# molAOP Builder GMT export
# resource: KE-GO
# export-revision: 2dddd425b396a190
# source-fingerprint: 355:64670d5e1c509203017f23e4291bb494|go_bp_gene_annotations.json:2029010:1785755892173618639;go_bp_gene_annotations_propagated.json:8685587:1785755888659768320;go_bp_hierarchy.json:12723326:1785755889895509678;go_mf_gene_annotations.json:1323163:1785833670554748481;go_mf_gene_annotations_propagated.json:2539186:1785833671659605085;go_mf_hierarchy.json:3675724:1785833672013980155
# confidence: all tiers
# generated: 2026-09-05T04:01:54+00:00
# Lines beginning with # are provenance, not gene sets.
KE195_Inhibition_NMDARs_GO:2000310	regulation of NMDA receptor activity	CRH	CRHBP	DAPK1	OPRM1
KE52_Decreased_Calcium_influx_GO:0070509	calcium ion import	ATP2A1	ATP2B4	CACNA1A	CACNA1B	CACNA1C	CACNA1D	CACNA1E	CACNA1F	CACNA1G	CACNA1H	CACNA1I	CACNA1S	CACNA2D1	CACNB2	CALHM2	GCK	MCUR1	MICU1	NALF1	NALF2	SLC24A1	SLC24A2	SLC24A4	SLC24A5	SLC30A1	SLC8A1	SLC8A3	TRPC4	TRPM1	TRPM2	TRPV1	TRPV2	TRPV3	TRPV4	TRPV5	TRPV6
KE381_Reduced_levels_of_BDNF_GO:0032898	neurotrophin production	FURIN	PCSK6
KE382_Aberrant_Dendritic_morphology_GO:0048813	dendrite morphogenesis	ABITRAM	ARC	BTBD3	CDC42	CELSR2	CHRNA7	CTNNA2	CTNND2	DCDC2	DIP2A	DLG4	DOCK10	DVL1	EPHB1	EPHB2	EPHB3	FARP1	IGF2BP1	KLF7	LRP4	LRP8	MAP2	MAP6	MAPK8IP2	MEF2A	MINK1	NRP1	PAK3	PHACTR1	PICALM	PTEN	PTN	SDC2	SEMA3A	SHANK1	SHANK3	SULT4A1	TAOK2	TMEM106B	TRAK2	VLDLR	WASL	WNT7A	ZNF365
KE385_Decrease_of_synaptogenesis_GO:0007416	synapse assembly	ACHE	ADD2	ADGRF1	ADGRL2	ADGRL3	AKAP5	BDNF	BSN	C1QL2	C1QL3	CBLN4	CDH1	CDH2	CDK5	CLSTN2	CNTN5	CRK	CRKL	CSMD2	DAG1	DBNL	DNER	DNM3	DRD1	DRD2	DSCAM	DVL1	EFNB2	EGFLAM	EPHB2	ERBB4	FARP1	FBXO45	FGF13	FLRT3	FZD1	FZD5	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB2	GABRB3	GABRE	GABRG1	GABRG2	GABRG3	GPHN	GPM6A	GRIA1	GRID2	HAPLN4	IL1RAPL1	KIRREL3	LGI2	LRP4	LRRC4	MAP1B	MYCBP2	NLGN1	NLGN2	NLGN3	NLGN4X	NLGN4Y	NPAS4	NPTX1	NRCAM	NRG3	NRXN1	NRXN2	NRXN3	NTNG2	NTRK3	PCDH17	PCDHB10	PCDHB11	PCDHB13	PCDHB14	PCDHB16	PCDHB2	PCDHB3	PCDHB4	PCDHB5	PCDHB6	PCDHB9	PCLO	PLXNA1	PLXNA2	PLXNA3	PLXNA4	PLXNB1	PLXNB2	PLXNB3	PLXNC1	PLXND1	POU4F1	PTEN	PTPRD	RAB29	RELN	RYK	SDK1	SDK2	SHANK2	SHANK3	SKP1	SLITRK1	SLITRK6	SPOCK2	SRGAP2	SRGAP2C	VSIG10	WNT3A	WNT5A	WNT7A	ZDHHC12	ZDHHC2
KE386_Decrease_of_neuronal_network_function_GO:0007268	chemical synaptic transmission	ACHE	ACP1	ADORA1	ADORA2A	AGRN	AKAP5	AKAP9	AKT1	AMPH	ANXA9	AP2B1	APBA1	APBA2	APBA3	APOE	ARRB2	ATXN3	BEGAIN	BEST1	BRSK1	BSN	CACNA1A	CACNA1B	CACNA1E	CACNB1	CACNB2	CACNB3	CACNB4	CADPS	CADPS2	CARTPT	CBLN1	CBLN2	CDK5	CEP89	CHAT	CHRDL1	CHRFAM7A	CHRM1	CHRM2	CHRM3	CHRM4	CHRM5	CHRNA1	CHRNA10	CHRNA2	CHRNA3	CHRNA4	CHRNA5	CHRNA6	CHRNA7	CHRNA9	CHRNB1	CHRNB2	CHRNB3	CHRNB4	CHRND	CHRNE	CHRNG	CNIH2	CNIH3	CNP	COLQ	CORT	CPLX1	CPLX2	CPLX3	CPLX4	CRH	CRHBP	DBH	DLG1	DLG2	DLG3	DLG4	DLGAP1	DLGAP2	DNAJC5	DOC2A	DOC2B	DRD1	DRD2	DRD3	DRD4	DRD5	DTNA	DVL1	EEA1	EFR3A	ELFN1	ELFN2	ERC2	EXOC4	EZH2	FCHSD1	FCHSD2	GABARAP	GABBR1	GABBR2	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB1	GABRB2	GABRB3	GABRD	GABRE	GABRG1	GABRG2	GABRG3	GABRP	GABRQ	GABRR1	GABRR2	GABRR3	GAD1	GAD2	GALR3	GIPC1	GLRA1	GLRA2	GLRA3	GLRB	GPR176	GRIA1	GRIA2	GRIA3	GRIA4	GRID1	GRID2	GRIK1	GRIK2	GRIK3	GRIK4	GRIK5	GRIN1	GRIN2A	GRIN2B	GRIN2C	GRIN2D	GRIN3A	GRIN3B	GRM1	GRM2	GRM3	GRM4	GRM5	GRM6	GRM7	GSK3A	GSK3B	HAP1	HAPLN4	HCRT	HCRTR1	HCRTR2	HOMER1	HRH1	HRH2	HRH3	HRH4	HTR1A	HTR1B	HTR1D	HTR1E	HTR1F	HTR2A	HTR2B	HTR2C	HTR3A	HTR3B	HTR3C	HTR3D	HTR3E	HTR4	HTR5A	HTR6	HTR7	INSYN1	INSYN2A	KCNC4	KCND2	KCND3	KCNIP1	KCNIP2	KCNK2	KCNK3	KCNMB1	KCNMB4	KCNN1	KCNQ2	KCNQ3	KIF1B	KIF5A	LIN7A	LIN7B	LIN7C	LPAR3	LRP6	LRP8	LRRK2	MAPK1	MBP	MEF2C	MET	MINK1	MPP2	MPZ	MTNR1B	MYCBPAP	NAPA	NAPB	NLGN1	NLGN3	NOTCH1	NPAS4	NPBWR1	NPFF	NPR2	NPTX1	NPTX2	NPY	NPY5R	NQO1	NR3C1	NRXN1	NRXN2	NSG1	NTSR1	OMP	OPRK1	OPRL1	OTOF	P2RX1	P2RX2	P2RX3	P2RX4	P2RX5	P2RX6	P2RX7	PAFAH1B1	PCDH8	PCDHB10	PCDHB11	PCDHB13	PCDHB14	PCDHB16	PCDHB2	PCDHB3	PCDHB4	PCDHB5	PCDHB6	PCDHB9	PCLO	PDE7B	PDLIM4	PDYN	PDZD11	PENK	PIP5K1C	PLP1	PMCH	PMCHL1	PMCHL2	PMP22	PNOC	PPFIA3	PRKAR1A	PRKAR1B	PRKAR2A	PRKAR2B	PRKCG	PRRT2	PTCHD1	PTEN	PTPRN2	PVALB	RAB3A	RAB3GAP1	RAPSN	RASD2	RIC3	RIMBP2	RIMS1	RIMS2	RIMS3	RIT2	RPH3A	RPH3AL	RPS6KA1	RPS6KA2	RPS6KA3	SCN2B	SCRIB	SDCBP	SEPTIN5	SHISA6	SLC12A4	SLC12A5	SLC12A6	SLC12A7	SLC17A6	SLC17A7	SLC17A8	SLC18A2	SLC18A3	SLC1A1	SLC1A2	SLC1A3	SLC1A4	SLC1A6	SLC1A7	SLC29A1	SLC32A1	SLC5A7	SLC6A1	SLC6A2	SLC6A3	SLC6A5	SNAP23	SNAP25	SNAP29	SNAP47	SNAPIN	SNCA	SNCB	SNCG	SNPH	SPG11	SSH1	SST	STAC3	STX11	STX19	STX1A	STX1B	STX2	STXBP1	STXBP2	STXBP3	SV2A	SV2B	SV2C	SYN1	SYN2	SYN3	SYNJ1	SYPL1	SYT1	SYT10	SYT11	SYT12	SYT13	SYT2	SYT3	SYT4	SYT5	SYT6	SYT7	SYT8	SYT9	TAC1	TH	TRPV1	UNC119	UNC13A	UNC13B	UNC13C	UTS2	VAMP1	VAMP2	VPS54
KE341_Impairment_Learning_and_memory_GO:0007611	learning or memory	ABCA7	ABCC8	ABL1	ACSS2	ADCY3	ADCY8	ADNP	AGER	AMFR	APOE	APP	ARC	ATAD1	ATP8A1	ATXN1	ATXN1L	B2M	BCHE	BGLAP	BRSK1	CALB1	CAMK2N1	CAMK4	CARTPT	CASP3	CCL11	CEBPB	CHRNA7	CHRNB2	CIC	CLDN5	CLN3	CLSTN2	CNTNAP2	CPEB3	CREB1	CRH	CRHBP	CUX2	DCANP1	DEAF1	DKK1	DLG4	DRD1	DRD2	DRD3	EGFR	EGR1	EIF2AK4	EIF4A3	EIF4EBP2	EN1	EP300	EPHB2	FEN1	FGF13	FOS	FOXB1	FOXO6	FYN	GALR2	GALR3	GATM	GHSR	GIT1	GLP1R	GPI	GPR88	GPRASP3	GRIA1	GRIN1	GRIN2A	GRIN2B	GRM5	GRPR	HTR2A	HTT	INSR	JPH3	KAT2A	KAT2B	KCNK2	KCNK4	KIT	KLK8	LCN2	LDLR	LGMN	LILRB2	LRRN4	MAP1A	MAPK1	MAPK8IP2	MAPT	MDK	MECP2	MEF2C	MME	MUSK	NDRG4	NEDD9	NETO1	NEUROG1	NF1	NFATC4	NLGN3	NLGN4X	NLGN4Y	NOG	NPAS4	NRGN	NRXN1	NRXN2	NRXN3	NTF4	NTRK1	NTRK2	NTSR1	OPRK1	OXT	PAFAH1B1	PGRMC1	PIAS1	PICALM	PJA2	PLCB1	PLK2	PLN	PPP1R9B	PPP3CB	PRKCA	PRKCG	PRNP	PSEN1	PTEN	PTN	PTPRZ1	RAG1	RAPGEF3	RASGRF1	RELN	RGS14	S100B	SCN2A	SERPINF1	SGK1	SHANK1	SHANK2	SHANK3	SHISA7	SIGMAR1	SLC1A1	SLC2A4	SLC6A1	SLC6A4	SLC8A2	SLC8A3	SRF	STRA6	SYNJ1	SYT11	SYT4	TAC1	TACR1	TACR2	TACR3	TAFA2	TH	TIFAB	TLR2	TREM2	TSC1	TTBK1	TUBA1A	UCN	VLDLR	YTHDF1
KE115_Increase_FA_Influx_GO:2000191	regulation of fatty acid transport	ACSL1	ACSL5	AKT1	AKT2	AVPR1B	CYP4A11	CYP4F2	EDN1	EPRS1	FABP3	FIS1	IL1B	IRS2	MIF	NTSR1	OXT	P2RX4	PLA2G10	PLA2R1	PPARA	REPIN1	SYK	THBS1	TNFRSF11A	TNFSF11
KE228_peroxisome_proliferator_activated_receptor_promoter_demethylation_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE898_Disruption_Lysosome_GO:1903008	organelle disassembly	ABCE1	AFG2B	ANKZF1	ASCC2	ASCC3	AURKA	CDK1	CDK5RAP3	CUL2	DDRGK1	DENR	DYRK3	EIF2D	EIF4E2	ELAC1	FAF2	GBF1	GCN1	GFM2	GIGYF2	GOLGA2	HBS1L	HDAC6	KAT5	KIF19	KIF5B	KIF9	KLC1	KLHDC10	LTN1	MAP4	MCTS1	MRPL58	MRRF	MTIF2	MTIF3	MTRES1	MTRFR	NEDD9	NEMF	NPLOC4	PELO	PLAAT1	PLAAT3	PLIN2	PLIN3	PLK3	PNPLA2	PRKAA1	PRKAA2	PTRH1	RACK1	RCHY1	RNF10	RNF14	RNF25	RRP7A	SAYSD1	SKIC2	SKIC3	SKIC8	SPAST	STX5	TCF25	TRIM21	TRIP4	TRNT1	UFD1	UFL1	UFSP2	USP10	VCP	VRK1	ZFAND1	ZNF598
KE1115_Increase_Reactive_oxygen_species_GO:1903409	reactive oxygen species biosynthetic process	ACOX1	CYBA	DUOX1	DUOX2	DUOXA1	DUOXA2	GBF1	INAVA	MAOB	NCF1	NOX4	SOD1	SOD2	TP53I3
KE1492_Tissue_resident_cell_activation_GO:0002263	cell activation involved in immune response	ANXA3	APP	BATF	BTK	C17orf99	CBL	CCL3	CCR6	CD180	CD19	CD1C	CD244	CD40LG	CD74	CDH17	CHGA	CLNK	CORO1A	CPLX2	CX3CR1	DLL1	DNASE1	DNASE1L3	DOCK10	DOCK11	DOCK2	DYSF	EIF2AK4	ENPP3	ENTPD7	EOMES	EXOSC3	EXOSC6	F2RL1	FCER1A	FCER1G	FCGR2B	FCGR3A	GAPT	GATA3	GBF1	GNAI1	GNAQ	GPR15LG	GPR183	GRN	GRP	HAVCR2	HMGB1	HSPD1	ICAM1	IFI35	IFNA10	IFNA14	IFNA16	IFNA17	IFNA2	IFNA21	IFNA4	IFNA5	IFNA6	IFNA7	IFNA8	IFNB1	IFNE	IFNG	IFNK	IFNW1	IL10	IL12B	IL18	IL18R1	IL18RAP	IL1RAP	IL2	IL21	IL33	IL6	IL6R	IL6ST	IRF4	IRF8	ITGAL	JAK1	JMJD1C	KARS1	KIT	KLRF2	KMT2A	LAT	LAT2	LBP	LCP1	LEF1	LFNG	LIG4	LILRA2	LILRB1	LRP1	LY9	LYN	MDK	MEN1	MFNG	MILR1	MRGPRX2	MSH2	MSH6	MTOR	MYB	NBN	NFKBIZ	NKG7	NMI	NOTCH2	NR4A3	PCYT1A	PHF14	PIK3CD	PIK3CG	PLA2G3	PLCG2	PLXNA1	POU2AF1	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB10	PSMB2	PSMB3	PSMB4	PSMB8	PSMB9	PTGDR	PTGDS	PTK2B	PYCARD	RAB44	RAG2	RNF168	RNF8	RORA	RORC	S100A13	SANBR	SBNO2	SCN11A	SEMA4A	SEMA6D	SH2D1B	SLAMF1	SLAMF6	SLC11A1	SLC18A2	SNAP23	SOCS3	SPI1	SPN	ST3GAL1	STAT3	STAT4	STXBP2	STXBP3	SYK	TBX21	TCIM	TMEM98	TNF	TNFSF18	TREM2	TYROBP	VAMP2	VAMP7
KE1493_Increased_Pro_inflammatory_mediators_GO:0002526	acute inflammatory response	ACVR1	AHSG	ANO6	APCS	APOL2	ASS1	C2CD4A	C2CD4B	CD163	CD6	CEBPB	CRP	CTNNBIP1	ELANE	EPO	F12	F2	F3	F8	FCER1A	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FN1	GATA3	HP	IGHG1	IL10RB	IL1A	IL1B	IL22	IL22RA1	IL6	IL6R	INS	ITIH4	KLKB1	LBP	LCN2	MBL2	MRGPRX1	NLRP6	NPFF	ORM1	ORM2	PLSCR1	REG3A	REG3G	SAA1	SAA2	SAA4	SCN11A	SERPINA1	SERPINA3	SERPINF2	SIGIRR	STAT3	TFRC	TNFSF4	VNN1
KE10_Acetylcholine_accumulation_in_synapses_GO:0001507	acetylcholine catabolic process in synaptic cleft	ACHE	COLQ
KE10_Acetylcholine_accumulation_in_synapses_GO:0061526	acetylcholine secretion	SLC44A4
KE50_Increase_Ca_intracellular_GO:0006874	intracellular calcium ion homeostasis	ADCY8	ADORA1	AFG3L2	ANK2	ANXA6	ASPH	ATP13A1	ATP13A2	ATP13A3	ATP13A4	ATP13A5	ATP1B1	ATP2A1	ATP2A2	ATP2A3	ATP2B1	ATP2B2	ATP2B3	ATP2B4	ATP2C1	ATP2C2	BAK1	BAX	BCL2	BNIP3	BOK	C19orf12	CACNB2	CACNB4	CALB1	CALB2	CALCA	CALCB	CALR	CAMK2D	CARTPT	CASQ2	CASR	CAV1	CAV2	CAV3	CCDC47	CCL1	CCL11	CCL13	CCL14	CCL15	CCL19	CCL23	CCL3	CCL5	CCL7	CCL8	CCR1	CCR2	CD40	CDH23	CDH5	CHERP	CHRNA7	CLCC1	CLN3	CNGB1	CNR1	CSRP3	CTRC	CXCL12	DHRS7C	DMPK	DMTN	DRD3	DRD4	DRD5	EDN1	EDN2	EDN3	EDNRA	ELANE	ERC2	F2	FATE1	FZD9	GCM2	GPER1	GRID2IP	GRM1	GRM5	HCRTR1	HCRTR2	HERPUD1	HRC	HTR2A	HTR2B	HTR2C	ITPR1	KCNH1	KCNK16	KCTD17	LETM1	MAIP1	MCU	MCUB	MCUR1	MICU1	MICU2	MICU3	MYH7B	NPPC	NPTN	NPY	OSBPL2	P2RX1	P2RY1	PACS2	PDZD8	PKHD1	PLN	PML	PSEN1	PTH	PTH1R	RAP1GDS1	RGN	RMDN3	RYR1	RYR2	RYR3	SELENOK	SLC10A7	SLC24A1	SLC24A2	SLC24A3	SLC24A4	SLC24A5	SLC25A23	SLC25A27	SLC30A1	SLC35G1	SLC8A1	SLC8A2	SLC8A3	SLC8B1	SMDT1	SPPL2C	STC1	STC2	STIM1	STIM2	STOML2	SV2B	TGM2	THADA	TMCO1	TMEM165	TMEM178A	TMEM203	TMEM64	TNNI3	TPCN2	TPT1	TRDN	TRPA1	TRPC1	TRPC3	TRPC4	TRPC5	TRPC6	TRPC7	TRPV4	TSPOAP1	TUNAR	VAPB	VPS54	WFS1	WNT5A	YWHAE
KE357_Cholestasis_Pathology_GO:0032782	bile acid secretion	ABCB4	CASR	NHERF1	SLC51A	SLC51B	UGT1A3
KE1391_Activation_of_Cyp2E1_GO:0006805	xenobiotic metabolic process	AADAC	ABCB1	ABCB11	ABCC1	ABCC2	ABCC3	ABCC4	ABCC5	ABHD10	ACAA1	ACSL1	ACSM1	ACSM2B	ADA	AHR	AHRR	AKR1C1	ALDH2	ALDH3A1	AOC2	AOX1	ARNT	ARNT2	AS3MT	BCHE	BPHL	CAD	CBR1	CBR3	CES2	CES3	CMBL	CRYZ	CYB5B	CYP1A1	CYP1A2	CYP1B1	CYP26A1	CYP26B1	CYP2A13	CYP2A6	CYP2A7	CYP2B6	CYP2C18	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP2D7	CYP2E1	CYP2F1	CYP2J2	CYP2R1	CYP2S1	CYP2U1	CYP2W1	CYP3A4	CYP3A5	CYP3A7	CYP46A1	CYP4F12	CYP4F2	DPYD	EPHX1	FMO2	FMO4	FMO5	GLYAT	GRIN1	GSTA1	GSTA2	GSTA3	GSTA4	GSTA5	GSTM1	GSTM2	GSTM3	GSTM4	GSTO1	GSTO2	GSTP1	GUK1	HEMK2	HNF4A	NAT1	NAT2	NOS1	NQO1	NR1I2	NUDT15	PRKCE	RBBP9	RORA	RORC	S100A12	SLC22A1	SLC22A7	SLC28A2	SLC28A3	SLC29A1	SLC29A3	SLCO1A2	SLCO1B1	SLCO1B3	SLCO2B1	SMOX	SULT1A1	SULT1A2	SULT1A3	SULT1B1	SULT1C3	SULT1C4	SULT2A1	TPMT	UGT1A1	UGT1A10	UGT1A3	UGT1A6	UGT1A7	UGT1A8	UGT1A9	UGT2A1	UGT2A2	UGT2A3	UGT2B11	UGT2B15	UGT2B17	UGT2B4	UGT2B7	UPP2	VKORC1
KE105_Inhibition_Mitochondrial_Electron_Transport_Chain_Complexes_GO:0022904	respiratory electron transport chain	AIFM2	C2orf69	COX4I1	COX4I2	COX5A	COX5B	COX6A1	COX6A2	COX6B1	COX6C	COX7A1	COX7A2	COX7A2L	COX7A2P2	COX7B	COX7B2	COX7C	COX8A	COX8C	COXFA4	CYC1	CYCS	DGUOK	ETFA	ETFB	ETFDH	FOXRED1	HCCS	HIGD1A	HIGD2A	MT-CO1	MT-CO2	MT-CO3	MT-CYB	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	NDUFA1	NDUFA10	NDUFA11	NDUFA12	NDUFA13	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFAF1	NDUFB1	NDUFB10	NDUFB11	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFC2-KCTD14	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3	PINK1	PLEC	PPARGC1A	PUM2	SDHA	SDHAF2	SDHB	SDHC	SDHD	SLC25A51	TTC19	UQCC3	UQCC4	UQCR10	UQCR11	UQCRB	UQCRC1	UQCRC2	UQCRFS1	UQCRFS1P1	UQCRH	UQCRHL	UQCRQ	VPS54
KE178_Mitochondrial_electron_transport_chain_disrupted_GO:0022904	respiratory electron transport chain	AIFM2	C2orf69	COX4I1	COX4I2	COX5A	COX5B	COX6A1	COX6A2	COX6B1	COX6C	COX7A1	COX7A2	COX7A2L	COX7A2P2	COX7B	COX7B2	COX7C	COX8A	COX8C	COXFA4	CYC1	CYCS	DGUOK	ETFA	ETFB	ETFDH	FOXRED1	HCCS	HIGD1A	HIGD2A	MT-CO1	MT-CO2	MT-CO3	MT-CYB	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	NDUFA1	NDUFA10	NDUFA11	NDUFA12	NDUFA13	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFAF1	NDUFB1	NDUFB10	NDUFB11	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFC2-KCTD14	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3	PINK1	PLEC	PPARGC1A	PUM2	SDHA	SDHAF2	SDHB	SDHC	SDHD	SLC25A51	TTC19	UQCC3	UQCC4	UQCR10	UQCR11	UQCRB	UQCRC1	UQCRC2	UQCRFS1	UQCRFS1P1	UQCRH	UQCRHL	UQCRQ	VPS54
KE193_Decreased_Nitric_Oxide_GO:0046209	nitric oxide metabolic process	AKT1	ARG2	CAV1	CPS1	CYB5B	CYB5R3	CYGB	CYP1A1	CYP1B1	DDAH1	GCH1	HSP90AA1	MTARC1	MTARC2	NOS1	NOS1AP	NOS2	NOS3	NOSIP	NQO1	POR	PPARA	SLC7A6	SPR	TLR6	ZDHHC21
KE201_Binding_of_antagonist_NMDA_receptors_GO:0098989	NMDA selective glutamate receptor signaling pathway	APP	CAPN1	DLG4	DORIP1	MEF2C	NLGN1
KE327_Accumulation_Fatty_acid_GO:0006631	fatty acid metabolic process	AACS	AASDH	ABCB11	ABCD1	ABCD2	ABCD3	ABCD4	ABHD1	ABHD12	ABHD2	ABHD3	ABHD5	ABHD6	ACAA1	ACAA2	ACACA	ACACB	ACAD10	ACAD11	ACAD9	ACADL	ACADM	ACADS	ACADSB	ACADVL	ACAT1	ACAT2	ACBD4	ACBD5	ACBD7	ACLY	ACOT1	ACOT11	ACOT12	ACOT2	ACOT4	ACOT6	ACOT7	ACOT7L	ACOT8	ACOT9	ACOX1	ACOX2	ACOX3	ACOXL	ACSBG1	ACSBG2	ACSF2	ACSF3	ACSL1	ACSL3	ACSL4	ACSL5	ACSL6	ACSM1	ACSM2A	ACSM2B	ACSM3	ACSM4	ACSM5	ACSM6	ACSS1	ACSS2	ADH4	ADH5	ADH7	ADIPOQ	ADIPOR1	ADIPOR2	ADTRP	AIG1	AKR1B1	AKR1C1	AKR1C2	AKR1C3	AKR1C4	ALDH3A2	ALKBH7	ALOX12	ALOX12B	ALOX15	ALOX15B	ALOX5	ALOXE3	AMACR	ANGPTL3	AOAH	ASAH1	ASAH2	AUH	AWAT1	BAAT	BDH2	BRCA1	C3	CBR1	CBR4	CD36	CD74	CES1	CES1P1	CES2	CPT1A	CPT1B	CPT1C	CPT2	CRAT	CROT	CRYL1	CTHRC1	CYGB	CYP1A1	CYP1A2	CYP1B1	CYP2A13	CYP2A6	CYP2A7	CYP2B6	CYP2C18	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP2D7	CYP2E1	CYP2F1	CYP2J2	CYP2S1	CYP2U1	CYP3A4	CYP4A11	CYP4A22	CYP4B1	CYP4F11	CYP4F12	CYP4F2	CYP4F3	CYP4F8	CYP4V2	CYP4Z1	DAGLA	DAGLB	DBI	DECR1	DECR2	DEGS1	ECH1	ECHDC1	ECHDC2	ECHDC3	ECHS1	ECI1	ECI2	EHHADH	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	EPHX1	ETFA	ETFB	ETFDH	FA2H	FAAH	FAAH2	FABP2	FABP3	FADS1	FADS2	FADS2B	FADS3	FADS6	FASN	GCDH	GGT1	GGT5	GLYATL2	GPX1	GPX4	GSTA1	GSTM1	GSTM2	GSTM4	GSTP1	HACD1	HACD2	HACD3	HACD4	HACL1	HACL2	HADH	HADHA	HADHB	HAO1	HAO2	HPGD	HPGDS	HSD17B10	HSD17B12	HSD17B4	HSD17B8	HTD2	IVD	LEP	LIAS	LIPC	LIPG	LPIN1	LPIN2	LPIN3	LPL	LTC4S	LYPLA1	LYPLA2	MBLAC2	MCAT	MCEE	MECR	MGLL	MGST3	MIF	MLYCD	MORC2	MSMO1	MTLN	NAAA	NDUFAB1	NUDT19	NUDT7	NUDT8	OLAH	OXSM	PCCA	PCCB	PECR	PEDS1	PER2	PEX13	PEX2	PHYH	PLA2G10	PLA2G15	PLA2G1B	PLA2G2F	PLA2G4A	PLA2G4B	PLA2G4C	PLA2G4D	PLA2G5	PM20D1	PNLIP	PNLIPRP1	PNLIPRP2	PNLIPRP3	PNPLA3	PNPLA8	POR	PPARA	PPARD	PPARG	PPARGC1A	PRKAA1	PRKAA2	PRKAB1	PRKAB2	PRKAG1	PRKAG2	PRKAG3	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGR1	PTGR2	PTGR3	PTGS1	PTGS2	SCD	SCD5	SCP2	SGPL1	SIGMAR1	SLC25A17	SLC27A1	SLC27A2	SLC27A3	SLC27A4	SLC27A5	SLC27A6	TBXAS1	TECR	TECRL	THEM4	THEM5	TMEM135	TNFRSF1A	UGT1A8	XBP1
KE327_Accumulation_Fatty_acid_GO:0015908	fatty acid transport	ABCC4	ABCD1	ABCD2	ABCD3	ABCD4	ACE	ACSL1	ACSL3	APOE	BDKRB2	CD36	CPT1A	CPT1B	CPT2	CRABP1	CRABP2	DRD2	DRD3	DRD4	FABP1	FABP12	FABP2	FABP3	FABP4	FABP5	FABP5P3	FABP6	FABP7	FABP9	GOT2	LEP	LYN	LYPLA1	MFSD2A	NMB	NMUR2	NOS2	OC90	PLA2G10	PLA2G12A	PLA2G12B	PLA2G1B	PLA2G2A	PLA2G2C	PLA2G2D	PLA2G2E	PLA2G2F	PLA2G3	PLA2G4A	PLA2G5	PMP2	PNPLA8	PPARD	PPARG	PROCA1	RBP1	RBP2	RBP5	RBP7	RPS6KB1	SLC22A1	SLC22A11	SLC22A2	SLC22A6	SLC22A7	SLC22A8	SLC22A9	SLC25A17	SLC25A20	SLC27A1	SLC27A2	SLC27A3	SLC27A4	SLC27A5	SLC27A6	SLC2A1	SLC43A3	SLC5A8	SLCO1B1	SLCO2A1	SLCO2B1	SLCO3A1	SLCO4A1	SPX	THRSP	UCP2
KE345_N_A_Liver_Steatosis_GO:0019915	lipid storage	ADIG	ANGPTL3	APOC4	APOE	AUP1	BSCL2	CAV1	CD36	CDS1	CDS2	CIDEA	CIDEB	CIDEC	CRY1	CRY2	DAB2IP	DGAT1	DGAT2	FFAR2	FITM1	FITM2	LDAF1	LDAH	LRAT	MOSPD2	NRIP1	PISD	PLA2G4C	PLIN2	PLIN3	PLIN5	PNPLA2	RAB40C	RNF213	SMIM22	SOAT1	SQLE	STARD4	ZFYVE1
KE637_impaired_Learning_and_memory_GO:0007611	learning or memory	ABCA7	ABCC8	ABL1	ACSS2	ADCY3	ADCY8	ADNP	AGER	AMFR	APOE	APP	ARC	ATAD1	ATP8A1	ATXN1	ATXN1L	B2M	BCHE	BGLAP	BRSK1	CALB1	CAMK2N1	CAMK4	CARTPT	CASP3	CCL11	CEBPB	CHRNA7	CHRNB2	CIC	CLDN5	CLN3	CLSTN2	CNTNAP2	CPEB3	CREB1	CRH	CRHBP	CUX2	DCANP1	DEAF1	DKK1	DLG4	DRD1	DRD2	DRD3	EGFR	EGR1	EIF2AK4	EIF4A3	EIF4EBP2	EN1	EP300	EPHB2	FEN1	FGF13	FOS	FOXB1	FOXO6	FYN	GALR2	GALR3	GATM	GHSR	GIT1	GLP1R	GPI	GPR88	GPRASP3	GRIA1	GRIN1	GRIN2A	GRIN2B	GRM5	GRPR	HTR2A	HTT	INSR	JPH3	KAT2A	KAT2B	KCNK2	KCNK4	KIT	KLK8	LCN2	LDLR	LGMN	LILRB2	LRRN4	MAP1A	MAPK1	MAPK8IP2	MAPT	MDK	MECP2	MEF2C	MME	MUSK	NDRG4	NEDD9	NETO1	NEUROG1	NF1	NFATC4	NLGN3	NLGN4X	NLGN4Y	NOG	NPAS4	NRGN	NRXN1	NRXN2	NRXN3	NTF4	NTRK1	NTRK2	NTSR1	OPRK1	OXT	PAFAH1B1	PGRMC1	PIAS1	PICALM	PJA2	PLCB1	PLK2	PLN	PPP1R9B	PPP3CB	PRKCA	PRKCG	PRNP	PSEN1	PTEN	PTN	PTPRZ1	RAG1	RAPGEF3	RASGRF1	RELN	RGS14	S100B	SCN2A	SERPINF1	SGK1	SHANK1	SHANK2	SHANK3	SHISA7	SIGMAR1	SLC1A1	SLC2A4	SLC6A1	SLC6A4	SLC8A2	SLC8A3	SRF	STRA6	SYNJ1	SYT11	SYT4	TAC1	TACR1	TACR2	TACR3	TAFA2	TH	TIFAB	TLR2	TREM2	TSC1	TTBK1	TUBA1A	UCN	VLDLR	YTHDF1
KE708_Increased_Accumulation_of_alpha2u_microglobulin_proximal_tubular_epithelium_GO:0097017	renal protein absorption	AMN	EDNRA	EDNRB	GSN
KE771_Decrease_Serum_thyroid_hormone_T4_T3_GO:0042403	thyroid hormone metabolic process	CPQ	CRYM	CTSB	CTSK	DIO1	DIO2	DIO3	DUOX1	DUOX2	FOXE1	IYD	SLC16A2	SLC26A7	SLC5A5	SULT1A1	SULT1A3	SULT1A4	SULT1B1	SULT2A1	TG	TPO
KE829_Damage_Lipid_bilayer_GO:0061024	membrane organization	A4GALT	AAK1	ABCA1	ABCA12	ABCA2	ABCA3	ABCA4	ABCA7	ABCB1	ABCB4	ABCC1	ABCD1	ABCD2	ABCG1	ACE2	ADGRB1	AGK	AGRN	AIF1	AKAP8L	ALKBH4	ANK2	ANK3	ANKFY1	ANKLE2	ANO3	ANO4	ANO5	ANO6	ANO7	ANO9	ANXA2	ANXA7	AP2M1	AP3B2	AP3D1	AP3M2	AP3S1	AP3S2	APOE	APOO	APOOL	ARF1	ARFGAP2	ARFGAP3	ARHGAP12	ARHGAP25	ARL6IP1	ARL8B	ARV1	ATG2A	ATG2B	ATG9A	ATG9B	ATL1	ATL2	ATL3	ATP10A	ATP10B	ATP10D	ATP11A	ATP11B	ATP11C	ATP13A2	ATP1B1	ATP2C1	ATP8A1	ATP8A2	ATP8B1	ATP8B2	ATP8B3	ATP8B4	ATP9A	ATP9B	ATR	AURKB	AZIN2	BAG6	BAIAP2	BAIAP2L1	BAIAP2L2	BANF1	BCS1L	BECN1	BET1	BET1L	BIN1	BIN2	BIN3	BLTP1	BLTP3B	BNIP1	BROX	BTBD8	C2CD2L	C9orf72	CALM3	CAMLG	CAV1	CAV2	CAV3	CAVIN2	CCDC47	CCDC88A	CD2	CD24	CD36	CDC42	CDH2	CDK1	CEP55	CERS2	CERT1	CHCHD10	CHCHD3	CHCHD6	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4BP1	CHMP4C	CHMP5	CHMP6	CHMP7	CHP1	CHRDL1	CHRNB1	CIBAR1	CIDEA	CIDEB	CIDEC	CLCN2	CLN3	CLPTM1L	CLTRN	CLU	CNTN2	CNTNAP2	COL5A1	COLEC12	CORO1C	COX18	CPTP	CR1	CSNK1D	CTDNEP1	CTSL	CUL3	CXCR4	DBNL	DCSTAMP	DCTN1	DEGS1	DES	DLG4	DMKN	DMPK	DNAJA3	DNAJC11	DNM1	DNM1L	DNM2	DNM3	DOCK1	DPP4	EEA1	EGFR	EHD2	ELMO1	EMC1	EMC10	EMC2	EMC3	EMC4	EMC6	EMC7	EMC8	EMC9	EMD	EMP2	EPB41L3	EPHB2	ESYT1	EXOC1	EXOC2	EXOC3	EXOC4	EXOC5	EXOC6	EXOC6B	EXOC7	EXOC8	FA2H	FABP1	FASLG	FCGR1A	FCHO2	FCHSD1	FCHSD2	FER1L5	FLOT1	FNBP1L	FNTA	GAS6	GBA2	GBF1	GCA	GET1	GET3	GET4	GHITM	GLTP	GLTPD2	GOLPH3	GOLPH3L	GOSR1	GOSR2	GPER1	GPHN	GRIN3B	GSN	GULP1	HACE1	HAVCR1	HDAC3	HGS	HILPDA	HIP1R	HSD17B13	HSPA8	HSPA9	HUWE1	ICA1	ICA1L	IL1RAPL1	ILK	IMMT	IQGAP1	IRAG2	IST1	ITGAM	ITGB2	KCNB1	KCNIP2	KIF20A	KLHL12	LEMD2	LETM1	LHFPL4	LMNA	LMNB1	LMNB2	LPCAT2	LPCAT3	LPIN1	LRCH4	LRP4	LRRC4	MAFB	MAIP1	MAL	MAPK15	MARCO	MEGF10	MFN2	MFSD2A	MIA3	MICALL1	MICALL2	MICOS10	MICOS13	MITD1	MMGT1	MOAP1	MSR1	MTCH1	MTCH2	MTMR3	MTMR4	MTSS1	MTSS2	MTTP	MTX1	MTX2	MTX3	MUSK	MVB12A	MX1	MX2	MYADM	MYH9	MYO18A	MYOC	MYOF	MYRF	NAPA	NAPG	NAXE	NCLN	NDRG1	NDRG4	NDUFA13	NECTIN2	NEK6	NEMP1	NHERF1	NKD2	NLGN1	NLGN2	NLGN3	NLGN4X	NME3	NME4	NOMO1	NOMO2	NOMO3	NPC1	NRCAM	NRXN1	NRXN2	NSFL1C	NUP155	NUP93	OCRL	OPA1	OSBP	OSBPL10	OSBPL11	OSBPL2	OSBPL5	OSBPL6	OSBPL8	OSBPL9	OTOF	OXA1L	P2RX7	PACSIN1	PACSIN2	PACSIN3	PADI4	PALS1	PDCD6	PDCD6IP	PEF1	PICALM	PICK1	PIK3C2A	PIKFYVE	PIP4K2A	PIP4K2B	PIP5K1C	PITPNA	PITPNB	PITPNC1	PITPNM1	PITPNM2	PITPNM3	PLA2G5	PLAAT3	PLEC	PLEKHA8	PLEKHA8P1	PLEKHM1	PLK1	PLSCR1	PLSCR2	PLSCR3	PLSCR4	PLSCR5	PLTP	PMP2	PPP6C	PPT1	PREB	PRELID1	PRELID2	PRELID3A	PRELID3B	PRKCA	PRKCB	PRKCI	PRRT2	PRX	PTEN	PTPRC	PTPRD	RAB14	RAB1A	RAB20	RAB2A	RAB34	RAB39A	RAB3A	RAB4B	RAB5IF	RAB7A	RAB7B	RAB8A	RABEP1	RABIF	RAC1	RAPSN	RCC1	REEP1	REEP3	REEP4	REEP5	RELN	RFT1	RFTN1	RHOA	RILP	RILPL1	RILPL2	RIMS1	ROMO1	RTN1	RTN2	RTN3	RTN4	RTP1	RTP2	RTP3	RTP4	RTP5	RUBCNL	RUFY1	RUFY4	S100A10	SAMD9	SAMM50	SAR1A	SAR1B	SCAP	SCLT1	SEC13	SEC16A	SEC22A	SEC22B	SEC23A	SEC23B	SEC24A	SEC24B	SEC24C	SEC24D	SEC31A	SEC31B	SEC61A1	SERINC2	SERINC3	SERINC5	SERP1	SGCZ	SGTA	SH3BP1	SH3GL1	SH3GL2	SH3GL3	SH3GLB1	SH3GLB2	SHANK3	SHISA7	SIRT2	SLC25A46	SLC66A2	SMPD1	SMURF1	SNAP23	SNAP25	SNAP29	SNAP47	SNAP91	SNCA	SNF8	SNX1	SNX18	SNX3	SNX33	SNX5	SNX9	SOD1	SOX30	SPART	SPAST	SPG11	SPIRE1	SPIRE2	SPTBN1	SPTBN4	STAM	STAM2	STARD7	STEEP1	STX10	STX11	STX12	STX16	STX17	STX18	STX19	STX1A	STX1B	STX2	STX3	STX4	STX5	STX6	STX7	STX8	STXBP1	STXBP6	SURF4	SYNGR1	SYNGR2	SYNJ1	SYNJ2	SYP	SYT1	SYT11	SYT4	SYT7	SYTL4	TAFAZZIN	TARDBP	TBC1D20	TFG	TGFBRAP1	THBS1	TIMD4	TIMM10	TIMM10B	TIMM13	TIMM22	TIMM29	TIMM50	TIMM8A	TIMM8B	TIMM9	TLCD1	TLCD2	TMCC1	TMCO1	TMED10	TMED2	TMED9	TMEM11	TMEM126A	TMEM147	TMEM170A	TMEM175	TMEM30A	TMEM30B	TMEM33	TMEM41B	TMEM43	TMEM63B	TNFAIP8L3	TOM1	TOMM20	TOMM22	TOMM40	TOMM5	TOMM6	TOMM7	TOMM70	TOR1A	TOR1AIP1	TOR1AIP2	TOR1B	TRAM1	TRAM1L1	TRAM2	TRAPPC1	TRAPPC10	TRAPPC11	TRAPPC12	TRAPPC13	TRAPPC2	TRAPPC2B	TRAPPC2L	TRAPPC3	TRAPPC4	TRAPPC5	TRAPPC6A	TRAPPC6B	TRAPPC8	TRAPPC9	TRDN	TRIAP1	TRIM72	TRMT10B	TRPC5	TSG101	TSNARE1	TTPA	UBAP1	UBE2I	UBL4A	UBXN2A	UBXN2B	UGCG	UQCC3	USE1	USO1	UVRAG	VAMP1	VAMP2	VAMP3	VAMP4	VAMP7	VAMP8	VAPA	VAPB	VAT1	VCPIP1	VDAC2	VIPAS39	VMP1	VPS11	VPS16	VPS18	VPS25	VPS28	VPS33A	VPS33B	VPS36	VPS37A	VPS37B	VPS37C	VPS37D	VPS39	VPS41	VPS4A	VPS4B	VPS8	VRK1	VTI1A	VTI1B	WASL	WDR83OS	WHAMM	WNK1	XKR4	XKR6	XKR7	XKR8	YIPF4	YIPF5	YIPF7	YJEFN3	YKT6	ZFYVE19	ZFYVE26	ZMPSTE24
