@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix ke-wp: <https://ke-wp-mapping.org/vocab#> .
@prefix mapping: <https://ke-wp-mapping.org/mapping/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

mapping:0138f004-96d7-40ba-97c7-a1e74eb5cccb a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-09-25 13:19:49"^^xsd:dateTime ;
    dcterms:identifier "0138f004-96d7-40ba-97c7-a1e74eb5cccb" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 468" ;
    ke-wp:keyEventName "Inhibition, PPAR alpha" ;
    ke-wp:pathwayId "WP2878" ;
    ke-wp:pathwayTitle "PPAR-alpha pathway" .

mapping:081fd464-efbf-4a29-8cc8-a250d30996b8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T08:48:52.213466"^^xsd:dateTime ;
    dcterms:identifier "081fd464-efbf-4a29-8cc8-a250d30996b8" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1392" ;
    ke-wp:keyEventName "Increase, Oxidative Stress" ;
    ke-wp:pathwayId "WP5477" ;
    ke-wp:pathwayTitle "Molecular pathway for oxidative stress" .

mapping:0b8e0188-4a6d-4808-a9a2-9b0d0177f741 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-07 19:40:47"^^xsd:dateTime ;
    dcterms:identifier "0b8e0188-4a6d-4808-a9a2-9b0d0177f741" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 889" ;
    ke-wp:keyEventName "Proteostasis, impaired" ;
    ke-wp:pathwayId "WP4918" ;
    ke-wp:pathwayTitle "Cellular proteostasis" .

mapping:11d306d0-8f83-44e2-a514-afdeb998e65f a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-25 09:45:55"^^xsd:dateTime ;
    dcterms:identifier "11d306d0-8f83-44e2-a514-afdeb998e65f" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 87" ;
    ke-wp:keyEventName "Release, Cytokine" ;
    ke-wp:pathwayId "WP530" ;
    ke-wp:pathwayTitle "Cytokines and inflammatory response" .

mapping:142fe8a3-2cd0-48d1-98b9-c3f891a2e0b8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T09:38:28.259004"^^xsd:dateTime ;
    dcterms:identifier "142fe8a3-2cd0-48d1-98b9-c3f891a2e0b8" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1365" ;
    ke-wp:keyEventName "Increase, Apoptosis" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" .

mapping:1bf9d4cf-5074-47bd-85d9-361d2073da58 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-21 09:57:36"^^xsd:dateTime ;
    dcterms:identifier "1bf9d4cf-5074-47bd-85d9-361d2073da58" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 245" ;
    ke-wp:keyEventName "Activation, PXR/SXR" ;
    ke-wp:pathwayId "WP3851" ;
    ke-wp:pathwayTitle "TLR4 signaling and tolerance" .

mapping:21f40e2d-5f36-4336-a62e-dc2dafdef26a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-23T10:06:21.147901"^^xsd:dateTime ;
    dcterms:identifier "21f40e2d-5f36-4336-a62e-dc2dafdef26a" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 227" ;
    ke-wp:keyEventName "Activation, PPARα" ;
    ke-wp:pathwayId "WP2878" ;
    ke-wp:pathwayTitle "PPAR-alpha pathway" .

mapping:27373650-58e1-4f1a-aaba-c75f4ecf9fdb a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:21.759903"^^xsd:dateTime ;
    dcterms:identifier "27373650-58e1-4f1a-aaba-c75f4ecf9fdb" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 105" ;
    ke-wp:keyEventName "Inhibition, Mitochondrial Electron Transport Chain Complexes" ;
    ke-wp:pathwayId "WP111" ;
    ke-wp:pathwayTitle "Electron transport chain: OXPHOS system in mitochondria" .

