KE1392_Oxidative_Stress_R-HSA-9818027	NFE2L2 regulating anti-oxidant/detoxification enzymes	ATF4	BACH1	CHD6	CREBBP	EP300	GCLC	GCLM	GSR	GSTA1	GSTA3	HMOX1	MAFK	NFE2L2	NQO1	PRDX1	SLC7A11	SOD3	SRXN1	TXN	TXNRD1
KE1825_Increase_Cell_death_R-HSA-5633008	TP53 Regulates Transcription of Cell Death Genes	AIFM2	APAF1	ATM	BAX	BBC3	BCL2L14	BCL6	BID	BIRC5	BNIP3L	CASP1	CASP10	CASP2	CASP6	CHM	CRADD	CREBBP	FAS	IGFBP3	NDRG1	NLRC4	PERP	PIDD1	PMAIP1	PPP1R13B	PRELID1	PRELID3A	RABGGTA	RABGGTB	STEAP3	TMEM219	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TRIAP1	ZNF420
KE1194_Increase_DNA_damage_R-HSA-5693565	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	ABL1	ABRAXAS1	APBB1	ATM	BABAM1	BABAM2	BAP1	BARD1	BAZ1B	BRCA1	BRCC3	CHEK2	EYA1	EYA2	EYA3	EYA4	H2AX	H2BC1	H2BC11	H2BC12	H2BC12L	H2BC13	H2BC14	H2BC15	H2BC17	H2BC21	H2BC26	H2BC3	H2BC4	H2BC5	H2BC9	H3-4	H4C1	HERC2	KAT5	KDM4A	KDM4B	MAPK8	MDC1	MRE11	NBN	NSD2	PHF6	PIAS4	PPP5C	RAD50	RNF168	RNF8	RPS27A	SMARCA5	SUMO1	TP53	TP53BP1	UBA52	UBB	UBC	UBE2I	UBE2N	UBE2V2	UBXN1	UIMC1
KE177_Increase_Mitochondrial_dysfunction_R-HSA-204174	Regulation of pyruvate dehydrogenase (PDH) complex	DLAT	DLD	GSTZ1	PDHA1	PDHA2	PDHB	PDHX	PDK1	PDK2	PDK3	PDK4	PDP1	PDP2	PDPR	SIRT4
KE55_Increase_Cell_injury_death_R-HSA-5357769	Caspase activation via extrinsic apoptotic signalling pathway	APPL1	CASP3	CASP8	CASP9	CD14	CFLAR	DAPK1	DAPK2	DAPK3	DCC	FADD	FAS	FASLG	LY96	MAGED1	MC159L	ORF71	RIPK1	TICAM1	TICAM2	TLR4	TNFRSF10A	TNFRSF10B	TNFSF10	TRADD	TRAF2	UNC5A	UNC5B
KE55_Increase_Cell_injury_death_R-HSA-5357786	TNFR1-induced proapoptotic signaling	BIRC2	BIRC3	CASP8	CYLD	FADD	IKBKE	MIB2	OPTN	OTUD1	OTUD7B	RBCK1	RIPK1	RNF31	SHARPIN	SPATA2	TBK1	TNF	TNFAIP3	TNFRSF1A	TRADD	TRAF2	UL36	USP2	USP21	USP4	XIAP