KE831_Disturbance_Lysosomal_function_GO:0007040	lysosome organization	ABCA1	ACP2	AKTIP	AP5B1	AP5M1	AP5S1	AP5Z1	ARL8B	ARSB	ATP10B	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4C	CHMP5	CHMP6	CHMP7	CLN3	CLN5	CLN6	CLVS1	CLVS2	CORO1A	CREG1	FHIP1B	GAA	GBA1	GNPTAB	GRN	HOOK1	HOOK2	HOOK3	HPS1	HPS4	LAMTOR1	LRRK2	LYSET	LYST	MBTPS1	MFSD8	MYO7A	NAGPA	OSBPL10	OSBPL11	OSBPL9	PI4KB	PIKFYVE	PLA2G5	RAB14	RAB20	RAB34	RAB39A	RAB7A	RAB7B	RUFY4	SNAPIN	SPG11	SRPX	SYT7	TFE3	TFEB	TMEM106B	TMEM175	TMEM63A	TPCN2	TPP1	VIPAS39	VPS18	VPS33B	VPS35	ZFYVE26	ZKSCAN3
KE896_Parkinsonian_motor_deficits_GO:0007626	locomotory behavior	ABAT	ABCA2	ADCY8	ADORA2A	ANKH	APOE	APP	ARRB2	ATP1A2	ATP7A	AVP	BACE1	BTBD9	C1QL1	CASP3	CHRNA3	CHRNB2	CIART	CNTN1	CRBN	CXCL12	DLG4	DMRT3	DRD1	DRD2	DRD3	DRD4	EGR1	EN1	FOXA2	GAL	GDNF	GIT1	GPR52	GRM1	GRM6	HPGDS	HTR2C	ID2	INPP5F	KCND2	LRRK2	MC3R	MTA1	NCOA2	NCOR1	NLGN2	NPY2R	NTF4	OPRK1	PAFAH1B1	PENK	PEX13	PLN	PNOC	PRKN	PTEN	PUM1	QRFP	RASD2	SEZ6	SEZ6L	SEZ6L2	SLC1A1	SOD1	STRN	TH	TMBIM4	TSC1	TUBA1A	USP2	ZNF212
KE958_Displacement_Serum_thyroxine_T4_from_transthyretin_GO:0070327	thyroid hormone transport	CRYM	SERPINA7	SLC16A10	SLC16A2	SLC17A4	SLC3A2	SLC7A5	SLC7A8	SLCO1B1	SLCO1C1	SLCO4A1	TUBB1
KE959_Increased_Free_serum_thyroxine_T4_GO:0070327	thyroid hormone transport	CRYM	SERPINA7	SLC16A10	SLC16A2	SLC17A4	SLC3A2	SLC7A5	SLC7A8	SLCO1B1	SLCO1C1	SLCO4A1	TUBB1
KE1096_Increased_blood_uric_acid_concentration_GO:0046415	urate metabolic process	ABCG2	CARMIL1	GCKR	PNP	PRPS1	SLC16A9	SLC17A1	SLC17A3	SLC22A11	SLC22A12	SLC2A9
KE1096_Increased_blood_uric_acid_concentration_GO:0015747	urate transport	ABCC4	ABCG2	SLC17A1	SLC17A2	SLC17A3	SLC17A4	SLC22A12	SLC22A13	SLC23A1	SLC2A9
KE1098_Increased_blood_potassium_concentration_GO:0055075	potassium ion homeostasis	ATP12A	ATP1A1	ATP1A2	ATP1A3	ATP1A4	ATP1B1	ATP1B2	ATP1B3	ATP4A	ATP4B	CYP11B2	FXYD1	FXYD3	FXYD4	FXYD5	FXYD6	FXYD7	KCNA5	KCNH2	KCNJ2	KCNMA1	KCNQ1	KCTD7	KLHL3	PRKACA	SLC12A1	SLC12A2	SLC12A3	SLC12A4	SLC12A5	SLC12A6	SLC12A7	SLC12A8	SLC12A9	WNK1	YWHAE
KE1290_Glutathione_homeostasis_GO:0006749	glutathione metabolic process	CHAC1	CHAC2	CNDP2	CTNS	DPEP1	ETHE1	G6PD	GCLC	GCLM	GGT1	GGT2P	GGT3P	GGT5	GGT6	GGT7	GGTLC1	GGTLC2	GGTLC3	GLO1	GLRX2	GPX1	GSR	GSS	GSTA1	GSTA2	GSTA3	GSTA4	GSTA5	GSTK1	GSTM1	GSTM2	GSTM3	GSTM4	GSTM5	GSTO1	GSTO2	GSTP1	GSTT1	GSTT2	GSTT2B	GSTT4	GSTTP2	GSTZ1	HAGH	HPGDS	MGST2	MMACHC	NAT8	OPLAH	SLC1A1	SLC1A2	SNCA	SOD1
KE1351_Activated_NMDA_receptor_GO:0098989	NMDA selective glutamate receptor signaling pathway	APP	CAPN1	DLG4	DORIP1	MEF2C	NLGN1
KE1393_Hepatocytotoxicity_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1413_Reduced_presynaptic_neuron_2_activity_GO:0098928	presynaptic signal transduction	SIPA1L2
KE1414_Decreased_GABA_GO:0009449	GABA biosynthetic process	ABAT	ALDH1A1	GAD1	GAD2	SLC38A1
KE1414_Decreased_GABA_GO:0014051	gamma-aminobutyric acid secretion	BEST1	CRH	PNOC
KE1415_Reduced_GABA_A_receptor_activation_GO:0007214	gamma-aminobutyric acid signaling pathway	ATF4	GABBR1	GABBR2	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB1	GABRB2	GABRB3	GABRD	GABRE	GABRG1	GABRG2	GABRG3	GABRQ	GABRR1	GABRR3	GNAI2	GPR156	PLCL1	PLCL2	SHISA7	SLC12A2
KE1416_Decreased_intracellular_chloride_GO:0030644	intracellular chloride ion homeostasis	FASLG	KCNE3	KCNQ1	SLC12A2	SLC12A5	STK39	TBXAS1	WNK1	WNK4
KE1417_NFE2_Nrf2_repression_GO:0034599	cellular response to oxidative stress	ABCC1	ABL1	ABL2	ADPRS	AGAP3	AIF1	AIFM1	ALB	ALDH3B1	ANKZF1	APOA4	AQP1	ARNT	ATF2	ATF4	ATM	ATP13A2	ATP7A	BECN1	BMAL1	BNIP3	BRF2	BTK	CAMKK2	CAT	CBX8	CCS	CD36	CDK1	CFL1	CHCHD2	CIAPIN1	CRYGD	CUL1	CUL3	CYGB	CYP1B1	DAPK1	DHRS2	ECT2	EDN1	EDNRA	EIF2S1	ENDOG	ERCC6L2	ERMP1	ERN1	ETV5	FABP1	FANCC	FBXO31	FER	FOS	FOXO1	FOXO3	FXN	FYN	G6PD	GPR37	GPR37L1	GPX1	GPX2	GPX3	GPX4	GPX5	GPX6	GPX7	GPX8	GSR	HDAC2	HDAC6	HIF1A	HM13	HSPA1A	HSPA1B	HTRA2	IL18BP	IL18RAP	IL6	KAT2B	KEAP1	KLF2	KLF4	LCN2	LONP1	LRRK2	MAP1LC3A	MAP2K4	MAP3K5	MAPK13	MAPK7	MAPK8	MAPK9	MAPT	MB	MDM2	MGAT3	MGST1	MMP3	MSRA	MT3	MYB	NDOR1	NET1	NFE2L2	NOS3	NPPA	NQO1	NUDT2	OGG1	OSER1	PAM	PARK7	PARP1	PCNA	PDCD10	PDGFD	PDGFRA	PDK2	PENK	PEX10	PEX12	PEX13	PEX14	PEX2	PEX5	PINK1	PJVK	PKD2	PLA2R1	PLEKHA1	PNPT1	PPARGC1A	PPEF2	PPIA	PPIF	PPP5C	PRDX1	PRDX2	PRDX3	PRDX5	PRKAA1	PRKAA2	PRKCD	PRKD1	PRKN	PRR5L	PTPRK	PXN	PYCR1	PYCR2	PYROXD1	RAD52	RBM11	RBX1	RELA	RHOB	RIPK1	RIPK3	ROMO1	RPS3	SELENOS	SESN2	SETX	SIN3A	SIRPA	SIRT1	SIRT2	SLC25A24	SLC4A11	SNCA	SOD1	SOD2	SOD3	SRC	SRXN1	STAU1	STAU2	STK24	STK25	STK26	STX2	STX4	SUMO4	TBC1D24	TET1	TMEM161A	TNFAIP3	TOP2B	TP53	TPM1	TRPA1	TRPM2	TXN	UCP1	VKORC1L1	VRK2	WNT16	ZC3H12A	ZNF580
KE1419_Reduced_FXR_activity_GO:0038185	nuclear receptor-mediated bile acid signaling pathway	NR1H4	VDR
KE1421_Activated_LXR_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE1422_Reduced_PPARalpha_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE1423_Reduced_HSD17B4_activity_GO:0006635	fatty acid beta-oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ADIPOQ	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HADH	HADHA	HADHB	HSD17B10	HSD17B4	IVD	MCAT	MTLN	PEX2	PPARD	SCP2	SLC25A17	SLC27A2
KE1424_Reduced_fatty_acid_beta_oxidation_GO:0006635	fatty acid beta-oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ADIPOQ	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HADH	HADHA	HADHB	HSD17B10	HSD17B4	IVD	MCAT	MTLN	PEX2	PPARD	SCP2	SLC25A17	SLC27A2
KE1456_Increase_Differentiation_of_fibroblasts_GO:0048762	mesenchymal cell differentiation	AKNA	AMELX	ARB2A	BMP2	BMP7	CDC42	CDH2	CORO1C	CTNNB1	CUL1	CUL7	CYP26C1	DDX17	DDX5	DLG5	EDN1	EDNRA	EFNA1	ENG	EOMES	EPB41L5	ERBB4	FAM83D	FBXL17	FGF12	FGF8	FGFR1	FGFR2	FN1	FOLR1	FOXC1	FOXF2	FRZB	GDNF	GFAP	GSC	GSK3B	HAND2	HAS2	HEY1	HEY2	HEYL	HGF	HIF1A	HMGA2	HNRNPAB	HTR2B	IGF1	ISL1	JAG1	KBTBD8	KLHL12	LEF1	LOXL2	LOXL3	LRP6	MEF2C	MSX1	NCAM1	NOG	NOLC1	NOTCH1	NOTCH4	NRG1	NRP1	NRP2	NRTN	OLFM1	OSR1	OTUD5	PAX2	PDCD4	PDCD6	PEF1	PHACTR4	PHOX2B	PITX2	POLR1B	RADIL	RANBP3L	RBPJ	RBX1	ROCK1	ROCK2	S100A4	SEMA3A	SEMA3B	SEMA3C	SEMA3D	SEMA3E	SEMA3F	SEMA3G	SEMA4A	SEMA4B	SEMA4C	SEMA4D	SEMA4F	SEMA4G	SEMA5A	SEMA5B	SEMA6A	SEMA6B	SEMA6C	SEMA6D	SEMA7A	SHH	SIX1	SIX2	SKP1	SLC39A10	SLC39A6	SMAD4	SNAI1	SNAI2	SOX10	SOX8	SOX9	SP6	SPRY1	STAT1	TAPT1	TASOR	TBX1	TBX20	TBX3	TCF21	TCOF1	TGFB1	TGFB2	TGFBR1	TGFBR2	TGFBR3	TGFBR3L	TRIM28	WNT4	WNT5A	WNT8A	ZFP64
KE1458_Pulmonary_fibrosis_GO:0030198	extracellular matrix organization	ADAM10	ADAM15	ADAM8	ADAMTS1	ADAMTS10	ADAMTS12	ADAMTS13	ADAMTS14	ADAMTS15	ADAMTS16	ADAMTS17	ADAMTS18	ADAMTS19	ADAMTS2	ADAMTS20	ADAMTS3	ADAMTS4	ADAMTS5	ADAMTS6	ADAMTS7	ADAMTS8	ADAMTS9	ADAMTSL1	ADAMTSL2	ADAMTSL3	ADAMTSL5	APLP1	APP	ATP7A	BMP1	C6orf15	CCDC80	CLASP1	CLASP2	CMA1	COL10A1	COL11A1	COL11A2	COL12A1	COL13A1	COL14A1	COL15A1	COL16A1	COL17A1	COL18A1	COL19A1	COL1A1	COL1A2	COL22A1	COL23A1	COL24A1	COL27A1	COL28A1	COL2A1	COL3A1	COL4A1	COL4A2	COL4A3	COL4A4	COL4A5	COL4A6	COL5A1	COL5A2	COL5A3	COL6A5	COL6A6	COL7A1	COL8A1	COL8A2	COL9A1	COL9A2	COL9A3	COLEC12	COLGALT1	COLGALT2	COLQ	CREB3L1	CRTAP	CTSG	CTSK	CTSS	CTSV	CYP1B1	DAG1	DDR2	DMP1	DPT	ECM2	EFEMP2	ELANE	ELN	EMILIN1	EXOC8	FBLN1	FBLN5	FERMT1	FLOT1	FLRT2	FMOD	FURIN	GAS6	GFOD2	GPM6B	GREM1	HAS1	HAS2	HAS3	HMCN1	HPN	HPSE2	IBSP	ITGA2	ITGB1	KIF9	KLK4	KLK5	KLK7	LAMC1	LOX	LOXL1	LOXL2	LOXL3	LOXL4	LUM	MANSC4	MARCO	MATN1	MATN2	MATN3	MATN4	MFAP4	MIA	MMP1	MMP10	MMP11	MMP12	MMP13	MMP14	MMP15	MMP16	MMP17	MMP19	MMP2	MMP20	MMP21	MMP23B	MMP24	MMP25	MMP26	MMP27	MMP28	MMP3	MMP7	MMP8	MMP9	MPV17	MYH11	MYO1E	NDNF	NF1	NID1	NID2	NOXO1	NPHS1	NPNT	NTN4	OPTC	OTOL1	P3H4	P4HA1	P4HA3	PAPLN	PHLDB1	PHLDB2	PLG	PLOD1	PLOD2	PLOD3	POSTN	PRICKLE1	PRSS1	PRSS2	PXDN	PXDNL	QSOX1	RAMP2	RECK	SCX	SERPINF2	SERPINH1	SH3PXD2B	SLC39A8	SMOC1	SMOC2	SPINK5	SPINT1	SPOCK2	ST7	SULF1	SULF2	TGFB1	TGFB2	TGFBI	TGFBR1	TGM2	TLL1	TLL2	TMPRSS6	TNXB	TPSAB1	VIT	WASHC1	WT1
KE1468_Activation_Latent_Transforming_Growth_Factor_Beta_1_GO:0071604	transforming growth factor beta production	CHI3L1	COL3A1	FOSL2	IL13	IL13RA2	ITGAV	ITGB6	JUN	TMEM219
KE1469_Activation_Transforming_Growth_Factor_beta_pathway_GO:0007179	transforming growth factor beta receptor signaling pathway	ACVR1	ACVRL1	ADAM9	APPL1	APPL2	ARRB2	BAMBI	BMPR1A	CDH5	CDKN2B	CITED1	CLDN5	COL1A2	COL3A1	CREB1	DAB2	DUSP22	EID2	ENG	FERMT2	FMOD	FNTA	FOS	FOXH1	FSHB	FURIN	GCNT2	GDF10	GDF11	GDF15	GDF5	GDF9	HPGD	ID1	ITGB5	JUN	LEFTY1	LRRC32	LTBP2	LTBP3	MAP3K7	MSTN	NLK	NRROS	PARP1	PSG9	PTK2	PTPRK	PXN	RGCC	SIRT1	SKI	SMAD1	SMAD2	SMAD3	SMAD4	SMAD5	SMAD7	SMAD9	SPI1	SRC	STAT3	TGFB1	TGFB2	TGFB3	TGFBR1	TGFBR2	TGFBR3	TGFBR3L	TGFBRAP1	USP15	USP9X	USP9Y	WFIKKN1	WFIKKN2	ZFYVE9	ZMIZ1	ZYX
KE1481_Inhibition_of_mitochondrial_DNA_polymerase_gamma_Pol_gamma_GO:0006264	mitochondrial DNA replication	DNA2	MGME1	POLG	POLG2	POLRMT	PRIMPOL	RRM1	RRM2B	SSBP1	TWNK
KE1482_Depletion_mtDNA_GO:0032042	mitochondrial DNA metabolic process	DNA2	ENDOG	LIG3	MGME1	NEURL4	PARP1	POLG	POLG2	POLRMT	PRIMPOL	RRM1	RRM2B	SSBP1	TOP3A	TWNK
KE1486_Binding_of_substrate_endocytic_receptor_GO:0006898	receptor-mediated endocytosis	ACE2	ACKR3	ADM	ADRB2	AMN	AP1S1	AP2A1	AP2A2	AP2B1	AP2M1	AP2S1	AP3M1	APOE	ARHGAP27	ARHGEF37	ARR3	ARRB1	ARRB2	ASGR1	CALCRL	CALY	CANX	CAV1	CAV2	CAV3	CCDC158	CD14	CD36	CD81	CD9	CEACAM1	CLEC4M	CLEC9A	CLN3	CLTA	CLTB	CLTC	CLTCL1	CTSL	CTTN	CUBN	CXCL16	CXCL8	CXCR1	CXCR2	DAB2	DLL1	DNAJC13	DNAJC6	DNM1	DNM2	DPP4	DRD2	DRD3	ENTREP1	EPS15	FCER1G	FCER2	FCGR2B	FCHO1	FCHO2	FCHSD2	FCMR	FNBP1L	FOLR1	FPR2	GAK	GAS7	GPR107	GRB2	GRIA1	GRK2	GRK3	GRK4	GTF2H2	HFE	HGS	HIP1R	HMMR	HSPA8	HSPG2	IGF2R	INPP5F	INSR	ITCH	ITGA4	ITGAM	ITGB1	ITGB2	ITSN1	ITSN2	LDLR	LDLRAD3	LDLRAP1	LILRB1	LILRB4	LMBR1L	LMBRD1	LRP1	LRP1B	LRP2	LRP3	LY75	LYVE1	M6PR	MAGI2	MARCO	MICALL1	MRC1	MRC2	MSR1	NEDD4	NEDD4L	NLGN3	PDLIM7	PI4KB	PICALM	PIKFYVE	PIP5K1C	PLA2R1	PLXNB2	PPT1	RAB15	RAB31	RAB5A	RAB9A	RAB9B	RABEPK	RALA	RALB	RALBP1	RAMP1	RAMP2	RAMP3	RNASEK	SAG	SCARB2	SCARF1	SCYL2	SDC1	SFTPD	SGIP1	SIGLEC1	SLC9B2	SNAP91	SNCA	SNX1	SNX9	SORL1	STAB1	STAB2	STON1	STON2	SYK	SYNJ1	SYNJ2	TFR2	TFRC	TMEM108	TPCN2	VLDLR	WASF1
KE1488_Glutamate_dyshomeostasis_GO:0090461	intracellular glutamate homeostasis	GLS	KCTD7
KE1491_Increased_Oncotic_Necrosis_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1498_Loss_of_alveolar_capillary_membrane_integrity_GO:0061028	establishment of endothelial barrier	AFDN	CLDN1	CLDN3	EDNRA	EDNRB	EZR	F11R	F2RL1	FOXP3	HPSE	ICAM1	MARVELD2	MSN	MYADM	PDE2A	PDE4D	PECAM1	PPP1R16B	RAP1A	RAP1B	RAP1BL	RAP2C	RAPGEF1	RAPGEF2	RAPGEF3	RDX	ROBO4	SOX18	TJP1	TJP2	TJP3
KE1499_Increased_activation_of_T_T_helper_h_type_2_cells_GO:0035712	T-helper 2 cell activation	TNFSF4
KE1500_Increased_fibroblast_proliferation_and_myofibroblast_differentiation_GO:0048144	fibroblast proliferation	COL3A1	WNT7B	ZNF416
KE1500_Increased_fibroblast_proliferation_and_myofibroblast_differentiation_GO:0036446	myofibroblast differentiation	TGFB1	TGFBR1	ZEB2
KE1501_Increased_extracellular_matrix_deposition_GO:0085029	extracellular matrix assembly	ATP7A	COL3A1	COL8A1	COL8A2	DAG1	EFEMP2	ELN	EMILIN1	FBLN5	GAS6	GPM6B	HAS1	HAS2	HAS3	LOX	MFAP4	MYH11	NTN4	PRICKLE1	PXDN	PXDNL	QSOX1	RAMP2	TGFB1	TNXB
KE1508_CYP2E1_Activation_GO:0006805	xenobiotic metabolic process	AADAC	ABCB1	ABCB11	ABCC1	ABCC2	ABCC3	ABCC4	ABCC5	ABHD10	ACAA1	ACSL1	ACSM1	ACSM2B	ADA	AHR	AHRR	AKR1C1	ALDH2	ALDH3A1	AOC2	AOX1	ARNT	ARNT2	AS3MT	BCHE	BPHL	CAD	CBR1	CBR3	CES2	CES3	CMBL	CRYZ	CYB5B	CYP1A1	CYP1A2	CYP1B1	CYP26A1	CYP26B1	CYP2A13	CYP2A6	CYP2A7	CYP2B6	CYP2C18	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP2D7	CYP2E1	CYP2F1	CYP2J2	CYP2R1	CYP2S1	CYP2U1	CYP2W1	CYP3A4	CYP3A5	CYP3A7	CYP46A1	CYP4F12	CYP4F2	DPYD	EPHX1	FMO2	FMO4	FMO5	GLYAT	GRIN1	GSTA1	GSTA2	GSTA3	GSTA4	GSTA5	GSTM1	GSTM2	GSTM3	GSTM4	GSTO1	GSTO2	GSTP1	GUK1	HEMK2	HNF4A	NAT1	NAT2	NOS1	NQO1	NR1I2	NUDT15	PRKCE	RBBP9	RORA	RORC	S100A12	SLC22A1	SLC22A7	SLC28A2	SLC28A3	SLC29A1	SLC29A3	SLCO1A2	SLCO1B1	SLCO1B3	SLCO2B1	SMOX	SULT1A1	SULT1A2	SULT1A3	SULT1B1	SULT1C3	SULT1C4	SULT2A1	TPMT	UGT1A1	UGT1A10	UGT1A3	UGT1A6	UGT1A7	UGT1A8	UGT1A9	UGT2A1	UGT2A2	UGT2A3	UGT2B11	UGT2B15	UGT2B17	UGT2B4	UGT2B7	UPP2	VKORC1
KE1509_Protein_Adduct_Formation_GO:0008213	protein alkylation	ANTKMT	ATPSCKMT	CAMKMT	CSKMT	EEF1AKMT1	EEF1AKMT2	EEF1AKMT3	EEF2KMT	EHMT1	EHMT2	ETF1	ETFBKMT	FAM98A	FAM98B	GSPT1	HEMK2	ICMT	KMT5A	LCMT1	METTL18	METTL21A	METTL21C	METTL22	NDUFAF7	NTMT1	NTMT2	PCMT1	PRDM12	PRMT1	PRMT3	PRMT5	PRMT7	PRMT8	RAB6A	SETD2	SETD3	SETD6	SETD7	SMYD2	SNRPB	SNRPD3	TRMT112	VCPKMT
KE1511_Lipid_Peroxidation_GO:0034440	lipid oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ACSM1	ADH4	ADH5	ADH7	ADIPOQ	ADIPOR1	ADIPOR2	ALOX12	ALOX12B	ALOX15	ALOX15B	ALOX5	ALOXE3	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	CYGB	CYP4F2	CYP4V2	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HACL1	HACL2	HADH	HADHA	HADHB	HAO1	HAO2	HSD17B10	HSD17B4	IVD	MCAT	MLYCD	MTLN	PEX13	PEX2	PHYH	PLA2G7	POR	PPARD	PPARGC1A	SAMD1	SCP2	SLC25A17	SLC27A2
KE1512_Unfolded_Protein_Response_GO:0030968	endoplasmic reticulum unfolded protein response	AATF	AGR2	AMFR	ASB11	ATF3	ATF4	ATF6	ATF6B	BHLHA15	CDK5RAP3	CREB3	CREB3L1	CREBZF	CTH	DDIT3	DERL1	DERL2	DERL3	DNAJC10	EDEM2	EDEM3	EIF2AK3	EIF2S1	ERLEC1	ERMP1	ERN1	ERN2	HERPUD1	HERPUD2	HSPA1A	HSPA5	MANF	MBTPS1	MBTPS2	NFE2L2	OS9	PARP16	PARP6	PARP8	PTPN1	QRICH1	RHBDD2	RNF7	RPAP2	RTCB	SELENOS	SERP1	SERP2	SIRT1	STAT3	STUB1	TBL2	TMBIM4	TMTC4	VAPB	VCP	WFS1	XBP1	YOD1	ZBTB8OS
KE1514_Neurodegeneration_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1527_Increase_Cell_membrane_depolarization_GO:0051899	membrane depolarization	ABL1	ADORA2A	ANK2	ASIC3	ATP1A2	ATP5IF1	BEST2	CACNA1C	CACNA1D	CACNA1G	CACNA2D1	CACNB2	CAV1	CHRNA1	CHRNA10	CHRNA2	CHRNA3	CHRNA4	CHRNA5	CHRNA6	CHRNA9	CHRNB1	CHRNB2	CHRNB3	CHRNB4	CHRND	CHRNE	CHRNG	CNGB1	EDN1	HCN2	HCN4	KCNH2	KCNJ2	KMT2A	P2RX4	P2RX7	SCN10A	SCN11A	SCN1A	SCN1B	SCN2B	SCN3A	SCN3B	SCN4B	SCN5A	SCN8A	SCN9A	SLC6A4	SLC8A1	TRPC4	TRPM4	YWHAH
KE1538_Decreased_protection_against_oxidative_stress_GO:0034599	cellular response to oxidative stress	ABCC1	ABL1	ABL2	ADPRS	AGAP3	AIF1	AIFM1	ALB	ALDH3B1	ANKZF1	APOA4	AQP1	ARNT	ATF2	ATF4	ATM	ATP13A2	ATP7A	BECN1	BMAL1	BNIP3	BRF2	BTK	CAMKK2	CAT	CBX8	CCS	CD36	CDK1	CFL1	CHCHD2	CIAPIN1	CRYGD	CUL1	CUL3	CYGB	CYP1B1	DAPK1	DHRS2	ECT2	EDN1	EDNRA	EIF2S1	ENDOG	ERCC6L2	ERMP1	ERN1	ETV5	FABP1	FANCC	FBXO31	FER	FOS	FOXO1	FOXO3	FXN	FYN	G6PD	GPR37	GPR37L1	GPX1	GPX2	GPX3	GPX4	GPX5	GPX6	GPX7	GPX8	GSR	HDAC2	HDAC6	HIF1A	HM13	HSPA1A	HSPA1B	HTRA2	IL18BP	IL18RAP	IL6	KAT2B	KEAP1	KLF2	KLF4	LCN2	LONP1	LRRK2	MAP1LC3A	MAP2K4	MAP3K5	MAPK13	MAPK7	MAPK8	MAPK9	MAPT	MB	MDM2	MGAT3	MGST1	MMP3	MSRA	MT3	MYB	NDOR1	NET1	NFE2L2	NOS3	NPPA	NQO1	NUDT2	OGG1	OSER1	PAM	PARK7	PARP1	PCNA	PDCD10	PDGFD	PDGFRA	PDK2	PENK	PEX10	PEX12	PEX13	PEX14	PEX2	PEX5	PINK1	PJVK	PKD2	PLA2R1	PLEKHA1	PNPT1	PPARGC1A	PPEF2	PPIA	PPIF	PPP5C	PRDX1	PRDX2	PRDX3	PRDX5	PRKAA1	PRKAA2	PRKCD	PRKD1	PRKN	PRR5L	PTPRK	PXN	PYCR1	PYCR2	PYROXD1	RAD52	RBM11	RBX1	RELA	RHOB	RIPK1	RIPK3	ROMO1	RPS3	SELENOS	SESN2	SETX	SIN3A	SIRPA	SIRT1	SIRT2	SLC25A24	SLC4A11	SNCA	SOD1	SOD2	SOD3	SRC	SRXN1	STAU1	STAU2	STK24	STK25	STK26	STX2	STX4	SUMO4	TBC1D24	TET1	TMEM161A	TNFAIP3	TOP2B	TP53	TPM1	TRPA1	TRPM2	TXN	UCP1	VKORC1L1	VRK2	WNT16	ZC3H12A	ZNF580
KE1541_Mitochondrial_Complex_I_inhibition_GO:0006120	mitochondrial electron transport, NADH to ubiquinone	COXFA4	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	NDUFA1	NDUFA10	NDUFA11	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFAF1	NDUFB1	NDUFB10	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFC2-KCTD14	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3
KE1542_Inhibition_Mitochondrial_complex_III_GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	CYC1	CYCS	MT-CYB	UQCC3	UQCR10	UQCR11	UQCRB	UQCRC1	UQCRC2	UQCRFS1	UQCRFS1P1	UQCRH	UQCRHL	UQCRQ
KE1543_Mitochondrial_Complex_IV_inhibition_GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	COX4I1	COX4I2	COX5A	COX5B	COX6A1	COX6A2	COX6B1	COX6C	COX7A1	COX7A2	COX7A2L	COX7A2P2	COX7B	COX7B2	COX7C	COX8A	COX8C	COXFA4	CYCS	MT-CO1	MT-CO2	MT-CO3
KE1544_Mitochondrial_Complex_V_inhibition_GO:0042776	proton motive force-driven mitochondrial ATP synthesis	ATP5F1A	ATP5F1B	ATP5F1C	ATP5F1D	ATP5F1E	ATP5F1EP2	ATP5ME	ATP5MF	ATP5MG	ATP5PB	ATP5PD	ATP5PF	ATP5PO	MT-ATP6	MT-ATP8	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	NDUFA1	NDUFA10	NDUFA11	NDUFA12	NDUFA13	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFB1	NDUFB10	NDUFB11	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3	SDHA	SDHB	SDHC	SDHD	STOML2
KE1545_Decreased_mitochondrial_oxidative_phosphorylation_GO:0006119	oxidative phosphorylation	ATP5F1A	ATP5F1B	ATP5F1C	ATP5F1D	ATP5F1E	ATP5F1EP2	ATP5ME	ATP5MF	ATP5MG	ATP5PB	ATP5PD	ATP5PF	ATP5PO	C2orf69	COX4I1	COX4I2	COX5A	COX5B	COX6A1	COX6A2	COX6B1	COX6B2	COX6C	COX7A1	COX7A2	COX7A2L	COX7A2P2	COX7B	COX7B2	COX7C	COX8A	COX8C	COXFA4	CYC1	CYCS	DGUOK	MT-ATP6	MT-ATP8	MT-CO1	MT-CO2	MT-CO3	MT-CYB	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	NDUFA1	NDUFA10	NDUFA11	NDUFA12	NDUFA13	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFAF1	NDUFB1	NDUFB10	NDUFB11	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFC2-KCTD14	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3	SDHA	SDHAF2	SDHB	SDHC	SDHD	SLC25A51	STOML2	UQCC3	UQCR10	UQCR11	UQCRB	UQCRC1	UQCRC2	UQCRFS1	UQCRFS1P1	UQCRH	UQCRHL	UQCRQ
KE1547_Mitochondrial_Injury_GO:0007005	mitochondrion organization	A0ABJ7H8I7	ACAA2	ACAD9	ADCK1	AFG1L	AGK	AGTPBP1	AIFM1	AIFM2	APOO	APOOL	ATAD3A	ATAD3B	ATAD3C	ATF2	ATG3	ATP23	ATP2A1	ATP5F1D	ATP7A	ATPAF1	ATPAF2	BAK1	BAX	BBC3	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L2	BCS1L	BID	BIK	BLOC1S2	BNIP3	BNIP3L	BOK	CALM3	CAMK2A	CAV2	CCAR2	CEP89	CHCHD10	CHCHD2	CHCHD2P9	CHCHD3	CHCHD4	CHCHD6	CHCHD7	CIBAR1	CLPP	CLU	CLUH	CMC1	CNTNAP1	COA1	COA3	COA4	COA5	COA6	COA7	COA8	COX11	COX14	COX16	COX17	COX18	COX19	COX20	COX7A1	COX7A2L	CXADR	DMAC1	DMAC2	DNAJA3	DNAJC11	DNM1L	ECSIT	EDN1	EDNRA	ERBB4	FANCG	FASTKD3	FEZ1	FIS1	FMC1	FOXRED1	FUNDC1	FXN	FZD9	GABPB1	GDAP1	GGCT	GHITM	GSK3B	HIGD1A	HIGD1B	HIGD1C	HIGD2A	HIGD2B	HK2	HSD17B10	HSPA9	HSPD1	HTRA2	IFIT2	IMMT	KIF28P	LETM1	LETM2	LETMD1	LIG3	LONP1	LRRK2	LYRM2	LYRM7	MAIP1	MARCKS	MCL1	MFF	MFN1	MFN2	MICOS10	MICOS13	MIEF1	MIEF2	MIGA1	MIGA2	MOAP1	MSTO1	MT-ND1	MT-ND2	MT-ND4	MT-ND5	MT-ND6	MT-RNR2	MTCH1	MTCH2	MTFP1	MTFR1	MTFR1L	MTFR2	MTM1	MTRNR2L5	MTX1	MTX2	MTX3	MUL1	MYH14	NAIF1	NDUFA13	NDUFA6	NDUFAF1	NDUFAF2	NDUFAF3	NDUFAF4	NDUFAF5	NDUFAF6	NDUFAF7	NDUFAF8	NDUFC2	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS7	NDUFS8	NIPSNAP2	NME3	NOA1	NOL3	NOS3	NPTX1	NUBPL	OCIAD2	OMA1	OPA1	OXA1L	PARK7	PARL	PARP1	PET100	PET117	PHB1	PHB2	PID1	PINK1	PISD	PLD6	PLEC	PLSCR3	PMAIP1	PNPT1	PPARGC1A	PPM1K	PRDX3	PRKACA	PRKN	PTCD2	PTPMT1	PUM2	PYROXD2	RAB29	RAB32	RAB38	RAB5IF	RCC1L	RHOT1	RHOT2	ROMO1	RTL10	SAMM50	SCO1	SCO2	SDHAF1	SDHAF2	SDHAF3	SDHAF4	SFN	SIRT4	SIRT5	SLC25A33	SLC25A46	SMAD3	SMIM20	SOD2	SPATA18	SPATA19	SPG7	STARD7	STMP1	STOML2	STPG1	SUPV3L1	SURF1	TAFAZZIN	TERT	THEM4	THG1L	TIMM10	TIMM10B	TIMM13	TIMM21	TIMM22	TIMM29	TIMM50	TIMM8A	TIMM8B	TIMM9	TIMMDC1	TMEM11	TMEM126A	TMEM126B	TMEM186	TMEM223	TMEM242	TMEM70	TOMM20	TOMM22	TOMM40	TOMM5	TOMM6	TOMM7	TOMM70	TRABD	TRMT10B	TTC19	UCP2	UQCC1	UQCC2	UQCC3	UQCC4	UQCC5	UQCC6	UQCRFS1	USP30	VDAC2	VPS13C	VPS13D	VPS35	VPS54	WASF1	WDR81	YME1L1
KE1548_Necrotic_Tissue_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1574_Inhibition_IKK_complex_GO:0007249	canonical NF-kappaB signal transduction	ADAM8	BCL3	BIRC2	BIRC3	CARD11	CHUK	CREBBP	EP300	HACD3	IKBKB	IKBKG	IRAK1	IRAK2	IRAK4	MAP3K7	MYD88	NFKB1	NFKB2	NFKBIA	NLRC3	NOD2	NPM1	PRDX4	REL	RELA	RELB	RIPK1	RIPK2	TAB1	TAB2	TAB3	TBK1	TLR7	TLR8	TLR9	TRADD	TRAF6	TRIM8
KE1575_Activation_Caspase_8_pathway_GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	BAG3	BAX	BCL2	BID	BIRC2	BIRC3	BLOC1S2	CASP8	CASP8AP2	CFLAR	CRADD	DAB2IP	DAXX	DDX3X	DDX47	DEDD	DEDD2	DELE1	DIABLO	FADD	FAS	FASLG	GABARAP	MOAP1	NGF	RIPK1	SORT1	SPI1	TNF	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF1A	TNFSF10	TRADD	TRAF2	TRAF5	ZDHHC3
KE1576_Activation_Tissue_resident_cells_Kuppfer_cells_GO:0042116	macrophage activation	AGER	AIF1	APP	AZU1	C1QA	C5AR1	CD93	CLU	CRTC3	CX3CL1	CX3CR1	DYSF	EDN2	FCER2	FCGR3A	FOXP1	FPR2	GRN	HAVCR2	HMGB1	IFI35	IFNG	IFNGR1	IFNGR2	IL13	IL1RAP	IL33	IL4	ITGAM	ITGB2	JAK2	LBP	MAPT	NMI	PLCG2	SBNO2	SLC11A1	SNCA	STK39	SYK	TLR1	TLR4	TLR6	TLR9	TMEM106A	TNF	TREM2	TYROBP	WNK4