mapping:2762aab1-afb2-4492-a3f2-6111c21fb8d7 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13 06:05:59"^^xsd:dateTime ;
    dcterms:identifier "2762aab1-afb2-4492-a3f2-6111c21fb8d7" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 25" ;
    ke-wp:keyEventName "KE 25 - Agonism, Androgen receptor" ;
    ke-wp:pathwayId "WP272" ;
    ke-wp:pathwayTitle "Blood clotting cascade" .

mapping:2b0b07b3-78a7-4845-a30d-ee5d15ff8439 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13 06:07:52"^^xsd:dateTime ;
    dcterms:identifier "2b0b07b3-78a7-4845-a30d-ee5d15ff8439" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 345" ;
    ke-wp:keyEventName "KE 345 - N/A, Liver Steatosis" ;
    ke-wp:pathwayId "WP4010" ;
    ke-wp:pathwayTitle "Liver steatosis adverse outcome pathway" .

mapping:30c7ed6a-6344-4d87-9792-467ed95646db a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "guest-test-participant" ;
    dcterms:date "2026-02-17 21:09:14"^^xsd:dateTime ;
    dcterms:identifier "30c7ed6a-6344-4d87-9792-467ed95646db" ;
    ke-wp:confidenceLevel "low" ;
    ke-wp:keyEventId "KE 123" ;
    ke-wp:keyEventName "Test Key Event" ;
    ke-wp:pathwayId "WP1234" ;
    ke-wp:pathwayTitle "Test Pathway" .

mapping:342f57b2-6a1b-4163-8e72-afbfbebf3e2a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-04T15:40:06.892136"^^xsd:dateTime ;
    dcterms:identifier "342f57b2-6a1b-4163-8e72-afbfbebf3e2a" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 55" ;
    ke-wp:keyEventName "Increase, Cell injury/death" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" .

mapping:38705c21-ae84-4678-b59e-e6405de3b187 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-14 06:51:54"^^xsd:dateTime ;
    dcterms:identifier "38705c21-ae84-4678-b59e-e6405de3b187" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 28" ;
    ke-wp:keyEventName "Reduction, Angiogenesis" ;
    ke-wp:pathwayId "WP1539" ;
    ke-wp:pathwayTitle "Angiogenesis" .

mapping:3bd9947e-f807-4d55-9b52-02b9c756b187 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T08:48:46.883531"^^xsd:dateTime ;
    dcterms:identifier "3bd9947e-f807-4d55-9b52-02b9c756b187" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1115" ;
    ke-wp:keyEventName "Increase, Reactive oxygen species" ;
    ke-wp:pathwayId "WP5477" ;
    ke-wp:pathwayTitle "Molecular pathway for oxidative stress" .

mapping:3cbd2aee-253f-4c71-baed-dae19f96ddb2 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T11:59:00.133709"^^xsd:dateTime ;
    dcterms:identifier "3cbd2aee-253f-4c71-baed-dae19f96ddb2" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1194" ;
    ke-wp:keyEventName "Increase, DNA damage" ;
    ke-wp:pathwayId "WP707" ;
    ke-wp:pathwayTitle "DNA damage response" .

mapping:40b9cce4-e978-4516-9312-8e0766eb745c a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:17.416054"^^xsd:dateTime ;
    dcterms:identifier "40b9cce4-e978-4516-9312-8e0766eb745c" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1105" ;
    ke-wp:keyEventName "Occurrence, renal ischemia" ;
    ke-wp:pathwayId "WP4298" ;
    ke-wp:pathwayTitle "Acute viral myocarditis" .

mapping:413c7311-b688-4f3c-ae3a-b1df32a18fc7 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-10-21 06:41:17"^^xsd:dateTime ;
    dcterms:identifier "413c7311-b688-4f3c-ae3a-b1df32a18fc7" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 111" ;
    ke-wp:keyEventName "Agonism, Estrogen receptor" ;
    ke-wp:pathwayId "WP2881" ;
    ke-wp:pathwayTitle "Estrogen receptor pathway" .

