KE177_Increase_Mitochondrial_dysfunction_R-HSA-204174	Regulation of pyruvate dehydrogenase (PDH) complex	DLAT	DLD	GSTZ1	PDHA1	PDHA2	PDHB	PDHX	PDK1	PDK2	PDK3	PDK4	PDP1	PDP2	PDPR	SIRT4
KE55_Increase_Cell_injury_death_R-HSA-5357769	Caspase activation via extrinsic apoptotic signalling pathway	APPL1	CASP3	CASP8	CASP9	CD14	CFLAR	DAPK1	DAPK2	DAPK3	DCC	FADD	FAS	FASLG	LY96	MAGED1	MC159L	ORF71	RIPK1	TICAM1	TICAM2	TLR4	TNFRSF10A	TNFRSF10B	TNFSF10	TRADD	TRAF2	UNC5A	UNC5B
KE55_Increase_Cell_injury_death_R-HSA-5357786	TNFR1-induced proapoptotic signaling	BIRC2	BIRC3	CASP8	CYLD	FADD	IKBKE	MIB2	OPTN	OTUD1	OTUD7B	RBCK1	RIPK1	RNF31	SHARPIN	SPATA2	TBK1	TNF	TNFAIP3	TNFRSF1A	TRADD	TRAF2	UL36	USP2	USP21	USP4	XIAP