KE1580_Binding_of_microtubule_stabilizing_agents_MSA_to_microtubules_GO:0000226	microtubule cytoskeleton organization	AAAS	ABRAXAS1	ABRAXAS2	ACTB	AFG2B	AKAP9	ANKFN1	APC2	ARHGEF10	ARL2	ARMC2	ASPM	ATAT1	ATXN3	ATXN7	AUNIP	AURKA	AURKB	AURKC	BBOF1	BBS2	BBS4	BCCIP	BCL2L10	BICD1	BICD2	BIRC5	BRCA2	BRSK1	BRSK2	C2CD3	CALML4	CALML5	CALML6	CAMSAP1	CAMSAP2	CAMSAP3	CAPN6	CCDC102B	CCDC120	CCDC13	CCDC146	CCDC170	CCDC187	CCDC39	CCDC40	CCDC57	CCDC61	CCDC63	CCDC66	CCDC68	CCDC69	CCDC78	CCDC8	CCDC88A	CCDC88B	CCDC88C	CCNB1	CCP110	CCSAP	CCSER2	CDC14A	CDC14B	CDC14C	CDC20B	CDCA8	CDK1	CDK2	CDK5	CDK5R1	CDK5RAP2	CENPA	CENPE	CENPH	CEP120	CEP126	CEP135	CEP152	CEP19	CEP192	CEP20	CEP250	CEP295	CEP350	CEP43	CEP44	CEP63	CEP68	CEP72	CEP85	CETN1	CETN2	CETN3	CFAP100	CFAP157	CFAP206	CFAP43	CFAP44	CFAP46	CFAP47	CFAP58	CFAP65	CFAP69	CFAP73	CFAP74	CFAP91	CFAP97D1	CFL1	CGN	CHD3	CHEK2	CHORDC1	CHP1	CIB1	CKAP5	CLASP1	CLASP2	CLIP1	CLIP2	CLIP3	CLIP4	CLXN	CNTLN	CNTROB	CPAP	CPLANE2	CRIPT	CROCC	CRYAB	CSAG1	CSNK1D	CTNNB1	CUL1	CUL7	CUL9	DAG1	DAW1	DCAF13	DCLK2	DCTN1	DCTN2	DCTN6	DCX	DDB1	DEUP1	DISC1	DLG1	DLGAP5	DNAAF1	DNAAF10	DNAAF11	DNAAF19	DNAAF2	DNAAF3	DNAAF4	DNAAF5	DNAAF6	DNAAF8	DNAH1	DNAH12	DNAH17	DNAH2	DNAH3	DNAH5	DNAH7	DNAH8	DNAI1	DNAI2	DNAI3	DNAI4	DNAJB13	DNAL1	DNM2	DOCK7	DRC1	DRC11	DRC11L	DRC2	DRC4	DRC7	DRC9	DST	DYNC1H1	DYNC1LI1	DYNC1LI2	DYNLT1	DZIP1	E2F4	EFCAB11	EFHC1	EML1	EML2	EML3	EML4	ENKD1	ESPL1	EZR	FAM110A	FBXW11	FBXW5	FER	FGF13	FIGN	FIGNL1	FIGNL2	FLNA	FMN2	FOXJ1	FSD1	FSIP2	GAPDH	GAS2L1	GAS2L2	GAS2L3	GCC2	GJA1	GOLGA2	GPSM1	GPSM2	GTF2B	HAUS1	HAUS2	HAUS3	HAUS4	HAUS5	HAUS6	HAUS7	HAUS8	HDAC3	HDGFL3	HEPACAM2	HOATZ	HOOK1	HOOK2	HOOK3	HTT	HYDIN	IFT56	ILK	INCENP	INO80	INPPL1	INTS13	ITGB1	ITGB1BP2	JHY	KANK1	KASH5	KAT5	KATNA1	KATNAL1	KATNAL2	KATNB1	KATNBL1	KHDC3L	KIAA0753	KIAA1614	KIF11	KIF15	KIF18A	KIF18B	KIF19	KIF20A	KIF21A	KIF23	KIF24	KIF25	KIF2A	KIF2B	KIF2C	KIF3A	KIF3B	KIF4A	KIF4B	KIFBP	KIFC1	KIZ	KNSTRN	KPNB1	LIMK2	LLGL1	LLGL2	LMNA	LRGUK	LRRC23	LSM14A	LZTS2	MAP10	MAP1A	MAP1B	MAP1S	MAP2	MAP4	MAP6	MAP6D1	MAP7	MAP7D1	MAP7D2	MAP7D3	MAP9	MAPRE1	MAPRE2	MAPRE3	MAPT	MARK1	MARK2	MARK3	MARK4	MCIDAS	MID1	MISP	MNS1	MOS	MTCL1	MZT1	MZT2A	MZT2B	NAV1	NAV3	NCKAP5	NCKAP5L	NCOR1	NDC80	NDE1	NDEL1	NEDD1	NEK2	NEK6	NEK7	NIN	NINL	NLRP2	NLRP5	NLRP7	NPM1	NSFL1C	NTMT1	NUDC	NUF2	NUMA1	NUP62	NUSAP1	OBSL1	ODAD1	ODAD2	ODAD3	ODAD4	ODF2	OOEP	PADI6	PAFAH1B1	PARD3	PARD3B	PARD6A	PARD6B	PARD6G	PCLAF	PCM1	PCNT	PDE4DIP	PEX14	PHLDB2	PIBF1	PIERCE1	PIERCE2	PKD2	PKHD1	PLK1	PLK2	PLK3	PLK4	PLK5	POC1B	POC5	POLDIP2	PPFIA1	PPFIBP1	PPP1R12A	PPP2R1A	PPP2R1B	PPP2R3C	PRC1	PRICKLE1	PSRC1	PTEN	PTPA	RAB11A	RACGAP1	RAN	RANBP9	RANGRF	RBM14	RBX1	RCC1	RGS14	RHOA	RMDN1	RNF19A	ROCK2	RP1	RP1L1	RPS3	RSPH1	RSPH4A	RSPH6A	RSPH9	RTTN	SAC3D1	SAPCD2	SASS6	SBDS	SDCCAG8	SETD2	SGO1	SIK3	SKA1	SKA2	SKA3	SKP1	SLAIN1	SLAIN2	SLC16A1	SLK	SMC1A	SMC3	SON	SPACA9	SPAG1	SPAG16	SPAG17	SPAG5	SPAG6	SPAST	SPATA7	SPC25	SPDL1	SPEF1	SPEF2	SPICE1	SPIRE1	SPIRE2	SRGAP2	SRGAP2C	SSNA1	SSX2IP	STAG1	STAG2	STARD9	STIL	STK36	STMN1	STMN2	STMN3	STMN4	STMND1	SUN1	SUN2	SYNE2	TACC1	TACC2	TACC3	TAOK1	TBC1D21	TBCB	TBCD	TBCE	TBCEL	TEDC1	TEDC2	TLE6	TLN1	TNKS	TOGARAM1	TOGARAM2	TPGS1	TPPP	TPPP2	TPPP3	TPX2	TRDN	TRIM36	TRIM46	TRPV4	TTBK2	TTC12	TTK	TTL	TTLL1	TTLL11	TTLL13	TTLL2	TTLL3	TTLL4	TTLL5	TTLL6	TTLL7	TTLL8	TTLL9	TUBA1A	TUBA1B	TUBA1C	TUBA3C	TUBA3D	TUBA3E	TUBA4A	TUBA8	TUBAL3	TUBB	TUBB1	TUBB2A	TUBB2B	TUBB3	TUBB4A	TUBB4B	TUBB6	TUBB8	TUBB8B	TUBD1	TUBE1	TUBG1	TUBG2	TUBGCP2	TUBGCP3	TUBGCP4	TUBGCP5	TUBGCP6	TXNDC9	UBXN2B	UHRF1	ULK4	USP33	UVRAG	UXT	VCP	WASHC5	WDR62	WDR73	WDR90	WRAP73	XRCC2	ZBED3	ZMYND10	ZMYND12	ZNF207	ZPR1	ZW10
KE1581_Disturbance_in_microtubule_dynamic_instability_GO:0046785	microtubule polymerization	ACTB	AKAP9	CCDC57	CCDC66	CEP192	CKAP5	CLASP1	CLASP2	CPAP	CSNK1D	FGF13	GOLGA2	HAUS2	HDGFL3	MAP4	MAP7D3	MAPRE1	MAPT	MZT1	MZT2A	MZT2B	NDE1	NDEL1	NEDD1	NIN	PCNT	RANBP9	SLAIN1	SLAIN2	SSNA1	TPPP	TPPP2	TPPP3	TPX2	TRPV4	TUBA1A	TUBB1	TUBG1	TUBG2	TUBGCP2	TUBGCP3	TUBGCP4	TUBGCP5	TUBGCP6	ZNF207
KE1581_Disturbance_in_microtubule_dynamic_instability_GO:0007019	microtubule depolymerization	CCSAP	CKAP5	KATNB1	KIF18A	KIF18B	KIF19	KIF24	KIF2A	KIF2B	KIF2C	NCKAP5	NCKAP5L	STMN1	STMN2	STMN3	STMN4	STMND1
KE1582_Impaired_axonial_transport_GO:0098930	axonal transport	ACTR10	AP3B1	AP3B2	AP3D1	AP3M1	AP3M2	AP3S1	AP3S2	ARL8A	ARL8B	ARMC10	ARMCX1	ARMCX2	ARMCX3	ARMCX6	ATG16L1	ATG5	BLOC1S1	BLOC1S2	BLOC1S3	BLOC1S4	BLOC1S5	BLOC1S6	DLG2	DST	DTNBP1	DYNC1H1	FBXW11	HAP1	HDAC6	HIF1A	HSBP1	HSPB1	KIF1A	KIF1B	KIF1C	KIF21A	KIF3A	KIF3B	KIF4A	KIF5A	KIF5B	KIF5C	MAP1A	MAPK8IP3	MAPT	MGARP	NEFL	NETO1	OPA1	PAFAH1B1	RAB21	RAB27B	SNAPIN	SOD1	SPAST	SYBU	TERF2	TMEM108	TMEM230	TRIM46
KE1584_Interaction_of_diketones_with_arginine_residues_GO:0018195	peptidyl-arginine modification	KDM8	NDUFAF7	PRMT1	PRMT5	PRMT7	PRMT8
KE1585_Proteasomal_dysfunction_GO:0010498	proteasomal protein catabolic process	ADRM1	AFG2B	AGAP3	AKIRIN2	AMBRA1	AMFR	AMN1	ANAPC1	ANAPC10	ANAPC11	ANAPC13	ANAPC15	ANAPC16	ANAPC2	ANAPC4	ANAPC5	ANAPC7	ANKRD9	ANKZF1	APC	APC2	APPBP2	ARIH2	ARMC5	ARMC8	ARRB1	ARRB2	ASB1	ASB11	ASB2	ASB7	ASB9	ASCC2	ASCC3	ATE1	ATF6	ATXN3	ATXN3L	AUP1	AXIN1	AXIN2	BAG6	BFAR	BIRC2	BMAL1	BRSK2	BTRC	CALR	CALR3	CANX	CCDC47	CCIN	CCNF	CDC16	CDC20	CDC20B	CDC23	CDC26	CDC27	CDC34	CLGN	CLOCK	COP1	CRBN	CSNK1A1	CTNNB1	CUL1	CUL2	CUL3	CUL4A	CUL4B	CUL5	CUL7	DCAF1	DCAF11	DCAF12	DCAF13	DDB1	DDI1	DDI2	DDIT3	DERL1	DERL2	DERL3	DMAC2	DNAJB12	DNAJB9	DNAJC10	DTL	DTX4	ECPAS	ECRG4	EDEM1	EDEM2	EDEM3	ELOB	ELOC	ENC1	ERCC8	ERLEC1	ERLIN1	ERLIN2	FAF1	FAF2	FAM8A1	FBH1	FBXL12	FBXL13	FBXL14	FBXL15	FBXL16	FBXL17	FBXL18	FBXL19	FBXL2	FBXL20	FBXL21P	FBXL22	FBXL3	FBXL4	FBXL5	FBXL6	FBXL7	FBXL8	FBXO10	FBXO11	FBXO15	FBXO16	FBXO17	FBXO2	FBXO21	FBXO22	FBXO24	FBXO25	FBXO27	FBXO28	FBXO3	FBXO30	FBXO31	FBXO32	FBXO33	FBXO34	FBXO36	FBXO38	FBXO39	FBXO4	FBXO40	FBXO41	FBXO42	FBXO43	FBXO44	FBXO45	FBXO46	FBXO47	FBXO48	FBXO5	FBXO6	FBXO7	FBXO8	FBXO9	FBXW10	FBXW11	FBXW12	FBXW2	FBXW4	FBXW5	FBXW7	FBXW8	FBXW9	FEM1A	FEM1B	FEM1C	FOXRED2	FZR1	GAN	GET4	GID4	GID8	GSK3A	GSK3B	HECTD3	HERC2	HERPUD1	HM13	HSP90B1	HSPA5	HUWE1	IFI27	IPP	ITCH	IVNS1ABP	JKAMP	KAT5	KBTBD12	KBTBD13	KBTBD2	KBTBD3	KBTBD4	KBTBD6	KBTBD7	KBTBD8	KCMF1	KCTD10	KCTD13	KCTD17	KCTD2	KCTD5	KDM2A	KDM2B	KEAP1	KIF14	KLHDC1	KLHDC10	KLHDC2	KLHDC3	KLHL1	KLHL10	KLHL11	KLHL12	KLHL13	KLHL14	KLHL15	KLHL17	KLHL18	KLHL2	KLHL20	KLHL21	KLHL22	KLHL23	KLHL24	KLHL25	KLHL26	KLHL28	KLHL29	KLHL3	KLHL30	KLHL31	KLHL32	KLHL34	KLHL35	KLHL36	KLHL38	KLHL4	KLHL40	KLHL41	KLHL42	KLHL5	KLHL6	KLHL7	KLHL8	KLHL9	LMO7	LOC122513141	LRRC58	LRRC75A	LTN1	LZTR1	MAEA	MAN1A1	MAN1A2	MAN1B1	MAN1C1	MARCHF6	MARCHF8	MDM2	MIDN	MKLN1	MTA1	MYCBP2	NCCRP1	NDFIP1	NDFIP2	NEDD4L	NEMF	NFE2L2	NHLRC1	NHLRC3	NPLOC4	NR1D1	NSFL1C	OS9	PCBP2	PCNP	PELI1	PEX10	PEX12	PJA2	PLAA	PMAIP1	PML	PPP2R5C	PRAME	PRAMEF1	PRAMEF10	PRAMEF11	PRAMEF12	PRAMEF13	PRAMEF14	PRAMEF15	PRAMEF17	PRAMEF18	PRAMEF19	PRAMEF2	PRAMEF20	PRAMEF22	PRAMEF25	PRAMEF26	PRAMEF27	PRAMEF33	PRAMEF4	PRAMEF5	PRAMEF6	PRAMEF7	PRAMEF8	PRAMEF9	PRKN	PRPF19	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMA8	PSMB1	PSMB10	PSMB11	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMB8	PSMB9	PSMC1	PSMC2	PSMC3	PSMC4	PSMC5	PSMC6	PSMD1	PSMD11	PSMD12	PSMD13	PSMD14	PSMD2	PSMD3	PSMD4	PSMD6	PSMD7	PSMD8	PSME4	PSMF1	RAB40A	RAB40B	RAB40C	RAD23A	RAD23B	RANBP10	RANBP9	RBCK1	RBX1	RCN3	RFFL	RHBDD1	RHBDD2	RHOBTB3	RIOK3	RMND5A	RMND5B	RNF10	RNF103	RNF121	RNF122	RNF126	RNF139	RNF145	RNF175	RNF185	RNF186	RNF187	RNF216	RNF34	RNF4	RNF41	RNF5	RNF7	SEC61B	SEL1L	SEL1L2	SELENOS	SGTA	SH3BGRL	SHARPIN	SIAH1	SIAH2	SIAH3	SIRT1	SIRT2	SKP1	SKP2	SMURF1	SMURF2	SOCS2	SOCS6	SOCS7	SPOP	SPOPL	SPSB1	SPSB2	SPSB3	SPSB4	STT3B	STUB1	SYVN1	TBL1X	TBL1XR1	TBX21	TCF25	TMEM129	TMEM67	TMUB1	TMUB2	TNFAIP1	TOPORS	TOR1A	TRAF4	TRIM13	TRIM2	TRIM21	TRIM25	TRIM26	TRIM28	TRIM3	TRIM45	TRIM48	TRIM71	TRIM72	TRIM9	TRIP12	TRIP4	TRPC4AP	TSPAN17	UBE2A	UBE2B	UBE2C	UBE2D1	UBE2D3	UBE2G1	UBE2G2	UBE2J1	UBE2J2	UBE2N	UBE2S	UBE2U	UBE2W	UBE3A	UBE3D	UBE4A	UBE4B	UBQLN1	UBQLN2	UBR1	UBR2	UBR3	UBR4	UBR5	UBR7	UBXN1	UBXN10	UBXN11	UBXN2A	UBXN2B	UBXN4	UBXN6	UBXN7	UBXN8	UCHL1	UFD1	USP14	USP19	USP44	VCP	VHL	WDR26	WFS1	WWP1	WWP2	XBP1	YOD1	YPEL5	ZER1	ZFAND2A	ZFAND2B	ZNF574	ZNF598	ZNRF1	ZNRF2	ZNRF4	ZSWIM8	ZYG11B
KE1586_Airway_epithelial_injury_GO:0009611	response to wounding	ACTB	ACTG1	ACVRL1	ADAM17	ADAMTS13	ADIPOR2	ADORA2A	ADORA3	ADRA2A	ADRA2B	ADRA2C	AGER	AK3	ALOX15	ANGPT1	ANGPT2	ANGPT4	ANGPTL1	ANGPTL2	ANGPTL4	ANGPTL6	ANGPTL7	ANO5	ANO6	ANXA5	ANXA8	APOA4	APOD	APOH	ARF4	ARHGAP24	ARHGAP35	ARHGEF19	ARL8B	AURKA	AXL	BLOC1S3	BNIP3	C4BPB	C6orf89	CARMIL2	CCN2	CCR1	CCR2	CD151	CD34	CD36	CD40	CD40LG	CD44	CD59	CD9	CDK1	CDKN1A	CEACAM1	CERS2	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4BP1	CHMP4C	CHMP5	CHMP6	CHMP7	CLDN1	CLIC1	COL3A1	COL5A1	CORO1B	CPB2	CSPG5	CSRP1	CTNNA1	CTSG	CX3CR1	CYP4F11	CYP4F2	DAG1	DCBLD2	DDIT3	DDR1	DGKA	DGKB	DGKD	DGKE	DGKG	DGKH	DGKI	DGKK	DGKQ	DGKZ	DHFR	DPYSL3	DRD2	DSP	DST	EDNRA	ENPP4	ENTPD1	EPB41L4B	EPO	EPPK1	ERBB2	ERBB3	EREG	EVPL	F10	F11	F12	F13A1	F13B	F2	F2R	F2RL1	F2RL2	F2RL3	F3	F5	F7	F8	F9	FBLN1	FER1L5	FERMT3	FGA	FGB	FGF1	FGF10	FGF2	FGF7	FGFR1OP2	FGG	FGL1	FIBP	FLNA	FLRT3	FN1	FOLR1	FZD7	GAP43	GATA1	GATA2	GATA4	GGCX	GIPR	GNA12	GNAQ	GNAS	GP1BA	GP1BB	GP5	GP6	GP9	HBB	HBEGF	HGFAC	HIF1A	HMOX1	HNF4A	HOXB13	HPSE	HRG	HSPB1	IGF1	IL17A	IL6	ILK	INHBB	INS	ISL1	ITGA2	ITGA5	ITGAV	ITGB1	ITGB3	ITGB4	ITGB5	ITPK1	ITPR3	JAK2	JAML	JMJD1C	KCNB1	KCNK2	KDR	KLK6	KLK8	KLKB1	KNG1	KRT6A	LACRT	LCK	LMAN1	LRG1	LYN	LYVE1	MACF1	MAP1B	MAP2K1	MAPK14	MAPK8IP3	MAPK9	MCAM	MDK	METAP1	MIA3	MMP12	MMP2	MMRN1	MORN4	MPIG6B	MRTFA	MTR	MYH9	MYL12A	MYL9	MYOF	MYOZ1	NDNF	NF1	NFKBIZ	NOG	NOTCH2	NPPC	NPR2	NREP	NRG1	NRP1	NTRK1	NTRK3	ODAM	P2RX4	P2RY1	P2RY12	PABPC4	PAFAH2	PAK1	PAX6	PDCD10	PDGFA	PDGFB	PDGFRA	PDPN	PEAR1	PF4	PIK3CA	PIK3CB	PIK3CG	PLAT	PLAU	PLAUR	PLCG2	PLEC	PLEK	PLET1	PLG	PLSCR1	POFUT3	POU5F1	PPIA	PPL	PPP3CA	PRCP	PROC	PROCR	PROS1	PROZ	PRRG1	PRRG2	PRRG3	PRRG4	PRSS56	PTPRJ	RAB3A	RAC1	RAF1	RAP2B	RASA3	REG3A	RHOA	RHOC	RIPOR1	RTN4RL1	RTN4RL2	SAA1	SARM1	SCARB1	SCUBE1	SERPINA1	SERPINA10	SERPINC1	SERPIND1	SERPING1	SFTA3	SLC11A1	SLC6A4	SMAD3	SMPD1	SOD1	SOX2	SPRR3	SRC	SRF	STXBP1	STXBP3	SYK	SYT11	SYT7	SYTL4	TFPI	TFPI2	TGFB1	TGFB2	TGFBR1	THBD	THBS1	TLN1	TLR3	TLR4	TMEFF2	TMIGD3	TNC	TNF	TOR1A	TPM1	TREM2	TREML1	TRIM72	TSKU	TSPO	TUBB1	TYRO3	TYROBP	UBASH3B	UCK2	VASH1	VAV1	VAV2	VAV3	VCL	VEGFA	VKORC1	VPS4A	VPS4B	VWF	WAS	WNT1	WNT5A	WNT7A	YAP1	ZFP36	ZFP36L1	ZFP36L2
KE1587_Fibroproliferative_airway_lesions_GO:0030198	extracellular matrix organization	ADAM10	ADAM15	ADAM8	ADAMTS1	ADAMTS10	ADAMTS12	ADAMTS13	ADAMTS14	ADAMTS15	ADAMTS16	ADAMTS17	ADAMTS18	ADAMTS19	ADAMTS2	ADAMTS20	ADAMTS3	ADAMTS4	ADAMTS5	ADAMTS6	ADAMTS7	ADAMTS8	ADAMTS9	ADAMTSL1	ADAMTSL2	ADAMTSL3	ADAMTSL5	APLP1	APP	ATP7A	BMP1	C6orf15	CCDC80	CLASP1	CLASP2	CMA1	COL10A1	COL11A1	COL11A2	COL12A1	COL13A1	COL14A1	COL15A1	COL16A1	COL17A1	COL18A1	COL19A1	COL1A1	COL1A2	COL22A1	COL23A1	COL24A1	COL27A1	COL28A1	COL2A1	COL3A1	COL4A1	COL4A2	COL4A3	COL4A4	COL4A5	COL4A6	COL5A1	COL5A2	COL5A3	COL6A5	COL6A6	COL7A1	COL8A1	COL8A2	COL9A1	COL9A2	COL9A3	COLEC12	COLGALT1	COLGALT2	COLQ	CREB3L1	CRTAP	CTSG	CTSK	CTSS	CTSV	CYP1B1	DAG1	DDR2	DMP1	DPT	ECM2	EFEMP2	ELANE	ELN	EMILIN1	EXOC8	FBLN1	FBLN5	FERMT1	FLOT1	FLRT2	FMOD	FURIN	GAS6	GFOD2	GPM6B	GREM1	HAS1	HAS2	HAS3	HMCN1	HPN	HPSE2	IBSP	ITGA2	ITGB1	KIF9	KLK4	KLK5	KLK7	LAMC1	LOX	LOXL1	LOXL2	LOXL3	LOXL4	LUM	MANSC4	MARCO	MATN1	MATN2	MATN3	MATN4	MFAP4	MIA	MMP1	MMP10	MMP11	MMP12	MMP13	MMP14	MMP15	MMP16	MMP17	MMP19	MMP2	MMP20	MMP21	MMP23B	MMP24	MMP25	MMP26	MMP27	MMP28	MMP3	MMP7	MMP8	MMP9	MPV17	MYH11	MYO1E	NDNF	NF1	NID1	NID2	NOXO1	NPHS1	NPNT	NTN4	OPTC	OTOL1	P3H4	P4HA1	P4HA3	PAPLN	PHLDB1	PHLDB2	PLG	PLOD1	PLOD2	PLOD3	POSTN	PRICKLE1	PRSS1	PRSS2	PXDN	PXDNL	QSOX1	RAMP2	RECK	SCX	SERPINF2	SERPINH1	SH3PXD2B	SLC39A8	SMOC1	SMOC2	SPINK5	SPINT1	SPOCK2	ST7	SULF1	SULF2	TGFB1	TGFB2	TGFBI	TGFBR1	TGM2	TLL1	TLL2	TMPRSS6	TNXB	TPSAB1	VIT	WASHC1	WT1
KE1604_Inhibition_of_N_linked_glycosylation_GO:0006487	protein N-linked glycosylation	ALG1	ALG10	ALG10B	ALG11	ALG12	ALG13	ALG14	ALG2	ALG3	ALG5	ALG6	ALG8	ALG9	B4GALT1	B4GALT7	DAD1	DDOST	DERL3	DHDDS	DOLPP1	DPAGT1	DPM1	ENGASE	ENTPD5	FUT3	FUT5	FUT6	FUT8	FUT9	GAL3ST1	GANAB	GANC	GFPT1	GFPT2	GNPTAB	GNPTG	HEXA	HEXB	KRTCAP2	MAGT1	MAN1A1	MAN1A2	MAN1B1	MAN1C1	MAN2A1	MAN2A2	MGAT1	MGAT2	MGAT3	MGAT4A	MGAT4B	MGAT4C	MGAT4D	MGAT5	MGAT5B	MOGS	MPDU1	NUS1	OST4	OSTC	PGM3	PMM1	PMM2	POFUT3	PRKCSH	RFT1	RPN1	RPN2	SLC39A8	SRD5A3	ST3GAL1	ST3GAL4	ST6GAL1	ST8SIA1	ST8SIA2	ST8SIA3	ST8SIA4	ST8SIA5	ST8SIA6	STT3A	STT3B	TMEM165	TMEM258	TUSC3	UBE2J1
KE1605_Accumulation_of_misfolded_proteins_GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	AFG1L	AFG3L2	AKIRIN2	ANKZF1	ATXN3	ATXN3L	CLPP	CUL3	FBXL17	HDAC6	IRGQ	KLHL15	LONP1	LONP2	LONRF2	OMA1	OXA1L	PEX10	PEX12	RNF126	SAYSD1	STUB1	TMEM126A	UBE2W	UBR4	UBR5	VCP	YME1L1	ZER1	ZSWIM8	ZYG11B
KE1605_Accumulation_of_misfolded_proteins_GO:0006457	protein folding	AGR2	AHSA1	AHSA2P	AHSP	ALG12	ANP32E	APCS	APLF	ARL2	ATF6	ATPAF2	BAG1	BAG2	BAG3	BAG4	BAG5	CALR	CALR3	CANX	CCDC47	CCT2	CCT3	CCT4	CCT5	CCT6A	CCT6B	CCT7	CCT8	CCT8L1P	CCT8L2	CD74	CDC123	CDC37	CDC37L1	CHORDC1	CLGN	CLPX	CLU	CMC1	COA3	COX14	COX19	CRTAP	CRYAA	CRYAB	CSNK2A1	CWC27	DNAJA1	DNAJA2	DNAJA3	DNAJA4	DNAJB1	DNAJB11	DNAJB12	DNAJB13	DNAJB14	DNAJB2	DNAJB4	DNAJB5	DNAJB6	DNAJB7	DNAJB8	DNAJC10	DNAJC18	DNAJC19	DNAJC2	DNAJC21	DNAJC24	DNAJC25	DNAJC3	DNAJC4	DNAJC5	DNAJC7	DNLZ	ENGASE	ENTPD5	ERO1A	ERO1B	ERP27	ERP29	ERP44	FKBP10	FKBP1A	FKBP1B	FKBP1C	FKBP4	FKBP5	FKBP6	FKBP8	FKBP9	GAK	GRPEL1	GRPEL2	HSP90AA1	HSP90AA2P	HSP90AA4P	HSP90AA5P	HSP90AB1	HSP90AB2P	HSP90AB3P	HSP90AB4P	HSP90B1	HSP90B2P	HSPA13	HSPA14	HSPA1A	HSPA1B	HSPA1L	HSPA2	HSPA4	HSPA4L	HSPA5	HSPA6	HSPA7	HSPA8	HSPA9	HSPB1	HSPB2	HSPB6	HSPBP1	HSPD1	HSPE1	HSPH1	HYPK	KHSRP	LMAN1	LMAN2L	LTBP4	LYRM7	MESD	MKKS	MOGS	MPDU1	NFYC	NGLY1	NKTR	NPPA	NPPB	NPPC	NUDC	NUDCD2	NUDCD3	P3H1	P4HB	PBDC1	PDCL2	PDCL3	PDIA2	PDIA3	PDIA4	PDIA5	PDIA6	PDILT	PDRG1	PEX19	PFDN1	PFDN2	PFDN4	PFDN5	PFDN6	POFUT3	PPIA	PPIAL4A	PPIAL4C	PPIAL4D	PPIAL4E	PPIAL4F	PPIAL4G	PPIAL4H	PPIB	PPIC	PPID	PPIE	PPIF	PPIG	PPIH	PPIL1	PPIL2	PPIL3	PTGES3	PTGES3L	QSOX1	QSOX2	RANBP2	RIC3	RIC8A	RIC8B	RP2	RUVBL2	SACS	SDF2	SDF2L1	SDHAF4	SDIM1	SELENOF	SIL1	ST13	TAPBP	TBCA	TBCC	TBCD	TBCE	TCP1	TELO2	TOR1A	TRAP1	TSC1	TTC1	TTC4	TUBA1A	TXNDC5	UGGT1	UNC45A	UNC45B	VBP1	WDR83OS	WIPF1	ZMYND10	ZPR1
KE1606_Activation_of_hepatic_stellate_cells_GO:0035733	hepatic stellate cell activation	AKAP12	GCLM
KE1607_Increase_Necrosis_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1633_Increase_in_inflammation_GO:0006954	inflammatory response	ABCF1	ABHD8	ACER3	ACKR1	ACKR2	ACOD1	ACVR1	ADAM17	ADAM8	ADCY1	ADCY8	ADGRE2	ADGRE5	ADM	ADORA1	ADORA2A	ADORA3	AFAP1L2	AGER	AGR2	AGTR1	AGTR2	AHSG	AIF1	AIM2	AIMP1	ALOX15	ALOX5	ANO6	ANXA1	AOC3	APCS	APIP	APOL2	APOL3	APP	ASS1	ATRN	AZU1	BCL6	BDKRB1	BDKRB2	BIRC2	BIRC3	BLNK	BMP2	BMP6	BMPR1B	BTK	C15orf39	C1QA	C2CD4A	C2CD4B	C3	C3AR1	C4A	C4B	C5	C5AR1	C5AR2	CAMK1D	CAMK4	CAMP	CARD18	CARD8	CASP1	CASP3	CASP4	CASP6	CASP8	CCL1	CCL11	CCL13	CCL14	CCL15	CCL16	CCL17	CCL18	CCL19	CCL2	CCL20	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL3L1	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCRL2	CD14	CD163	CD180	CD36	CD40	CD40LG	CD44	CD47	CD5L	CD6	CD68	CDO1	CEBPB	CELA1	CERS6	CFH	CHI3L1	CHIA	CHST1	CHST2	CHST4	CHUK	CLEC7A	CLU	CMKLR1	CNR2	CNTF	CRH	CRHBP	CRP	CSF1	CSF1R	CTNNBIP1	CUL3	CX3CL1	CX3CR1	CXCL1	CXCL10	CXCL11	CXCL13	CXCL2	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR2	CXCR3	CXCR4	CXCR6	CYBA	CYBB	DAB2IP	DHX9	DPEP1	DPP9	ELANE	ELF3	EPO	F11R	F12	F2	F2R	F2RL1	F3	F8	FADS2	FCER1A	FCER1G	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FFAR2	FFAR3	FFAR4	FN1	FOLR2	FOS	FPR1	FPR2	FPR3	FUT4	FUT7	GATA3	GBP5	GGT5	GPER1	GPR32	GPR32P1	GPR33	GPR68	GRN	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GZMA	GZMB	GZMK	HAVCR2	HBA1	HBB	HCK	HDAC4	HDAC5	HDAC9	HIF1A	HK1	HLA-DRB1	HMGB1	HMGB2	HMOX1	HNRNPA0	HP	HRH1	HRH4	HSPG2	HYAL1	HYAL3	IFI16	IFI27	IFNA2	IFNG	IFNGR1	IFNGR2	IGHE	IGHG1	IKBKB	IKBKG	IL10RB	IL13	IL17A	IL17B	IL17C	IL17D	IL17F	IL17RA	IL17RC	IL17RE	IL18	IL18R1	IL18RAP	IL1A	IL1B	IL1F10	IL1R1	IL1RAP	IL1RL1	IL1RL2	IL1RN	IL20RA	IL22	IL22RA1	IL23A	IL23R	IL25	IL26	IL27	IL2RA	IL33	IL34	IL36A	IL36B	IL36G	IL36RN	IL37	IL4	IL4R	IL5	IL6	IL6R	IL9	INS	IRAK1	IRAK2	IRAK4	IRF5	IRGM	ITCH	ITGAL	ITGAM	ITGB1	ITGB2	ITIH4	JAK2	KDM4D	KDM6B	KIT	KLKB1	KLRG1	KNG1	KRT16	LACC1	LAT	LBP	LCN2	LGALS9	LIAS	LOXL3	LRP1	LTB4R	LXN	LY75	LY86	LY96	LYN	LYZ	MACIR	MAP3K20	MAP3K7	MAPK9	MAPKAPK2	MAPT	MBL2	MDK	MEFV	MEP1B	MFHAS1	MGLL	MIF	MMP25	MRGPRX1	MSMP	MTOR	MYD88	NAIP	NAMPT	NCR3	NDST1	NFAM1	NFATC3	NFATC4	NFKB1	NFKBID	NFKBIZ	NFX1	NINJ1	NKG7	NLRC4	NLRP1	NLRP10	NLRP2	NLRP3	NLRP4	NLRP6	NLRP9	NOD1	NOS2	NOX1	NOX4	NPFF	NR1H4	NR3C1	NR4A1	NRROS	ODAM	OLR1	ORM1	ORM2	PARK7	PARP4	PF4	PF4V1	PIK3CD	PIK3CG	PJA2	PLA2G2A	PLA2G2D	PLA2G2E	PLA2G4B	PLA2G4C	PLD3	PLD4	PLGRKT	PLSCR1	PNMA1	PPBP	PRDX5	PRKCQ	PRKCZ	PRKD1	PRMT2	PROK2	PSEN1	PSTPIP1	PTAFR	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR	PTN	PTX3	PXK	PYCARD	PYDC2	PYDC5	RAC1	RARRES2	REG3A	REG3G	REL	RELA	RELB	RIPK1	RIPK2	RPS6KA4	RPS6KA5	S100A12	S100A8	S100A9	S1PR3	SAA1	SAA2	SAA4	SBNO1	SCG2	SCN11A	SCUBE1	SELE	SEMA7A	SERPINA1	SERPINA3	SERPINF2	SETD4	SIGIRR	SIGLEC1	SLAMF8	SLC11A1	SLC18A2	SMAD1	SMPDL3B	SNAP23	SNCA	SPINK7	STAB1	STAT3	STK39	SYK	TAB2	TAC1	TAC4	TACR1	TBK1	TBX21	TBXA2R	TFRC	TGFB1	THBS1	THEMIS2	TICAM1	TICAM2	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TMIGD3	TNF	TNFAIP3	TNFAIP6	TNFRSF1A	TNFRSF1B	TNFRSF4	TNFSF4	TNIP1	TNIP2	TNIP3	TOLLIP	TRADD	TRAF2	TRAF3IP2	TRAF5	TREM2	TRIL	TRIM14	TRIM21	TRIM31	TSPAN18	TUSC2	TXNIP	TYROBP	USP14	VCAM1	VNN1	VPS54	WNK4	WNT5A	XCL1	XCL2	XCR1	ZBP1	ZC3H12A	ZEB2	ZNF580
KE1653_Binding_of_inhibitor_to_mitochondrial_complex_III_GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	CYC1	CYCS	MT-CYB	UQCC3	UQCR10	UQCR11	UQCRB	UQCRC1	UQCRC2	UQCRFS1	UQCRFS1P1	UQCRH	UQCRHL	UQCRQ
KE1654_Binding_of_inhibitor_to_mitochondrial_complex_IV_GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	COX4I1	COX4I2	COX5A	COX5B	COX6A1	COX6A2	COX6B1	COX6C	COX7A1	COX7A2	COX7A2L	COX7A2P2	COX7B	COX7B2	COX7C	COX8A	COX8C	COXFA4	CYCS	MT-CO1	MT-CO2	MT-CO3
KE1655_Binding_of_inhibitor_to_mitochondrial_complex_V_GO:0042776	proton motive force-driven mitochondrial ATP synthesis	ATP5F1A	ATP5F1B	ATP5F1C	ATP5F1D	ATP5F1E	ATP5F1EP2	ATP5ME	ATP5MF	ATP5MG	ATP5PB	ATP5PD	ATP5PF	ATP5PO	MT-ATP6	MT-ATP8	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	NDUFA1	NDUFA10	NDUFA11	NDUFA12	NDUFA13	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFB1	NDUFB10	NDUFB11	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3	SDHA	SDHB	SDHC	SDHD	STOML2
KE1656_Antagonism_Thyroid_Receptor_GO:0002154	thyroid hormone receptor signaling pathway	MED1	THRA	THRB
KE1672_Inhibition_of_lung_surfactant_function_GO:0043129	surfactant homeostasis	ABCA3	ADGRF5	BPIFA1	BPIFA4P	CTSH	MBL2	NAPSA	OAS1	RCN3	SFTPD	TMEM63A	TMEM63B	VEGFA
KE1677_Reduced_tidal_volume_GO:0003016	respiratory system process	ECEL1	GAA	NEK10	ODAD4	TNNC1	YWHAZ
KE1708_Th17_cell_migration_and_inflammation_induction_GO:0072538	T-helper 17 type immune response	BATF	ENTPD7	IL17A	IL17B	IL17C	IL17F	IL17RA	IL17RB	IL17RC	IL17RE	IL25	IL6	IL6R	IL6ST	IRF4	JAK1	LY9	NFKBIZ	NOTCH1	PHB1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB10	PSMB2	PSMB3	PSMB4	PSMB8	PSMB9	RORA	RORC	SLAMF6	SOCS3	STAT3	TRAF3IP2
KE1740_Induced_dysregulation_of_ACE2_GO:0002003	angiotensin maturation	ACE	ACE2	ANPEP	ATP6AP2	CMA1	CPA3	CTSG	CTSZ	ENPEP	MME	PRCP	PREP	REN
KE1743_Increase_plasma_Ang_II_GO:0002003	angiotensin maturation	ACE	ACE2	ANPEP	ATP6AP2	CMA1	CPA3	CTSG	CTSZ	ENPEP	MME	PRCP	PREP	REN
KE1750_Increased_inflammatory_immune_responses_GO:0006954	inflammatory response	ABCF1	ABHD8	ACER3	ACKR1	ACKR2	ACOD1	ACVR1	ADAM17	ADAM8	ADCY1	ADCY8	ADGRE2	ADGRE5	ADM	ADORA1	ADORA2A	ADORA3	AFAP1L2	AGER	AGR2	AGTR1	AGTR2	AHSG	AIF1	AIM2	AIMP1	ALOX15	ALOX5	ANO6	ANXA1	AOC3	APCS	APIP	APOL2	APOL3	APP	ASS1	ATRN	AZU1	BCL6	BDKRB1	BDKRB2	BIRC2	BIRC3	BLNK	BMP2	BMP6	BMPR1B	BTK	C15orf39	C1QA	C2CD4A	C2CD4B	C3	C3AR1	C4A	C4B	C5	C5AR1	C5AR2	CAMK1D	CAMK4	CAMP	CARD18	CARD8	CASP1	CASP3	CASP4	CASP6	CASP8	CCL1	CCL11	CCL13	CCL14	CCL15	CCL16	CCL17	CCL18	CCL19	CCL2	CCL20	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL3L1	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCRL2	CD14	CD163	CD180	CD36	CD40	CD40LG	CD44	CD47	CD5L	CD6	CD68	CDO1	CEBPB	CELA1	CERS6	CFH	CHI3L1	CHIA	CHST1	CHST2	CHST4	CHUK	CLEC7A	CLU	CMKLR1	CNR2	CNTF	CRH	CRHBP	CRP	CSF1	CSF1R	CTNNBIP1	CUL3	CX3CL1	CX3CR1	CXCL1	CXCL10	CXCL11	CXCL13	CXCL2	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR2	CXCR3	CXCR4	CXCR6	CYBA	CYBB	DAB2IP	DHX9	DPEP1	DPP9	ELANE	ELF3	EPO	F11R	F12	F2	F2R	F2RL1	F3	F8	FADS2	FCER1A	FCER1G	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FFAR2	FFAR3	FFAR4	FN1	FOLR2	FOS	FPR1	FPR2	FPR3	FUT4	FUT7	GATA3	GBP5	GGT5	GPER1	GPR32	GPR32P1	GPR33	GPR68	GRN	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GZMA	GZMB	GZMK	HAVCR2	HBA1	HBB	HCK	HDAC4	HDAC5	HDAC9	HIF1A	HK1	HLA-DRB1	HMGB1	HMGB2	HMOX1	HNRNPA0	HP	HRH1	HRH4	HSPG2	HYAL1	HYAL3	IFI16	IFI27	IFNA2	IFNG	IFNGR1	IFNGR2	IGHE	IGHG1	IKBKB	IKBKG	IL10RB	IL13	IL17A	IL17B	IL17C	IL17D	IL17F	IL17RA	IL17RC	IL17RE	IL18	IL18R1	IL18RAP	IL1A	IL1B	IL1F10	IL1R1	IL1RAP	IL1RL1	IL1RL2	IL1RN	IL20RA	IL22	IL22RA1	IL23A	IL23R	IL25	IL26	IL27	IL2RA	IL33	IL34	IL36A	IL36B	IL36G	IL36RN	IL37	IL4	IL4R	IL5	IL6	IL6R	IL9	INS	IRAK1	IRAK2	IRAK4	IRF5	IRGM	ITCH	ITGAL	ITGAM	ITGB1	ITGB2	ITIH4	JAK2	KDM4D	KDM6B	KIT	KLKB1	KLRG1	KNG1	KRT16	LACC1	LAT	LBP	LCN2	LGALS9	LIAS	LOXL3	LRP1	LTB4R	LXN	LY75	LY86	LY96	LYN	LYZ	MACIR	MAP3K20	MAP3K7	MAPK9	MAPKAPK2	MAPT	MBL2	MDK	MEFV	MEP1B	MFHAS1	MGLL	MIF	MMP25	MRGPRX1	MSMP	MTOR	MYD88	NAIP	NAMPT	NCR3	NDST1	NFAM1	NFATC3	NFATC4	NFKB1	NFKBID	NFKBIZ	NFX1	NINJ1	NKG7	NLRC4	NLRP1	NLRP10	NLRP2	NLRP3	NLRP4	NLRP6	NLRP9	NOD1	NOS2	NOX1	NOX4	NPFF	NR1H4	NR3C1	NR4A1	NRROS	ODAM	OLR1	ORM1	ORM2	PARK7	PARP4	PF4	PF4V1	PIK3CD	PIK3CG	PJA2	PLA2G2A	PLA2G2D	PLA2G2E	PLA2G4B	PLA2G4C	PLD3	PLD4	PLGRKT	PLSCR1	PNMA1	PPBP	PRDX5	PRKCQ	PRKCZ	PRKD1	PRMT2	PROK2	PSEN1	PSTPIP1	PTAFR	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR	PTN	PTX3	PXK	PYCARD	PYDC2	PYDC5	RAC1	RARRES2	REG3A	REG3G	REL	RELA	RELB	RIPK1	RIPK2	RPS6KA4	RPS6KA5	S100A12	S100A8	S100A9	S1PR3	SAA1	SAA2	SAA4	SBNO1	SCG2	SCN11A	SCUBE1	SELE	SEMA7A	SERPINA1	SERPINA3	SERPINF2	SETD4	SIGIRR	SIGLEC1	SLAMF8	SLC11A1	SLC18A2	SMAD1	SMPDL3B	SNAP23	SNCA	SPINK7	STAB1	STAT3	STK39	SYK	TAB2	TAC1	TAC4	TACR1	TBK1	TBX21	TBXA2R	TFRC	TGFB1	THBS1	THEMIS2	TICAM1	TICAM2	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TMIGD3	TNF	TNFAIP3	TNFAIP6	TNFRSF1A	TNFRSF1B	TNFRSF4	TNFSF4	TNIP1	TNIP2	TNIP3	TOLLIP	TRADD	TRAF2	TRAF3IP2	TRAF5	TREM2	TRIL	TRIM14	TRIM21	TRIM31	TSPAN18	TUSC2	TXNIP	TYROBP	USP14	VCAM1	VNN1	VPS54	WNK4	WNT5A	XCL1	XCL2	XCR1	ZBP1	ZC3H12A	ZEB2	ZNF580