mapping:42d1c812-5b76-4a3f-88a7-d486368625d4 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-10-01 16:57:43"^^xsd:dateTime ;
    dcterms:identifier "42d1c812-5b76-4a3f-88a7-d486368625d4" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 12" ;
    ke-wp:keyEventName "Acetylcholinesterase (AchE) Inhibition" ;
    ke-wp:pathwayId "WP1602" ;
    ke-wp:pathwayTitle "Nicotine effect on dopaminergic neurons" .

mapping:4bc9372a-3b46-4fe9-82d3-685e3c05620b a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:08.715823"^^xsd:dateTime ;
    dcterms:identifier "4bc9372a-3b46-4fe9-82d3-685e3c05620b" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 177" ;
    ke-wp:keyEventName "Increase, Mitochondrial dysfunction" ;
    ke-wp:pathwayId "WP5507" ;
    ke-wp:pathwayTitle "Mitochondrial carrier deficiency associated with shuttle disturbances" .

mapping:535d741b-8f8c-4201-ae06-ea6cd06bdafa a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-23T10:05:07.498816"^^xsd:dateTime ;
    dcterms:identifier "535d741b-8f8c-4201-ae06-ea6cd06bdafa" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 269" ;
    ke-wp:keyEventName "Induction, Sustained Cell Proliferation" ;
    ke-wp:pathwayId "WP5475" ;
    ke-wp:pathwayTitle "Hallmark of cancer: sustaining proliferative signaling" .

mapping:58a8c278-8efe-4f81-bf80-1fae402460ce a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:15.125934"^^xsd:dateTime ;
    dcterms:identifier "58a8c278-8efe-4f81-bf80-1fae402460ce" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 819" ;
    ke-wp:keyEventName "Decreased, Glomerular filtration" ;
    ke-wp:pathwayId "WP2572" ;
    ke-wp:pathwayTitle "Primary focal segmental glomerulosclerosis (FSGS)" .

mapping:742b5962-500e-405b-ac14-240b7a6f666e a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-12 10:40:08"^^xsd:dateTime ;
    dcterms:identifier "742b5962-500e-405b-ac14-240b7a6f666e" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 188" ;
    ke-wp:keyEventName "Neuroinflammation" ;
    ke-wp:pathwayId "WP4919" ;
    ke-wp:pathwayTitle "Neuroinflammation" .

mapping:772e8aa1-85ff-41ba-a3da-ce139f3adc5b a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T11:59:04.831564"^^xsd:dateTime ;
    dcterms:identifier "772e8aa1-85ff-41ba-a3da-ce139f3adc5b" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1392" ;
    ke-wp:keyEventName "Oxidative Stress" ;
    ke-wp:pathwayId "WP408" ;
    ke-wp:pathwayTitle "Oxidative stress response" .

mapping:79ad02a0-a157-4746-aa8d-070f4db8240e a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13 05:42:58"^^xsd:dateTime ;
    dcterms:identifier "79ad02a0-a157-4746-aa8d-070f4db8240e" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 25" ;
    ke-wp:keyEventName "KE 25 - Agonism, Androgen receptor" ;
    ke-wp:pathwayId "WP138" ;
    ke-wp:pathwayTitle "Androgen receptor signaling" .

mapping:8aba0b0c-1d85-4ba8-8dab-dc1bd303b33a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-24T13:29:57.881637"^^xsd:dateTime ;
    dcterms:identifier "8aba0b0c-1d85-4ba8-8dab-dc1bd303b33a" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1283" ;
    ke-wp:keyEventName "Activation, TGF-beta pathway" ;
    ke-wp:pathwayId "WP560" ;
    ke-wp:pathwayTitle "TGF-beta receptor signaling" .

mapping:935eb43f-3226-4cf1-abce-d38cbe9f91c2 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T08:48:57.442432"^^xsd:dateTime ;
    dcterms:identifier "935eb43f-3226-4cf1-abce-d38cbe9f91c2" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 177" ;
    ke-wp:keyEventName "Increase, Mitochondrial dysfunction" ;
    ke-wp:pathwayId "WP623" ;
    ke-wp:pathwayTitle "Oxidative phosphorylation" .

