c6b2d57-e547-4573-9f3b-5aa50585b635
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:38:30.437906
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 870
key event name: Increase, Cell Proliferation
pathway id: WP179
pathway title: Cell cycle
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/8e02b782-6c64-4874-afb7-0b955c6f3b53
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:38:54.089966
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 831
key event name: Disturbance, Lysosomal function
pathway id: WP4923
pathway title: Autophagy
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/90896f40-d1ea-4eb4-b1b6-fcebc7d06617
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:33.341949
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 828
key event name: Inhibition, Phospholipase A
pathway id: WP3965
pathway title: Lipid metabolism pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/91163daf-9bd8-48d5-b01e-4d958ee01496
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T17:00:06.435968
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 68
key event name: Accumulation, Collagen
pathway id: WP560
pathway title: TGF-beta receptor signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/935eb43f-3226-4cf1-abce-d38cbe9f91c2
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T08:48:57.442432
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 177
key event name: Increase, Mitochondrial dysfunction
pathway id: WP623
pathway title: Oxidative phosphorylation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/93fce828-81cd-4305-b7ba-1b36ca0650f5
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-01T12:25:30.831620
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 926
key event name: Oxidation, Glutathione (To be considered with MIE)
pathway id: WP100
pathway title: Glutathione metabolism
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/94bdac0c-dbd6-4680-b6ed-f52a9fccad74
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T17:00:26.988024
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1494
key event name: Leukocyte recruitment/activation
pathway id: WP4542
pathway title: Leukocyte-intrinsic Hippo pathway functions
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/97e56fdd-c416-46a5-86bd-02df2ef90cc9
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:40:09.684399
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 839
key event name: Formation, Mallory body
pathway id: WP183
pathway title: Proteasome degradation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/9e3bc5f4-7243-41fd-afd6-f70cf049e801
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:20.827052
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1489
key event name: N/A, Steatohepatisis
pathway id: WP453
pathway title: Inflammatory response pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/9e6f4b97-1fea-4db3-b6e0-4abd4f060cc4
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:38:39.272632
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1967
key event name: Pyroptosis
pathway id: WP453
pathway title: Inflammatory response pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/9f064b32-a4ab-4c50-8f64-4db70aea6f7b
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-01-13T13:14:59
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 55
key event name: Increase, Cell injury/death
pathway id: WP2507
pathway title: Nanomaterial induced apoptosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/a24e3558-b5e3-4f87-ad93-f123cf34c8bb
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:09:25.582533
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1096
key event name: Increased, blood uric acid concentration
pathway id: WP4595
pathway title: Urea cycle and associated pathways
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/a28dd624-1171-4780-bc8c-1c17fd83004d
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:42.802911
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 2405
key event name: Increase, Hepatocellular lipotoxicity
pathway id: WP5323
pathway title: Fatty acid and lipoprotein transport in hepatocytes
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/a47b791d-61c4-4f9e-9db4-92e49c230ee4
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:08:51.097651
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 839
key event name: Formation, Mallory body
pathway id: WP254
pathway title: Apoptosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/a5c102fa-7b60-48fa-90e3-b7b811e583af
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T11:59:09.512244
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1825
key event name: Increase, Cell death
pathway id: WP254
pathway title: Apoptosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/a6638a2b-0e38-4d4f-9e09-89b36b530398
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-25T12:29:33.602913
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 40
key event name: Mitochondrial ATP production, decreased
pathway id: WP391
pathway title: Mitochondrial gene expression
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/a729c940-c492-4161-a76f-eab6af7d8ce1
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:42.977046
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1852
key event name: Increased Ang II type 1 receptor (AT1R)
pathway id: WP5036
pathway title: Angiotensin II receptor type 1 pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/a7c2e4cc-ef2d-4c74-8e4a-3b4dc8a3aa2a
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-25T12:29:13.399987
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 50
key event name: Increase, Ca++ (intracellular)
pathway id: WP254
pathway title: Apoptosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/a7f286e7-0afc-49f9-8cc0-50c6c18a0f20
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:40:05.470862
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 134
key event name: Increase, Kupffer cell activation
pathway id: WP530
pathway title: Cytokines and inflammatory response
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/adf9941e-23d8-45c9-8044-7fa2a5b7d40c
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-10T11:13:37.747859
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 471
key event name: Inhibition, FoxA2
pathway id: WP5066
pathway title: FOXA2 pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/affc3bd7-b0e5-4e1c-b94e-927a45f0d5b4
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:52.473186
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 459
key event name: Increased, Liver Steatosis
pathway id: WP143