KE1752_Increased_Angiotensin_II_GO:0002003	angiotensin maturation	ACE	ACE2	ANPEP	ATP6AP2	CMA1	CPA3	CTSG	CTSZ	ENPEP	MME	PRCP	PREP	REN
KE1770_Decrease_Mitochondrial_membrane_potential_GO:0051882	mitochondrial depolarization	ABL1	ATP5IF1
KE1792_Toll_like_receptor_4_activation_GO:0034142	toll-like receptor 4 signaling pathway	CD14	CHUK	ECSIT	IRAK1	IRAK2	IRAK4	IRF3	LY96	LYN	MAP3K7	MYD88	NFKBIA	NMI	OAS1	PIK3AP1	PRKCE	RAB11FIP2	RELA	S100A14	SCIMP	TBK1	TICAM1	TICAM2	TIRAP	TLR4	TNIP3	TRAF3	TRAF6	TRIL
KE1794_Pin_1_activation_GO:0000413	protein peptidyl-prolyl isomerization	PIN1	PPIA	PPIL1
KE1795_Latent_Transforming_growth_Factor_beta_expression_GO:0071604	transforming growth factor beta production	CHI3L1	COL3A1	FOSL2	IL13	IL13RA2	ITGAV	ITGB6	JUN	TMEM219
KE1812_Increase_Cytochrome_c_release_GO:0001836	release of cytochrome c from mitochondria	BAK1	BAX	BBC3	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L2	BID	BOK	CLU	FZD9	GGCT	MCL1	PMAIP1	SFN	SMAD3	SOD2	TIMM50
KE1814_benzoquinone_imine_and_acylglucuronide_metabolites_GO:0042178	xenobiotic catabolic process	ACAA1	ACSL1	CRYZ	CYP1A1	CYP1A2	CYP1B1	CYP2A6	CYP2B6	CYP2C18	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP2D7	CYP3A4	CYP3A5	DPYD	GSTM1	GSTM2	GSTM3	GSTM4	GSTO1	NOS1	NR1I2	NUDT15	PRKCE	TPMT	UGT1A10	UGT1A7	UPP2
KE1815_Activation_of_ER_stress_GO:0034976	response to endoplasmic reticulum stress	AATF	ABL1	AFG2B	AGR2	AIFM1	ALOX15	AMFR	ANKS4B	ANKZF1	APAF1	ASB11	ATF3	ATF4	ATF6	ATF6B	ATG10	ATP2A1	ATP2A2	ATP2A3	AUP1	BAG6	BAK1	BAX	BBC3	BCAP31	BCL2	BCL2L11	BHLHA15	BRSK2	CALR	CALR3	CANX	CASP4	CCDC47	CDK5RAP3	CEBPB	CFTR	CHAC1	CLGN	CREB3	CREB3L1	CREB3L2	CREB3L3	CREBZF	CTH	CXCL8	DAB2IP	DDIT3	DDRGK1	DDX3X	DERL1	DERL2	DERL3	DNAJB12	DNAJB9	DNAJC10	DNAJC3	ECPAS	EDEM1	EDEM2	EDEM3	EEF2	EIF2AK3	EIF2B5	EIF2S1	EIF4G1	ERLEC1	ERLIN1	ERLIN2	ERMP1	ERN1	ERN2	ERO1A	ERP27	ERP44	FAF1	FAF2	FAM8A1	FBXO17	FBXO2	FBXO27	FBXO44	FBXO6	FICD	FIS1	FOXRED2	GET4	GORASP2	GSK3B	HERPUD1	HERPUD2	HM13	HSP90B1	HSPA1A	HSPA5	HYOU1	ITPR1	JKAMP	JUN	LOC122513141	MAN1A1	MAN1A2	MAN1B1	MAN1C1	MANF	MAP3K5	MARCHF6	MARCKS	MBTPS1	MBTPS2	NCCRP1	NCK1	NCK2	NFE2L2	NIBAN1	NOD1	NPLOC4	NRBF2	OS9	P4HB	PARP16	PARP6	PARP8	PDIA2	PDIA3	PDIA4	PDIA6	PIK3R1	PIK3R2	PPP1R15A	PPP1R15B	PRKN	PSMC6	PTPN1	QRICH1	RASGRF1	RASGRF2	RCN3	RHBDD1	RHBDD2	RNF103	RNF121	RNF139	RNF145	RNF175	RNF183	RNF185	RNF186	RNF5	RNF7	RPAP2	RTCB	SCAMP5	SEC16A	SEC61B	SEL1L	SEL1L2	SELENOK	SELENOS	SERP1	SERP2	SESN2	SGF29	SGTA	SIRT1	STAT3	STT3B	STUB1	SYVN1	TARDBP	TBL2	THBS1	THBS4	TMBIM4	TMBIM6	TMCO1	TMEM117	TMEM129	TMEM238L	TMEM258	TMEM259	TMEM33	TMEM67	TMTC3	TMTC4	TMUB1	TMUB2	TMX1	TNFRSF10B	TOR1A	TP53	TRAF2	TRIB3	TRIM13	TRIM25	TTC23L	UBA5	UBE2G2	UBE2J1	UBE2J2	UBE4A	UBE4B	UBQLN1	UBQLN2	UBXN10	UBXN4	UBXN6	UBXN8	UFC1	UFD1	UFL1	UFM1	USP19	VAPB	VCP	WFS1	XBP1	YOD1	ZBTB8OS
KE1817_Apoptotic_cell_death_GO:0006915	apoptotic process	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CEACAM5	CEACAM6	CEBPB	CECR2	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FNIP2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA2	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLLN	KMT2A	KREMEN1	KRT20	LALBA	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NISCH	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NUAK2	NUDT2	OGT	OPA1	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNW1	SOD2	SORT1	SPI1	SPIN2B	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1818_Immune_cell_activation_GO:0002263	cell activation involved in immune response	ANXA3	APP	BATF	BTK	C17orf99	CBL	CCL3	CCR6	CD180	CD19	CD1C	CD244	CD40LG	CD74	CDH17	CHGA	CLNK	CORO1A	CPLX2	CX3CR1	DLL1	DNASE1	DNASE1L3	DOCK10	DOCK11	DOCK2	DYSF	EIF2AK4	ENPP3	ENTPD7	EOMES	EXOSC3	EXOSC6	F2RL1	FCER1A	FCER1G	FCGR2B	FCGR3A	GAPT	GATA3	GBF1	GNAI1	GNAQ	GPR15LG	GPR183	GRN	GRP	HAVCR2	HMGB1	HSPD1	ICAM1	IFI35	IFNA10	IFNA14	IFNA16	IFNA17	IFNA2	IFNA21	IFNA4	IFNA5	IFNA6	IFNA7	IFNA8	IFNB1	IFNE	IFNG	IFNK	IFNW1	IL10	IL12B	IL18	IL18R1	IL18RAP	IL1RAP	IL2	IL21	IL33	IL6	IL6R	IL6ST	IRF4	IRF8	ITGAL	JAK1	JMJD1C	KARS1	KIT	KLRF2	KMT2A	LAT	LAT2	LBP	LCP1	LEF1	LFNG	LIG4	LILRA2	LILRB1	LRP1	LY9	LYN	MDK	MEN1	MFNG	MILR1	MRGPRX2	MSH2	MSH6	MTOR	MYB	NBN	NFKBIZ	NKG7	NMI	NOTCH2	NR4A3	PCYT1A	PHF14	PIK3CD	PIK3CG	PLA2G3	PLCG2	PLXNA1	POU2AF1	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB10	PSMB2	PSMB3	PSMB4	PSMB8	PSMB9	PTGDR	PTGDS	PTK2B	PYCARD	RAB44	RAG2	RNF168	RNF8	RORA	RORC	S100A13	SANBR	SBNO2	SCN11A	SEMA4A	SEMA6D	SH2D1B	SLAMF1	SLAMF6	SLC11A1	SLC18A2	SNAP23	SOCS3	SPI1	SPN	ST3GAL1	STAT3	STAT4	STXBP2	STXBP3	SYK	TBX21	TCIM	TMEM98	TNF	TNFSF18	TREM2	TYROBP	VAMP2	VAMP7
KE1819_IFN_signaling_GO:0060333	type II interferon-mediated signaling pathway	CIITA	HCK	IFNG	IFNGR1	IFNGR2	IRF1	JAK1	JAK2	RAF1	SP100	STAT1	TP53	TYK2
KE1820_Immune_mediated_hepatitis_GO:0002384	hepatic immune response	IL6	IL6R
KE1829_Altered_Thyroid_hormone_dependent_gene_expression_GO:0097066	response to thyroid hormone	BRD8	CAB39	CTSB	CTSH	CTSL	CTSS	F7	GBA1	GCLC	GCLM	GHSR	HES1	HPN	INHBB	MED1	RDX	SLC26A5	SLC34A1	THRB	TOMM70
KE1834_Decrease_Acyl_CoA_dehydrogenases_GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ETFA	ETFB	ETFDH	GCDH	IVD
KE1841_Encephalitis_GO:0150076	neuroinflammatory response	ADCY1	ADCY8	ADORA2A	AGER	AIF1	APP	AZU1	C1QA	C5AR1	CLU	CNTF	CX3CL1	CX3CR1	FPR2	GRN	IFNG	IFNGR1	IFNGR2	IL13	IL1RAP	IL33	IL4	ITGAM	ITGB1	ITGB2	JAK2	LRP1	MAPT	NR3C1	PSEN1	SNCA	TLR1	TLR6	TLR9	TNF	TREM2	TYROBP	VPS54	ZEB2
KE1842_Prolonged_TLR9_activation_GO:0034162	toll-like receptor 9 signaling pathway	EPG5	HAVCR2	IRAK1	IRAK4	NR1H4	PIK3AP1	TLR9	TNIP2	UNC93B1
KE1844_systemic_inflammatory_response_syndrome_GO:0006954	inflammatory response	ABCF1	ABHD8	ACER3	ACKR1	ACKR2	ACOD1	ACVR1	ADAM17	ADAM8	ADCY1	ADCY8	ADGRE2	ADGRE5	ADM	ADORA1	ADORA2A	ADORA3	AFAP1L2	AGER	AGR2	AGTR1	AGTR2	AHSG	AIF1	AIM2	AIMP1	ALOX15	ALOX5	ANO6	ANXA1	AOC3	APCS	APIP	APOL2	APOL3	APP	ASS1	ATRN	AZU1	BCL6	BDKRB1	BDKRB2	BIRC2	BIRC3	BLNK	BMP2	BMP6	BMPR1B	BTK	C15orf39	C1QA	C2CD4A	C2CD4B	C3	C3AR1	C4A	C4B	C5	C5AR1	C5AR2	CAMK1D	CAMK4	CAMP	CARD18	CARD8	CASP1	CASP3	CASP4	CASP6	CASP8	CCL1	CCL11	CCL13	CCL14	CCL15	CCL16	CCL17	CCL18	CCL19	CCL2	CCL20	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL3L1	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCRL2	CD14	CD163	CD180	CD36	CD40	CD40LG	CD44	CD47	CD5L	CD6	CD68	CDO1	CEBPB	CELA1	CERS6	CFH	CHI3L1	CHIA	CHST1	CHST2	CHST4	CHUK	CLEC7A	CLU	CMKLR1	CNR2	CNTF	CRH	CRHBP	CRP	CSF1	CSF1R	CTNNBIP1	CUL3	CX3CL1	CX3CR1	CXCL1	CXCL10	CXCL11	CXCL13	CXCL2	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR2	CXCR3	CXCR4	CXCR6	CYBA	CYBB	DAB2IP	DHX9	DPEP1	DPP9	ELANE	ELF3	EPO	F11R	F12	F2	F2R	F2RL1	F3	F8	FADS2	FCER1A	FCER1G	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FFAR2	FFAR3	FFAR4	FN1	FOLR2	FOS	FPR1	FPR2	FPR3	FUT4	FUT7	GATA3	GBP5	GGT5	GPER1	GPR32	GPR32P1	GPR33	GPR68	GRN	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GZMA	GZMB	GZMK	HAVCR2	HBA1	HBB	HCK	HDAC4	HDAC5	HDAC9	HIF1A	HK1	HLA-DRB1	HMGB1	HMGB2	HMOX1	HNRNPA0	HP	HRH1	HRH4	HSPG2	HYAL1	HYAL3	IFI16	IFI27	IFNA2	IFNG	IFNGR1	IFNGR2	IGHE	IGHG1	IKBKB	IKBKG	IL10RB	IL13	IL17A	IL17B	IL17C	IL17D	IL17F	IL17RA	IL17RC	IL17RE	IL18	IL18R1	IL18RAP	IL1A	IL1B	IL1F10	IL1R1	IL1RAP	IL1RL1	IL1RL2	IL1RN	IL20RA	IL22	IL22RA1	IL23A	IL23R	IL25	IL26	IL27	IL2RA	IL33	IL34	IL36A	IL36B	IL36G	IL36RN	IL37	IL4	IL4R	IL5	IL6	IL6R	IL9	INS	IRAK1	IRAK2	IRAK4	IRF5	IRGM	ITCH	ITGAL	ITGAM	ITGB1	ITGB2	ITIH4	JAK2	KDM4D	KDM6B	KIT	KLKB1	KLRG1	KNG1	KRT16	LACC1	LAT	LBP	LCN2	LGALS9	LIAS	LOXL3	LRP1	LTB4R	LXN	LY75	LY86	LY96	LYN	LYZ	MACIR	MAP3K20	MAP3K7	MAPK9	MAPKAPK2	MAPT	MBL2	MDK	MEFV	MEP1B	MFHAS1	MGLL	MIF	MMP25	MRGPRX1	MSMP	MTOR	MYD88	NAIP	NAMPT	NCR3	NDST1	NFAM1	NFATC3	NFATC4	NFKB1	NFKBID	NFKBIZ	NFX1	NINJ1	NKG7	NLRC4	NLRP1	NLRP10	NLRP2	NLRP3	NLRP4	NLRP6	NLRP9	NOD1	NOS2	NOX1	NOX4	NPFF	NR1H4	NR3C1	NR4A1	NRROS	ODAM	OLR1	ORM1	ORM2	PARK7	PARP4	PF4	PF4V1	PIK3CD	PIK3CG	PJA2	PLA2G2A	PLA2G2D	PLA2G2E	PLA2G4B	PLA2G4C	PLD3	PLD4	PLGRKT	PLSCR1	PNMA1	PPBP	PRDX5	PRKCQ	PRKCZ	PRKD1	PRMT2	PROK2	PSEN1	PSTPIP1	PTAFR	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR	PTN	PTX3	PXK	PYCARD	PYDC2	PYDC5	RAC1	RARRES2	REG3A	REG3G	REL	RELA	RELB	RIPK1	RIPK2	RPS6KA4	RPS6KA5	S100A12	S100A8	S100A9	S1PR3	SAA1	SAA2	SAA4	SBNO1	SCG2	SCN11A	SCUBE1	SELE	SEMA7A	SERPINA1	SERPINA3	SERPINF2	SETD4	SIGIRR	SIGLEC1	SLAMF8	SLC11A1	SLC18A2	SMAD1	SMPDL3B	SNAP23	SNCA	SPINK7	STAB1	STAT3	STK39	SYK	TAB2	TAC1	TAC4	TACR1	TBK1	TBX21	TBXA2R	TFRC	TGFB1	THBS1	THEMIS2	TICAM1	TICAM2	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TMIGD3	TNF	TNFAIP3	TNFAIP6	TNFRSF1A	TNFRSF1B	TNFRSF4	TNFSF4	TNIP1	TNIP2	TNIP3	TOLLIP	TRADD	TRAF2	TRAF3IP2	TRAF5	TREM2	TRIL	TRIM14	TRIM21	TRIM31	TSPAN18	TUSC2	TXNIP	TYROBP	USP14	VCAM1	VNN1	VPS54	WNK4	WNT5A	XCL1	XCL2	XCR1	ZBP1	ZC3H12A	ZEB2	ZNF580
KE1848_Toll_Like_Receptor_TLR_Dysregulation_GO:0002224	toll-like receptor signaling pathway	BCL10	BTK	CD274	CD300LF	CTSS	HSPD1	IKBKB	IRAK1	IRAK2	IRAK3	IRAK4	IRF3	LRRC19	LY96	MAP3K7	MAPKAPK2	MAPKAPK3	MYD88	NFKBIZ	PLCG2	PRKCE	RAB11FIP2	REG3G	RELA	RPS6KA3	SCIMP	TICAM1	TICAM2	TIFAB	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TNIP1	TNIP3	TRAF2	TRAF3	TRAF6	UNC93B1
KE1851_Binding_of_agonist_Angiotensin_II_receptor_type_1_receptor_AT1R_GO:0038166	angiotensin-activated signaling pathway	ACE	ACTN2	AGT	AGTR1	AGTR2	AGTRAP	AHCYL1	CA2	CAMK2A	CAV1	MAS1	PLA2G2A	SRC
KE1852_Increased_Ang_II_type_1_receptor_AT1R_GO:0038166	angiotensin-activated signaling pathway	ACE	ACTN2	AGT	AGTR1	AGTR2	AGTRAP	AHCYL1	CA2	CAMK2A	CAV1	MAS1	PLA2G2A	SRC
KE1853_Hyperactivation_of_ACE_Ang_II_AT1R_axis_GO:0002003	angiotensin maturation	ACE	ACE2	ANPEP	ATP6AP2	CMA1	CPA3	CTSG	CTSZ	ENPEP	MME	PRCP	PREP	REN
KE1853_Hyperactivation_of_ACE_Ang_II_AT1R_axis_GO:0038166	angiotensin-activated signaling pathway	ACE	ACTN2	AGT	AGTR1	AGTR2	AGTRAP	AHCYL1	CA2	CAMK2A	CAV1	MAS1	PLA2G2A	SRC
KE1855_Increased_Sodium_sensitive_hypertension_GO:0008217	regulation of blood pressure	ABAT	ACE	ACE2	ACSM3	ACVRL1	ADAMTS16	ADIPOQ	ADM	ADM2	ADM5	ADORA1	ADRA1A	ADRA2B	ADRB1	ADRB2	ADRB3	AGT	AGTR1	AGTR2	AGTRAP	ANPEP	APLN	ATP2B1	ATP6AP2	AVP	AVPR1A	AVPR1B	AVPR2	BDKRB1	BMPR2	BRS3	CALCA	CARTPT	CHGA	CMA1	COL1A2	CORIN	CPA3	CRH	CTSG	CTSZ	CYBA	CYP11B1	CYP11B2	CYP4F2	DDAH1	DLL1	DRD2	DRD3	DRD5	ECE1	EDN1	EDN2	EDN3	EDNRA	EDNRB	EMILIN1	EMILIN2	ENPEP	ERAP1	ERAP2	F2R	F2RL1	FFAR3	GCGR	GCH1	GJA5	GLP1R	GNA11	GNA12	GNA13	GNB3	GPR37L1	GSK3A	HBB	HSD11B2	ID2	KCNK3	KCNQ1	KL	KLK1	KLK2	KLK3	LEP	LNPEP	LRP5	MAS1	MC3R	MME	MRGPRD	MYH6	NMU	NOS1	NOS2	NOS3	NOX1	NPFF	NPPA	NPPB	NPR1	NPR2	NPR3	NPY	NR2F2	NTSR1	OR51E2	OXT	OXTR	P2RX1	P2RX4	PCSK5	PLCB3	POMC	PPARA	PPARG	PRCP	PREP	PTGS1	PTGS2	PTPN1	QRFP	RAMP2	RARRES2	RASL10B	REN	RENBP	RNLS	SCNN1A	SCNN1B	SCNN1D	SCNN1G	SCPEP1	SERPINF2	SGK1	SLC2A5	SMAD3	SNX5	SOD1	SOD2	SPX	TAC1	TAC3	TAC4	TACR1	TACR3	TBXA2R	TNF	TNNI3	TPM1	UCN	UTS2	UTS2B	UTS2R	VEGFC	WNK1	WNK4
KE1857_Platelet_neutrophil_interactions_Increased_GO:0002283	neutrophil activation involved in immune response	ANXA3	DNASE1	DNASE1L3	FCER1G	LILRA2	STXBP2	STXBP3	SYK	TYROBP	VAMP7
KE1897_increased_MyD88_activation_GO:0002755	MyD88-dependent toll-like receptor signaling pathway	BTK	HSPD1	IKBKB	IRAK1	IRAK2	IRAK3	IRAK4	MAP3K7	MYD88	REG3G	TIRAP	TLR4	TLR6	TLR9	TNIP1	TRAF6
KE1899_formation_of_neutrophil_extracellular_traps_NETs_GO:0140645	neutrophil extracellular trap formation	ELANE	MPO	PADI4
KE1900_increased_platelet_surface_TLR9_expression_GO:0034394	protein localization to cell surface	ANGPT1	ANK2	ARF6	CD177	CTNNB1	EMP2	FBLN5	FCN1	FGF10	FGF7	FLNA	GGA1	GGA2	GGA3	GPIHBP1	JAM3	MESD	PLAUR	PRRT1	PTPRK	PTPRU	RIC3	STX4	UNC50	USP4	VCL	VPS54
KE1907_Airway_Surface_Liquid_Height_Decreased_GO:0035377	transepithelial water transport	AQP1	AQP8	CFTR	PKP1	SLC5A1
KE1907_Airway_Surface_Liquid_Height_Decreased_GO:0030321	transepithelial chloride transport	BEST1	CLCN7	CLCNKA	CLCNKB	OSTM1	P2RY4	SLC12A2	SLC26A6
KE1912_Motile_Cilia_Number_Length_Decreased_GO:0044458	motile cilium assembly	AHI1	ARMC12	ARMC2	BBOF1	BBS2	BBS5	CCDC146	CCDC181	CCDC38	CCDC39	CCDC40	CEP128	CFAP157	CFAP206	CFAP221	CFAP43	CFAP44	CFAP47	CFAP53	CFAP54	CFAP58	CFAP61	CFAP65	CFAP69	CFAP97D1	DNAAF1	DNAAF11	DNAAF3	DNAH1	DNAH12	DNAH3	DNALI1	DNHD1	DRC7	DRC9	DYNLL1	DZIP1	E2F4	ENKD1	FOXJ1	FSIP2	GK2	IFT81	KLC3	LRRC46	MCIDAS	MNS1	MYCBPAP	PFN4	RSPH6A	RSPH9	SPAG17	SPAG6	SPATA6	SPEF2	TBC1D21	TPGS1	TTC12	TTLL1	TTLL5	VDAC3	YIF1B	ZMYND10	ZMYND12
KE1917_Altered_gene_expression_NRF2_dependent_antioxidant_pathway_GO:0034599	cellular response to oxidative stress	ABCC1	ABL1	ABL2	ADPRS	AGAP3	AIF1	AIFM1	ALB	ALDH3B1	ANKZF1	APOA4	AQP1	ARNT	ATF2	ATF4	ATM	ATP13A2	ATP7A	BECN1	BMAL1	BNIP3	BRF2	BTK	CAMKK2	CAT	CBX8	CCS	CD36	CDK1	CFL1	CHCHD2	CIAPIN1	CRYGD	CUL1	CUL3	CYGB	CYP1B1	DAPK1	DHRS2	ECT2	EDN1	EDNRA	EIF2S1	ENDOG	ERCC6L2	ERMP1	ERN1	ETV5	FABP1	FANCC	FBXO31	FER	FOS	FOXO1	FOXO3	FXN	FYN	G6PD	GPR37	GPR37L1	GPX1	GPX2	GPX3	GPX4	GPX5	GPX6	GPX7	GPX8	GSR	HDAC2	HDAC6	HIF1A	HM13	HSPA1A	HSPA1B	HTRA2	IL18BP	IL18RAP	IL6	KAT2B	KEAP1	KLF2	KLF4	LCN2	LONP1	LRRK2	MAP1LC3A	MAP2K4	MAP3K5	MAPK13	MAPK7	MAPK8	MAPK9	MAPT	MB	MDM2	MGAT3	MGST1	MMP3	MSRA	MT3	MYB	NDOR1	NET1	NFE2L2	NOS3	NPPA	NQO1	NUDT2	OGG1	OSER1	PAM	PARK7	PARP1	PCNA	PDCD10	PDGFD	PDGFRA	PDK2	PENK	PEX10	PEX12	PEX13	PEX14	PEX2	PEX5	PINK1	PJVK	PKD2	PLA2R1	PLEKHA1	PNPT1	PPARGC1A	PPEF2	PPIA	PPIF	PPP5C	PRDX1	PRDX2	PRDX3	PRDX5	PRKAA1	PRKAA2	PRKCD	PRKD1	PRKN	PRR5L	PTPRK	PXN	PYCR1	PYCR2	PYROXD1	RAD52	RBM11	RBX1	RELA	RHOB	RIPK1	RIPK3	ROMO1	RPS3	SELENOS	SESN2	SETX	SIN3A	SIRPA	SIRT1	SIRT2	SLC25A24	SLC4A11	SNCA	SOD1	SOD2	SOD3	SRC	SRXN1	STAU1	STAU2	STK24	STK25	STK26	STX2	STX4	SUMO4	TBC1D24	TET1	TMEM161A	TNFAIP3	TOP2B	TP53	TPM1	TRPA1	TRPM2	TXN	UCP1	VKORC1L1	VRK2	WNT16	ZC3H12A	ZNF580
KE1921_Altered_gene_expression_NF_kB_dependent_Interleukin_6_pathway_GO:0007249	canonical NF-kappaB signal transduction	ADAM8	BCL3	BIRC2	BIRC3	CARD11	CHUK	CREBBP	EP300	HACD3	IKBKB	IKBKG	IRAK1	IRAK2	IRAK4	MAP3K7	MYD88	NFKB1	NFKB2	NFKBIA	NLRC3	NOD2	NPM1	PRDX4	REL	RELA	RELB	RIPK1	RIPK2	TAB1	TAB2	TAB3	TBK1	TLR7	TLR8	TLR9	TRADD	TRAF6	TRIM8
KE1922_Increased_Reactive_metabolites_production_GO:0006805	xenobiotic metabolic process	AADAC	ABCB1	ABCB11	ABCC1	ABCC2	ABCC3	ABCC4	ABCC5	ABHD10	ACAA1	ACSL1	ACSM1	ACSM2B	ADA	AHR	AHRR	AKR1C1	ALDH2	ALDH3A1	AOC2	AOX1	ARNT	ARNT2	AS3MT	BCHE	BPHL	CAD	CBR1	CBR3	CES2	CES3	CMBL	CRYZ	CYB5B	CYP1A1	CYP1A2	CYP1B1	CYP26A1	CYP26B1	CYP2A13	CYP2A6	CYP2A7	CYP2B6	CYP2C18	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP2D7	CYP2E1	CYP2F1	CYP2J2	CYP2R1	CYP2S1	CYP2U1	CYP2W1	CYP3A4	CYP3A5	CYP3A7	CYP46A1	CYP4F12	CYP4F2	DPYD	EPHX1	FMO2	FMO4	FMO5	GLYAT	GRIN1	GSTA1	GSTA2	GSTA3	GSTA4	GSTA5	GSTM1	GSTM2	GSTM3	GSTM4	GSTO1	GSTO2	GSTP1	GUK1	HEMK2	HNF4A	NAT1	NAT2	NOS1	NQO1	NR1I2	NUDT15	PRKCE	RBBP9	RORA	RORC	S100A12	SLC22A1	SLC22A7	SLC28A2	SLC28A3	SLC29A1	SLC29A3	SLCO1A2	SLCO1B1	SLCO1B3	SLCO2B1	SMOX	SULT1A1	SULT1A2	SULT1A3	SULT1B1	SULT1C3	SULT1C4	SULT2A1	TPMT	UGT1A1	UGT1A10	UGT1A3	UGT1A6	UGT1A7	UGT1A8	UGT1A9	UGT2A1	UGT2A2	UGT2A3	UGT2B11	UGT2B15	UGT2B17	UGT2B4	UGT2B7	UPP2	VKORC1
KE1923_Altered_gene_expression_P53_dependent_apoptosis_pathway_GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	AEN	BAG6	BCL3	BOK	CASP6	CDIP1	DDIT4	DDX5	DYRK2	EP300	FHIT	HINT1	HIPK1	HIPK2	IFI16	JMY	MYBBP1A	PDK2	PHLDA3	PMAIP1	PML	POU4F1	POU4F2	PPP1R13B	PYCARD	RPS27L	RRP8	SIRT1	SNW1	STK11	TMEM109	TP53	TP53BP2	TP63	TP73	URI1	USP28	ZNF385B
KE1941_Memory_Loss_GO:0007613	memory	ABCA7	ABCC8	ACSS2	ADCY8	ADNP	APOE	ARC	ATAD1	ATXN1	ATXN1L	CALB1	CAMK2N1	CAMK4	CEBPB	CHRNA7	CHRNB2	CIC	CPEB3	CREB1	CRH	CUX2	DRD2	EGR1	EIF2AK4	EIF4EBP2	FEN1	FGF13	FOS	FOXO6	GRIA1	HTR2A	INSR	JPH3	KAT2A	KAT2B	KCNK2	KCNK4	KLK8	LCN2	LDLR	LGMN	LRRN4	MAP1A	MAPT	MDK	MUSK	NETO1	NFATC4	NPAS4	NTF4	OXT	PGRMC1	PJA2	PLCB1	PLK2	PPP3CB	PRNP	PSEN1	PTN	RASGRF1	RELN	RGS14	SCN2A	SERPINF1	SGK1	SHANK1	SHANK3	SHISA7	SLC1A1	SLC2A4	SLC6A1	SLC6A4	SLC8A2	SLC8A3	SRF	SYT11	SYT4	TAC1	TACR1	TAFA2	TH	TREM2	TUBA1A	VLDLR	YTHDF1
KE1942_Accumulation_Cytosolic_toxic_Tau_oligomers_GO:1990000	amyloid fibril formation	APP	B2M	BACE1	CAMP	CD36	CDSN	EMD	FKBP1A	FURIN	FUS	GSN	MAPT	MDM2	NAT8	NAT8B	NUP153	PRKN	RIPK1	RIPK3	SERF1A	SIAH1	SIAH2	SNCA	TARDBP	USP9X	VHL
KE1943_Hyperphosphorylation_of_Tau_GO:0006468	protein phosphorylation	AAK1	ABI2	ABL2	ACVR1B	ACVR1C	ADM2	AKT1	ALK	ATF2	ATM	AURKA	AURKC	BCR	BIRC6	BLK	BMX	BRAF	BRSK1	BRSK2	BTK	CAMK2B	CAMK2D	CAMK4	CAMKK2	CCL11	CCL2	CCNE1	CDC25B	CDC42BPA	CDC42BPB	CDC42BPG	CDK1	CDK10	CDK11A	CDK11B	CDK16	CDK17	CDK2	CDK5R1	CDK9	CDKL1	CHEK1	CHEK2	CILK1	CLK2	CLK3	COPS2	COPS8	CREB1	CSF1R	CSK	CSNK1A1	CSNK1D	CSNK1E	CSNK1G2	CSNK2A1	CSNK2A3	CTBP1	DAPK1	DAPK2	DAPK3	DCLK1	DDR1	DDR2	DMPK	DYRK1A	DYRK1B	DYRK2	DYRK3	EEF2K	EFEMP1	EIF2AK1	EIF2AK4	EPHA3	EPHB1	EPHB2	ERBB2	ERBB4	ERG	ERN1	ERN2	FAM20C	FASTK	FER	FES	FGFR1	FGFR2	FGFR4	FGR	FLT1	FLT3	FLT4	FYN	GAS6	GLYCTK	GMFB	GMFG	GSK3B	HASPIN	HCK	HCST	HIPK1	HIPK2	HIPK3	HTATIP2	IFNL4	IGF1R	IGFBP3	IKBKB	IL15	IL21	ILF3	INSR	IP6K3	IRAK1	IRAK2	IRAK3	JAK1	JAK2	JAK3	KALRN	KDR	KIT	LATS1	LATS2	LIMK1	LIMK2	LIPE	LMTK2	LRRK2	LTK	LYN	MAK	MAML1	MAP2K2	MAP3K1	MAP3K11	MAP3K12	MAP3K20	MAP3K21	MAP3K3	MAP3K6	MAP3K7	MAP3K8	MAP3K9	MAP4K1	MAP4K2	MAP4K3	MAP4K4	MAPK1	MAPK10	MAPK15	MAPK3	MAPK4	MAPK6	MAPK8	MAPK9	MAPKAPK5	MARK1	MARK2	MARK3	MARK4	MAST1	MAST2	MATK	MELK	MERTK	MEX3B	MINK1	MKNK1	MKNK2	MORC3	MTOR	MYLK	MYLK2	MYO3A	NEK1	NEK10	NEK11	NEK3	NEK4	NEK6	NEK7	NLK	NTRK1	NTRK2	NUAK1	NUAK2	OXSR1	PAK2	PASK	PCK1	PDGFA	PDGFB	PDGFRA	PDGFRB	PDK3	PDPK1	PEAK1	PHKG2	PIBF1	PICK1	PIK3CD	PIK3R4	PIKFYVE	PIM2	PINK1	PKDCC	PKN1	PKN2	PKN3	PLK1	PLK2	PLK3	PLK4	PPP3CB	PPP4R1	PRDX4	PRKACB	PRKAG1	PRKCA	PRKCB	PRKCD	PRKCH	PRKCI	PRKCZ	PRKD1	PRKD2	PRKD3	PRKDC	PRKX	PRKY	PRLR	PRRT1	PTK2B	PTK6	PTPN6	RAF1	RARA	RNASEL	ROCK1	ROCK2	ROS1	RPS6KA1	RPS6KA4	RPS6KA5	RPS6KB1	RUNX3	SGK1	SGK2	SIK1	SIK2	SIK3	SLK	SMG1	SNRK	SRC	SRMS	SRPK1	SRPK2	STK10	STK11	STK16	STK17A	STK17B	STK24	STK25	STK26	STK3	STK33	STK38	STK38L	STK39	STK4	SYK	TAF1	TAOK3	TBK1	TEC	TESK2	TGFBR1	TLK1	TLK2	TNIK	TNK1	TNKS	TNNI3K	TP53RK	TSSK2	TSSK6	TTBK2	TXK	TYK2	UHMK1	ULK1	ULK2	ULK3	VRK1	VRK2	WNK1	WNK2	WNK3	WNK4	YWHAZ	ZAP70
KE1944_Synaptic_dysfunction_GO:0099536	synaptic signaling	ACHE	ACP1	ADORA1	ADORA2A	AGRN	AKAP5	AKAP9	AKT1	AMPH	ANXA9	AP2B1	APBA1	APBA2	APBA3	APOE	ARRB2	ATXN3	BEGAIN	BEST1	BRSK1	BSN	C1QL1	C1QL2	C1QL3	C1QL4	C1QTNF3	CACNA1A	CACNA1B	CACNA1E	CACNB1	CACNB2	CACNB3	CACNB4	CADPS	CADPS2	CALB2	CARTPT	CBLN1	CBLN2	CBLN3	CBLN4	CDK5	CDK5R1	CEP89	CHAT	CHRDL1	CHRFAM7A	CHRM1	CHRM2	CHRM3	CHRM4	CHRM5	CHRNA1	CHRNA10	CHRNA2	CHRNA3	CHRNA4	CHRNA5	CHRNA6	CHRNA7	CHRNA9	CHRNB1	CHRNB2	CHRNB3	CHRNB4	CHRND	CHRNE	CHRNG	CNIH2	CNIH3	CNP	CNR1	CNR2	COLQ	CORT	CPLX1	CPLX2	CPLX3	CPLX4	CRH	CRHBP	DAG1	DAGLA	DBH	DLG1	DLG2	DLG3	DLG4	DLGAP1	DLGAP2	DMD	DNAJC5	DOC2A	DOC2B	DRD1	DRD2	DRD3	DRD4	DRD5	DRP2	DTNA	DTNB	DVL1	DYTN	EEA1	EFNB3	EFR3A	ELFN1	ELFN2	ERC2	EXOC4	EZH2	F2R	FABP5	FARP1	FCHSD1	FCHSD2	FGF22	GABARAP	GABBR1	GABBR2	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB1	GABRB2	GABRB3	GABRD	GABRE	GABRG1	GABRG2	GABRG3	GABRP	GABRQ	GABRR1	GABRR2	GABRR3	GAD1	GAD2	GALR3	GIPC1	GLRA1	GLRA2	GLRA3	GLRB	GNA11	GNA15	GNAQ	GNB1	GPR176	GRIA1	GRIA2	GRIA3	GRIA4	GRID1	GRID2	GRIK1	GRIK2	GRIK3	GRIK4	GRIK5	GRIN1	GRIN2A	GRIN2B	GRIN2C	GRIN2D	GRIN3A	GRIN3B	GRK2	GRM1	GRM2	GRM3	GRM4	GRM5	GRM6	GRM7	GSK3A	GSK3B	GUCY1A1	HAP1	HAPLN4	HCRT	HCRTR1	HCRTR2	HOMER1	HRH1	HRH2	HRH3	HRH4	HTR1A	HTR1B	HTR1D	HTR1E	HTR1F	HTR2A	HTR2B	HTR2C	HTR3A	HTR3B	HTR3C	HTR3D	HTR3E	HTR4	HTR5A	HTR6	HTR7	IGSF11	IGSF21	IL1RAP	IL1RAPL1	INSYN1	INSYN2A	ITPR1	KCMF1	KCNC4	KCND2	KCND3	KCNIP1	KCNIP2	KCNK2	KCNK3	KCNMB1	KCNMB4	KCNN1	KCNQ2	KCNQ3	KIF1B	KIF5A	KPNA1	LIN7A	LIN7B	LIN7C	LPAR3	LRP6	LRP8	LRRK2	LY6E	LY6G6D	LY6G6E	LY6H	LY6S	LYNX1	LYPD1	MAPK1	MBP	MEF2C	MET	MINK1	MPP2	MPZ	MTNR1B	MYCBPAP	NAPA	NAPB	NEO1	NLGN1	NLGN3	NOS1	NOTCH1	NPAS4	NPBWR1	NPFF	NPPA	NPR2	NPTX1	NPTX2	NPY	NPY5R	NQO1	NR3C1	NRXN1	NRXN2	NSG1	NTRK2	NTSR1	OMP	OPRK1	OPRL1	OPRM1	OTOF	P2RX1	P2RX2	P2RX3	P2RX4	P2RX5	P2RX6	P2RX7	PAFAH1B1	PCDH8	PCDHB10	PCDHB11	PCDHB13	PCDHB14	PCDHB16	PCDHB2	PCDHB3	PCDHB4	PCDHB5	PCDHB6	PCDHB9	PCLO	PDE7B	PDLIM4	PDYN	PDZD11	PENK	PIP5K1C	PLAT	PLCB1	PLG	PLP1	PMCH	PMCHL1	PMCHL2	PMP22	PNOC	PPFIA3	PRKAR1A	PRKAR1B	PRKAR2A	PRKAR2B	PRKCB	PRKCG	PRR7	PRRT2	PSCA	PTCHD1	PTEN	PTPRD	PTPRN2	PTPRS	PVALB	RAB3A	RAB3GAP1	RAB3GAP2	RAPSN	RASD2	RELA	RGS10	RGS8	RIC3	RIMBP2	RIMS1	RIMS2	RIMS3	RIT2	RNF10	RPH3A	RPH3AL	RPS6KA1	RPS6KA2	RPS6KA3	SCN2B	SCRIB	SDCBP	SEPTIN5	SGCE	SGCZ	SHISA6	SLC12A4	SLC12A5	SLC12A6	SLC12A7	SLC17A6	SLC17A7	SLC17A8	SLC18A2	SLC18A3	SLC1A1	SLC1A2	SLC1A3	SLC1A4	SLC1A6	SLC1A7	SLC29A1	SLC32A1	SLC5A7	SLC6A1	SLC6A2	SLC6A3	SLC6A5	SLURP2	SNAP23	SNAP25	SNAP29	SNAP47	SNAPIN	SNCA	SNCB	SNCG	SNPH	SNTA1	SNTG1	SPG11	SSH1	SST	STAC3	STAT3	STX11	STX19	STX1A	STX1B	STX2	STXBP1	STXBP2	STXBP3	SV2A	SV2B	SV2C	SYN1	SYN2	SYN3	SYNJ1	SYPL1	SYT1	SYT10	SYT11	SYT12	SYT13	SYT2	SYT3	SYT4	SYT5	SYT6	SYT7	SYT8	SYT9	TAC1	TENM2	TH	TRPV1	UNC119	UNC13A	UNC13B	UNC13C	UTRN	UTS2	VAMP1	VAMP2	VPS54