mapping:93fce828-81cd-4305-b7ba-1b36ca0650f5 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:30.831620"^^xsd:dateTime ;
    dcterms:identifier "93fce828-81cd-4305-b7ba-1b36ca0650f5" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 926" ;
    ke-wp:keyEventName "Oxidation, Glutathione (To be considered with MIE)" ;
    ke-wp:pathwayId "WP100" ;
    ke-wp:pathwayTitle "Glutathione metabolism" .

mapping:9f064b32-a4ab-4c50-8f64-4db70aea6f7b a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-01-13 13:14:59"^^xsd:dateTime ;
    dcterms:identifier "9f064b32-a4ab-4c50-8f64-4db70aea6f7b" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 55" ;
    ke-wp:keyEventName "Increase, Cell injury/death" ;
    ke-wp:pathwayId "WP2507" ;
    ke-wp:pathwayTitle "Nanomaterial induced apoptosis" .

mapping:a5c102fa-7b60-48fa-90e3-b7b811e583af a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T11:59:09.512244"^^xsd:dateTime ;
    dcterms:identifier "a5c102fa-7b60-48fa-90e3-b7b811e583af" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1825" ;
    ke-wp:keyEventName "Increase, Cell death" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" .

mapping:a6638a2b-0e38-4d4f-9e09-89b36b530398 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:33.602913"^^xsd:dateTime ;
    dcterms:identifier "a6638a2b-0e38-4d4f-9e09-89b36b530398" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 40" ;
    ke-wp:keyEventName "Mitochondrial ATP production, decreased" ;
    ke-wp:pathwayId "WP391" ;
    ke-wp:pathwayTitle "Mitochondrial gene expression" .

mapping:a7c2e4cc-ef2d-4c74-8e4a-3b4dc8a3aa2a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:13.399987"^^xsd:dateTime ;
    dcterms:identifier "a7c2e4cc-ef2d-4c74-8e4a-3b4dc8a3aa2a" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 50" ;
    ke-wp:keyEventName "Increase, Ca++ (intracellular)" ;
    ke-wp:pathwayId "WP254" ;
    ke-wp:pathwayTitle "Apoptosis" .

mapping:b21ac548-dd63-480b-9199-7f9391587af8 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T11:59:13.592007"^^xsd:dateTime ;
    dcterms:identifier "b21ac548-dd63-480b-9199-7f9391587af8" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 149" ;
    ke-wp:keyEventName "Increase, Inflammation" ;
    ke-wp:pathwayId "WP530" ;
    ke-wp:pathwayTitle "Cytokines and inflammatory response" .

mapping:b53d61ea-d3d8-45ea-b44c-309247dc7d28 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13 05:47:13"^^xsd:dateTime ;
    dcterms:identifier "b53d61ea-d3d8-45ea-b44c-309247dc7d28" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 17" ;
    ke-wp:keyEventName "KE 17 - Altered gene expression, AHR nuclear translocator (ARNT)-dependent pathway" ;
    ke-wp:pathwayId "WP2882" ;
    ke-wp:pathwayTitle "Nuclear receptors meta-pathway" .

mapping:b66987de-ae63-418e-a2a2-1d7562174851 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-01T12:25:51.610626"^^xsd:dateTime ;
    dcterms:identifier "b66987de-ae63-418e-a2a2-1d7562174851" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 9" ;
    ke-wp:keyEventName "Activation, 5HT2c" ;
    ke-wp:pathwayId "WP5239" ;
    ke-wp:pathwayTitle "Lac-Phe pathway" .

