Mitochondrial electron transport chain, disrupted
Electron transport chain: OXPHOS system in mitochondria
Increase, Glucocorticoid receptor activation
Overwhelmed, Mitochondrial DNA repair mechanisms
Cholesterol metabolism with Bloch and Kandutsch-Russell pathways
Occurrence, Cytoplasmic vacuolization (kupffer cell)
modulation, Extracellular Matrix Composition
Inhibition, Mitochondrial Electron Transport Chain Complexes
Occurrence, Cytoplasmic vacuolization (hepatocyte)
Hepatitis C and hepatocellular carcinoma
Mitochondrial carrier deficiency associated with shuttle disturbances
Protein alkylation leading to liver fibrosis
Hallmark of cancer: sustaining proliferative signaling
Primary focal segmental glomerulosclerosis (FSGS)
Renin-angiotensin-aldosterone system (RAAS)
Increase, Hepatic intracellular active glucocorticoids
TCA cycle (aka Krebs or citric acid cycle)
Occurrence, Cytoplasmic vacuolization (Bile duct cell)
Oxidation, Glutathione (To be considered with MIE)
Leukocyte-intrinsic Hippo pathway functions
Increased, blood uric acid concentration
Fatty acid and lipoprotein transport in hepatocytes
Increased, extracellular matrix deposition
KE 17 - Altered gene expression, AHR nuclear translocator (ARNT)-dependent pathway
Occurrence, Ballooning degeneration (hepatocyte)
Androgen receptor network in prostate cancer
Decreased, Prostaglandin F2alpha concentration, plasma
Increase, 11β-Hydroxysteroid dehydrogenase type 1 activity
Eicosanoid metabolism via cyclooxygenases (COX)
Increase, Cytotoxicity (renal tubular cell)
Host-pathogen interaction of human coronaviruses - apoptosis
Increase in reactive oxygen and nitrogen species (RONS)
Arsenic metabolism and reactive oxygen species generation
KE 654 - Decreased testosterone by the fetal Leydig cells, Activation by other glucocorticoid receptor agonists
Decreased, Mitochondrial Fatty Acid Beta Oxidation
Mitochondrial long chain fatty acid beta-oxidation
Urea cycle and metabolism of amino groups
Nanoparticle triggered regulated necrosis
Mitochondrial complex I assembly model OXPHOS system
Increase, Transforming growth factor-beta signaling