KE1945_Dysfunctional_Autophagy_GO:0006914	autophagy	ABI2	ABL1	ACBD5	AFG2B	AMBRA1	ANXA7	AP4M1	ARFIP2	ARHGAP26	ARL8B	ARMC3	ARSB	ATG10	ATG101	ATG12	ATG13	ATG14	ATG16L1	ATG2A	ATG2B	ATG3	ATG4A	ATG4B	ATG4C	ATG4D	ATG5	ATG7	ATG9A	ATG9B	ATM	ATP13A2	ATP2A2	AUP1	BAG3	BCAS3	BCL2	BECN1	BECN2	BNIP3	C19orf12	C9orf72	CALCOCO2	CALM1	CCPG1	CD84	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4BP1	CHMP4C	CHMP5	CHMP6	CHMP7	CISD2	CLEC16A	CLN3	CLTC	CLU	CREG1	CTSK	DAP	DDRGK1	DEPP1	DNAJC16	DNM2	DRAM1	DRAM2	DRD2	EI24	EIF2S1	ELAPOR1	ELAVL1	EMC6	EPG5	EVA1A	FBXL4	FBXO7	FNBP1L	FOXO1	FUNDC1	FUNDC2	GAA	GABARAP	GABARAPL1	GABARAPL2	GABARAPL3	GBA1	GPR137	GPR137B	GRAMD1A	HAP1	HDAC10	HDAC6	HGS	HMGB1	HSP90AA1	HSPA8	IFI16	ILRUN	INHBA	IRF8	IRGM	IRGQ	ITGB4	KLHL3	LAMP2	LGALS8	LIX1	LIX1L	LRBA	LRPPRC	LRRK2	LRSAM1	MAP1LC3A	MAP1LC3B	MAP1LC3B2	MAP1LC3C	MAP1S	MARK2	MFN2	MFSD8	MOAP1	MTMR14	MTMR3	MVB12A	NBR1	NHLRC1	NIPSNAP1	NIPSNAP2	NIPSNAP3A	NIPSNAP3B	NOD2	NPC1	NRBF2	NSFL1C	OGT	OPTN	PACS2	PARK7	PDCD6IP	PEX2	PEX5	PGAM5	PHB2	PHF23	PIK3C3	PIK3CB	PIK3R4	PINK1	PIP4K2A	PIP4K2B	PJVK	PLAA	PLEKHM1	PRKAA1	PRKAA2	PRKN	PSMD14	PTPN22	RAB12	RAB19	RAB1A	RAB1B	RAB1C	RAB23	RAB24	RAB2A	RAB2B	RAB33A	RAB33B	RAB39A	RAB39B	RAB3GAP2	RAB43	RAB7A	RAB8A	RB1CC1	RETREG1	RETREG2	RETREG3	RGS19	RIMOC1	RMC1	RNF166	RNF185	RNF213	RNF41	RTN3	RUBCN	RUBCNL	RUFY4	S100A8	S100A9	SBF2	SCARB2	SEC22B	SEC62	SH3GLB1	SIRT2	SMCR8	SMURF1	SNAP29	SNAP47	SNF8	SNX14	SNX30	SNX7	SPART	SPATA18	SPATA33	SPG11	SQSTM1	SRC	STAM	STAM2	STBD1	STING1	STK11	STUB1	STX12	STX17	STX4	SUPT20H	SYT11	TAX1BP1	TBC1D14	TBC1D17	TBC1D25	TBC1D5	TBK1	TCIRG1	TECPR1	TECPR2	TEX264	TFEB	TIGAR	TIMM23	TM9SF1	TMBIM6	TMEM150B	TMEM208	TMEM39A	TMEM41B	TMEM59	TMEM74	TOLLIP	TOM1	TP53	TP53INP1	TP53INP2	TRAF6	TRAPPC4	TRIM17	TRIM32	TRIM5	TSG101	UBA5	UBQLN1	UBQLN2	UBQLN4	UBXN2A	UBXN2B	UBXN6	UFC1	UFL1	UFM1	ULK1	ULK2	ULK3	USP10	USP13	USP30	UVRAG	VAMP7	VAMP8	VCP	VMP1	VPS11	VPS13A	VPS16	VPS18	VPS25	VPS28	VPS33A	VPS36	VPS37A	VPS37B	VPS37C	VPS37D	VPS39	VPS41	VPS4A	VPS4B	VPS51	VTA1	VTI1A	VTI1B	WDFY3	WDFY4	WDR24	WDR41	WDR45	WDR45B	WDR81	WIPI1	WIPI2	XBP1	YOD1	ZFYVE1	ZFYVE26	ZKSCAN3	ZNF418
KE1978_Increase_risk_microcephaly_GO:0007420	brain development	AATK	ABAT	ABCB6	ACTB	ADGRG1	AFF2	AFG2A	AGTPBP1	AGTR2	AIM2	AKIRIN2	AKNA	ALDH1A2	AMIGO1	AMIGO2	AMIGO3	ANAPC7	APLP1	APOD	AQP1	ARHGAP11B	ARL13B	ARNT2	ASCL1	ATF2	ATF5	ATIC	ATP1A2	ATP1B2	ATP2B4	ATP5PB	ATP5PF	ATP7A	ATXN1	ATXN1L	AVPR1A	AVPR2	BAG6	BASP1	BBS2	BBS4	BGLAP	BMP2	BMP4	BMP5	BMP7	BNIP3	BPTF	BRINP1	BTBD3	C12orf57	CA10	CALM1	CALM2	CALM3	CASP3	CASP5	CBLN1	CCDC14	CCDC141	CCDC85C	CD3E	CDC42	CDH1	CDK5R1	CDK5R2	CDK5RAP1	CDK5RAP2	CDK5RAP3	CDK6	CEND1	CENPF	CEP120	CEP290	CFL1	CHD5	CHD8	CHRNB2	CIC	CITED1	CKB	CLN5	CLP1	CMA1	CNP	CNTN1	CNTN4	CNTN5	CNTNAP2	COL3A1	COL4A1	COQ8B	COX6B1	CRH	CSF1R	CSNK1D	CSNK2A2	CTNNA2	CTNNB1	CTNS	CX3CR1	CXCL12	CXCR4	DAB1	DAB2IP	DCT	DDIT4	DHX37	DISC1	DIXDC1	DLC1	DLL1	DLX2	DMBX1	DNAJB1	DNAJC30	DOCK7	DRAXIN	DRD1	DRD2	DSCAML1	DYNLL1	ECE2	EEF1AKMT4-ECE2	EFHC1	EFNA2	EGR2	EIF2B5	EML1	EMX1	EMX2	EN1	EOMES	EPHA5	EPHA7	EPHB1	EPHB2	EPHB3	ERBB4	EURL	EZH1	EZH2	FAIM2	FAT4	FBXW11	FEZ1	FEZF1	FEZF2	FGF13	FGF8	FGF9	FGFR1	FGFR2	FLNA	FOS	FOXB1	FOXC1	FOXG1	FOXJ1	FOXP1	FOXP2	FOXR1	FUT1	FXR1	FXR2	FZD1	FZD3	FZD4	FZD6	G6PD	GART	GDF10	GHRH	GIT1	GIT2	GLI2	GLUD1	GNB4	GPR158	GRHL2	GRIA1	GRID2	GRIN1	GRIN2A	GRIN2B	GRIN2C	GRIN2D	GSK3B	GSX1	GSX2	H2BC12L	HAP1	HES1	HES5	HESX1	HNRNPD	HOOK3	HSD17B7	HSPA5	HSPG2	HTR5A	HTR6	ID2	IER3IP1	INA	INHBA	INHBB	ITGAM	JHY	KCNA1	KCNA2	KCNC1	KCNC2	KCNE1	KDM1A	KDM2B	KDM4B	KDM6B	KDM7A	KIF14	KIF26A	KIRREL3	KNDC1	LAMB1	LHX1	LHX6	LHX8	LMX1A	LPAR1	LRP6	LRP8	LRRK2	MACO1	MACROD2	MACROH2A2	MAOB	MAP1S	MAPKAP1	MAST1	MATCAP1	MBOAT7	MCPH1	MDGA1	MDK	MEIS1	MEIS2	MEIS3	MEIS3P1	MEIS3P2	METTL14	METTL3	MFSD2A	MGARP	MINK1	MKKS	MT-CO1	MT-ND4	MYO16	NARS1	NAV2	NCAPG2	NCAPH2	NCOA1	NCOA6	NCOR2	NCSTN	NDE1	NDEL1	NDNF	NDRG2	NDUFS3	NDUFS4	NEFL	NES	NEUROD1	NEUROD2	NEUROG1	NEUROG2	NEUROG3	NF1	NFASC	NFIB	NIPBL	NKX2-1	NKX2-2	NKX2-6	NLGN4X	NNAT	NOG	NOTCH2NLA	NOTCH2NLB	NOTCH2NLC	NOTO	NPY	NR0B1	NR4A2	NRCAM	NRG1	NRGN	NRP1	NRP2	NSUN5	NTRK2	NUMB	NUMBL	OGDH	OPHN1	OTX1	OTX2	P2RY12	PADI2	PAFAH1B1	PAK1	PALS1	PAX2	PAX4	PAX6	PBX1	PBX2	PBX3	PBX4	PCDH18	PCDH9	PCM1	PDSS2	PEX13	PHACTR1	PHF8	PHGDH	PHLPP2	PHOX2B	PITX2	PITX3	PLCB1	PLP1	PLXNA1	PLXNA3	PLXNA4	PLXNB2	POMK	POTEE	POU1F1	POU3F1	POU3F2	POU3F3	POU3F4	POU6F1	PPP1R9B	PPT1	PRDM13	PROP1	PROX1	PSEN1	PTBP2	PTCH1	PTCHD1	PTEN	PTF1A	PTPN11	QARS1	RAB18	RAB3GAP1	RAC1	RAD1	RAN	RAPGEF2	RARA	RBBP4	RBBP7	RELN	RHOA	ROBO1	ROBO2	ROBO3	ROGDI	RORA	RTN1	RTN2	RTN3	RTN4	RTN4R	RTN4RL1	RTN4RL2	RYK	S100A1	SALL1	SALL3	SCN5A	SCT	SCYL2	SDF4	SEC16A	SEMA3A	SEMA3D	SEMA3E	SEMA3G	SEMA4C	SEMA5A	SEMA6B	SETD1A	SEZ6	SEZ6L	SEZ6L2	SHANK3	SHH	SHROOM2	SHROOM4	SIN3A	SIRT2	SIX3	SKI	SLC1A1	SLC23A1	SLC2A1	SLC32A1	SLC38A2	SLC6A17	SLC6A4	SLC8A3	SLIT1	SLIT2	SMARCA1	SMC2	SMC4	SMG9	SMO	SOCS7	SOX1	SOX11	SOX12	SOX14	SOX15	SOX2	SOX21	SOX3	SOX4	SOX6	SPEF2	SRD5A1	SRD5A2	SRGAP2	SRGAP2C	SSBP3	SSTR1	STIL	SUDS3	SUN1	SUN2	SYNE2	SYNGR3	SYPL2	SZT2	TACC1	TACC2	TACC3	TAF1	TBC1D23	TBR1	TGFBR2	TMEM108	TMEM14B	TMX2	TOX	TRAPPC9	TRNP1	TSKU	TTBK1	TTBK2	TUBA1A	TUBB2A	TUBB2B	TUBGCP2	TYRO3	TYROBP	UBE3A	UCHL5	UFC1	UFM1	UGP2	UNC5C	UQCRQ	UTP3	VAX1	VAX2	VCX	VCX2	VCX3A	VCX3B	VCY	VPS51	WDR62	WHRN	WLS	WNT1	WNT2	WNT2B	WNT3	WNT3A	WNT5A	WNT7A	WNT7B	WNT9B	XAB2	XRN2	YWHAE	YWHAH	YWHAQ	ZDHHC16	ZIC1	ZIC2	ZIC3	ZMIZ1	ZNF148	ZNF335	ZNF365	ZNF430	ZSWIM6
KE2005_Altered_neurotransmission_in_development_GO:0007268	chemical synaptic transmission	ACHE	ACP1	ADORA1	ADORA2A	AGRN	AKAP5	AKAP9	AKT1	AMPH	ANXA9	AP2B1	APBA1	APBA2	APBA3	APOE	ARRB2	ATXN3	BEGAIN	BEST1	BRSK1	BSN	CACNA1A	CACNA1B	CACNA1E	CACNB1	CACNB2	CACNB3	CACNB4	CADPS	CADPS2	CARTPT	CBLN1	CBLN2	CDK5	CEP89	CHAT	CHRDL1	CHRFAM7A	CHRM1	CHRM2	CHRM3	CHRM4	CHRM5	CHRNA1	CHRNA10	CHRNA2	CHRNA3	CHRNA4	CHRNA5	CHRNA6	CHRNA7	CHRNA9	CHRNB1	CHRNB2	CHRNB3	CHRNB4	CHRND	CHRNE	CHRNG	CNIH2	CNIH3	CNP	COLQ	CORT	CPLX1	CPLX2	CPLX3	CPLX4	CRH	CRHBP	DBH	DLG1	DLG2	DLG3	DLG4	DLGAP1	DLGAP2	DNAJC5	DOC2A	DOC2B	DRD1	DRD2	DRD3	DRD4	DRD5	DTNA	DVL1	EEA1	EFR3A	ELFN1	ELFN2	ERC2	EXOC4	EZH2	FCHSD1	FCHSD2	GABARAP	GABBR1	GABBR2	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB1	GABRB2	GABRB3	GABRD	GABRE	GABRG1	GABRG2	GABRG3	GABRP	GABRQ	GABRR1	GABRR2	GABRR3	GAD1	GAD2	GALR3	GIPC1	GLRA1	GLRA2	GLRA3	GLRB	GPR176	GRIA1	GRIA2	GRIA3	GRIA4	GRID1	GRID2	GRIK1	GRIK2	GRIK3	GRIK4	GRIK5	GRIN1	GRIN2A	GRIN2B	GRIN2C	GRIN2D	GRIN3A	GRIN3B	GRM1	GRM2	GRM3	GRM4	GRM5	GRM6	GRM7	GSK3A	GSK3B	HAP1	HAPLN4	HCRT	HCRTR1	HCRTR2	HOMER1	HRH1	HRH2	HRH3	HRH4	HTR1A	HTR1B	HTR1D	HTR1E	HTR1F	HTR2A	HTR2B	HTR2C	HTR3A	HTR3B	HTR3C	HTR3D	HTR3E	HTR4	HTR5A	HTR6	HTR7	INSYN1	INSYN2A	KCNC4	KCND2	KCND3	KCNIP1	KCNIP2	KCNK2	KCNK3	KCNMB1	KCNMB4	KCNN1	KCNQ2	KCNQ3	KIF1B	KIF5A	LIN7A	LIN7B	LIN7C	LPAR3	LRP6	LRP8	LRRK2	MAPK1	MBP	MEF2C	MET	MINK1	MPP2	MPZ	MTNR1B	MYCBPAP	NAPA	NAPB	NLGN1	NLGN3	NOTCH1	NPAS4	NPBWR1	NPFF	NPR2	NPTX1	NPTX2	NPY	NPY5R	NQO1	NR3C1	NRXN1	NRXN2	NSG1	NTSR1	OMP	OPRK1	OPRL1	OTOF	P2RX1	P2RX2	P2RX3	P2RX4	P2RX5	P2RX6	P2RX7	PAFAH1B1	PCDH8	PCDHB10	PCDHB11	PCDHB13	PCDHB14	PCDHB16	PCDHB2	PCDHB3	PCDHB4	PCDHB5	PCDHB6	PCDHB9	PCLO	PDE7B	PDLIM4	PDYN	PDZD11	PENK	PIP5K1C	PLP1	PMCH	PMCHL1	PMCHL2	PMP22	PNOC	PPFIA3	PRKAR1A	PRKAR1B	PRKAR2A	PRKAR2B	PRKCG	PRRT2	PTCHD1	PTEN	PTPRN2	PVALB	RAB3A	RAB3GAP1	RAPSN	RASD2	RIC3	RIMBP2	RIMS1	RIMS2	RIMS3	RIT2	RPH3A	RPH3AL	RPS6KA1	RPS6KA2	RPS6KA3	SCN2B	SCRIB	SDCBP	SEPTIN5	SHISA6	SLC12A4	SLC12A5	SLC12A6	SLC12A7	SLC17A6	SLC17A7	SLC17A8	SLC18A2	SLC18A3	SLC1A1	SLC1A2	SLC1A3	SLC1A4	SLC1A6	SLC1A7	SLC29A1	SLC32A1	SLC5A7	SLC6A1	SLC6A2	SLC6A3	SLC6A5	SNAP23	SNAP25	SNAP29	SNAP47	SNAPIN	SNCA	SNCB	SNCG	SNPH	SPG11	SSH1	SST	STAC3	STX11	STX19	STX1A	STX1B	STX2	STXBP1	STXBP2	STXBP3	SV2A	SV2B	SV2C	SYN1	SYN2	SYN3	SYNJ1	SYPL1	SYT1	SYT10	SYT11	SYT12	SYT13	SYT2	SYT3	SYT4	SYT5	SYT6	SYT7	SYT8	SYT9	TAC1	TH	TRPV1	UNC119	UNC13A	UNC13B	UNC13C	UTS2	VAMP1	VAMP2	VPS54
KE2007_Non_coding_RNA_expression_profile_alteration_GO:0070918	regulatory ncRNA processing	ADAR	AGO1	AGO2	AGO3	AGO4	BCDIN3D	DDX4	DDX5	DGCR8	DICER1	DROSHA	EXD1	FKBP6	GPAT2	GTSF1	HENMT1	HNRNPA2B1	LIN28A	LIN28B	MAEL	METTL14	METTL3	MOV10L1	NCBP1	NCBP2	PARN	PIWIL1	PIWIL2	PIWIL3	PIWIL4	PLD6	PNLDC1	PRKRA	PUM1	PUM2	PUS10	SMAD1	SMAD2	SMAD3	SNIP1	SPOUT1	SRRT	SRSF3	TARBP2	TDRD1	TDRD12	TDRD6	TDRD7	TDRD9	TDRKH	TERT	TNRC6A	TNRC6B	TRIM71	TSN	TSNAX	TUT4	TUT7	ZC3H7A	ZC3H7B
KE2009_Activation_of_inflammation_pathway_GO:0006954	inflammatory response	ABCF1	ABHD8	ACER3	ACKR1	ACKR2	ACOD1	ACVR1	ADAM17	ADAM8	ADCY1	ADCY8	ADGRE2	ADGRE5	ADM	ADORA1	ADORA2A	ADORA3	AFAP1L2	AGER	AGR2	AGTR1	AGTR2	AHSG	AIF1	AIM2	AIMP1	ALOX15	ALOX5	ANO6	ANXA1	AOC3	APCS	APIP	APOL2	APOL3	APP	ASS1	ATRN	AZU1	BCL6	BDKRB1	BDKRB2	BIRC2	BIRC3	BLNK	BMP2	BMP6	BMPR1B	BTK	C15orf39	C1QA	C2CD4A	C2CD4B	C3	C3AR1	C4A	C4B	C5	C5AR1	C5AR2	CAMK1D	CAMK4	CAMP	CARD18	CARD8	CASP1	CASP3	CASP4	CASP6	CASP8	CCL1	CCL11	CCL13	CCL14	CCL15	CCL16	CCL17	CCL18	CCL19	CCL2	CCL20	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL3L1	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCRL2	CD14	CD163	CD180	CD36	CD40	CD40LG	CD44	CD47	CD5L	CD6	CD68	CDO1	CEBPB	CELA1	CERS6	CFH	CHI3L1	CHIA	CHST1	CHST2	CHST4	CHUK	CLEC7A	CLU	CMKLR1	CNR2	CNTF	CRH	CRHBP	CRP	CSF1	CSF1R	CTNNBIP1	CUL3	CX3CL1	CX3CR1	CXCL1	CXCL10	CXCL11	CXCL13	CXCL2	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR2	CXCR3	CXCR4	CXCR6	CYBA	CYBB	DAB2IP	DHX9	DPEP1	DPP9	ELANE	ELF3	EPO	F11R	F12	F2	F2R	F2RL1	F3	F8	FADS2	FCER1A	FCER1G	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FFAR2	FFAR3	FFAR4	FN1	FOLR2	FOS	FPR1	FPR2	FPR3	FUT4	FUT7	GATA3	GBP5	GGT5	GPER1	GPR32	GPR32P1	GPR33	GPR68	GRN	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GZMA	GZMB	GZMK	HAVCR2	HBA1	HBB	HCK	HDAC4	HDAC5	HDAC9	HIF1A	HK1	HLA-DRB1	HMGB1	HMGB2	HMOX1	HNRNPA0	HP	HRH1	HRH4	HSPG2	HYAL1	HYAL3	IFI16	IFI27	IFNA2	IFNG	IFNGR1	IFNGR2	IGHE	IGHG1	IKBKB	IKBKG	IL10RB	IL13	IL17A	IL17B	IL17C	IL17D	IL17F	IL17RA	IL17RC	IL17RE	IL18	IL18R1	IL18RAP	IL1A	IL1B	IL1F10	IL1R1	IL1RAP	IL1RL1	IL1RL2	IL1RN	IL20RA	IL22	IL22RA1	IL23A	IL23R	IL25	IL26	IL27	IL2RA	IL33	IL34	IL36A	IL36B	IL36G	IL36RN	IL37	IL4	IL4R	IL5	IL6	IL6R	IL9	INS	IRAK1	IRAK2	IRAK4	IRF5	IRGM	ITCH	ITGAL	ITGAM	ITGB1	ITGB2	ITIH4	JAK2	KDM4D	KDM6B	KIT	KLKB1	KLRG1	KNG1	KRT16	LACC1	LAT	LBP	LCN2	LGALS9	LIAS	LOXL3	LRP1	LTB4R	LXN	LY75	LY86	LY96	LYN	LYZ	MACIR	MAP3K20	MAP3K7	MAPK9	MAPKAPK2	MAPT	MBL2	MDK	MEFV	MEP1B	MFHAS1	MGLL	MIF	MMP25	MRGPRX1	MSMP	MTOR	MYD88	NAIP	NAMPT	NCR3	NDST1	NFAM1	NFATC3	NFATC4	NFKB1	NFKBID	NFKBIZ	NFX1	NINJ1	NKG7	NLRC4	NLRP1	NLRP10	NLRP2	NLRP3	NLRP4	NLRP6	NLRP9	NOD1	NOS2	NOX1	NOX4	NPFF	NR1H4	NR3C1	NR4A1	NRROS	ODAM	OLR1	ORM1	ORM2	PARK7	PARP4	PF4	PF4V1	PIK3CD	PIK3CG	PJA2	PLA2G2A	PLA2G2D	PLA2G2E	PLA2G4B	PLA2G4C	PLD3	PLD4	PLGRKT	PLSCR1	PNMA1	PPBP	PRDX5	PRKCQ	PRKCZ	PRKD1	PRMT2	PROK2	PSEN1	PSTPIP1	PTAFR	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR	PTN	PTX3	PXK	PYCARD	PYDC2	PYDC5	RAC1	RARRES2	REG3A	REG3G	REL	RELA	RELB	RIPK1	RIPK2	RPS6KA4	RPS6KA5	S100A12	S100A8	S100A9	S1PR3	SAA1	SAA2	SAA4	SBNO1	SCG2	SCN11A	SCUBE1	SELE	SEMA7A	SERPINA1	SERPINA3	SERPINF2	SETD4	SIGIRR	SIGLEC1	SLAMF8	SLC11A1	SLC18A2	SMAD1	SMPDL3B	SNAP23	SNCA	SPINK7	STAB1	STAT3	STK39	SYK	TAB2	TAC1	TAC4	TACR1	TBK1	TBX21	TBXA2R	TFRC	TGFB1	THBS1	THEMIS2	TICAM1	TICAM2	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TMIGD3	TNF	TNFAIP3	TNFAIP6	TNFRSF1A	TNFRSF1B	TNFRSF4	TNFSF4	TNIP1	TNIP2	TNIP3	TOLLIP	TRADD	TRAF2	TRAF3IP2	TRAF5	TREM2	TRIL	TRIM14	TRIM21	TRIM31	TSPAN18	TUSC2	TXNIP	TYROBP	USP14	VCAM1	VNN1	VPS54	WNK4	WNT5A	XCL1	XCL2	XCR1	ZBP1	ZC3H12A	ZEB2	ZNF580
KE2010_Pulmonary_inflammation_GO:0006954	inflammatory response	ABCF1	ABHD8	ACER3	ACKR1	ACKR2	ACOD1	ACVR1	ADAM17	ADAM8	ADCY1	ADCY8	ADGRE2	ADGRE5	ADM	ADORA1	ADORA2A	ADORA3	AFAP1L2	AGER	AGR2	AGTR1	AGTR2	AHSG	AIF1	AIM2	AIMP1	ALOX15	ALOX5	ANO6	ANXA1	AOC3	APCS	APIP	APOL2	APOL3	APP	ASS1	ATRN	AZU1	BCL6	BDKRB1	BDKRB2	BIRC2	BIRC3	BLNK	BMP2	BMP6	BMPR1B	BTK	C15orf39	C1QA	C2CD4A	C2CD4B	C3	C3AR1	C4A	C4B	C5	C5AR1	C5AR2	CAMK1D	CAMK4	CAMP	CARD18	CARD8	CASP1	CASP3	CASP4	CASP6	CASP8	CCL1	CCL11	CCL13	CCL14	CCL15	CCL16	CCL17	CCL18	CCL19	CCL2	CCL20	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL3L1	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCRL2	CD14	CD163	CD180	CD36	CD40	CD40LG	CD44	CD47	CD5L	CD6	CD68	CDO1	CEBPB	CELA1	CERS6	CFH	CHI3L1	CHIA	CHST1	CHST2	CHST4	CHUK	CLEC7A	CLU	CMKLR1	CNR2	CNTF	CRH	CRHBP	CRP	CSF1	CSF1R	CTNNBIP1	CUL3	CX3CL1	CX3CR1	CXCL1	CXCL10	CXCL11	CXCL13	CXCL2	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR2	CXCR3	CXCR4	CXCR6	CYBA	CYBB	DAB2IP	DHX9	DPEP1	DPP9	ELANE	ELF3	EPO	F11R	F12	F2	F2R	F2RL1	F3	F8	FADS2	FCER1A	FCER1G	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FFAR2	FFAR3	FFAR4	FN1	FOLR2	FOS	FPR1	FPR2	FPR3	FUT4	FUT7	GATA3	GBP5	GGT5	GPER1	GPR32	GPR32P1	GPR33	GPR68	GRN	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GZMA	GZMB	GZMK	HAVCR2	HBA1	HBB	HCK	HDAC4	HDAC5	HDAC9	HIF1A	HK1	HLA-DRB1	HMGB1	HMGB2	HMOX1	HNRNPA0	HP	HRH1	HRH4	HSPG2	HYAL1	HYAL3	IFI16	IFI27	IFNA2	IFNG	IFNGR1	IFNGR2	IGHE	IGHG1	IKBKB	IKBKG	IL10RB	IL13	IL17A	IL17B	IL17C	IL17D	IL17F	IL17RA	IL17RC	IL17RE	IL18	IL18R1	IL18RAP	IL1A	IL1B	IL1F10	IL1R1	IL1RAP	IL1RL1	IL1RL2	IL1RN	IL20RA	IL22	IL22RA1	IL23A	IL23R	IL25	IL26	IL27	IL2RA	IL33	IL34	IL36A	IL36B	IL36G	IL36RN	IL37	IL4	IL4R	IL5	IL6	IL6R	IL9	INS	IRAK1	IRAK2	IRAK4	IRF5	IRGM	ITCH	ITGAL	ITGAM	ITGB1	ITGB2	ITIH4	JAK2	KDM4D	KDM6B	KIT	KLKB1	KLRG1	KNG1	KRT16	LACC1	LAT	LBP	LCN2	LGALS9	LIAS	LOXL3	LRP1	LTB4R	LXN	LY75	LY86	LY96	LYN	LYZ	MACIR	MAP3K20	MAP3K7	MAPK9	MAPKAPK2	MAPT	MBL2	MDK	MEFV	MEP1B	MFHAS1	MGLL	MIF	MMP25	MRGPRX1	MSMP	MTOR	MYD88	NAIP	NAMPT	NCR3	NDST1	NFAM1	NFATC3	NFATC4	NFKB1	NFKBID	NFKBIZ	NFX1	NINJ1	NKG7	NLRC4	NLRP1	NLRP10	NLRP2	NLRP3	NLRP4	NLRP6	NLRP9	NOD1	NOS2	NOX1	NOX4	NPFF	NR1H4	NR3C1	NR4A1	NRROS	ODAM	OLR1	ORM1	ORM2	PARK7	PARP4	PF4	PF4V1	PIK3CD	PIK3CG	PJA2	PLA2G2A	PLA2G2D	PLA2G2E	PLA2G4B	PLA2G4C	PLD3	PLD4	PLGRKT	PLSCR1	PNMA1	PPBP	PRDX5	PRKCQ	PRKCZ	PRKD1	PRMT2	PROK2	PSEN1	PSTPIP1	PTAFR	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR	PTN	PTX3	PXK	PYCARD	PYDC2	PYDC5	RAC1	RARRES2	REG3A	REG3G	REL	RELA	RELB	RIPK1	RIPK2	RPS6KA4	RPS6KA5	S100A12	S100A8	S100A9	S1PR3	SAA1	SAA2	SAA4	SBNO1	SCG2	SCN11A	SCUBE1	SELE	SEMA7A	SERPINA1	SERPINA3	SERPINF2	SETD4	SIGIRR	SIGLEC1	SLAMF8	SLC11A1	SLC18A2	SMAD1	SMPDL3B	SNAP23	SNCA	SPINK7	STAB1	STAT3	STK39	SYK	TAB2	TAC1	TAC4	TACR1	TBK1	TBX21	TBXA2R	TFRC	TGFB1	THBS1	THEMIS2	TICAM1	TICAM2	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TMIGD3	TNF	TNFAIP3	TNFAIP6	TNFRSF1A	TNFRSF1B	TNFRSF4	TNFSF4	TNIP1	TNIP2	TNIP3	TOLLIP	TRADD	TRAF2	TRAF3IP2	TRAF5	TREM2	TRIL	TRIM14	TRIM21	TRIM31	TSPAN18	TUSC2	TXNIP	TYROBP	USP14	VCAM1	VNN1	VPS54	WNK4	WNT5A	XCL1	XCL2	XCR1	ZBP1	ZC3H12A	ZEB2	ZNF580
KE2012_Fibroblast_proliferation_and_differentiation_GO:0048144	fibroblast proliferation	COL3A1	WNT7B	ZNF416
KE2012_Fibroblast_proliferation_and_differentiation_GO:0048762	mesenchymal cell differentiation	AKNA	AMELX	ARB2A	BMP2	BMP7	CDC42	CDH2	CORO1C	CTNNB1	CUL1	CUL7	CYP26C1	DDX17	DDX5	DLG5	EDN1	EDNRA	EFNA1	ENG	EOMES	EPB41L5	ERBB4	FAM83D	FBXL17	FGF12	FGF8	FGFR1	FGFR2	FN1	FOLR1	FOXC1	FOXF2	FRZB	GDNF	GFAP	GSC	GSK3B	HAND2	HAS2	HEY1	HEY2	HEYL	HGF	HIF1A	HMGA2	HNRNPAB	HTR2B	IGF1	ISL1	JAG1	KBTBD8	KLHL12	LEF1	LOXL2	LOXL3	LRP6	MEF2C	MSX1	NCAM1	NOG	NOLC1	NOTCH1	NOTCH4	NRG1	NRP1	NRP2	NRTN	OLFM1	OSR1	OTUD5	PAX2	PDCD4	PDCD6	PEF1	PHACTR4	PHOX2B	PITX2	POLR1B	RADIL	RANBP3L	RBPJ	RBX1	ROCK1	ROCK2	S100A4	SEMA3A	SEMA3B	SEMA3C	SEMA3D	SEMA3E	SEMA3F	SEMA3G	SEMA4A	SEMA4B	SEMA4C	SEMA4D	SEMA4F	SEMA4G	SEMA5A	SEMA5B	SEMA6A	SEMA6B	SEMA6C	SEMA6D	SEMA7A	SHH	SIX1	SIX2	SKP1	SLC39A10	SLC39A6	SMAD4	SNAI1	SNAI2	SOX10	SOX8	SOX9	SP6	SPRY1	STAT1	TAPT1	TASOR	TBX1	TBX20	TBX3	TCF21	TCOF1	TGFB1	TGFB2	TGFBR1	TGFBR2	TGFBR3	TGFBR3L	TRIM28	WNT4	WNT5A	WNT8A	ZFP64
KE2013_Airway_remodeling_GO:0048771	tissue remodeling	ACE	ACP5	ACVR2B	ACVRL1	AGT	AGTR2	ATP7A	BGN	BMPR2	CAV1	CCR2	CSPG4	CYP1A1	DLL4	EDNRA	EFNA2	ELF3	EPAS1	EPHA2	F2R	GDF5	GJA1	GPR55	HIF1A	HTR1B	IL23A	IL7	LGR4	MEF2C	MMP14	MMP2	NFKB1	NOL3	NOS3	NOTCH2	NPPC	NPR2	NPR3	P3H4	PLG	PTH	PTK2B	PTN	RAB3D	RAB7A	RAC2	RBPJ	RSPO3	SPP2	SRC	TGFB1	THBS4	TIE1	TPP1	TRAF6	ZNF675
KE2017_Endoplasmic_reticulum_stress_GO:0034976	response to endoplasmic reticulum stress	AATF	ABL1	AFG2B	AGR2	AIFM1	ALOX15	AMFR	ANKS4B	ANKZF1	APAF1	ASB11	ATF3	ATF4	ATF6	ATF6B	ATG10	ATP2A1	ATP2A2	ATP2A3	AUP1	BAG6	BAK1	BAX	BBC3	BCAP31	BCL2	BCL2L11	BHLHA15	BRSK2	CALR	CALR3	CANX	CASP4	CCDC47	CDK5RAP3	CEBPB	CFTR	CHAC1	CLGN	CREB3	CREB3L1	CREB3L2	CREB3L3	CREBZF	CTH	CXCL8	DAB2IP	DDIT3	DDRGK1	DDX3X	DERL1	DERL2	DERL3	DNAJB12	DNAJB9	DNAJC10	DNAJC3	ECPAS	EDEM1	EDEM2	EDEM3	EEF2	EIF2AK3	EIF2B5	EIF2S1	EIF4G1	ERLEC1	ERLIN1	ERLIN2	ERMP1	ERN1	ERN2	ERO1A	ERP27	ERP44	FAF1	FAF2	FAM8A1	FBXO17	FBXO2	FBXO27	FBXO44	FBXO6	FICD	FIS1	FOXRED2	GET4	GORASP2	GSK3B	HERPUD1	HERPUD2	HM13	HSP90B1	HSPA1A	HSPA5	HYOU1	ITPR1	JKAMP	JUN	LOC122513141	MAN1A1	MAN1A2	MAN1B1	MAN1C1	MANF	MAP3K5	MARCHF6	MARCKS	MBTPS1	MBTPS2	NCCRP1	NCK1	NCK2	NFE2L2	NIBAN1	NOD1	NPLOC4	NRBF2	OS9	P4HB	PARP16	PARP6	PARP8	PDIA2	PDIA3	PDIA4	PDIA6	PIK3R1	PIK3R2	PPP1R15A	PPP1R15B	PRKN	PSMC6	PTPN1	QRICH1	RASGRF1	RASGRF2	RCN3	RHBDD1	RHBDD2	RNF103	RNF121	RNF139	RNF145	RNF175	RNF183	RNF185	RNF186	RNF5	RNF7	RPAP2	RTCB	SCAMP5	SEC16A	SEC61B	SEL1L	SEL1L2	SELENOK	SELENOS	SERP1	SERP2	SESN2	SGF29	SGTA	SIRT1	STAT3	STT3B	STUB1	SYVN1	TARDBP	TBL2	THBS1	THBS4	TMBIM4	TMBIM6	TMCO1	TMEM117	TMEM129	TMEM238L	TMEM258	TMEM259	TMEM33	TMEM67	TMTC3	TMTC4	TMUB1	TMUB2	TMX1	TNFRSF10B	TOR1A	TP53	TRAF2	TRIB3	TRIM13	TRIM25	TTC23L	UBA5	UBE2G2	UBE2J1	UBE2J2	UBE4A	UBE4B	UBQLN1	UBQLN2	UBXN10	UBXN4	UBXN6	UBXN8	UFC1	UFD1	UFL1	UFM1	USP19	VAPB	VCP	WFS1	XBP1	YOD1	ZBTB8OS
KE2029_protein_coupled_estrogen_receptor_1_GPER_activation_GO:0030520	estrogen receptor signaling pathway	AR	CCDC62	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	NCOA1	NCOA4	PADI2	POU4F2	PPARGC1B	RBFOX2	SAFB	TADA3	TRIP4
KE2030_Activation_PARP1_GO:0070212	protein poly-ADP-ribosylation	PARP1	PARP10	PARP14	PARP15	PARP2	TNKS	TNKS2
KE2031_Releasing_Apoptosis_Inducing_Factor_AIF_GO:0097190	apoptotic signaling pathway	ABL1	ACVR1B	ACVR1C	ADORA1	AEN	AIFM1	ANXA6	APAF1	ARL6IP5	ATF2	ATF4	ATM	ATP2A1	ATP2A3	BAD	BAG3	BAG6	BAK1	BAX	BBC3	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L2	BCL3	BID	BIRC2	BIRC3	BLOC1S2	BNIP3	BNIP3L	BOK	BRCA1	BRSK2	BTK	CARD8	CARD9	CASP2	CASP3	CASP4	CASP6	CASP8	CASP8AP2	CASP9	CAV1	CD24	CD27	CD38	CD70	CDIP1	CDKN1A	CEBPB	CFLAR	CHAC1	CHEK2	CIB1	CIDEB	CLEC7A	CLU	COA8	CRADD	CRH	CRIP1	CUL1	CUL2	CUL3	CUL4A	CUL5	CYCS	CYP1B1	DAB2IP	DAP	DAP3	DAPK1	DAPL1	DAXX	DDIT3	DDIT4	DDX3X	DDX47	DDX5	DEDD	DEDD2	DELE1	DIABLO	DIDO1	DNAJC10	DPF2	DYRK2	E2F1	EP300	EPHA2	ERBB3	ERN1	ERN2	ERO1A	FADD	FAS	FASLG	FASTK	FGFR3	FHIT	FNIP2	FZD9	G0S2	GABARAP	GGCT	GSK3A	GSK3B	GSKIP	HIC1	HINT1	HIP1	HIP1R	HIPK1	HIPK2	HSPE1	HTRA2	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFNG	IKBKE	IL12A	IL6R	INHBA	ITGAV	ITPR1	JAK2	JMY	LAPTM5	LGALS12	LOC122513141	MAP2K4	MAP3K5	MCL1	MLLT11	MOAP1	MSH6	MYBBP1A	NFKBIZ	NGF	NGFR	NLRP1	NODAL	NOL3	P2RX4	P2RX7	PAWR	PDCD10	PDCD6	PDE3A	PDK1	PDK2	PDPK1	PHLDA3	PMAIP1	PML	POU4F1	POU4F2	PPARD	PPP1R13B	PPP1R15A	PRKCA	PRKCD	PRKDC	PRODH	PTGIS	PTH	PYCARD	QRICH1	RHOT1	RHOT2	RIPK1	RIPK3	RNF186	RNF41	RPS27L	RRP8	RTL10	SCN2A	SELENOK	SFN	SGPL1	SHH	SIRT1	SIVA1	SLFN12	SMAD3	SMAD4	SNW1	SOD2	SORT1	SPI1	SST	SSTR3	ST20	STK11	STK24	STK25	SYK	TFPT	TGFB1	TGFB2	TIMM50	TLR3	TM2D1	TMEM109	TMEM117	TMEM238L	TNF	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF1A	TNFRSF1B	TNFRSF25	TNFSF10	TNFSF12	TOPORS	TP53	TP53BP2	TP63	TP73	TRADD	TRAF2	TRAF5	TRIB3	UACA	UBE4B	URI1	USP28	VDAC2	XBP1	ZDHHC3	ZNF385B	ZNF622
KE2036_Activation_of_metabotropic_glutamate_receptor_GO:0007216	G protein-coupled glutamate receptor signaling pathway	FYN	GNAQ	GRIK3	GRM1	GRM2	GRM3	GRM4	GRM5	GRM6	GRM7	GRM8	HOMER1	HOMER2	HOMER3	TRPM1