mapping:b8eeaa97-12cc-466d-b735-2fdfb03d3e22 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13 05:42:58"^^xsd:dateTime ;
    dcterms:identifier "b8eeaa97-12cc-466d-b735-2fdfb03d3e22" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 25" ;
    ke-wp:keyEventName "KE 25 - Agonism, Androgen receptor" ;
    ke-wp:pathwayId "WP2263" ;
    ke-wp:pathwayTitle "Androgen receptor network in prostate cancer" .

mapping:bb7b4563-1c93-4822-a3dc-3f77b1f509e1 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:38.622413"^^xsd:dateTime ;
    dcterms:identifier "bb7b4563-1c93-4822-a3dc-3f77b1f509e1" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1104" ;
    ke-wp:keyEventName "Decreased, Prostaglandin F2alpha concentration, plasma" ;
    ke-wp:pathwayId "WP98" ;
    ke-wp:pathwayTitle "Prostaglandin synthesis and regulation" .

mapping:bbc8a46d-3b48-4b72-8845-a1fab1e4cc3a a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13 06:18:18"^^xsd:dateTime ;
    dcterms:identifier "bbc8a46d-3b48-4b72-8845-a1fab1e4cc3a" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 2336" ;
    ke-wp:keyEventName "Increase, SREBF1" ;
    ke-wp:pathwayId "WP22" ;
    ke-wp:pathwayTitle "IL9 signaling" .

mapping:c002a994-b638-4c79-bbf7-76a578f527a0 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13 06:13:34"^^xsd:dateTime ;
    dcterms:identifier "c002a994-b638-4c79-bbf7-76a578f527a0" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 2072" ;
    ke-wp:keyEventName "Increase, Mitochondrial swelling" ;
    ke-wp:pathwayId "WP5241" ;
    ke-wp:pathwayTitle "Mitochondrial beta-oxidation" .

mapping:c11425fd-d781-4f36-815d-d8931a5d5c8c a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-10-02 11:08:38"^^xsd:dateTime ;
    dcterms:identifier "c11425fd-d781-4f36-815d-d8931a5d5c8c" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 10" ;
    ke-wp:keyEventName "Acetylcholine accumulation in synapses" ;
    ke-wp:pathwayId "WP528" ;
    ke-wp:pathwayTitle "Acetylcholine synthesis" .

mapping:d03eb198-e060-4046-9349-038d809dcaea a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-10-01 16:38:58"^^xsd:dateTime ;
    dcterms:identifier "d03eb198-e060-4046-9349-038d809dcaea" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 79" ;
    ke-wp:keyEventName "Inhibition, Cyclooxygenase activity" ;
    ke-wp:pathwayId "WP4719" ;
    ke-wp:pathwayTitle "Eicosanoid metabolism via cyclooxygenases (COX)" .

mapping:d16cb071-1f02-4089-989b-939c1391612e a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2025-08-13 05:47:13"^^xsd:dateTime ;
    dcterms:identifier "d16cb071-1f02-4089-989b-939c1391612e" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 17" ;
    ke-wp:keyEventName "KE 17 - Altered gene expression, AHR nuclear translocator (ARNT)-dependent pathway" ;
    ke-wp:pathwayId "WP2289" ;
    ke-wp:pathwayTitle "Drug induction of bile acid pathway" .

mapping:d6d3f689-00ab-4f9a-8c49-e3a1e35a1547 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-03-03T08:48:33.834124"^^xsd:dateTime ;
    dcterms:identifier "d6d3f689-00ab-4f9a-8c49-e3a1e35a1547" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 281" ;
    ke-wp:keyEventName "Thyroxine (T4) in serum, Decreased" ;
    ke-wp:pathwayId "WP1981" ;
    ke-wp:pathwayTitle "Thyroxine (thyroid hormone) production" .