pathway title: Fatty acid beta-oxidation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/b02b5b42-cbde-4ced-8bd1-a798861b4260
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:59:13.146695
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1501
key event name: Increased, extracellular matrix deposition
pathway id: WP428
pathway title: Wnt signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/b21ac548-dd63-480b-9199-7f9391587af8
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T11:59:13.592007
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 149
key event name: Increase, Inflammation
pathway id: WP530
pathway title: Cytokines and inflammatory response
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/b3b9ddea-5cfa-4bc5-a8f7-8e74755e2675
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:15:20.365434
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 459
key event name: Increase, Liver steatosis
pathway id: WP4010
pathway title: Liver steatosis adverse outcome pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/b411eceb-1489-47b9-8d06-6ea04a5dd5eb
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:38.805596
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 2406
key event name: Increase, Regenerative nodule formation
pathway id: WP428
pathway title: Wnt signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/b53d61ea-d3d8-45ea-b44c-309247dc7d28
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T05:47:13
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 17
key event name: KE 17 - Altered gene expression, AHR nuclear translocator (ARNT)-dependent pathway
pathway id: WP2882
pathway title: Nuclear receptors meta-pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/b66987de-ae63-418e-a2a2-1d7562174851
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-01T12:25:51.610626
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 9
key event name: Activation, 5HT2c
pathway id: WP5239
pathway title: Lac-Phe pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/b684145d-c10c-45cd-bcd2-d92eb80479e3
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:38:58.096891
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 835
key event name: Occurrence, Ballooning degeneration (hepatocyte)
pathway id: WP4925
pathway title: Unfolded protein response
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/b8eeaa97-12cc-466d-b735-2fdfb03d3e22
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T05:42:58
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 25
key event name: KE 25 - Agonism, Androgen receptor
pathway id: WP2263
pathway title: Androgen receptor network in prostate cancer
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/bb7b4563-1c93-4822-a3dc-3f77b1f509e1
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-25T12:29:38.622413
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1104
key event name: Decreased, Prostaglandin F2alpha concentration, plasma
pathway id: WP98
pathway title: Prostaglandin synthesis and regulation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/bbc8a46d-3b48-4b72-8845-a1fab1e4cc3a
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T06:18:18
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 2336
key event name: Increase, SREBF1
pathway id: WP22
pathway title: IL9 signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/bc215442-82fc-4c24-8af1-6aa69e21e85a
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:09:21.952584
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1306
key event name: Increase, De novo lipogenesis
pathway id: WP236
pathway title: Adipogenesis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/c002a994-b638-4c79-bbf7-76a578f527a0
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T06:13:34
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 2072
key event name: Increase, Mitochondrial swelling
pathway id: WP5241
pathway title: Mitochondrial beta-oxidation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/c11425fd-d781-4f36-815d-d8931a5d5c8c
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-10-02T11:08:38
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 10
key event name: Acetylcholine accumulation in synapses
pathway id: WP528
pathway title: Acetylcholine synthesis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/c2c192fb-179d-4e1a-b36e-938c134a6cd2
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:59:22.777421
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1501
key event name: Increased, extracellular matrix deposition
pathway id: WP560
pathway title: TGF-beta receptor signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/c843f1b7-61d2-4ee6-9e1a-eea2631c6012
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:09:11.297665
aop wiki snapshot date: 2026-05-06
confidence level: low
key event id: KE 2410
key event name: Increase, 11β-Hydroxysteroid dehydrogenase type 1 activity
pathway id: WP2880
pathway title: Glucocorticoid receptor pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/ced7c569-aea1-4a72-b06b-223957a874d9
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:09:06.437923
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 149
key event name: Increase, Inflammation
pathway id: WP453
pathway title: Inflammatory response pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/d03eb198-e060-4046-9349-038d809dcaea
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-10-01T16:38:58
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 79
key event name: Inhibition, Cyclooxygenase activity
pathway id: WP4719
pathway title: Eicosanoid metabolism via cyclooxygenases (COX)
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/d16cb071-1f02-4089-989b-939c1391612e
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T05:47:13
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 17
key event name: KE 17 - Altered gene expression, AHR nuclear translocator (ARNT)-dependent pathway
pathway id: WP2289
pathway title: Drug induction of bile acid pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/d6d3f689-00ab-4f9a-8c49-e3a1e35a1547
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T08:48:33.834124
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 281
key event name: Thyroxine (T4) in serum, Decreased
pathway id: WP1981
pathway title: Thyroxine (thyroid hormone) production
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/d7e879d1-c79f-4fc0-b6c8-6421d3a4a4fc
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:59:30.158836
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 244
key event name: Alkylation, Protein
pathway id: WP3980