KE2037_Inositol_triphosphate_receptor_activation_GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	CCL3	CCR5	FASLG	ITPR1	NOL3	RYR1	RYR2	RYR3	TMEM38A	TMEM38B	TRDN
KE2038_Activation_of_calpain_signalling_GO:0006508	proteolysis	ACAN	ACE	ACE2	ACR	ACTMAP	ADAM10	ADAM11	ADAM12	ADAM15	ADAM17	ADAM18	ADAM19	ADAM2	ADAM20	ADAM21	ADAM22	ADAM23	ADAM28	ADAM29	ADAM30	ADAM32	ADAM33	ADAM7	ADAM8	ADAM9	ADAMDEC1	ADAMTS1	ADAMTS10	ADAMTS12	ADAMTS13	ADAMTS14	ADAMTS15	ADAMTS16	ADAMTS17	ADAMTS18	ADAMTS19	ADAMTS2	ADAMTS20	ADAMTS3	ADAMTS4	ADAMTS5	ADAMTS6	ADAMTS7	ADAMTS8	ADAMTS9	ADGB	ADGRV1	AEBP1	AFG3L2	AGA	AGBL1	AGBL2	AGBL3	AGBL4	AGBL5	AGTPBP1	ALG13	AMZ1	AMZ2	ANPEP	AOPEP	APEH	APH1A	APH1B	APOH	ASPRV1	ASRGL1	ASTL	ATG4A	ATG4B	ATG4C	ATG4D	ATP23	ATP6AP2	ATXN3	ATXN3L	AZU1	BACE1	BACE2	BAP1	BCHE	BLMH	BMP1	BRCC3	C1R	C1RL	C1S	C2	CAPN1	CAPN10	CAPN11	CAPN12	CAPN13	CAPN14	CAPN15	CAPN2	CAPN3	CAPN5	CAPN7	CAPN8	CAPN9	CAPNS1	CARD16	CARD17P	CARD18	CARD8	CASP1	CASP10	CASP12	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP9	CELA1	CELA2A	CELA2B	CELA3A	CELA3B	CFB	CFD	CFH	CFI	CFLAR	CIROP	CLCA1	CLCA2	CLCA4	CLN3	CLPP	CLPX	CMA1	CNDP1	CNDP2	COLEC10	COLEC11	COPS5	CORIN	CPA1	CPA2	CPA3	CPA4	CPA5	CPA6	CPB1	CPB2	CPD	CPE	CPM	CPN1	CPNE1	CPO	CPQ	CPVL	CPXM1	CPXM2	CPZ	CSTL1	CTRB1	CTRB2	CTRC	CTRL	CTSA	CTSB	CTSC	CTSD	CTSE	CTSF	CTSG	CTSH	CTSK	CTSL	CTSO	CTSS	CTSV	CTSW	CTSZ	CUL7	CUZD1	CYLD	DAG1	DCD	DDI1	DDI2	DESI1	DESI2	DHH	DNPEP	DPEP1	DPEP2	DPEP3	DPP10	DPP3	DPP4	DPP6	DPP7	DPP8	DPP9	ECE1	ECE2	ECEL1	EEF1AKMT4-ECE2	EIF3F	ELANE	ENDOU	ENPEP	ERAP1	ERAP2	ERMP1	ERO1B	ERVK-9	ESPL1	F10	F11	F12	F2	F3	F7	F9	FAM111A	FAM111B	FAP	FBXL2	FBXL6	FBXO2	FBXO3	FBXO6	FBXW2	FCN1	FCN2	FCN3	FGA	FGB	FGG	FOLH1	FOLH1B	FURIN	FXN	GGT1	GGT3P	GGT5	GZMA	GZMB	GZMH	GZMK	GZMM	HABP2	HERV-K104	HERVK_113	HGFAC	HINT1	HJV	HM13	HMCES	HP	HPN	HPR	HTRA1	HTRA2	HTRA3	HTRA4	IDE	IHH	IMMP1L	IMMP2L	JMJD7	JOSD1	JOSD2	KDM8	KEL	KLK1	KLK10	KLK11	KLK12	KLK13	KLK14	KLK15	KLK2	KLK3	KLK4	KLK5	KLK6	KLK7	KLK8	KLK9	KLKB1	KY	LACTB	LAP3	LCN1	LGMN	LMLN	LNPEP	LONP1	LONP2	LPA	LRP8	LTA4H	LTF	LVRN	MAFB	MALT1	MASP1	MASP2	MATCAP1	MATCAP2	MBL2	MBOAT4	MBTPS1	MBTPS2	MEP1A	MEP1B	METAP1	METAP1D	METAP2	MINDY1	MINDY2	MINDY3	MINDY4	MIPEP	MME	MMEL1	MMP1	MMP10	MMP11	MMP12	MMP13	MMP14	MMP15	MMP16	MMP17	MMP19	MMP2	MMP20	MMP21	MMP23B	MMP24	MMP25	MMP26	MMP27	MMP28	MMP3	MMP7	MMP8	MMP9	MPND	MST1	MST1L	MYH9	MYRF	MYRFL	MYSM1	NAALAD2	NAALADL1	NAPSA	NCSTN	NEDD8	NLN	NLRP1	NPEPL1	NPEPPS	NPEPPSL1	NRDC	NRIP2	NRIP3	NUP98	OGT	OLR1	OMA1	OTUB1	OTUB2	OTUD1	OTUD3	OTUD4	OTUD5	OTUD6A	OTUD6B	OTUD7A	OTUD7B	OTULIN	OVCH1	OVCH2	P4HB	PAPPA	PAPPA2	PARK7	PARL	PARP1	PCOLCE	PCSK1	PCSK2	PCSK4	PCSK5	PCSK6	PCSK7	PCSK9	PEPD	PGA3	PGA4	PGA5	PGC	PGK1	PGPEP1	PGPEP1L	PHEX	PIDD1	PIGK	PIK3C3	PIP	PISD	PITRM1	PLA2G7	PLAT	PLAU	PLAUR	PLBD1	PLG	PM20D1	PM20D2	PMPCA	PMPCB	PRCP	PREP	PREPL	PRKCQ	PROC	PROZ	PRRG1	PRRG2	PRRG3	PRRG4	PRSS1	PRSS12	PRSS16	PRSS2	PRSS21	PRSS22	PRSS23	PRSS27	PRSS29P	PRSS3	PRSS33	PRSS36	PRSS37	PRSS38	PRSS3P2	PRSS41	PRSS42P	PRSS45P	PRSS46P	PRSS47P	PRSS48	PRSS50	PRSS51	PRSS53	PRSS54	PRSS55	PRSS56	PRSS57	PRSS58	PRSS8	PRTN3	PSEN1	PSEN2	PSENEN	PSMB10	PSMB11	PSMB5	PSMB6	PSMB7	PSMB8	PSMB9	PSMC4	PSMD14	PSMD8	PTCH1	RBMX	RBP3	RCE1	RELN	REN	RET	RHBDD1	RHBDL1	RHBDL2	RHBDL3	RNPEP	RNPEPL1	SCG5	SCPEP1	SCRN1	SCRN2	SCRN3	SDE2	SEC11A	SEC11B	SEC11C	SENP1	SENP2	SENP3	SENP5	SENP6	SENP7	SENP8	SHH	SLC30A5	SLC30A8	SPCS1	SPCS3	SPG7	SPPL2A	SPPL2B	SPPL2C	SPPL3	SPRTN	SRGN	ST14	STAMBP	STAMBPL1	STOML2	SVBP	TASP1	TBL1X	TGFB1	TGM2	THBD	THOP1	TINAG	TLL1	TLL2	TM2D3	TMEM208	TMPRSS11A	TMPRSS11B	TMPRSS11D	TMPRSS11E	TMPRSS11F	TMPRSS12	TMPRSS13	TMPRSS15	TMPRSS2	TMPRSS3	TMPRSS4	TMPRSS5	TMPRSS6	TMPRSS7	TMPRSS9	TNFAIP3	TPP1	TPP2	TPSAB1	TPSB2	TPSD1	TPSG1	TRABD2A	TRABD2B	TRHDE	TYSND1	UBA3	UBD	UBE3A	UCHL1	UCHL3	UCHL5	UFSP1	UFSP2	UQCRC2	USP1	USP10	USP11	USP12	USP13	USP14	USP15	USP16	USP17L1	USP17L10	USP17L11	USP17L12	USP17L13	USP17L15	USP17L17	USP17L18	USP17L19	USP17L2	USP17L20	USP17L21	USP17L22	USP17L24	USP17L3	USP17L4	USP17L5	USP17L6P	USP17L7	USP17L8	USP18	USP19	USP2	USP20	USP21	USP22	USP24	USP25	USP26	USP27X	USP28	USP29	USP3	USP30	USP31	USP32	USP33	USP34	USP35	USP36	USP37	USP38	USP4	USP40	USP42	USP43	USP44	USP45	USP46	USP47	USP48	USP49	USP5	USP51	USP54	USP6	USP7	USP8	USP9X	USP9Y	USPL1	VASH1	VASH2	VCPIP1	VHL	VSIR	WFDC2	XPNPEP1	XPNPEP2	XPNPEP3	YIPF5	YME1L1	YOD1	ZMPSTE24	ZRANB1
KE2039_Inhibition_GABAA_receptor_GO:0007214	gamma-aminobutyric acid signaling pathway	ATF4	GABBR1	GABBR2	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB1	GABRB2	GABRB3	GABRD	GABRE	GABRG1	GABRG2	GABRG3	GABRQ	GABRR1	GABRR3	GNAI2	GPR156	PLCL1	PLCL2	SHISA7	SLC12A2
KE2085_Pulmonary_epithelial_injury_GO:0009611	response to wounding	ACTB	ACTG1	ACVRL1	ADAM17	ADAMTS13	ADIPOR2	ADORA2A	ADORA3	ADRA2A	ADRA2B	ADRA2C	AGER	AK3	ALOX15	ANGPT1	ANGPT2	ANGPT4	ANGPTL1	ANGPTL2	ANGPTL4	ANGPTL6	ANGPTL7	ANO5	ANO6	ANXA5	ANXA8	APOA4	APOD	APOH	ARF4	ARHGAP24	ARHGAP35	ARHGEF19	ARL8B	AURKA	AXL	BLOC1S3	BNIP3	C4BPB	C6orf89	CARMIL2	CCN2	CCR1	CCR2	CD151	CD34	CD36	CD40	CD40LG	CD44	CD59	CD9	CDK1	CDKN1A	CEACAM1	CERS2	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4BP1	CHMP4C	CHMP5	CHMP6	CHMP7	CLDN1	CLIC1	COL3A1	COL5A1	CORO1B	CPB2	CSPG5	CSRP1	CTNNA1	CTSG	CX3CR1	CYP4F11	CYP4F2	DAG1	DCBLD2	DDIT3	DDR1	DGKA	DGKB	DGKD	DGKE	DGKG	DGKH	DGKI	DGKK	DGKQ	DGKZ	DHFR	DPYSL3	DRD2	DSP	DST	EDNRA	ENPP4	ENTPD1	EPB41L4B	EPO	EPPK1	ERBB2	ERBB3	EREG	EVPL	F10	F11	F12	F13A1	F13B	F2	F2R	F2RL1	F2RL2	F2RL3	F3	F5	F7	F8	F9	FBLN1	FER1L5	FERMT3	FGA	FGB	FGF1	FGF10	FGF2	FGF7	FGFR1OP2	FGG	FGL1	FIBP	FLNA	FLRT3	FN1	FOLR1	FZD7	GAP43	GATA1	GATA2	GATA4	GGCX	GIPR	GNA12	GNAQ	GNAS	GP1BA	GP1BB	GP5	GP6	GP9	HBB	HBEGF	HGFAC	HIF1A	HMOX1	HNF4A	HOXB13	HPSE	HRG	HSPB1	IGF1	IL17A	IL6	ILK	INHBB	INS	ISL1	ITGA2	ITGA5	ITGAV	ITGB1	ITGB3	ITGB4	ITGB5	ITPK1	ITPR3	JAK2	JAML	JMJD1C	KCNB1	KCNK2	KDR	KLK6	KLK8	KLKB1	KNG1	KRT6A	LACRT	LCK	LMAN1	LRG1	LYN	LYVE1	MACF1	MAP1B	MAP2K1	MAPK14	MAPK8IP3	MAPK9	MCAM	MDK	METAP1	MIA3	MMP12	MMP2	MMRN1	MORN4	MPIG6B	MRTFA	MTR	MYH9	MYL12A	MYL9	MYOF	MYOZ1	NDNF	NF1	NFKBIZ	NOG	NOTCH2	NPPC	NPR2	NREP	NRG1	NRP1	NTRK1	NTRK3	ODAM	P2RX4	P2RY1	P2RY12	PABPC4	PAFAH2	PAK1	PAX6	PDCD10	PDGFA	PDGFB	PDGFRA	PDPN	PEAR1	PF4	PIK3CA	PIK3CB	PIK3CG	PLAT	PLAU	PLAUR	PLCG2	PLEC	PLEK	PLET1	PLG	PLSCR1	POFUT3	POU5F1	PPIA	PPL	PPP3CA	PRCP	PROC	PROCR	PROS1	PROZ	PRRG1	PRRG2	PRRG3	PRRG4	PRSS56	PTPRJ	RAB3A	RAC1	RAF1	RAP2B	RASA3	REG3A	RHOA	RHOC	RIPOR1	RTN4RL1	RTN4RL2	SAA1	SARM1	SCARB1	SCUBE1	SERPINA1	SERPINA10	SERPINC1	SERPIND1	SERPING1	SFTA3	SLC11A1	SLC6A4	SMAD3	SMPD1	SOD1	SOX2	SPRR3	SRC	SRF	STXBP1	STXBP3	SYK	SYT11	SYT7	SYTL4	TFPI	TFPI2	TGFB1	TGFB2	TGFBR1	THBD	THBS1	TLN1	TLR3	TLR4	TMEFF2	TMIGD3	TNC	TNF	TOR1A	TPM1	TREM2	TREML1	TRIM72	TSKU	TSPO	TUBB1	TYRO3	TYROBP	UBASH3B	UCK2	VASH1	VAV1	VAV2	VAV3	VCL	VEGFA	VKORC1	VPS4A	VPS4B	VWF	WAS	WNT1	WNT5A	WNT7A	YAP1	ZFP36	ZFP36L1	ZFP36L2
KE2086_Airway_inflammation_GO:0006954	inflammatory response	ABCF1	ABHD8	ACER3	ACKR1	ACKR2	ACOD1	ACVR1	ADAM17	ADAM8	ADCY1	ADCY8	ADGRE2	ADGRE5	ADM	ADORA1	ADORA2A	ADORA3	AFAP1L2	AGER	AGR2	AGTR1	AGTR2	AHSG	AIF1	AIM2	AIMP1	ALOX15	ALOX5	ANO6	ANXA1	AOC3	APCS	APIP	APOL2	APOL3	APP	ASS1	ATRN	AZU1	BCL6	BDKRB1	BDKRB2	BIRC2	BIRC3	BLNK	BMP2	BMP6	BMPR1B	BTK	C15orf39	C1QA	C2CD4A	C2CD4B	C3	C3AR1	C4A	C4B	C5	C5AR1	C5AR2	CAMK1D	CAMK4	CAMP	CARD18	CARD8	CASP1	CASP3	CASP4	CASP6	CASP8	CCL1	CCL11	CCL13	CCL14	CCL15	CCL16	CCL17	CCL18	CCL19	CCL2	CCL20	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL3L1	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCRL2	CD14	CD163	CD180	CD36	CD40	CD40LG	CD44	CD47	CD5L	CD6	CD68	CDO1	CEBPB	CELA1	CERS6	CFH	CHI3L1	CHIA	CHST1	CHST2	CHST4	CHUK	CLEC7A	CLU	CMKLR1	CNR2	CNTF	CRH	CRHBP	CRP	CSF1	CSF1R	CTNNBIP1	CUL3	CX3CL1	CX3CR1	CXCL1	CXCL10	CXCL11	CXCL13	CXCL2	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR2	CXCR3	CXCR4	CXCR6	CYBA	CYBB	DAB2IP	DHX9	DPEP1	DPP9	ELANE	ELF3	EPO	F11R	F12	F2	F2R	F2RL1	F3	F8	FADS2	FCER1A	FCER1G	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FFAR2	FFAR3	FFAR4	FN1	FOLR2	FOS	FPR1	FPR2	FPR3	FUT4	FUT7	GATA3	GBP5	GGT5	GPER1	GPR32	GPR32P1	GPR33	GPR68	GRN	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GZMA	GZMB	GZMK	HAVCR2	HBA1	HBB	HCK	HDAC4	HDAC5	HDAC9	HIF1A	HK1	HLA-DRB1	HMGB1	HMGB2	HMOX1	HNRNPA0	HP	HRH1	HRH4	HSPG2	HYAL1	HYAL3	IFI16	IFI27	IFNA2	IFNG	IFNGR1	IFNGR2	IGHE	IGHG1	IKBKB	IKBKG	IL10RB	IL13	IL17A	IL17B	IL17C	IL17D	IL17F	IL17RA	IL17RC	IL17RE	IL18	IL18R1	IL18RAP	IL1A	IL1B	IL1F10	IL1R1	IL1RAP	IL1RL1	IL1RL2	IL1RN	IL20RA	IL22	IL22RA1	IL23A	IL23R	IL25	IL26	IL27	IL2RA	IL33	IL34	IL36A	IL36B	IL36G	IL36RN	IL37	IL4	IL4R	IL5	IL6	IL6R	IL9	INS	IRAK1	IRAK2	IRAK4	IRF5	IRGM	ITCH	ITGAL	ITGAM	ITGB1	ITGB2	ITIH4	JAK2	KDM4D	KDM6B	KIT	KLKB1	KLRG1	KNG1	KRT16	LACC1	LAT	LBP	LCN2	LGALS9	LIAS	LOXL3	LRP1	LTB4R	LXN	LY75	LY86	LY96	LYN	LYZ	MACIR	MAP3K20	MAP3K7	MAPK9	MAPKAPK2	MAPT	MBL2	MDK	MEFV	MEP1B	MFHAS1	MGLL	MIF	MMP25	MRGPRX1	MSMP	MTOR	MYD88	NAIP	NAMPT	NCR3	NDST1	NFAM1	NFATC3	NFATC4	NFKB1	NFKBID	NFKBIZ	NFX1	NINJ1	NKG7	NLRC4	NLRP1	NLRP10	NLRP2	NLRP3	NLRP4	NLRP6	NLRP9	NOD1	NOS2	NOX1	NOX4	NPFF	NR1H4	NR3C1	NR4A1	NRROS	ODAM	OLR1	ORM1	ORM2	PARK7	PARP4	PF4	PF4V1	PIK3CD	PIK3CG	PJA2	PLA2G2A	PLA2G2D	PLA2G2E	PLA2G4B	PLA2G4C	PLD3	PLD4	PLGRKT	PLSCR1	PNMA1	PPBP	PRDX5	PRKCQ	PRKCZ	PRKD1	PRMT2	PROK2	PSEN1	PSTPIP1	PTAFR	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR	PTN	PTX3	PXK	PYCARD	PYDC2	PYDC5	RAC1	RARRES2	REG3A	REG3G	REL	RELA	RELB	RIPK1	RIPK2	RPS6KA4	RPS6KA5	S100A12	S100A8	S100A9	S1PR3	SAA1	SAA2	SAA4	SBNO1	SCG2	SCN11A	SCUBE1	SELE	SEMA7A	SERPINA1	SERPINA3	SERPINF2	SETD4	SIGIRR	SIGLEC1	SLAMF8	SLC11A1	SLC18A2	SMAD1	SMPDL3B	SNAP23	SNCA	SPINK7	STAB1	STAT3	STK39	SYK	TAB2	TAC1	TAC4	TACR1	TBK1	TBX21	TBXA2R	TFRC	TGFB1	THBS1	THEMIS2	TICAM1	TICAM2	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TMIGD3	TNF	TNFAIP3	TNFAIP6	TNFRSF1A	TNFRSF1B	TNFRSF4	TNFSF4	TNIP1	TNIP2	TNIP3	TOLLIP	TRADD	TRAF2	TRAF3IP2	TRAF5	TREM2	TRIL	TRIM14	TRIM21	TRIM31	TSPAN18	TUSC2	TXNIP	TYROBP	USP14	VCAM1	VNN1	VPS54	WNK4	WNT5A	XCL1	XCL2	XCR1	ZBP1	ZC3H12A	ZEB2	ZNF580
KE2088_Dysfunction_of_respiratory_system_GO:0003016	respiratory system process	ECEL1	GAA	NEK10	ODAD4	TNNC1	YWHAZ
KE2093_Brain_thyroid_hormone_T4_T3_decreased_GO:0042403	thyroid hormone metabolic process	CPQ	CRYM	CTSB	CTSK	DIO1	DIO2	DIO3	DUOX1	DUOX2	FOXE1	IYD	SLC16A2	SLC26A7	SLC5A5	SULT1A1	SULT1A3	SULT1A4	SULT1B1	SULT2A1	TG	TPO
KE2093_Brain_thyroid_hormone_T4_T3_decreased_GO:0070327	thyroid hormone transport	CRYM	SERPINA7	SLC16A10	SLC16A2	SLC17A4	SLC3A2	SLC7A5	SLC7A8	SLCO1B1	SLCO1C1	SLCO4A1	TUBB1
KE2094_Abnormal_neuroblast_migration_GO:0097402	neuroblast migration	SIX3
KE2107_Hypomyelination_GO:0042552	myelination	ABCA2	ABCD1	ABCD2	ACER3	ACSBG1	ADGRG6	AMIGO1	ANK2	ARHGEF10	B4GALT5	B4GALT6	BCAS1	CD9	CFH	CLDN5	CLU	CMTM8	CNTN1	CNTNAP1	CXCR4	DAG1	DEGS1	DHH	DICER1	EIF2B2	EIF2B4	EIF2B5	EPB41L3	ERBB3	GAL3ST1	GPC1	GPM6B	GRB2	HES5	HRAS	HYCC1	KLK6	LGI4	LPAR1	MAG	MAL	MAL2	MALL	MAP2K1	MAP2K2	MAPK1	MAPK3	MARVELD1	MBP	MIOS	MPZ	MYOC	MYRF	NCMAP	NDRG1	NF1	NFASC	OLIG2	PALS1	PARD3	PLEC	PLLP	PLP1	PMP22	PRX	PTEN	RAF1	SBF2	SCN2A	SCN8A	SELENOI	SIRT2	SKI	SLC8A3	SOD1	SOS1	SOX10	TENM4	TGFB1	TMEM163	TNFRSF21	TPPP	UGT8	ZNF24
KE2108_Altered_white_brain_matter_GO:0042552	myelination	ABCA2	ABCD1	ABCD2	ACER3	ACSBG1	ADGRG6	AMIGO1	ANK2	ARHGEF10	B4GALT5	B4GALT6	BCAS1	CD9	CFH	CLDN5	CLU	CMTM8	CNTN1	CNTNAP1	CXCR4	DAG1	DEGS1	DHH	DICER1	EIF2B2	EIF2B4	EIF2B5	EPB41L3	ERBB3	GAL3ST1	GPC1	GPM6B	GRB2	HES5	HRAS	HYCC1	KLK6	LGI4	LPAR1	MAG	MAL	MAL2	MALL	MAP2K1	MAP2K2	MAPK1	MAPK3	MARVELD1	MBP	MIOS	MPZ	MYOC	MYRF	NCMAP	NDRG1	NF1	NFASC	OLIG2	PALS1	PARD3	PLEC	PLLP	PLP1	PMP22	PRX	PTEN	RAF1	SBF2	SCN2A	SCN8A	SELENOI	SIRT2	SKI	SLC8A3	SOD1	SOS1	SOX10	TENM4	TGFB1	TMEM163	TNFRSF21	TPPP	UGT8	ZNF24
KE2109_Binding_extracellular_matrix_protein_laminin_GO:0007160	cell-matrix adhesion	ACTN1	ACTN2	ACTN3	ADAM15	ADAM9	ADAMTS12	ADAMTS13	ADAMTS9	ANGPTL3	ARHGEF7	BCAM	BCR	CCL21	CD34	CD44	CD63	CD96	CDH11	COL13A1	COL17A1	COL3A1	CORO2B	CTTN	DAG1	DDR1	DEFB118	DLC1	ECM2	EMILIN1	EMP2	EPDR1	FBLN5	FERMT1	FERMT2	FERMT3	FGA	FGB	FGG	FN1	FRAS1	FREM1	FREM2	FREM3	HOXD3	HPSE	ILK	ITGA1	ITGA10	ITGA11	ITGA2	ITGA2B	ITGA3	ITGA4	ITGA5	ITGA6	ITGA7	ITGA8	ITGA9	ITGAE	ITGAL	ITGAM	ITGAV	ITGAX	ITGB1	ITGB1BP1	ITGB2	ITGB3	ITGB4	ITGB5	ITGB6	ITGB7	ITGB8	ITGBL1	L1CAM	LIMS1	LYVE1	MADCAM1	MKLN1	MSLN	MSLNL	MUC4	NID1	NID2	NPNT	OTOA	PARVG	PEAK1	PIP5K1A	PKD1	PPFIA1	PPFIA2	PTPRK	RAC1	RCC2	RHOD	RSU1	SGCE	SIGLEC1	SNED1	SORBS1	SRC	STRC	STRCP1	SVEP1	TAOK2	TECTA	TESK2	THBS3	THSD1	THY1	TIAM1	TIMM10B	TMEM8B	TNN	TRIP6	TSC1	TSPAN11	VCAM1	VCL	VTN	VWA2	WHAMM	ZYX
KE2110_Disrupted_binding_laminin_beta1_integrin_receptors_with_laminin_GO:0007160	cell-matrix adhesion	ACTN1	ACTN2	ACTN3	ADAM15	ADAM9	ADAMTS12	ADAMTS13	ADAMTS9	ANGPTL3	ARHGEF7	BCAM	BCR	CCL21	CD34	CD44	CD63	CD96	CDH11	COL13A1	COL17A1	COL3A1	CORO2B	CTTN	DAG1	DDR1	DEFB118	DLC1	ECM2	EMILIN1	EMP2	EPDR1	FBLN5	FERMT1	FERMT2	FERMT3	FGA	FGB	FGG	FN1	FRAS1	FREM1	FREM2	FREM3	HOXD3	HPSE	ILK	ITGA1	ITGA10	ITGA11	ITGA2	ITGA2B	ITGA3	ITGA4	ITGA5	ITGA6	ITGA7	ITGA8	ITGA9	ITGAE	ITGAL	ITGAM	ITGAV	ITGAX	ITGB1	ITGB1BP1	ITGB2	ITGB3	ITGB4	ITGB5	ITGB6	ITGB7	ITGB8	ITGBL1	L1CAM	LIMS1	LYVE1	MADCAM1	MKLN1	MSLN	MSLNL	MUC4	NID1	NID2	NPNT	OTOA	PARVG	PEAK1	PIP5K1A	PKD1	PPFIA1	PPFIA2	PTPRK	RAC1	RCC2	RHOD	RSU1	SGCE	SIGLEC1	SNED1	SORBS1	SRC	STRC	STRCP1	SVEP1	TAOK2	TECTA	TESK2	THBS3	THSD1	THY1	TIAM1	TIMM10B	TMEM8B	TNN	TRIP6	TSC1	TSPAN11	VCAM1	VCL	VTN	VWA2	WHAMM	ZYX
KE2111_Decreased_neural_progenitor_cell_adhesion_to_laminin_GO:0007160	cell-matrix adhesion	ACTN1	ACTN2	ACTN3	ADAM15	ADAM9	ADAMTS12	ADAMTS13	ADAMTS9	ANGPTL3	ARHGEF7	BCAM	BCR	CCL21	CD34	CD44	CD63	CD96	CDH11	COL13A1	COL17A1	COL3A1	CORO2B	CTTN	DAG1	DDR1	DEFB118	DLC1	ECM2	EMILIN1	EMP2	EPDR1	FBLN5	FERMT1	FERMT2	FERMT3	FGA	FGB	FGG	FN1	FRAS1	FREM1	FREM2	FREM3	HOXD3	HPSE	ILK	ITGA1	ITGA10	ITGA11	ITGA2	ITGA2B	ITGA3	ITGA4	ITGA5	ITGA6	ITGA7	ITGA8	ITGA9	ITGAE	ITGAL	ITGAM	ITGAV	ITGAX	ITGB1	ITGB1BP1	ITGB2	ITGB3	ITGB4	ITGB5	ITGB6	ITGB7	ITGB8	ITGBL1	L1CAM	LIMS1	LYVE1	MADCAM1	MKLN1	MSLN	MSLNL	MUC4	NID1	NID2	NPNT	OTOA	PARVG	PEAK1	PIP5K1A	PKD1	PPFIA1	PPFIA2	PTPRK	RAC1	RCC2	RHOD	RSU1	SGCE	SIGLEC1	SNED1	SORBS1	SRC	STRC	STRCP1	SVEP1	TAOK2	TECTA	TESK2	THBS3	THSD1	THY1	TIAM1	TIMM10B	TMEM8B	TNN	TRIP6	TSC1	TSPAN11	VCAM1	VCL	VTN	VWA2	WHAMM	ZYX
KE2112_Disturbed_radial_glia_cell_alignment_and_migration_GO:0008347	glial cell migration	ADGRG1	AZU1	CCL2	CCL3	CD9	COL3A1	DAB1	DAB2IP	DISC1	EPHA4	HEXB	LAMB1	MBOAT7	MMP14	P2RY1	P2RY12	PAFAH1B1	RELN	RTN4	SOCS7	SRGAP2	SRGAP2C	SUN1	SUN2	SYNE2	TGFB2	TSPO	ZMIZ1
KE2113_Decreased_radial_glia_cell_density_GO:0014009	glial cell proliferation	AREG	CLU	CSF1	CSF1R	CX3CL1	EEF2	IL33	IL34	NF2	PENK	SOX11	SOX4	TREM2
KE2113_Decreased_radial_glia_cell_density_GO:0010001	glial cell differentiation	ABCA2	ADGRG6	ADORA2A	AGER	ANO1	APP	ARHGEF10	B4GALT5	B4GALT6	BNIP3	BOK	C1QA	C5AR1	CD9	CDH2	CDK5	CDK6	CDKN2C	CERS5	CFH	CLU	CNTF	CNTN1	CNTNAP1	CSK	CSPG5	CUL4B	DAG1	DICER1	DLL1	EGR2	EIF2B1	EIF2B2	EIF2B3	EIF2B4	EIF2B5	EOMES	ERBB2	ERBB3	FGF10	FPR2	GPC1	GPM6B	GPR157	GPR17	GRB2	GRN	GSTP1	HES1	HES5	HRAS	IFNG	IFNGR1	LGI4	LPAR1	LRP1	LYN	MAG	MAP2K1	MAP2K2	MAPK1	MAPK3	MAPT	MDK	METRN	METTL14	METTL3	MIOS	MMP24	MXRA8	MYOC	MYRF	NCMAP	NDRG1	NF1	NFIB	NOTCH1	NR3C1	NRROS	NSUN5	NTRK2	OLIG1	OLIG2	PALS1	PARD3	PAX2	PHOX2B	PICK1	PLEC	PLP1	PRDM8	PRX	PSEN1	PTEN	PTPRZ1	QKI	RAF1	RELN	S100A9	S100B	SHH	SIRT2	SKI	SLC8A3	SOD1	SOS1	SOX10	SOX11	SOX13	SOX2	SOX4	SOX6	SOX8	SOX9	STAT3	TENM4	TGFB1	TLR2	TNF	TPPP	TREM2	TUBA1A	VPS54	VTN	ZEB2	ZNF488
KE2114_Disturbed_cortical_architecture_GO:0021987	cerebral cortex development	ADGRG1	AKIRIN2	ARHGAP11B	ATIC	BBS2	BBS4	BNIP3	BTBD3	CCDC85C	CDK5R1	CNTNAP2	COL3A1	CSNK2A2	DAB1	DAB2IP	DISC1	DIXDC1	EFHC1	EOMES	FAT4	FGF13	FLNA	FOS	FOXP2	GART	GRIA1	GSK3B	HTR6	KCNA2	KDM1A	KIF14	KIF26A	LAMB1	LHX6	MBOAT7	MCPH1	MDK	MGARP	MKKS	NARS1	NCAPG2	NCAPH2	NCOA1	NDE1	NDEL1	NEFL	NF1	NOTCH2NLA	NOTCH2NLB	NOTCH2NLC	NPY	NSUN5	NTRK2	P2RY12	PAFAH1B1	PALS1	PAX6	PEX13	PHACTR1	PLCB1	PPP1R9B	RELN	ROBO1	RTN4	SLC2A1	SLC38A2	SLIT2	SMC2	SMC4	SOCS7	SRD5A1	SRGAP2	SRGAP2C	SUN1	SUN2	SYNE2	TACC1	TACC2	TACC3	TBR1	TMEM14B	TRAPPC9	TUBA1A	TUBB2A	TUBB2B	WDR62	XAB2	ZMIZ1
KE2115_Altered_cholesterol_metabolism_GO:0008203	cholesterol metabolic process	ABCA1	ABCA5	ABCG1	ACAA2	ACLY	AKR1D1	ANGPTL3	APOA1	APOA4	APOA5	APOB	APOBR	APOE	APOF	APOL1	APOL2	ARV1	CES1	CETP	CH25H	CLN6	CLN8	CUBN	CYB5R3	CYP11A1	CYP11B1	CYP11B2	CYP1A2	CYP27A1	CYP2C9	CYP2D6	CYP39A1	CYP3A4	CYP46A1	CYP51A1	CYP7A1	CYP7B1	DHCR24	DHCR7	DISP3	EBP	ERLIN1	ERLIN2	FDFT1	FDPS	FDX1	FDXR	G6PD	GBA1	GBA2	HDLBP	HMGCR	HMGCS1	HMGCS2	HSD17B7	IDI1	IDI2	IL4	INSIG1	INSIG2	LBR	LCAT	LDLR	LDLRAP1	LIMA1	LIPE	LSS	MBTPS1	MBTPS2	MSMO1	MVD	MVK	NFE2L1	NPC1	NPC1L1	NPC2	NR0B2	NSDHL	OSBPL1A	OSBPL5	PCSK9	PIP4P1	PLPP6	PMVK	PPARD	PRKAA1	PRKAA2	SC5D	SCAP	SCARF1	SNX17	SOAT1	SOAT2	SQLE	SREBF1	SREBF2	STAR	STARD3	SULT2A1	SULT2B1	TM7SF2	TSKU	VLDLR
KE2116_Decreased_oligodendrocyte_differentiation_GO:0048709	oligodendrocyte differentiation	ABCA2	B4GALT5	B4GALT6	BNIP3	BOK	CD9	CDK5	CDKN2C	CERS5	CFH	CLU	CNTN1	CNTNAP1	CSK	EIF2B1	EIF2B2	EIF2B3	EIF2B4	EIF2B5	GPM6B	GPR17	GSTP1	HES5	LPAR1	LYN	MAG	MIOS	MYRF	NOTCH1	NSUN5	NTRK2	OLIG1	OLIG2	PLP1	PRDM8	PTEN	PTPRZ1	SHH	SLC8A3	SOX10	SOX11	SOX13	SOX6	SOX8	SOX9	TENM4	TGFB1	TPPP	VTN	ZNF488
KE2148_Increased_LCN2_iron_complex_binds_to_SLC22A17_receptor_in_neuron_GO:0006898	receptor-mediated endocytosis	ACE2	ACKR3	ADM	ADRB2	AMN	AP1S1	AP2A1	AP2A2	AP2B1	AP2M1	AP2S1	AP3M1	APOE	ARHGAP27	ARHGEF37	ARR3	ARRB1	ARRB2	ASGR1	CALCRL	CALY	CANX	CAV1	CAV2	CAV3	CCDC158	CD14	CD36	CD81	CD9	CEACAM1	CLEC4M	CLEC9A	CLN3	CLTA	CLTB	CLTC	CLTCL1	CTSL	CTTN	CUBN	CXCL16	CXCL8	CXCR1	CXCR2	DAB2	DLL1	DNAJC13	DNAJC6	DNM1	DNM2	DPP4	DRD2	DRD3	ENTREP1	EPS15	FCER1G	FCER2	FCGR2B	FCHO1	FCHO2	FCHSD2	FCMR	FNBP1L	FOLR1	FPR2	GAK	GAS7	GPR107	GRB2	GRIA1	GRK2	GRK3	GRK4	GTF2H2	HFE	HGS	HIP1R	HMMR	HSPA8	HSPG2	IGF2R	INPP5F	INSR	ITCH	ITGA4	ITGAM	ITGB1	ITGB2	ITSN1	ITSN2	LDLR	LDLRAD3	LDLRAP1	LILRB1	LILRB4	LMBR1L	LMBRD1	LRP1	LRP1B	LRP2	LRP3	LY75	LYVE1	M6PR	MAGI2	MARCO	MICALL1	MRC1	MRC2	MSR1	NEDD4	NEDD4L	NLGN3	PDLIM7	PI4KB	PICALM	PIKFYVE	PIP5K1C	PLA2R1	PLXNB2	PPT1	RAB15	RAB31	RAB5A	RAB9A	RAB9B	RABEPK	RALA	RALB	RALBP1	RAMP1	RAMP2	RAMP3	RNASEK	SAG	SCARB2	SCARF1	SCYL2	SDC1	SFTPD	SGIP1	SIGLEC1	SLC9B2	SNAP91	SNCA	SNX1	SNX9	SORL1	STAB1	STAB2	STON1	STON2	SYK	SYNJ1	SYNJ2	TFR2	TFRC	TMEM108	TPCN2	VLDLR	WASF1
KE2149_Increased_intracelluar_Iron_accumulation_GO:0006879	intracellular iron ion homeostasis	ABCB6	ABCB7	ACO1	ACVR2B	ALAS2	ATP13A2	ATP6AP1	ATP6V0A2	ATP6V0D1	ATP6V1A	ATP6V1G1	B2M	BMP2	BMP6	BOLA1	BOLA2	BOLA3	CISD1	CP	CUL1	CYB561	CYB561A3	CYBRD1	EGLN1	ERFE	FBXL5	FLVCR1	FRRS1	FTH1	FTH1P19	FTHL17	FTL	FTMT	FXN	GDF2	GLRX3	GLRX5	HAMP	HEPHL1	HFE	HJV	HMOX1	HPX	IREB2	ISCU	MECR	MT-RNR2	MYC	NCOA4	NDFIP1	NUBP1	PICALM	RBX1	SCARA5	SKP1	SLC11A1	SLC11A2	SLC22A17	SLC39A14	SLC39A8	SLC40A1	SLC46A1	SMAD1	SMAD4	SMAD5	SMAD9	SOD1	TF	TFR2	TFRC	TMPRSS6	VMA12	VMA22
KE2187_Opening_voltage_gated_calcium_channels_GO:0070588	calcium ion transmembrane transport	AFG3L2	ANO6	ANO9	ATP2A1	ATP2A2	ATP2A3	ATP2B1	ATP2B2	ATP2B3	ATP2B4	ATP2C1	ATP2C2	CACHD1	CACNA1A	CACNA1B	CACNA1C	CACNA1D	CACNA1E	CACNA1F	CACNA1G	CACNA1H	CACNA1I	CACNA1S	CACNA2D1	CACNA2D2	CACNA2D3	CACNA2D4	CACNB1	CACNB2	CACNB3	CACNB4	CACNG1	CACNG2	CACNG3	CACNG4	CACNG5	CACNG6	CACNG7	CACNG8	CALHM1	CALHM3	CATSPER1	CATSPER2	CATSPER3	CATSPER4	CCL19	CCL21	CCL3	CCR5	CCR7	CHERP	CHRNA10	CHRNA7	CHRNA9	CNGA1	CNGA2	CNGA3	CNGA4	CNGB1	CUL5	DDIT3	DRD2	EDN1	EDNRA	EDNRB	ERO1A	F2R	FAIM2	FASLG	FGF2	FLNA	GAS6	GHITM	GP1BA	GP1BB	GP5	GP9	GPM6A	GRIN1	GRIN2A	GRIN2B	GRIN2C	GRIN2D	GRIN3A	GRIN3B	GRINA	HSPA9	HTR2A	HTR2B	HTR2C	IBTK	ITGAV	ITPR1	ITPR2	ITPR3	JPH1	JPH2	JPH3	JPH4	LCK	LETM1	LETM2	MAIP1	MCOLN1	MCOLN2	MCOLN3	MCU	MCUB	MCUR1	MICU1	MICU2	MICU3	NALCN	NALF1	NALF2	NCS1	NOL3	OPRM1	ORAI1	ORAI2	ORAI3	P2RX1	P2RX2	P2RX3	P2RX4	P2RX5	P2RX6	P2RX7	PANX1	PANX3	PKD1	PKD1L1	PKD1L2	PKD1L3	PKD2	PKD2L1	PKD2L2	PKDREJ	PLCB1	PLCB2	PLCB3	PLCB4	PLCE1	PLCG1	PLCG2	PLCH1	PLCH2	PLCL1	PLCL2	PMPCB	PSEN1	PTPRC	RYR1	RYR2	RYR3	SCN11A	SEC61A1	SLC24A1	SLC24A2	SLC24A3	SLC24A4	SLC24A5	SLC25A23	SLC30A1	SLC35G1	SLC8A1	SLC8A2	SLC8A3	SLC8B1	SMDT1	STIM2	TMBIM1	TMBIM4	TMBIM6	TMC1	TMC2	TMCO1	TMEM165	TMEM37	TMEM38A	TMEM38B	TMEM65	TPCN1	TPCN2	TRDN	TRPA1	TRPC1	TRPC3	TRPC4	TRPC4AP	TRPC5	TRPC6	TRPC7	TRPM1	TRPM2	TRPM3	TRPM4	TRPM5	TRPM6	TRPM7	TRPM8	TRPV1	TRPV2	TRPV3	TRPV4	TRPV5	TRPV6	VDAC1	WNT3A	XCL1
KE2188_Activation_caspases_GO:0097190	apoptotic signaling pathway	ABL1	ACVR1B	ACVR1C	ADORA1	AEN	AIFM1	ANXA6	APAF1	ARL6IP5	ATF2	ATF4	ATM	ATP2A1	ATP2A3	BAD	BAG3	BAG6	BAK1	BAX	BBC3	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L2	BCL3	BID	BIRC2	BIRC3	BLOC1S2	BNIP3	BNIP3L	BOK	BRCA1	BRSK2	BTK	CARD8	CARD9	CASP2	CASP3	CASP4	CASP6	CASP8	CASP8AP2	CASP9	CAV1	CD24	CD27	CD38	CD70	CDIP1	CDKN1A	CEBPB	CFLAR	CHAC1	CHEK2	CIB1	CIDEB	CLEC7A	CLU	COA8	CRADD	CRH	CRIP1	CUL1	CUL2	CUL3	CUL4A	CUL5	CYCS	CYP1B1	DAB2IP	DAP	DAP3	DAPK1	DAPL1	DAXX	DDIT3	DDIT4	DDX3X	DDX47	DDX5	DEDD	DEDD2	DELE1	DIABLO	DIDO1	DNAJC10	DPF2	DYRK2	E2F1	EP300	EPHA2	ERBB3	ERN1	ERN2	ERO1A	FADD	FAS	FASLG	FASTK	FGFR3	FHIT	FNIP2	FZD9	G0S2	GABARAP	GGCT	GSK3A	GSK3B	GSKIP	HIC1	HINT1	HIP1	HIP1R	HIPK1	HIPK2	HSPE1	HTRA2	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFNG	IKBKE	IL12A	IL6R	INHBA	ITGAV	ITPR1	JAK2	JMY	LAPTM5	LGALS12	LOC122513141	MAP2K4	MAP3K5	MCL1	MLLT11	MOAP1	MSH6	MYBBP1A	NFKBIZ	NGF	NGFR	NLRP1	NODAL	NOL3	P2RX4	P2RX7	PAWR	PDCD10	PDCD6	PDE3A	PDK1	PDK2	PDPK1	PHLDA3	PMAIP1	PML	POU4F1	POU4F2	PPARD	PPP1R13B	PPP1R15A	PRKCA	PRKCD	PRKDC	PRODH	PTGIS	PTH	PYCARD	QRICH1	RHOT1	RHOT2	RIPK1	RIPK3	RNF186	RNF41	RPS27L	RRP8	RTL10	SCN2A	SELENOK	SFN	SGPL1	SHH	SIRT1	SIVA1	SLFN12	SMAD3	SMAD4	SNW1	SOD2	SORT1	SPI1	SST	SSTR3	ST20	STK11	STK24	STK25	SYK	TFPT	TGFB1	TGFB2	TIMM50	TLR3	TM2D1	TMEM109	TMEM117	TMEM238L	TNF	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF1A	TNFRSF1B	TNFRSF25	TNFSF10	TNFSF12	TOPORS	TP53	TP53BP2	TP63	TP73	TRADD	TRAF2	TRAF5	TRIB3	UACA	UBE4B	URI1	USP28	VDAC2	XBP1	ZDHHC3	ZNF385B	ZNF622