mapping:db828dc6-9737-4e63-ba87-c6d45ad4ae8d a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-25T12:29:07.474042"^^xsd:dateTime ;
    dcterms:identifier "db828dc6-9737-4e63-ba87-c6d45ad4ae8d" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 709" ;
    ke-wp:keyEventName "Increase, Cytotoxicity (renal tubular cell)" ;
    ke-wp:pathwayId "WP4864" ;
    ke-wp:pathwayTitle "Host-pathogen interaction of human coronaviruses - apoptosis" .

mapping:dc7b7289-517d-45dc-9f1f-88976fb11f35 a ke-wp:KeyEventPathwayMapping ;
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    dcterms:date "2026-02-18 08:08:41"^^xsd:dateTime ;
    dcterms:identifier "dc7b7289-517d-45dc-9f1f-88976fb11f35" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 1528" ;
    ke-wp:keyEventName "Fatty Acid Beta Oxidation, Decreased" ;
    ke-wp:pathwayId "WP143" ;
    ke-wp:pathwayTitle "Fatty acid beta-oxidation" .

mapping:e762a290-66f0-4db1-8f1a-8380420e9bde a ke-wp:KeyEventPathwayMapping ;
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    dcterms:date "2026-03-03T08:48:42.278147"^^xsd:dateTime ;
    dcterms:identifier "e762a290-66f0-4db1-8f1a-8380420e9bde" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1103" ;
    ke-wp:keyEventName "Inhibition, Cyclooxygenase 1 activity" ;
    ke-wp:pathwayId "WP4719" ;
    ke-wp:pathwayTitle "Eicosanoid metabolism via cyclooxygenases (COX)" .

mapping:ebe94629-c5aa-44a8-86fb-6da0f48ce9b6 a ke-wp:KeyEventPathwayMapping ;
    dcterms:creator "marvinm2" ;
    dcterms:date "2026-02-19 09:44:12"^^xsd:dateTime ;
    dcterms:identifier "ebe94629-c5aa-44a8-86fb-6da0f48ce9b6" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1632" ;
    ke-wp:keyEventName "Increase in reactive oxygen and nitrogen species (RONS)" ;
    ke-wp:pathwayId "WP5233" ;
    ke-wp:pathwayTitle "Arsenic metabolism and reactive oxygen species generation" .

mapping:ed25d939-b504-4377-8a00-a45f061c26ec a ke-wp:KeyEventPathwayMapping ;
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    dcterms:date "2026-02-11 11:29:39"^^xsd:dateTime ;
    dcterms:identifier "ed25d939-b504-4377-8a00-a45f061c26ec" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 188" ;
    ke-wp:keyEventName "Neuroinflammation" ;
    ke-wp:pathwayId "WP5485" ;
    ke-wp:pathwayTitle "Post-COVID neuroinflammation" .

mapping:edd06611-79dd-47ca-8de0-69b360072333 a ke-wp:KeyEventPathwayMapping ;
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    dcterms:date "2025-08-13 06:10:35"^^xsd:dateTime ;
    dcterms:identifier "edd06611-79dd-47ca-8de0-69b360072333" ;
    ke-wp:confidenceLevel "high" ;
    ke-wp:keyEventId "KE 654" ;
    ke-wp:keyEventName "KE 654 - Decreased testosterone by the fetal Leydig cells, Activation by other glucocorticoid receptor agonists" ;
    ke-wp:pathwayId "WP49" ;
    ke-wp:pathwayTitle "IL2 signaling" .

mapping:f0d767c3-ea71-40db-a6c1-865aafec9378 a ke-wp:KeyEventPathwayMapping ;
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    dcterms:date "2026-02-25T12:29:01.534945"^^xsd:dateTime ;
    dcterms:identifier "f0d767c3-ea71-40db-a6c1-865aafec9378" ;
    ke-wp:confidenceLevel "medium" ;
    ke-wp:keyEventId "KE 1096" ;
    ke-wp:keyEventName "Increased, blood uric acid concentration" ;
    ke-wp:pathwayId "WP497" ;
    ke-wp:pathwayTitle "Urea cycle and metabolism of amino groups" .