pathway title: Protein alkylation leading to liver fibrosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/db828dc6-9737-4e63-ba87-c6d45ad4ae8d
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-25T12:29:07.474042
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 709
key event name: Increase, Cytotoxicity (renal tubular cell)
pathway id: WP4864
pathway title: Host-pathogen interaction of human coronaviruses - apoptosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/dc7b7289-517d-45dc-9f1f-88976fb11f35
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-18T08:08:41
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1528
key event name: Fatty Acid Beta Oxidation, Decreased
pathway id: WP143
pathway title: Fatty acid beta-oxidation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/dfa95510-459e-4f2c-8ce9-d8183aee3e00
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-10T11:13:49.668075
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 89
key event name: Synthesis, De Novo Fatty Acid (FA)
pathway id: WP357
pathway title: Fatty acid biosynthesis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/e762a290-66f0-4db1-8f1a-8380420e9bde
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-03-03T08:48:42.278147
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1103
key event name: Inhibition, Cyclooxygenase 1 activity
pathway id: WP4719
pathway title: Eicosanoid metabolism via cyclooxygenases (COX)
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/ebe94629-c5aa-44a8-86fb-6da0f48ce9b6
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-19T09:44:12
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1632
key event name: Increase in reactive oxygen and nitrogen species (RONS)
pathway id: WP5233
pathway title: Arsenic metabolism and reactive oxygen species generation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/ed25d939-b504-4377-8a00-a45f061c26ec
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-11T11:29:39
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 188
key event name: Neuroinflammation
pathway id: WP5485
pathway title: Post-COVID neuroinflammation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/edd06611-79dd-47ca-8de0-69b360072333
type: KeyEventPathwayMapping
creator: marvinm2
date: 2025-08-13T06:10:35
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 654
key event name: KE 654 - Decreased testosterone by the fetal Leydig cells, Activation by other glucocorticoid receptor agonists
pathway id: WP49
pathway title: IL2 signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/ee3080d6-845b-48a6-8348-2f786753a3a6
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-10T11:13:25.964476
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 860
key event name: Decreased, Mitochondrial Fatty Acid Beta Oxidation
pathway id: WP368
pathway title: Mitochondrial long chain fatty acid beta-oxidation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/f0d767c3-ea71-40db-a6c1-865aafec9378
type: KeyEventPathwayMapping
creator: marvinm2
date: 2026-02-25T12:29:01.534945
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 1096
key event name: Increased, blood uric acid concentration
pathway id: WP497
pathway title: Urea cycle and metabolism of amino groups
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/f2676c64-7197-42b7-966e-7a08e33f1b7e
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:15:03.936992
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 40
key event name: Mitochondrial ATP production, decreased
pathway id: WP5239
pathway title: Lac-Phe pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/f2ecea3e-2881-4389-a0b5-ec5e2ccc5ad8
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-13T08:09:29.271039
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1825
key event name: Increase, Cell death
pathway id: WP2513
pathway title: Nanoparticle triggered regulated necrosis
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/f48d8413-3d7c-4c9f-acf8-1cbcc021a56c
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:40:01.519442
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 2119
key event name: Increase, Insulin resistance
pathway id: WP481
pathway title: Insulin signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/f5410fcd-5287-4519-b2f0-15d62a8a1544
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-11T18:35:50.387531
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 177
key event name: Increase, Mitochondrial dysfunction
pathway id: WP5241
pathway title: Mitochondrial beta-oxidation
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/f6e918fc-193c-423a-8420-182f288a3af8
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-05-11T18:33:40.576462
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 177
key event name: Increase, Mitochondrial dysfunction
pathway id: WP4324
pathway title: Mitochondrial complex I assembly model OXPHOS system
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/fa12d400-ac9c-471c-b344-4ebdb9fe0fcb
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:14:43.096653
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 570
key event name: Accumulation, Damaged mitochondrial DNA
pathway id: WP4946
pathway title: DNA repair pathways, full network
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/fa9c36da-b698-44e0-8365-e30a7933c243
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-03-16T14:15:12.513985
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1271
key event name: Increase, Transforming growth factor-beta signaling
pathway id: WP560
pathway title: TGF-beta receptor signaling
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/fbbeec70-e0e0-40bb-9534-191f96e0c3dc
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:38:34.937295
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 2009
key event name: Activation of inflammation pathway
pathway id: WP453
pathway title: Inflammatory response pathway
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/fc3dd7f8-778e-40fb-ae9e-10b4637cef93
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T16:58:33.573911
aop wiki snapshot date: 2026-05-06
confidence level: medium
key event id: KE 459
key event name: Increased, Liver Steatosis
pathway id: WP5061
pathway title: Fatty acid transporters
wp release date: 2026-05-10

https://ke-wp-mapping.org/mapping/ff784cdd-b8a1-4245-84af-6db3decdba23
type: KeyEventPathwayMapping
creator: github:marvinm2
date: 2026-04-12T21:39:28.789358
aop wiki snapshot date: 2026-05-06
confidence level: high
key event id: KE 1271
key event name: Activation of TGF-β signaling
pathway id: WP5382
pathway title: TGFB / Smad signaling
wp release date: 2026-05-10