KE2195_Increase_CNS_Neural_cell_death_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE2201_Agonism_Retinoic_acid_receptor_GO:0048384	retinoic acid receptor signaling pathway	ACTN4	ESRRG	NCOA3	NR1H2	PPARG	PTF1A	RARA	RARB	RARG	RXRA	RXRB	RXRG	SNW1	TBX1	THRA	THRB	VDR
KE2202_Altered_expression_of_cell_cycle_genes_GO:0000278	mitotic cell cycle	AAAS	ABCB1	ABL1	ABRAXAS1	ABRAXAS2	ACVR1B	AFG2B	AKAP8	AKAP8L	ANAPC1	ANAPC11	ANAPC2	ANK3	ANKFN1	ANKLE2	ANKRD53	ANLN	APC	ARF1	ARHGEF10	ARL3	ARPP19	ATF2	ATM	ATR	AURKA	AURKB	AURKC	BABAM1	BABAM2	BANF1	BAP1	BARD1	BBS4	BCAT1	BCCIP	BECN1	BIRC5	BLM	BOD1	BRCA1	BRCA2	BRCC3	BROX	BRSK1	BRSK2	BUB1	BUB1B	BUB3	CACUL1	CAMK2A	CCDC57	CCDC61	CCDC66	CCDC86	CCNA1	CCNA2	CCNB1	CCNB2	CCNB3	CCND1	CCND2	CCND3	CCNE1	CCNE2	CCNF	CCNG1	CCNG2	CCNI	CCNI2	CCNJ	CCNJL	CCNO	CCNP	CCNY	CDC14B	CDC20	CDC23	CDC25A	CDC25B	CDC25C	CDC27	CDC34	CDC45	CDC6	CDC7	CDCA8	CDK1	CDK10	CDK11A	CDK11B	CDK14	CDK2	CDK3	CDK4	CDK5RAP2	CDK5RAP3	CDK6	CDKN1A	CDKN1B	CDKN3	CDT1	CENPA	CENPC	CENPE	CENPF	CENPH	CENPI	CENPK	CENPT	CENPW	CEP126	CEP192	CEP250	CEP55	CETN2	CFL1	CHAMP1	CHEK1	CHEK2	CHFR	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4BP1	CHMP4C	CHMP5	CHMP6	CHMP7	CIB1	CIT	CKAP2	CKAP5	CLASP1	CLASP2	CLIP1	CLSPN	CLTC	CLTCL1	CNTROB	CTDNEP1	CTDP1	CUL1	CUL2	CUL3	CUL4A	CUL4B	CUL5	CUL7	DBF4	DCTN1	DCTN2	DCTN3	DCTN6	DIS3L2	DLGAP5	DNA2	DNM2	DONSON	DTL	DYNC1H1	DYNLT1	E2F3	E2F8	ECT2	EDNRA	EFHC1	EIF4E	EIF4EBP1	EME1	EME2	EML1	EML3	EML4	ENKD1	ENSA	EPS8	ESPL1	ETAA1	EXOC1	EXOC2	EXOC3	EXOC4	EXOC5	EXOC6	EXOC6B	EXOC7	EXOC8	FAM110A	FANCD2	FBXL15	FBXL7	FBXO31	FBXW11	FIRRM	FLNA	FOXM1	FOXN3	FZR1	GEM	GINS1	GJA1	GOLGA2	GPR132	GPSM1	GPSM2	GSPT1	H3-3A	H3-5	H3-7	H3Y1	H3Y2	HASPIN	HDAC3	HGF	HINFP	HTT	HUS1	HUS1B	IER3IP1	IK	ILK	INCENP	INIP	INO80	INPPL1	INTS13	INTS3	IQGAP1	IQGAP2	IQGAP3	IST1	ITGB1	JTB	KAT5	KATNB1	KDM8	KHDRBS1	KIF11	KIF14	KIF15	KIF18A	KIF18B	KIF20A	KIF22	KIF23	KIF25	KIF2A	KIF2C	KIF3B	KIF4A	KIF4B	KIFC1	KLHDC8B	KLHL22	KMT5A	KNL1	KNSTRN	KNTC1	KPNB1	LATS1	LATS2	LCMT1	LIG1	LPIN1	LSM14A	LZTS2	MAD1L1	MAD2L1	MAD2L2	MAP10	MAP1S	MAP4	MAP9	MAPRE1	MASTL	MBTPS1	MBTPS2	MCM2	MCM3	MCM4	MCM6	MCPH1	MDC1	MELK	MIS12	MISP	MITD1	MNAT1	MRE11	MRNIP	MTMR3	MTMR4	MUC1	MUS81	MYB	MYBL1	MYBL2	MYC	MYH10	MYH14	MZT1	NAA50	NABP1	NABP2	NAE1	NBN	NCAPD2	NCAPD3	NCAPG	NCAPG2	NCAPH	NCAPH2	NDC80	NDE1	NDEL1	NEDD1	NEK11	NEK2	NEK3	NEK4	NEK6	NEK9	NES	NIPBL	NOLC1	NOP53	NRDE2	NSFL1C	NSL1	NUDC	NUDT15	NUF2	NUMA1	NUP62	NUSAP1	ORC1	PABIR1	PAFAH1B1	PBK	PBRM1	PCNA	PCNT	PDCD6IP	PHF13	PHF8	PIAS1	PIBF1	PIM2	PINX1	PKHD1	PKMYT1	PLCB1	PLK1	PLK2	PLK3	PLK5	POLA1	POLDIP2	POLE	PPME1	PPP1CC	PPP1R12A	PPP2CA	PPP2CB	PPP2R2D	PPP5C	PPP6C	PRC1	PRDM5	PRICKLE1	PRKCA	PRKCB	PRKDC	PSRC1	PTPA	PTPN6	RAB11A	RAB35	RAB6C	RACGAP1	RAD17	RAD21	RAD50	RAD51	RAD9A	RAD9B	RAN	RANGRF	RASA1	RBBP8	RBX1	RCC1	RECQL5	REEP3	REEP4	RFWD3	RHOA	RHOB	RHOC	RINT1	RMDN1	ROCK1	ROCK2	RPA2	RPS27L	RPS6KB1	RRS1	RTEL1	RTKN	SAPCD2	SBDS	SDE2	SEH1L	SEPTIN6	SETD2	SETDB2	SETMAR	SIRT2	SKA1	SKA2	SKA3	SKP1	SKP2	SMC1A	SMC2	SMC3	SMC4	SNX18	SNX33	SNX9	SON	SPAG5	SPART	SPAST	SPC24	SPC25	SPDL1	SPDYA	SPICE1	SPTBN1	STAG1	STAG2	STAMBP	STIL	STK33	STMN1	SUN2	TACC1	TACC2	TACC3	TAF2	TAOK1	TAOK2	TAOK3	TBCD	TBCE	TENT4A	TEX14	TICRR	TIMELESS	TIPIN	TK1	TNKS	TOPBP1	TP53	TPD52L1	TPR	TPX2	TRIAP1	TRIM36	TRIM39	TRIM71	TRIP13	TTC19	TTK	TTN	TUBA1A	TUBA1B	TUBA1C	TUBA3C	TUBA3D	TUBA3E	TUBA4A	TUBA8	TUBAL3	TUBB	TUBB1	TUBB2A	TUBB2B	TUBB3	TUBB4A	TUBB4B	TUBB6	TUBB8	TUBB8B	TUBD1	TUBE1	TUBG1	TUBG2	TUBGCP2	TUBGCP3	TUBGCP4	TUBGCP5	TUBGCP6	UBE2A	UBE2C	UBE2I	UBE2S	UBXN2B	UHRF1	UIMC1	UNC119	USH1C	USP16	USP22	USP26	USP29	USP37	USP8	VCP	VPS4A	VPS4B	VRK1	WAC	WAPL	WDHD1	WDR62	WEE1	WEE2	WRAP73	XRCC2	YEATS4	ZFYVE19	ZFYVE26	ZNF207	ZNF324	ZNF830	ZNRD2	ZW10	ZWILCH	ZWINT
KE2203_Decreased_proliferation_of_cortical_neural_progenitor_cells_GO:0061351	neural precursor cell proliferation	AKNA	ARHGEF2	ARTN	ATF5	CEP120	DBN1	DCT	DISC1	DIXDC1	DOCK7	EML1	EPHB1	FGF13	FGFR1	FGFR2	HEATR1	HOOK3	KCNA1	KIF14	MELK	MIOS	NDUFS2	NFIB	NUMB	NUMBL	PAFAH1B1	PCM1	PLXNB2	RAB10	RACGAP1	RORA	SHH	SIX3	SLC39A5	SOX5	TEAD3	TMEM14B	TRIM3	TRNP1	WNT1	WNT2	WNT3A	WNT7A	ZNF503
KE2204_Altered_brain_morphology_GO:0048854	brain morphogenesis	BBS2	BBS4	CTNNA2	FBXW11	FZD3	FZD6	MKKS	NF1	PAFAH1B1	PAX2	PTEN	SHANK3	SLC6A4	SLIT1	SMO	SPEF2	TUBA1A	UCHL5	VPS51
KE2208_Aberrant_synaptic_formation_and_plasticity_GO:0007416	synapse assembly	ACHE	ADD2	ADGRF1	ADGRL2	ADGRL3	AKAP5	BDNF	BSN	C1QL2	C1QL3	CBLN4	CDH1	CDH2	CDK5	CLSTN2	CNTN5	CRK	CRKL	CSMD2	DAG1	DBNL	DNER	DNM3	DRD1	DRD2	DSCAM	DVL1	EFNB2	EGFLAM	EPHB2	ERBB4	FARP1	FBXO45	FGF13	FLRT3	FZD1	FZD5	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB2	GABRB3	GABRE	GABRG1	GABRG2	GABRG3	GPHN	GPM6A	GRIA1	GRID2	HAPLN4	IL1RAPL1	KIRREL3	LGI2	LRP4	LRRC4	MAP1B	MYCBP2	NLGN1	NLGN2	NLGN3	NLGN4X	NLGN4Y	NPAS4	NPTX1	NRCAM	NRG3	NRXN1	NRXN2	NRXN3	NTNG2	NTRK3	PCDH17	PCDHB10	PCDHB11	PCDHB13	PCDHB14	PCDHB16	PCDHB2	PCDHB3	PCDHB4	PCDHB5	PCDHB6	PCDHB9	PCLO	PLXNA1	PLXNA2	PLXNA3	PLXNA4	PLXNB1	PLXNB2	PLXNB3	PLXNC1	PLXND1	POU4F1	PTEN	PTPRD	RAB29	RELN	RYK	SDK1	SDK2	SHANK2	SHANK3	SKP1	SLITRK1	SLITRK6	SPOCK2	SRGAP2	SRGAP2C	VSIG10	WNT3A	WNT5A	WNT7A	ZDHHC12	ZDHHC2
KE2208_Aberrant_synaptic_formation_and_plasticity_GO:0048167	regulation of synaptic plasticity	ABL1	ACE	ACP4	ADCY1	ADCY8	ADGRB1	ADORA1	ADORA2A	AGER	AKAP5	ANAPC2	APOE	APP	ARC	ARF1	ATF4	BEST1	BRSK1	C22orf39	CALB1	CALB2	CALHM2	CALM1	CALM2	CALM3	CAMK2A	CAMK2B	CAMK2D	CAMK2G	CBLN1	CD38	CDC20	CDK5	CFL1	CHRDL1	CHRNA7	CLN3	CNTN4	CPEB3	CPLX2	CREB1	CRH	CRHR2	CX3CL1	CX3CR1	CYP46A1	DBN1	DLG4	DRD2	EIF2AK4	EIF4EBP2	ELOVL4	EPHA4	EPHB2	F2R	FAM107A	FMR1	FXR1	FXR2	GIPC1	GRIA1	GRIA3	GRID1	GRID2	GRIK2	GRIN1	GRIN2A	GRIN2B	GRIN2C	GRIN2D	GRIN3A	GRIN3B	GRM5	GSK3B	IGSF11	INS	IQSEC2	JPH3	JPH4	KAT2A	KCNB1	KIT	LGMN	LILRB2	LZTS1	MAP1A	MAP1B	MAPT	MCTP1	MEF2C	MME	MPP2	NCDN	NETO1	NEURL1	NEUROD2	NFATC4	NOG	NPAS4	NPTN	NRGN	NSG1	NSMF	NTRK2	PDE9A	PICK1	PLK2	PPFIA3	PPP3CB	PRKAR1B	PRKCG	PRKCZ	PRNP	PRRT1	PRRT2	PTK2B	PTN	RAB11A	RAB3A	RAB3GAP1	RAB5A	RAB8A	RAPGEF2	RARA	RASGRF1	RELN	RGS14	S100B	SCT	SCTR	SHANK2	SHANK3	SHISA6	SHISA7	SHISA8	SHISA9	SIPA1L1	SLC18A3	SLC24A1	SLC24A2	SLC38A1	SLC4A10	SLC8A2	SLC8A3	SORCS2	SORCS3	SQSTM1	SSH1	STAU1	STAU2	STX4	SYAP1	SYNGAP1	SYNGR1	SYP	SYT12	SYT4	SYT7	TSHZ3	TYROBP	UBE3A	UNC13C	VAMP2	VGF	YTHDF1	YWHAG	YWHAH	ZDHHC2
KE2210_Reduced_cortical_thickness_GO:0021987	cerebral cortex development	ADGRG1	AKIRIN2	ARHGAP11B	ATIC	BBS2	BBS4	BNIP3	BTBD3	CCDC85C	CDK5R1	CNTNAP2	COL3A1	CSNK2A2	DAB1	DAB2IP	DISC1	DIXDC1	EFHC1	EOMES	FAT4	FGF13	FLNA	FOS	FOXP2	GART	GRIA1	GSK3B	HTR6	KCNA2	KDM1A	KIF14	KIF26A	LAMB1	LHX6	MBOAT7	MCPH1	MDK	MGARP	MKKS	NARS1	NCAPG2	NCAPH2	NCOA1	NDE1	NDEL1	NEFL	NF1	NOTCH2NLA	NOTCH2NLB	NOTCH2NLC	NPY	NSUN5	NTRK2	P2RY12	PAFAH1B1	PALS1	PAX6	PEX13	PHACTR1	PLCB1	PPP1R9B	RELN	ROBO1	RTN4	SLC2A1	SLC38A2	SLIT2	SMC2	SMC4	SOCS7	SRD5A1	SRGAP2	SRGAP2C	SUN1	SUN2	SYNE2	TACC1	TACC2	TACC3	TBR1	TMEM14B	TRAPPC9	TUBA1A	TUBB2A	TUBB2B	WDR62	XAB2	ZMIZ1
KE2216_Binding_of_antagonist_to_thyroid_hormone_receptor_GO:0002154	thyroid hormone receptor signaling pathway	MED1	THRA	THRB
KE2217_Binding_of_antagonist_to_glucocorticoid_hormone_receptor_GO:0042921	nuclear receptor-mediated glucocorticoid signaling pathway	CALR	NEDD4	NR3C1	YWHAH
KE2218_Binding_of_ant_agonist_to_liver_X_receptor_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE2219_Binding_of_ant_agonist_to_peroxisome_proliferatoractivated_receptor_alpha_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE2220_Antagonism_Glucocorticoid_hormone_receptor_GO:0042921	nuclear receptor-mediated glucocorticoid signaling pathway	CALR	NEDD4	NR3C1	YWHAH
KE2221_Altered_Liver_X_receptor_activity_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE2222_Altered_peroxisome_proliferatoractivated_receptor_alpha_activity_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE2223_Reduced_number_of_oligodendrocytes_GO:0048709	oligodendrocyte differentiation	ABCA2	B4GALT5	B4GALT6	BNIP3	BOK	CD9	CDK5	CDKN2C	CERS5	CFH	CLU	CNTN1	CNTNAP1	CSK	EIF2B1	EIF2B2	EIF2B3	EIF2B4	EIF2B5	GPM6B	GPR17	GSTP1	HES5	LPAR1	LYN	MAG	MIOS	MYRF	NOTCH1	NSUN5	NTRK2	OLIG1	OLIG2	PLP1	PRDM8	PTEN	PTPRZ1	SHH	SLC8A3	SOX10	SOX11	SOX13	SOX6	SOX8	SOX9	TENM4	TGFB1	TPPP	VTN	ZNF488
KE2223_Reduced_number_of_oligodendrocytes_GO:0070444	oligodendrocyte progenitor proliferation	MIOS
KE2232_Antagonism_Retinoic_acid_receptors_GO:0048384	retinoic acid receptor signaling pathway	ACTN4	ESRRG	NCOA3	NR1H2	PPARG	PTF1A	RARA	RARB	RARG	RXRA	RXRB	RXRG	SNW1	TBX1	THRA	THRB	VDR
KE2233_Decreased_ER_heterodimers_GO:0030520	estrogen receptor signaling pathway	AR	CCDC62	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	NCOA1	NCOA4	PADI2	POU4F2	PPARGC1B	RBFOX2	SAFB	TADA3	TRIP4
KE2262_Neuropathy_target_esterase_inhibited_GO:0006644	phospholipid metabolic process	ABCA2	ABCA3	ABCA8	ABHD12	ABHD12B	ABHD16A	ABHD16B	ABHD3	ABHD4	ABHD5	ABHD6	ABHD8	ACAT2	ACP6	AGPAT1	AGPAT2	AGPAT3	AGPAT4	AGPAT5	ALOX15	ALOX15B	ANGPTL3	APOA1	APOA2	APOA4	ATG14	ATM	BECN1	BMX	BPNT1	BPNT2	CDIPT	CDS1	CDS2	CEPT1	CERS5	CERT1	CETP	CHAT	CHKA	CHKB	CHPT1	CLN3	CLN8	CPNE1	CPNE3	CPNE6	CPNE7	CRLS1	CWH43	CYP2W1	DBI	DDHD1	DEGS1	DGKA	DGKB	DGKD	DGKE	DGKG	DGKH	DGKI	DGKK	DGKQ	DGKZ	DHDDS	DHRSX	DOLK	DOLPP1	DPM1	DPM2	DPM3	EFR3A	EFR3B	ENPP2	ENPP6	ENPP7	ETNK1	ETNK2	FADS1	FAR1	FDFT1	FDPS	FIG4	FITM1	FITM2	FLVCR1	GALR2	GDE1	GDPD1	GDPD2	GDPD3	GGPS1	GNPAT	GPAA1	GPAM	GPAT2	GPAT3	GPAT4	GPCPD1	GPX4	HADHA	HDHD5	HMGCR	HMGCS1	HMGCS2	HYCC1	HYCC2	IDI1	IDI2	IMPA1	IMPA2	INPP1	INPP4A	INPP4B	INPP5A	INPP5B	INPP5D	INPP5E	INPP5F	INPP5J	INPP5K	INPPL1	IP6K1	IP6K2	IP6K3	IPMK	ISYNA1	ITPKA	ITPKB	ITPKC	KDSR	LCAT	LCLAT1	LGALS13	LIPC	LIPG	LIPH	LIPI	LPCAT1	LPCAT2	LPCAT3	LPCAT4	LPGAT1	LPIN1	LPL	MBOAT1	MBOAT2	MBOAT7	MFSD2A	MPPE1	MTM1	MTMR1	MTMR12	MTMR14	MTMR2	MTMR3	MTMR4	MTMR6	MTMR7	MTMR8	MTMR9	MVD	MVK	NAAA	NAPEPLD	NR1H2	NR1H3	NUS1	OC90	OCRL	OSBP	OSBPL10	OSBPL5	OSBPL8	PAFAH1B1	PAFAH1B2	PAFAH1B3	PCTP	PCYT1A	PCYT1B	PCYT2	PEMT	PGAP1	PGAP2	PGAP3	PGAP4	PGP	PGS1	PI4K2A	PI4K2B	PI4KA	PI4KAP2	PI4KB	PIGA	PIGB	PIGC	PIGF	PIGG	PIGH	PIGK	PIGL	PIGM	PIGN	PIGO	PIGP	PIGQ	PIGS	PIGT	PIGU	PIGV	PIGW	PIGX	PIGY	PIGZ	PIK3C2A	PIK3C2B	PIK3C2G	PIK3C3	PIK3CA	PIK3CB	PIK3CD	PIK3CG	PIK3R1	PIK3R3	PIK3R4	PIK3R5	PIKFYVE	PIP4K2A	PIP4K2B	PIP4K2C	PIP4P1	PIP4P2	PIP5K1A	PIP5K1B	PIP5K1C	PIP5KL1	PIPSL	PISD	PITPNC1	PITPNM1	PITPNM2	PITPNM3	PLA1A	PLA2G10	PLA2G12A	PLA2G12B	PLA2G15	PLA2G1B	PLA2G2A	PLA2G2C	PLA2G2D	PLA2G2E	PLA2G2F	PLA2G3	PLA2G4A	PLA2G4B	PLA2G4C	PLA2G4D	PLA2G4E	PLA2G4F	PLA2G5	PLA2G6	PLA2G7	PLAA	PLAAT1	PLAAT2	PLAAT3	PLAAT4	PLAAT5	PLB1	PLCB1	PLCB2	PLCB3	PLCB4	PLCD1	PLCE1	PLCG1	PLCG2	PLCH1	PLCH2	PLCL1	PLCL2	PLD1	PLD2	PLD6	PLEKHA1	PLEKHA3	PLEKHA4	PLEKHA8	PLPP1	PLPP2	PLPP3	PLPP4	PLPP5	PLPP6	PLPPR1	PLPPR2	PLPPR3	PLPPR4	PLPPR5	PLSCR1	PMVK	PNLIPRP2	PNPLA3	PNPLA6	PNPLA7	PNPLA8	PON1	PPARD	PRDX6	PROCA1	PTDSS1	PTDSS2	PTEN	PTPMT1	PTPRQ	RUFY1	SACM1L	SAMD8	SBF1	SELENOI	SERAC1	SERINC1	SERINC2	SERINC4	SERINC5	SGMS1	SGMS2	SLC30A5	SLC44A1	SLC44A2	SLC44A3	SLC44A4	SLC44A5	SMG1	SMPD1	SMPD2	SMPD3	SMPD4	SMPDL3B	SPHK2	SPTLC1	SPTLC2	SPTSSA	SRD5A3	STARD10	STARD7	SYNJ1	SYNJ2	TAFAZZIN	TAMM41	TMEM150A	TMEM86B	TNFAIP8L3	TPTE2	TTC7A	TTC7B	UVRAG	VAC14	VAPA
KE2263_Lysolecithin_increased_GO:0006644	phospholipid metabolic process	ABCA2	ABCA3	ABCA8	ABHD12	ABHD12B	ABHD16A	ABHD16B	ABHD3	ABHD4	ABHD5	ABHD6	ABHD8	ACAT2	ACP6	AGPAT1	AGPAT2	AGPAT3	AGPAT4	AGPAT5	ALOX15	ALOX15B	ANGPTL3	APOA1	APOA2	APOA4	ATG14	ATM	BECN1	BMX	BPNT1	BPNT2	CDIPT	CDS1	CDS2	CEPT1	CERS5	CERT1	CETP	CHAT	CHKA	CHKB	CHPT1	CLN3	CLN8	CPNE1	CPNE3	CPNE6	CPNE7	CRLS1	CWH43	CYP2W1	DBI	DDHD1	DEGS1	DGKA	DGKB	DGKD	DGKE	DGKG	DGKH	DGKI	DGKK	DGKQ	DGKZ	DHDDS	DHRSX	DOLK	DOLPP1	DPM1	DPM2	DPM3	EFR3A	EFR3B	ENPP2	ENPP6	ENPP7	ETNK1	ETNK2	FADS1	FAR1	FDFT1	FDPS	FIG4	FITM1	FITM2	FLVCR1	GALR2	GDE1	GDPD1	GDPD2	GDPD3	GGPS1	GNPAT	GPAA1	GPAM	GPAT2	GPAT3	GPAT4	GPCPD1	GPX4	HADHA	HDHD5	HMGCR	HMGCS1	HMGCS2	HYCC1	HYCC2	IDI1	IDI2	IMPA1	IMPA2	INPP1	INPP4A	INPP4B	INPP5A	INPP5B	INPP5D	INPP5E	INPP5F	INPP5J	INPP5K	INPPL1	IP6K1	IP6K2	IP6K3	IPMK	ISYNA1	ITPKA	ITPKB	ITPKC	KDSR	LCAT	LCLAT1	LGALS13	LIPC	LIPG	LIPH	LIPI	LPCAT1	LPCAT2	LPCAT3	LPCAT4	LPGAT1	LPIN1	LPL	MBOAT1	MBOAT2	MBOAT7	MFSD2A	MPPE1	MTM1	MTMR1	MTMR12	MTMR14	MTMR2	MTMR3	MTMR4	MTMR6	MTMR7	MTMR8	MTMR9	MVD	MVK	NAAA	NAPEPLD	NR1H2	NR1H3	NUS1	OC90	OCRL	OSBP	OSBPL10	OSBPL5	OSBPL8	PAFAH1B1	PAFAH1B2	PAFAH1B3	PCTP	PCYT1A	PCYT1B	PCYT2	PEMT	PGAP1	PGAP2	PGAP3	PGAP4	PGP	PGS1	PI4K2A	PI4K2B	PI4KA	PI4KAP2	PI4KB	PIGA	PIGB	PIGC	PIGF	PIGG	PIGH	PIGK	PIGL	PIGM	PIGN	PIGO	PIGP	PIGQ	PIGS	PIGT	PIGU	PIGV	PIGW	PIGX	PIGY	PIGZ	PIK3C2A	PIK3C2B	PIK3C2G	PIK3C3	PIK3CA	PIK3CB	PIK3CD	PIK3CG	PIK3R1	PIK3R3	PIK3R4	PIK3R5	PIKFYVE	PIP4K2A	PIP4K2B	PIP4K2C	PIP4P1	PIP4P2	PIP5K1A	PIP5K1B	PIP5K1C	PIP5KL1	PIPSL	PISD	PITPNC1	PITPNM1	PITPNM2	PITPNM3	PLA1A	PLA2G10	PLA2G12A	PLA2G12B	PLA2G15	PLA2G1B	PLA2G2A	PLA2G2C	PLA2G2D	PLA2G2E	PLA2G2F	PLA2G3	PLA2G4A	PLA2G4B	PLA2G4C	PLA2G4D	PLA2G4E	PLA2G4F	PLA2G5	PLA2G6	PLA2G7	PLAA	PLAAT1	PLAAT2	PLAAT3	PLAAT4	PLAAT5	PLB1	PLCB1	PLCB2	PLCB3	PLCB4	PLCD1	PLCE1	PLCG1	PLCG2	PLCH1	PLCH2	PLCL1	PLCL2	PLD1	PLD2	PLD6	PLEKHA1	PLEKHA3	PLEKHA4	PLEKHA8	PLPP1	PLPP2	PLPP3	PLPP4	PLPP5	PLPP6	PLPPR1	PLPPR2	PLPPR3	PLPPR4	PLPPR5	PLSCR1	PMVK	PNLIPRP2	PNPLA3	PNPLA6	PNPLA7	PNPLA8	PON1	PPARD	PRDX6	PROCA1	PTDSS1	PTDSS2	PTEN	PTPMT1	PTPRQ	RUFY1	SACM1L	SAMD8	SBF1	SELENOI	SERAC1	SERINC1	SERINC2	SERINC4	SERINC5	SGMS1	SGMS2	SLC30A5	SLC44A1	SLC44A2	SLC44A3	SLC44A4	SLC44A5	SMG1	SMPD1	SMPD2	SMPD3	SMPD4	SMPDL3B	SPHK2	SPTLC1	SPTLC2	SPTSSA	SRD5A3	STARD10	STARD7	SYNJ1	SYNJ2	TAFAZZIN	TAMM41	TMEM150A	TMEM86B	TNFAIP8L3	TPTE2	TTC7A	TTC7B	UVRAG	VAC14	VAPA
KE2264_Lysolecithin_cell_membrane_integration_increased_GO:0061024	membrane organization	A4GALT	AAK1	ABCA1	ABCA12	ABCA2	ABCA3	ABCA4	ABCA7	ABCB1	ABCB4	ABCC1	ABCD1	ABCD2	ABCG1	ACE2	ADGRB1	AGK	AGRN	AIF1	AKAP8L	ALKBH4	ANK2	ANK3	ANKFY1	ANKLE2	ANO3	ANO4	ANO5	ANO6	ANO7	ANO9	ANXA2	ANXA7	AP2M1	AP3B2	AP3D1	AP3M2	AP3S1	AP3S2	APOE	APOO	APOOL	ARF1	ARFGAP2	ARFGAP3	ARHGAP12	ARHGAP25	ARL6IP1	ARL8B	ARV1	ATG2A	ATG2B	ATG9A	ATG9B	ATL1	ATL2	ATL3	ATP10A	ATP10B	ATP10D	ATP11A	ATP11B	ATP11C	ATP13A2	ATP1B1	ATP2C1	ATP8A1	ATP8A2	ATP8B1	ATP8B2	ATP8B3	ATP8B4	ATP9A	ATP9B	ATR	AURKB	AZIN2	BAG6	BAIAP2	BAIAP2L1	BAIAP2L2	BANF1	BCS1L	BECN1	BET1	BET1L	BIN1	BIN2	BIN3	BLTP1	BLTP3B	BNIP1	BROX	BTBD8	C2CD2L	C9orf72	CALM3	CAMLG	CAV1	CAV2	CAV3	CAVIN2	CCDC47	CCDC88A	CD2	CD24	CD36	CDC42	CDH2	CDK1	CEP55	CERS2	CERT1	CHCHD10	CHCHD3	CHCHD6	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4BP1	CHMP4C	CHMP5	CHMP6	CHMP7	CHP1	CHRDL1	CHRNB1	CIBAR1	CIDEA	CIDEB	CIDEC	CLCN2	CLN3	CLPTM1L	CLTRN	CLU	CNTN2	CNTNAP2	COL5A1	COLEC12	CORO1C	COX18	CPTP	CR1	CSNK1D	CTDNEP1	CTSL	CUL3	CXCR4	DBNL	DCSTAMP	DCTN1	DEGS1	DES	DLG4	DMKN	DMPK	DNAJA3	DNAJC11	DNM1	DNM1L	DNM2	DNM3	DOCK1	DPP4	EEA1	EGFR	EHD2	ELMO1	EMC1	EMC10	EMC2	EMC3	EMC4	EMC6	EMC7	EMC8	EMC9	EMD	EMP2	EPB41L3	EPHB2	ESYT1	EXOC1	EXOC2	EXOC3	EXOC4	EXOC5	EXOC6	EXOC6B	EXOC7	EXOC8	FA2H	FABP1	FASLG	FCGR1A	FCHO2	FCHSD1	FCHSD2	FER1L5	FLOT1	FNBP1L	FNTA	GAS6	GBA2	GBF1	GCA	GET1	GET3	GET4	GHITM	GLTP	GLTPD2	GOLPH3	GOLPH3L	GOSR1	GOSR2	GPER1	GPHN	GRIN3B	GSN	GULP1	HACE1	HAVCR1	HDAC3	HGS	HILPDA	HIP1R	HSD17B13	HSPA8	HSPA9	HUWE1	ICA1	ICA1L	IL1RAPL1	ILK	IMMT	IQGAP1	IRAG2	IST1	ITGAM	ITGB2	KCNB1	KCNIP2	KIF20A	KLHL12	LEMD2	LETM1	LHFPL4	LMNA	LMNB1	LMNB2	LPCAT2	LPCAT3	LPIN1	LRCH4	LRP4	LRRC4	MAFB	MAIP1	MAL	MAPK15	MARCO	MEGF10	MFN2	MFSD2A	MIA3	MICALL1	MICALL2	MICOS10	MICOS13	MITD1	MMGT1	MOAP1	MSR1	MTCH1	MTCH2	MTMR3	MTMR4	MTSS1	MTSS2	MTTP	MTX1	MTX2	MTX3	MUSK	MVB12A	MX1	MX2	MYADM	MYH9	MYO18A	MYOC	MYOF	MYRF	NAPA	NAPG	NAXE	NCLN	NDRG1	NDRG4	NDUFA13	NECTIN2	NEK6	NEMP1	NHERF1	NKD2	NLGN1	NLGN2	NLGN3	NLGN4X	NME3	NME4	NOMO1	NOMO2	NOMO3	NPC1	NRCAM	NRXN1	NRXN2	NSFL1C	NUP155	NUP93	OCRL	OPA1	OSBP	OSBPL10	OSBPL11	OSBPL2	OSBPL5	OSBPL6	OSBPL8	OSBPL9	OTOF	OXA1L	P2RX7	PACSIN1	PACSIN2	PACSIN3	PADI4	PALS1	PDCD6	PDCD6IP	PEF1	PICALM	PICK1	PIK3C2A	PIKFYVE	PIP4K2A	PIP4K2B	PIP5K1C	PITPNA	PITPNB	PITPNC1	PITPNM1	PITPNM2	PITPNM3	PLA2G5	PLAAT3	PLEC	PLEKHA8	PLEKHA8P1	PLEKHM1	PLK1	PLSCR1	PLSCR2	PLSCR3	PLSCR4	PLSCR5	PLTP	PMP2	PPP6C	PPT1	PREB	PRELID1	PRELID2	PRELID3A	PRELID3B	PRKCA	PRKCB	PRKCI	PRRT2	PRX	PTEN	PTPRC	PTPRD	RAB14	RAB1A	RAB20	RAB2A	RAB34	RAB39A	RAB3A	RAB4B	RAB5IF	RAB7A	RAB7B	RAB8A	RABEP1	RABIF	RAC1	RAPSN	RCC1	REEP1	REEP3	REEP4	REEP5	RELN	RFT1	RFTN1	RHOA	RILP	RILPL1	RILPL2	RIMS1	ROMO1	RTN1	RTN2	RTN3	RTN4	RTP1	RTP2	RTP3	RTP4	RTP5	RUBCNL	RUFY1	RUFY4	S100A10	SAMD9	SAMM50	SAR1A	SAR1B	SCAP	SCLT1	SEC13	SEC16A	SEC22A	SEC22B	SEC23A	SEC23B	SEC24A	SEC24B	SEC24C	SEC24D	SEC31A	SEC31B	SEC61A1	SERINC2	SERINC3	SERINC5	SERP1	SGCZ	SGTA	SH3BP1	SH3GL1	SH3GL2	SH3GL3	SH3GLB1	SH3GLB2	SHANK3	SHISA7	SIRT2	SLC25A46	SLC66A2	SMPD1	SMURF1	SNAP23	SNAP25	SNAP29	SNAP47	SNAP91	SNCA	SNF8	SNX1	SNX18	SNX3	SNX33	SNX5	SNX9	SOD1	SOX30	SPART	SPAST	SPG11	SPIRE1	SPIRE2	SPTBN1	SPTBN4	STAM	STAM2	STARD7	STEEP1	STX10	STX11	STX12	STX16	STX17	STX18	STX19	STX1A	STX1B	STX2	STX3	STX4	STX5	STX6	STX7	STX8	STXBP1	STXBP6	SURF4	SYNGR1	SYNGR2	SYNJ1	SYNJ2	SYP	SYT1	SYT11	SYT4	SYT7	SYTL4	TAFAZZIN	TARDBP	TBC1D20	TFG	TGFBRAP1	THBS1	TIMD4	TIMM10	TIMM10B	TIMM13	TIMM22	TIMM29	TIMM50	TIMM8A	TIMM8B	TIMM9	TLCD1	TLCD2	TMCC1	TMCO1	TMED10	TMED2	TMED9	TMEM11	TMEM126A	TMEM147	TMEM170A	TMEM175	TMEM30A	TMEM30B	TMEM33	TMEM41B	TMEM43	TMEM63B	TNFAIP8L3	TOM1	TOMM20	TOMM22	TOMM40	TOMM5	TOMM6	TOMM7	TOMM70	TOR1A	TOR1AIP1	TOR1AIP2	TOR1B	TRAM1	TRAM1L1	TRAM2	TRAPPC1	TRAPPC10	TRAPPC11	TRAPPC12	TRAPPC13	TRAPPC2	TRAPPC2B	TRAPPC2L	TRAPPC3	TRAPPC4	TRAPPC5	TRAPPC6A	TRAPPC6B	TRAPPC8	TRAPPC9	TRDN	TRIAP1	TRIM72	TRMT10B	TRPC5	TSG101	TSNARE1	TTPA	UBAP1	UBE2I	UBL4A	UBXN2A	UBXN2B	UGCG	UQCC3	USE1	USO1	UVRAG	VAMP1	VAMP2	VAMP3	VAMP4	VAMP7	VAMP8	VAPA	VAPB	VAT1	VCPIP1	VDAC2	VIPAS39	VMP1	VPS11	VPS16	VPS18	VPS25	VPS28	VPS33A	VPS33B	VPS36	VPS37A	VPS37B	VPS37C	VPS37D	VPS39	VPS41	VPS4A	VPS4B	VPS8	VRK1	VTI1A	VTI1B	WASL	WDR83OS	WHAMM	WNK1	XKR4	XKR6	XKR7	XKR8	YIPF4	YIPF5	YIPF7	YJEFN3	YKT6	ZFYVE19	ZFYVE26	ZMPSTE24
KE1214_Altered_gene_expression_specific_to_CAR_activation_Hepatocytes_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE25_Agonism_Androgen_receptor_GO:0030521	androgen receptor signaling pathway	AR	CST11	DAXX	DDX17	DDX5	KDM3A	KDM4C	NKX3-1	PARK7	PLPP1	PMEPA1	RHOXF1	RNF14	RWDD1	SCGB2A1	SCGB2A2	TMF1	ZDHHC7	ZMIZ1
KE18_Activation_AhR_GO:0030522	intracellular receptor signaling pathway	ABHD2	ACTN4	AHR	AHRR	ALOXE3	ALPK1	AR	ARNT	BECN1	CALCOCO1	CALR	CARD8	CCDC62	CGAS	CLPB	CRY1	CRY2	CST11	CYLD	CYP24A1	DAXX	DCBLD2	DDX17	DDX3X	DDX41	DDX5	DDX54	DEFA1	DEFA3	DHX58	EGLN2	EPG5	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HAVCR2	HDAC2	HNF4A	HNF4G	IFIH1	IKBKB	INAVA	IPO5	IRAK1	IRAK2	IRAK4	IRF1	IRF2	IRF3	IRF5	IRF7	IRGM	ITCH	JAK2	KDM3A	KDM4C	LACC1	MAP2K6	MAP3K7	MAVS	MED1	MYD88	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NLRP1	NLRP3	NLRP6	NOD1	NOD2	NR1D1	NR1D2	NR1H2	NR1H3	NR1H4	NR1I2	NR1I3	NR2C1	NR2C2	NR2E1	NR2E3	NR2F1	NR2F2	NR2F6	NR3C1	NR3C2	NR4A1	NR4A2	NR4A3	NR5A1	NR5A2	NR6A1	OAS1	OAS3	OR51E2	OTULIN	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PHB2	PIK3AP1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	PYCARD	RARA	RARB	RARG	RBFOX2	RELA	RFTN1	RHOXF1	RIGI	RIPK2	RNF135	RNF14	RNF34	RORA	RORB	RORC	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SCIMP	SNW1	SRC	SREBF1	STAT3	STING1	TADA3	TBK1	TBX1	THRA	THRB	TICAM1	TIFA	TLR3	TLR7	TLR8	TLR9	TMF1	TNF	TNFAIP3	TNIP2	TRAF3IP3	TRAF6	TRERF1	TRIM25	TRIP4	UBE3A	UBR5	UNC93B1	VDR	WBP2	XIAP	YWHAE	YWHAH	ZDHHC7	ZMIZ1
KE280_Thyroxine_T4_in_neuronal_tissue_Decreased_GO:0042403	thyroid hormone metabolic process	CPQ	CRYM	CTSB	CTSK	DIO1	DIO2	DIO3	DUOX1	DUOX2	FOXE1	IYD	SLC16A2	SLC26A7	SLC5A5	SULT1A1	SULT1A3	SULT1A4	SULT1B1	SULT2A1	TG	TPO
KE280_Thyroxine_T4_in_neuronal_tissue_Decreased_GO:0070327	thyroid hormone transport	CRYM	SERPINA7	SLC16A10	SLC16A2	SLC17A4	SLC3A2	SLC7A5	SLC7A8	SLCO1B1	SLCO1C1	SLCO4A1	TUBB1
KE402_Cognitive_function_decreased_GO:0050890	cognition	ABCA7	ABCC8	ABL1	ACSS2	ADCY3	ADCY8	ADNP	ADORA1	AGER	AMFR	APOE	APP	ARC	ATAD1	ATP8A1	ATXN1	ATXN1L	B2M	BBS4	BCHE	BGLAP	BRSK1	C12orf57	C5AR1	CALB1	CAMK2N1	CAMK4	CARTPT	CASP3	CBR3	CCL11	CEBPB	CHD7	CHMP2B	CHRFAM7A	CHRM1	CHRNA4	CHRNA7	CHRNB2	CIC	CLDN5	CLN3	CLSTN2	CNTNAP2	CPEB3	CREB1	CRH	CRHBP	CTNS	CUX2	CYFIP1	DCANP1	DEAF1	DGCR2	DKK1	DLG4	DOP1B	DRD1	DRD2	DRD3	EGFR	EGR1	EIF2AK4	EIF4A3	EIF4EBP2	EN1	EP300	EPHB2	FAM107A	FEN1	FGF13	FOS	FOXB1	FOXO6	FYN	GALR2	GALR3	GATM	GHSR	GIT1	GLP1R	GPI	GPR155	GPR158	GPR88	GPRASP3	GRIA1	GRIN1	GRIN2A	GRIN2B	GRM5	GRPR	GTF2A1L	HLA-DRA	HOXA1	HTR2A	HTT	INS	INSR	JAKMIP1	JPH3	KAT2A	KAT2B	KCNK2	KCNK4	KIT	KLK8	LCE1D	LCN2	LDLR	LGMN	LHCGR	LILRB2	LINS1	LRRN4	MAGT1	MAP1A	MAPK1	MAPK8IP2	MAPT	MDK	MECP2	MEF2C	METTL23	MFSD2A	MGAT3	MME	MUSK	NDRG4	NEDD9	NETO1	NEUROG1	NF1	NFATC4	NIPBL	NLGN3	NLGN4X	NLGN4Y	NOG	NPAS4	NRGN	NRXN1	NRXN2	NRXN3	NSUN5	NTF4	NTRK1	NTRK2	NTSR1	OPRK1	OR52B4	OXT	PAFAH1B1	PGRMC1	PIAS1	PICALM	PJA2	PLCB1	PLK2	PLN	PPP1R9B	PPP3CB	PRKCA	PRKCG	PRNP	PSEN1	PTCHD1	PTEN	PTN	PTPRZ1	RAG1	RAPGEF3	RASGRF1	RELN	RGS14	RP9	S100B	SCN2A	SERPINF1	SETD5	SGK1	SHANK1	SHANK2	SHANK3	SHISA7	SHROOM4	SIGMAR1	SLC1A1	SLC1A4	SLC2A4	SLC6A1	SLC6A4	SLC8A2	SLC8A3	SOBP	SRF	ST3GAL4	STRA6	SYNJ1	SYT11	SYT4	TAAR5	TAC1	TACR1	TACR2	TACR3	TAFA2	TH	TIFAB	TLR2	TMPRSS11E	TNF	TREM2	TSC1	TTBK1	TTC8	TUBA1A	TUSC3	UCN	VLDLR	YTHDF1
KE122_Activation_Glucocorticoid_Receptor_GO:0042921	nuclear receptor-mediated glucocorticoid signaling pathway	CALR	NEDD4	NR3C1	YWHAH
KE202_Inhibition_Nuclear_factor_kappa_B_NF_kB_GO:0007249	canonical NF-kappaB signal transduction	ADAM8	BCL3	BIRC2	BIRC3	CARD11	CHUK	CREBBP	EP300	HACD3	IKBKB	IKBKG	IRAK1	IRAK2	IRAK4	MAP3K7	MYD88	NFKB1	NFKB2	NFKBIA	NLRC3	NOD2	NPM1	PRDX4	REL	RELA	RELB	RIPK1	RIPK2	TAB1	TAB2	TAB3	TBK1	TLR7	TLR8	TLR9	TRADD	TRAF6	TRIM8
KE1493_Increased_Pro_inflammatory_mediators_GO:0002532	production of molecular mediator involved in inflammatory response	ADAM17	BTK	CAMP	CD36	CHIA	FADS2	FCER1G	IL4R	LYN	SLC18A2	SNAP23	SYK
KE1494_Leukocyte_recruitment_activation_GO:0030595	leukocyte chemotaxis	ADAM8	ADGRE2	ALOX5	ANXA1	AZU1	BSG	CALCA	CCL1	CCL11	CCL13	CCL16	CCL19	CCL2	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR5	CCR6	CCR7	CD300H	CD4	CH25H	CHGA	CKLF	CORO1C	CTSG	CX3CL1	CX3CR1	CXADR	CXCL10	CXCL11	CXCL13	CXCL16	CXCL17	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR1	CXCR2	CXCR3	CXCR4	CYP7B1	DEFA1	DEFB104A	DPEP1	EDN2	EDN3	EDNRB	FCER1G	FFAR2	FLT1	GAS6	GBF1	GPR15LG	GPR183	GPR25	GPR35	HMGB1	HSD3B7	IL10	IL17RA	IL17RC	IL6	IL6R	ITGB2	JAML	KIT	LGALS3	LYST	MDK	MMP2	MSMP	MT-RNR2	NINJ1	PDE4B	PDGFB	PF4	PF4V1	PIK3CD	PIK3CG	PIKFYVE	PIP5K1C	PLA2G1B	PLEC	PPBP	PPIA	PPIB	PTN	PTPRO	RPS19	S100A12	S100A8	S100A9	SAA1	SBDS	SCG2	SFTPD	SLAMF8	SLC12A2	SRP54	SYK	TAFA4	TGFB2	TNFRSF11A	TNFSF11	TREM1	TRPM2	TRPM4	XCL1
KE1494_Leukocyte_recruitment_activation_GO:0045321	leukocyte activation	ADA	ADAM10	ADAM17	ADAM9	ADGRG3	AGER	AICDA	AIF1	AIRE	AKAP17A	ANXA1	ANXA3	APP	AQP8	ASCL2	ATF2	ATM	ATP7A	AXL	AZU1	BAG6	BANK1	BATF	BATF2	BATF3	BCL2	BLNK	BST2	BTK	BTN3A1	BTNL3	BTNL8	C17orf99	C1QA	C3	C5AR1	CAMK4	CAMP	CASP8	CBL	CCL19	CCL21	CCL3	CCL5	CCR6	CCR7	CD180	CD19	CD1C	CD1D	CD2	CD209	CD22	CD244	CD247	CD27	CD276	CD28	CD38	CD3D	CD3E	CD3G	CD4	CD40	CD40LG	CD44	CD48	CD6	CD7	CD70	CD74	CD79A	CD79B	CD80	CD81	CD84	CD86	CD8A	CD8B	CD93	CDH17	CDH26	CEACAM21	CEBPG	CHD7	CHGA	CHRNA4	CHRNB2	CLCF1	CLEC2A	CLEC2B	CLEC2D	CLEC4A	CLEC7A	CLNK	CLU	CORO1A	CPLX2	CR2	CRTAM	CRTC3	CSF1	CSF2	CTPS1	CTSG	CTSL	CUL4A	CX3CL1	CX3CR1	CXADR	CXCL6	CXCL8	CXCR1	CXCR2	CXCR5	DCAF1	DCAF12	DCSTAMP	DDOST	DHRS2	DLL1	DLL4	DNAJB9	DNASE1	DNASE1L3	DOCK10	DOCK11	DOCK2	DOCK8	DPP4	DYSF	EBI3	EDN1	EDN2	EIF2AK4	ELF4	EMP2	ENPP3	ENTPD7	EOMES	EPHB2	EXOSC3	EXOSC6	EZH2	F2RL1	FADD	FCER1A	FCER1G	FCER2	FCGR2B	FCGR3A	FCRL1	FCRL5	FKBP1A	FLT3	FLT3LG	FNIP1	FOXN1	FOXP1	FOXP3	FPR2	FYN	GAPT	GATA3	GLI3	GNAI1	GNAQ	GPR15LG	GPR183	GPR89A	GPR89B	GPS2	GRB2	GRN	GRP	HAVCR2	HDAC4	HDAC5	HDAC9	HELLS	HHEX	HLA-A	HLA-E	HMGB1	HSH2D	HSPD1	HYAL2	ICAM1	ICAM3	ICOS	ICOSLG	IFI35	IFNA10	IFNA14	IFNA16	IFNA17	IFNA2	IFNA21	IFNA4	IFNA5	IFNA6	IFNA7	IFNA8	IFNB1	IFNE	IFNG	IFNGR1	IFNGR2	IFNK	IFNW1	IGBP1	IGHE	IKZF1	IKZF3	IL10	IL11	IL12B	IL13	IL15	IL18	IL18R1	IL18RAP	IL1RAP	IL2	IL21	IL21R	IL2RG	IL33	IL4	IL6	IL6R	IL6ST	INS	IRF2BP2	IRF4	IRF8	ITGA4	ITGAL	ITGAM	ITGB1	ITGB2	ITK	JAG2	JAK1	JAK2	JAK3	JAML	JMJD1C	KARS1	KAT7	KIF13B	KIR3DS1	KIT	KLF6	KLRC1	KLRF1	KLRF2	KLRK1	KMT2A	KMT2E	LAG3	LAT	LAT2	LAX1	LBP	LCK	LCP1	LCP2	LEF1	LEP	LEPR	LFNG	LGALS9	LIG4	LILRA2	LILRB1	LMBR1L	LRRC8A	LTBR	LY6D	LY9	LYL1	LYN	MALT1	MAPT	MDK	MEF2C	MEN1	MFNG	MICA	MICB	MILR1	MR1	MRGPRX2	MS4A1	MSH2	MSH6	MSN	MT1G	MTOR	MYB	MYC	NBN	NCAPH	NCK1	NCK2	NCR1	NCR3	NCR3LG1	NFAM1	NFATC3	NFE2L2	NFIL3	NFKBIZ	NHEJ1	NKG7	NLRC3	NMI	NOTCH2	NPY	NR4A3	PAX5	PBX1	PCYT1A	PDP2	PECAM1	PHB1	PHB2	PHF14	PIK3CD	PIK3CG	PIK3R1	PIK3R2	PIK3R3	PLA2G3	PLCG2	PLXNA1	POU2AF1	PPP3CA	PPP3CB	PRDM16	PRDX1	PRDX2	PREX1	PRF1	PRG3	PRKCB	PRKCD	PRR7	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB10	PSMB11	PSMB2	PSMB3	PSMB4	PSMB8	PSMB9	PTCRA	PTGDR	PTGDS	PTGER4	PTK2B	PTPN2	PTPN22	PTPN6	PTPRC	PTPRJ	PYCARD	RAB29	RAB44	RABL3	RAG1	RAG2	RASGRP1	RBX1	RELB	RHOA	RHOH	RIPK3	RNF168	RNF8	RORA	RORC	RSAD2	S100A12	S100A13	SANBR	SBNO2	SCART1	SCN11A	SCRIB	SELPLG	SEMA4A	SEMA6D	SH2D1A	SH2D1B	SH2D2A	SHH	SKAP2	SLA2	SLAMF1	SLAMF6	SLAMF7	SLAMF8	SLAMF9	SLC11A1	SLC18A2	SLC25A5	SLC39A6	SLC39A7	SMAD3	SMC2	SMC4	SNAP23	SNCA	SNX27	SOCS3	SOS1	SOX13	SOX4	SPACA3	SPI1	SPIB	SPN	ST3GAL1	STAT3	STAT4	STK39	STOML2	STXBP2	STXBP3	SYK	SYVN1	TBK1	TBX21	TCF3	TCF7	TGFB1	TGFBR2	THEMIS	TLR1	TLR4	TLR6	TLR9	TMEM106A	TMEM98	TNF	TNFRSF14	TNFRSF4	TNFSF13B	TNFSF14	TNFSF18	TNFSF4	TNFSF8	TOLLIP	TOP2B	TOX	TPD52	TRAC	TRAF2	TRAF3IP2	TRBC1	TRBC2	TRDC	TREM2	TREML2	TRGC1	TYROBP	UBD	ULBP1	ULBP2	ULBP3	USP44	VAMP2	VAMP7	VAV1	VCAM1	WNK4	YY1	ZAP70	ZBTB16	ZBTB46	ZBTB7A	ZBTB7B	ZFP36L1	ZFP36L2	ZFPM1	ZNF3
KE265_Activation_Stellate_cells_GO:0035733	hepatic stellate cell activation	AKAP12	GCLM
KE1492_Tissue_resident_cell_activation_GO:0001775	cell activation	ACTB	ACTG1	ADA	ADAM10	ADAM17	ADAM9	ADAMTS13	ADGRG3	ADORA2A	ADRA2A	ADRA2B	ADRA2C	AGER	AICDA	AIF1	AIRE	AKAP12	AKAP17A	ANXA1	ANXA3	APP	AQP8	ASCL2	ASTL	ATF2	ATM	ATP7A	AXL	AZU1	BAG6	BANK1	BATF	BATF2	BATF3	BCL2	BLNK	BLOC1S3	BMPER	BST2	BTK	BTN3A1	BTNL3	BTNL8	C17orf99	C1QA	C3	C5AR1	CAMK4	CAMP	CASP8	CBL	CCL19	CCL21	CCL3	CCL5	CCR6	CCR7	CD180	CD19	CD1C	CD1D	CD2	CD209	CD22	CD24	CD244	CD247	CD27	CD276	CD28	CD38	CD3D	CD3E	CD3G	CD4	CD40	CD40LG	CD44	CD48	CD6	CD7	CD70	CD74	CD79A	CD79B	CD80	CD81	CD84	CD86	CD8A	CD8B	CD9	CD93	CDH17	CDH26	CEACAM21	CEBPG	CHD7	CHGA	CHRNA4	CHRNB2	CLCF1	CLEC2A	CLEC2B	CLEC2D	CLEC4A	CLEC7A	CLIC1	CLNK	CLU	CNTF	COL3A1	CORO1A	CPLX2	CR2	CRNN	CRTAM	CRTC3	CSF1	CSF2	CSRP1	CTPS1	CTSG	CTSL	CUL4A	CX3CL1	CX3CR1	CXADR	CXCL10	CXCL6	CXCL8	CXCR1	CXCR2	CXCR5	DCAF1	DCAF12	DCSTAMP	DDOST	DGKA	DGKB	DGKD	DGKE	DGKG	DGKH	DGKI	DGKK	DGKQ	DGKZ	DHRS2	DLL1	DLL4	DNAJB9	DNASE1	DNASE1L3	DOCK10	DOCK11	DOCK2	DOCK8	DPP4	DYSF	EBI3	EDN1	EDN2	EIF2AK4	ELF4	EMP2	ENPP3	ENTPD1	ENTPD7	EOMES	EPHB1	EPHB2	EXOSC3	EXOSC6	EZH2	F2	F2R	F2RL1	F2RL2	F2RL3	FADD	FCER1A	FCER1G	FCER2	FCGR2B	FCGR3A	FCRL1	FCRL5	FERMT3	FGA	FGB	FGG	FIBP	FKBP1A	FLNA	FLT3	FLT3LG	FNIP1	FOXN1	FOXP1	FOXP3	FPR2	FYN	GAPT	GATA1	GATA3	GBF1	GCLM	GLI3	GNAI1	GNAQ	GNAS	GP1BA	GP1BB	GP6	GPR15LG	GPR183	GPR89A	GPR89B	GPS2	GRB2	GRN	GRP	HAVCR2	HBB	HDAC4	HDAC5	HDAC9	HELLS	HHEX	HLA-A	HLA-E	HMGB1	HOXA9	HRG	HSH2D	HSPB1	HSPD1	HYAL2	ICAM1	ICAM3	ICOS	ICOSLG	IFI35	IFNA10	IFNA14	IFNA16	IFNA17	IFNA2	IFNA21	IFNA4	IFNA5	IFNA6	IFNA7	IFNA8	IFNB1	IFNE	IFNG	IFNGR1	IFNGR2	IFNK	IFNW1	IGBP1	IGF1	IGHE	IKZF1	IKZF3	IL10	IL11	IL12B	IL13	IL15	IL17A	IL17RA	IL18	IL18R1	IL18RAP	IL1RAP	IL2	IL21	IL21R	IL2RG	IL33	IL4	IL6	IL6R	IL6ST	ILK	INS	IRF2BP2	IRF4	IRF8	ITGA4	ITGAL	ITGAM	ITGB1	ITGB2	ITGB3	ITK	ITPR3	JAG2	JAK1	JAK2	JAK3	JAML	JMJD1C	KARS1	KAT7	KIF13B	KIR3DS1	KIT	KLF6	KLRC1	KLRF1	KLRF2	KLRK1	KMT2A	KMT2E	KRT2	LAG3	LAT	LAT2	LAX1	LBP	LCK	LCP1	LCP2	LEF1	LEP	LEPR	LFNG	LGALS9	LIG4	LILRA2	LILRB1	LMBR1L	LRP1	LRRC8A	LTBR	LY6D	LY9	LYL1	LYN	MALT1	MAPK14	MAPT	MDK	MDM2	MEF2C	MEGF10	MEN1	METAP1	MFNG	MICA	MICB	MILR1	MR1	MRGPRX2	MS4A1	MSH2	MSH6	MSN	MT1G	MTOR	MYB	MYC	MYH9	MYL12A	MYL9	NBN	NCAPH	NCK1	NCK2	NCR1	NCR3	NCR3LG1	NFAM1	NFATC3	NFE2L2	NFIL3	NFKBIZ	NHEJ1	NKG7	NLRC3	NLRP5	NMI	NOTCH2	NPR2	NPY	NR4A3	P2RX4	P2RY1	P2RY12	PAX5	PBX1	PCYT1A	PDGFA	PDGFRA	PDP2	PDPN	PEAR1	PECAM1	PF4	PHB1	PHB2	PHF14	PIK3CA	PIK3CB	PIK3CD	PIK3CG	PIK3R1	PIK3R2	PIK3R3	PLA2G3	PLAT	PLCB1	PLCG2	PLCZ1	PLEK	PLSCR1	PLXNA1	POU2AF1	PPIA	PPP3CA	PPP3CB	PRDM16	PRDX1	PRDX2	PREX1	PRF1	PRG3	PRKCB	PRKCD	PRMT5	PRR7	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB10	PSMB11	PSMB2	PSMB3	PSMB4	PSMB8	PSMB9	PTCRA	PTGDR	PTGDS	PTGER4	PTK2B	PTPN2	PTPN22	PTPN6	PTPRC	PTPRJ	PYCARD	RAB29	RAB44	RABL3	RAG1	RAG2	RAP2B	RASA3	RASGRP1	RBX1	RELB	RGCC	RHOA	RHOH	RIPK3	RNF168	RNF8	RORA	RORC	RSAD2	S100A12	S100A13	SAA1	SANBR	SBNO2	SCART1	SCN11A	SCRIB	SELPLG	SEMA4A	SEMA6D	SH2D1A	SH2D1B	SH2D2A	SHH	SKAP2	SLA2	SLAMF1	SLAMF6	SLAMF7	SLAMF8	SLAMF9	SLC11A1	SLC18A2	SLC25A5	SLC39A6	SLC39A7	SLC6A4	SLURP1	SMAD3	SMAD4	SMC2	SMC4	SNAP23	SNCA	SNX27	SOCS3	SOS1	SOX13	SOX4	SPACA3	SPI1	SPIB	SPN	SRC	ST3GAL1	STAT3	STAT4	STK39	STOML2	STXBP1	STXBP2	STXBP3	SYK	SYVN1	TBK1	TBX21	TCF3	TCF7	TCIM	TGFB1	TGFBR1	TGFBR2	THEMIS	TLN1	TLR1	TLR4	TLR6	TLR9	TMEM106A	TMEM98	TNF	TNFRSF14	TNFRSF4	TNFSF13B	TNFSF14	TNFSF18	TNFSF4	TNFSF8	TOLLIP	TOP2B	TOX	TPD52	TRAC	TRAF2	TRAF3IP2	TRBC1	TRBC2	TRDC	TREM2	TREML1	TREML2	TRGC1	TUBB1	TYRO3	TYROBP	UBASH3B	UBD	ULBP1	ULBP2	ULBP3	ULK3	USP44	VAMP2	VAMP7	VAV1	VAV2	VAV3	VCAM1	VCL	VWF	WBP2NL	WNK4	XIRP1	YY1	ZAP70	ZBTB16	ZBTB46	ZBTB7A	ZBTB7B	ZEB2	ZFP36L1	ZFP36L2	ZFPM1	ZNF3	ZNF416	ZP1	ZP2	ZP4
KE1262_Apoptosis_GO:0006915	apoptotic process	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CEACAM5	CEACAM6	CEBPB	CECR2	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FNIP2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA2	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLLN	KMT2A	KREMEN1	KRT20	LALBA	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NISCH	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NUAK2	NUDT2	OGT	OPA1	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNW1	SOD2	SORT1	SPI1	SPIN2B	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1394_Induction_persistent_proliferation_sustained_proliferation_GO:0008283	cell population proliferation	ABCB1	ABL1	ACE	ACVR1C	ACVRL1	AKNA	AKT1	ALKBH3	ANG	ANKRD45	AREG	ARHGEF2	ARIH2	ARTN	ATAD5	ATF2	ATF5	ATOH8	BAD	BAP1	BCL2	BGLAP	BMP10	BMP2	BMP4	BMP7	BMPER	BMPR2	BOP1	BRAT1	BTBD10	BTK	BTN3A1	C6orf89	CCN3	CD180	CD19	CD209	CD34	CD40	CD40LG	CD70	CD79A	CDC25A	CDC25C	CDH13	CDK3	CDK5RAP3	CDK9	CEACAM1	CEBPA	CEBPB	CEMP1	CEP120	CER1	CITED2	CLDN18	CLEC12B	CLU	CNTNAP2	COL3A1	CR2	CRK	CSF1	CSF1R	CTPS1	CUL4A	CUL4B	CX3CL1	DBN1	DCAF4	DCT	DDB1	DDIT3	DDR2	DDX41	DIO3	DIPK2A	DISC1	DIXDC1	DLG1	DLX3	DLX5	DMRT1	DOCK7	DOCK8	DSG2	DUX4L9	EBI3	EDNRA	EEF2	EGR1	ELAVL1	ELF4	EML1	EMP2	ENPEP	EPHA2	EPHB1	ERBB2	EREG	ERN1	ETV6	F2RL1	FABP4	FABP7	FAM83A	FAM83B	FAM83D	FAP	FBXW8	FERMT1	FES	FGF10	FGF13	FGF2	FGF4	FGF7	FGFR1	FGFR2	FGFR3	FGL1	FIGNL1	FLT3	FOS	FOXC1	GAPT	GLUL	GPC3	GSTP1	HEATR1	HELLS	HMGA2	HMGB1	HMOX1	HOOK3	HSPD1	ICAM3	ID2	IFNB1	IGF1	IGFBP5	IL10	IL17A	IL33	IL34	IL6	IRF2	ITGB1BP1	JUND	KANK1	KCNA1	KIF14	KIT	KLK8	KRAS	KRT2	LARP1	LIG4	LILRB1	LMBR1L	LOXL2	LTK	LYN	MAP4K1	MECOM	MEF2C	MEGF10	MELK	MIOS	MKI67	MMP14	MRPS27	MS4A1	MSN	MSX1	MT-RNR1	MTSS1	MUS81	MUSTN1	MVP	MYB	MYC	NAA35	NAA60	NDRG4	NDUFS2	NELFB	NES	NF2	NFIB	NFKBIZ	NKX3-1	NKX6-1	NMB	NOG	NOTCH1	NOX5	NPPC	NPR2	NPR3	NR4A3	NRARP	NUMB	NUMBL	OGFOD1	OR51E2	OSR1	OSR2	OTUD6B	PAFAH1B1	PAK5	PCM1	PCYT1A	PDGFRB	PDK1	PDS5B	PENK	PES1	PIK3CG	PLXNB2	POC1B	POLDIP2	POLR3G	PPARD	PPP3CB	PRDX1	PRKX	PROK1	PROK2	PTPRC	RAB10	RACGAP1	RASGRP1	RBX1	RETNLB	RHBDF1	RNF43	ROR1	RORA	RPS6KA1	RUNX1	RUNX2	SCRIB	SDCBP2	SDR16C5	SEMA5A	SERPINB1	SETMAR	SFRP2	SHH	SIX2	SIX3	SKI	SLAMF1	SLC11A1	SLC20A1	SLC26A2	SLC2A4	SLC39A5	SOX11	SOX4	SOX5	SOX9	SQSTM1	STAT1	STC1	TBCK	TBX1	TBX2	TEAD3	TEK	TGFA	TGFB2	TGFBI	TGFBR1	TGFBR3	THAP1	THPO	TMEM14B	TNFRSF14	TNFRSF4	TNFSF14	TNFSF18	TREM2	TRIM3	TRIM71	TRNP1	TWIST1	TYK2	UBE2L3	USP13	USP28	USPL1	VAV1	WNT1	WNT10B	WNT16	WNT2	WNT2B	WNT3	WNT3A	WNT5A	WNT7A	WNT7B	XBP1	YAP1	YJEFN3	YME1L1	YPEL5	YTHDF2	YY1AP1	ZEB2	ZNF324	ZNF416	ZNF503	ZNRF3	ZPR1
KE41_Inhibition_Bile_Salt_Export_Pump_ABCB11_GO:0015722	canalicular bile acid transport	ABCB11
KE115_Increase_FA_Influx_GO:0015908	fatty acid transport	ABCC4	ABCD1	ABCD2	ABCD3	ABCD4	ACE	ACSL1	ACSL3	APOE	BDKRB2	CD36	CPT1A	CPT1B	CPT2	CRABP1	CRABP2	DRD2	DRD3	DRD4	FABP1	FABP12	FABP2	FABP3	FABP4	FABP5	FABP5P3	FABP6	FABP7	FABP9	GOT2	LEP	LYN	LYPLA1	MFSD2A	NMB	NMUR2	NOS2	OC90	PLA2G10	PLA2G12A	PLA2G12B	PLA2G1B	PLA2G2A	PLA2G2C	PLA2G2D	PLA2G2E	PLA2G2F	PLA2G3	PLA2G4A	PLA2G5	PMP2	PNPLA8	PPARD	PPARG	PROCA1	RBP1	RBP2	RBP5	RBP7	RPS6KB1	SLC22A1	SLC22A11	SLC22A2	SLC22A6	SLC22A7	SLC22A8	SLC22A9	SLC25A17	SLC25A20	SLC27A1	SLC27A2	SLC27A3	SLC27A4	SLC27A5	SLC27A6	SLC2A1	SLC43A3	SLC5A8	SLCO1B1	SLCO2A1	SLCO2B1	SLCO3A1	SLCO4A1	SPX	THRSP	UCP2
KE116_Activation_FAS_GO:0006633	fatty acid biosynthetic process	ABCD1	ABCD2	ABCD3	ABHD1	ABHD2	ABHD3	ACACA	ACACB	ACLY	ACOT4	ACOT7	ACOT8	ACOX1	ACSBG1	ACSBG2	ACSF3	ACSL1	ACSL4	ACSM1	ACSM2A	ACSM2B	ACSM3	ACSM4	ACSM5	ACSM6	ACSS1	ACSS2	AKR1C3	ALOX12	ALOX12B	ALOX15	ALOX15B	ALOX5	ALOXE3	ASAH2	BRCA1	CBR1	CBR4	CD74	CTHRC1	CYP1A1	CYP1A2	CYP2C8	CYP2C9	CYP2D6	CYP2E1	CYP3A4	DAGLB	DECR2	DEGS1	EHHADH	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	FA2H	FADS1	FADS2	FADS2B	FADS3	FADS6	FASN	GPX4	GSTM1	GSTM2	GSTM4	GSTP1	HACD1	HACD2	HACD3	HACD4	HPGDS	HSD17B12	HSD17B4	HSD17B8	HTD2	LIAS	LIPC	LIPG	LPL	LTC4S	MCAT	MECR	MGLL	MIF	MLYCD	NDUFAB1	OLAH	OXSM	PECR	PLA2G10	PLA2G1B	PLA2G4A	PNLIP	PNLIPRP1	PNLIPRP2	PNLIPRP3	PNPLA8	PRKAA1	PRKAA2	PRKAB1	PRKAB2	PRKAG1	PRKAG2	PRKAG3	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGS1	PTGS2	SCD	SCD5	SCP2	SIGMAR1	TBXAS1	TECR	TECRL	TMEM135	XBP1
KE228_peroxisome_proliferator_activated_receptor_promoter_demethylation_GO:0141166	chromosomal 5-methylcytosine DNA demethylation pathway	A1CF	APOBEC1	HNRNPAB	TDG
KE258_Activation_SCD_1_GO:0006636	unsaturated fatty acid biosynthetic process	AKR1C3	ALOX12	ALOX15	ALOX15B	CBR1	CD74	CTHRC1	DAGLB	DECR2	DEGS1	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	FADS1	FADS2	FADS2B	FADS3	HPGDS	MIF	PLA2G10	PLA2G4A	PNPLA8	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGS1	PTGS2	SCD	SCD5	SIGMAR1	TBXAS1
KE264_Activation_SREBP_1c_GO:0032933	SREBP signaling pathway	ARHGEF10L	ERLIN1	ERLIN2	INSIG1	INSIG2	SCAP	SREBF1	SREBF2
KE54_Up_Regulation_CD36_GO:0015908	fatty acid transport	ABCC4	ABCD1	ABCD2	ABCD3	ABCD4	ACE	ACSL1	ACSL3	APOE	BDKRB2	CD36	CPT1A	CPT1B	CPT2	CRABP1	CRABP2	DRD2	DRD3	DRD4	FABP1	FABP12	FABP2	FABP3	FABP4	FABP5	FABP5P3	FABP6	FABP7	FABP9	GOT2	LEP	LYN	LYPLA1	MFSD2A	NMB	NMUR2	NOS2	OC90	PLA2G10	PLA2G12A	PLA2G12B	PLA2G1B	PLA2G2A	PLA2G2C	PLA2G2D	PLA2G2E	PLA2G2F	PLA2G3	PLA2G4A	PLA2G5	PMP2	PNPLA8	PPARD	PPARG	PROCA1	RBP1	RBP2	RBP5	RBP7	RPS6KB1	SLC22A1	SLC22A11	SLC22A2	SLC22A6	SLC22A7	SLC22A8	SLC22A9	SLC25A17	SLC25A20	SLC27A1	SLC27A2	SLC27A3	SLC27A4	SLC27A5	SLC27A6	SLC2A1	SLC43A3	SLC5A8	SLCO1B1	SLCO2A1	SLCO2B1	SLCO3A1	SLCO4A1	SPX	THRSP	UCP2
KE233_Decreased_PPAR_gamma_activation_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE165_Activation_Long_term_AHR_receptor_driven_direct_and_indirect_gene_expression_changes_GO:0030522	intracellular receptor signaling pathway	ABHD2	ACTN4	AHR	AHRR	ALOXE3	ALPK1	AR	ARNT	BECN1	CALCOCO1	CALR	CARD8	CCDC62	CGAS	CLPB	CRY1	CRY2	CST11	CYLD	CYP24A1	DAXX	DCBLD2	DDX17	DDX3X	DDX41	DDX5	DDX54	DEFA1	DEFA3	DHX58	EGLN2	EPG5	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HAVCR2	HDAC2	HNF4A	HNF4G	IFIH1	IKBKB	INAVA	IPO5	IRAK1	IRAK2	IRAK4	IRF1	IRF2	IRF3	IRF5	IRF7	IRGM	ITCH	JAK2	KDM3A	KDM4C	LACC1	MAP2K6	MAP3K7	MAVS	MED1	MYD88	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NLRP1	NLRP3	NLRP6	NOD1	NOD2	NR1D1	NR1D2	NR1H2	NR1H3	NR1H4	NR1I2	NR1I3	NR2C1	NR2C2	NR2E1	NR2E3	NR2F1	NR2F2	NR2F6	NR3C1	NR3C2	NR4A1	NR4A2	NR4A3	NR5A1	NR5A2	NR6A1	OAS1	OAS3	OR51E2	OTULIN	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PHB2	PIK3AP1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	PYCARD	RARA	RARB	RARG	RBFOX2	RELA	RFTN1	RHOXF1	RIGI	RIPK2	RNF135	RNF14	RNF34	RORA	RORB	RORC	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SCIMP	SNW1	SRC	SREBF1	STAT3	STING1	TADA3	TBK1	TBX1	THRA	THRB	TICAM1	TIFA	TLR3	TLR7	TLR8	TLR9	TMF1	TNF	TNFAIP3	TNIP2	TRAF3IP3	TRAF6	TRERF1	TRIM25	TRIP4	UBE3A	UBR5	UNC93B1	VDR	WBP2	XIAP	YWHAE	YWHAH	ZDHHC7	ZMIZ1
KE409_Metabolism_of_AFB1_Production_of_Reactive_Electrophiles_GO:0046222	aflatoxin metabolic process	AKR7A3	CYP1A2	CYP2A13	CYP2W1	CYP3A4	CYP3A5	NFE2L2
KE493_Increased_Insufficient_repair_or_mis_repair_of_pro_mutagenic_DNA_adducts_GO:0006281	DNA repair	A8MVJ9	ABL1	ABRAXAS1	ACTL6A	ACTR5	ACTR8	ADPRS	AGER	ALKBH1	ALKBH2	ALKBH3	ANKLE1	AP5S1	AP5Z1	APEX1	APEX2	APLF	APTX	ASCC1	ASCC2	ASCC3	ASF1A	ASTE1	ATM	ATP23	ATR	ATRIP	ATRX	ATXN3	AUNIP	BABAM1	BABAM2	BACH1	BARD1	BCCIP	BLM	BOD1L1	BRCA1	BRCA2	BRCC3	BRD9	BRIP1	BRME1	BTG2	CCNH	CDC14B	CDC45	CDC5L	CDC7	CDCA5	CDK1	CDK2	CDK7	CDK9	CDKN2D	CENPS	CENPX	CEP164	CETN2	CGAS	CHAF1A	CHAF1B	CHD1L	CHD4	CHEK1	CHEK2	CHRNA4	CIB1	CINP	CLSPN	COMMD1	CSNK1E	CSNK2A1	CSNK2A2	CSNK2A3	CTBP1-DT	CUL4A	CUL4B	CYREN	DCLRE1A	DCLRE1B	DCLRE1C	DDB1	DDB2	DDX1	DDX11	DMAP1	DMC1	DNA2	DNTT	DOT1L	DTX3L	DYRK1B	EEPD1	EID3	ELOF1	EME1	EME2	EMSY	ENDOV	EP400	EPC1	EPC2	ERCC1	ERCC2	ERCC3	ERCC4	ERCC5	ERCC6	ERCC6L	ERCC6L2	ERCC8	ETAA1	EXD2	EXO1	EXO5	EXOSC10	EYA1	EYA2	EYA3	EYA4	FAAP100	FAAP20	FAAP24	FAM111A	FAM111B	FAN1	FANCA	FANCB	FANCC	FANCD2	FANCE	FANCF	FANCG	FANCI	FANCL	FANCM	FBH1	FBXO6	FBXW7	FEN1	FH	FIGNL1	FIRRM	FMR1	FOXM1	FTO	FZR1	GADD45A	GCNA	GEN1	GGN	GINS2	GINS4	GTF2H1	GTF2H2	GTF2H2C	GTF2H3	GTF2H4	GTF2H5	H2AC25	H2AX	HDAC10	HDGFL2	HELB	HELLS	HELQ	HERC2	HINFP	HLTF	HMCES	HMGA2	HMGB1	HMGB2	HPF1	HROB	HSF1	HSF2BP	HTATSF1	HUS1	HUS1B	HUWE1	IFFO1	INIP	INO80	INO80B	INO80C	INO80D	INO80E	INTS3	JMY	KAT5	KAT7	KDM2A	KDM4D	KIF22	KIN	KMT5B	KMT5C	LIG1	LIG3	LIG4	LMNA	MACROH2A1	MAD2L2	MBD4	MBTD1	MC1R	MCM2	MCM3	MCM4	MCM5	MCM6	MCM7	MCM8	MCM9	MCMDC2	MCRS1	MDC1	MEIOB	MEIOC	MEN1	MGME1	MGMT	MLH1	MLH3	MMS19	MMS22L	MNAT1	MORF4L1	MORF4L2	MPG	MPND	MRE11	MRNIP	MSH2	MSH3	MSH4	MSH5	MSH6	MTA1	MUS81	MUTYH	NABP1	NABP2	NBN	NEIL1	NEIL2	NEIL3	NEURL4	NFRKB	NHEJ1	NIPBL	NME3	NONO	NOP53	NPM1	NSD2	NSMCE1	NSMCE2	NSMCE3	NSMCE4A	NTHL1	NUCKS1	NUDT1	OGG1	OTUB1	OTUD4	PAGR1	PALB2	PARG	PARK7	PARP1	PARP10	PARP2	PARP3	PARP4	PARP9	PARPBP	PAXIP1	PAXX	PCLAF	PCNA	PDS5B	PELI1	PIAS4	PIF1	PLK1	PMS1	PMS2	PMS2P1	PMS2P2	PMS2P3	PMS2P5	PNKP	POGZ	POLA1	POLB	POLD1	POLD2	POLD3	POLD4	POLDIP2	POLE	POLE2	POLG	POLH	POLI	POLK	POLL	POLM	POLN	POLQ	POLR2I	PPP4C	PPP5C	PRDM9	PRIMPOL	PRKDC	PRMT6	PRPF19	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD14	PSME4	PTTG1	PWWP3A	RAD1	RAD17	RAD18	RAD21	RAD21L1	RAD23A	RAD23B	RAD50	RAD51	RAD51AP1	RAD51B	RAD51C	RAD51D	RAD52	RAD54B	RAD54L	RAD9A	RAD9B	RBBP4	RBBP8	RBX1	REC8	RECQL	RECQL4	RECQL5	REV1	REV3L	REXO4	RFC1	RFC2	RFC3	RFC4	RFC5	RFWD3	RHNO1	RIF1	RMI1	RMI2	RNASEH2A	RNASEH2B	RNASEH2C	RNF111	RNF113A	RNF138	RNF168	RNF169	RNF8	RPA1	RPA2	RPA3	RPA4	RPS3	RRM1	RRM2	RRM2B	RTEL1	RUVBL1	RUVBL2	SAMHD1	SEM1	SETD2	SETMAR	SETX	SFPQ	SFR1	SHLD1	SHLD2	SHLD3	SHPRH	SIRT1	SIRT6	SIRT7	SIX6OS1	SLC30A9	SLF1	SLF2	SLX1A	SLX4	SMARCA5	SMARCAD1	SMARCAL1	SMC1A	SMC3	SMC5	SMC6	SMCHD1	SMG1	SMUG1	SPATA22	SPIDR	SPO11	SPRTN	SSRP1	STUB1	SUMO1	SUPT16H	SWI5	SWSAP1	SYCP1	TAOK1	TAOK3	TDG	TDP1	TDP2	TENT4A	TEX15	TEX264	TFPT	TICRR	TIMELESS	TNKS1BP1	TNP1	TONSL	TOP3A	TOP3B	TOPBP1	TP53	TP53BP1	TP73	TRAIP	TREX1	TREX2	TRIM28	TRIP12	TRIP13	TTC5	TTF2	UBE2A	UBE2B	UBE2D3	UBE2N	UBE2T	UBE2U	UBE2V2	UBE2W	UBQLN4	UBR5	UCHL5	UFL1	UHRF1	UIMC1	UNG	UPF1	USP1	USP10	USP28	USP3	USP44	USP45	USP47	USP51	USP7	USP9X	UVRAG	UVSSA	VCP	VCPIP1	WDHD1	WDR48	WHR1	WRAP53	WRN	WRNIP1	XAB2	XNDC1N	XPA	XPC	XRCC1	XRCC2	XRCC3	XRCC4	XRCC5	XRCC6	YY1	ZBTB1	ZBTB7A	ZFYVE26	ZGRF1	ZMYND8	ZNF668	ZRANB3	ZSWIM7
KE239_Activation_Pregnane_X_receptor_NR1l2_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE715_Activation_Constitutive_androstane_receptor_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE245_Activation_PXR_SXR_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE55_Increase_Cell_injury_death_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE757_Hippocampal_anatomy_Altered_GO:0021766	hippocampus development	ATP2B4	BBS2	BBS4	CASP3	CDK6	CFL1	EIF2B5	EPHA5	EZH1	EZH2	FEZ1	FGF13	FXR1	FXR2	GSK3B	HTR5A	KCNA1	KDM6B	KIF14	KIRREL3	LRP8	MDK	MFSD2A	MKKS	NCOA1	NEFL	NEUROD1	OGDH	PAFAH1B1	PHLPP2	PLXNA3	PPP1R9B	PROX1	PTEN	RAN	RARA	RELN	SCT	SEMA6B	SLC32A1	SRD5A1	SRD5A2	TMEM108	TSKU	TUBA1A	UQCRQ	XRN2	ZIC1	ZIC3
KE758_Hippocampal_Physiology_Altered_GO:0007268	chemical synaptic transmission	ACHE	ACP1	ADORA1	ADORA2A	AGRN	AKAP5	AKAP9	AKT1	AMPH	ANXA9	AP2B1	APBA1	APBA2	APBA3	APOE	ARRB2	ATXN3	BEGAIN	BEST1	BRSK1	BSN	CACNA1A	CACNA1B	CACNA1E	CACNB1	CACNB2	CACNB3	CACNB4	CADPS	CADPS2	CARTPT	CBLN1	CBLN2	CDK5	CEP89	CHAT	CHRDL1	CHRFAM7A	CHRM1	CHRM2	CHRM3	CHRM4	CHRM5	CHRNA1	CHRNA10	CHRNA2	CHRNA3	CHRNA4	CHRNA5	CHRNA6	CHRNA7	CHRNA9	CHRNB1	CHRNB2	CHRNB3	CHRNB4	CHRND	CHRNE	CHRNG	CNIH2	CNIH3	CNP	COLQ	CORT	CPLX1	CPLX2	CPLX3	CPLX4	CRH	CRHBP	DBH	DLG1	DLG2	DLG3	DLG4	DLGAP1	DLGAP2	DNAJC5	DOC2A	DOC2B	DRD1	DRD2	DRD3	DRD4	DRD5	DTNA	DVL1	EEA1	EFR3A	ELFN1	ELFN2	ERC2	EXOC4	EZH2	FCHSD1	FCHSD2	GABARAP	GABBR1	GABBR2	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB1	GABRB2	GABRB3	GABRD	GABRE	GABRG1	GABRG2	GABRG3	GABRP	GABRQ	GABRR1	GABRR2	GABRR3	GAD1	GAD2	GALR3	GIPC1	GLRA1	GLRA2	GLRA3	GLRB	GPR176	GRIA1	GRIA2	GRIA3	GRIA4	GRID1	GRID2	GRIK1	GRIK2	GRIK3	GRIK4	GRIK5	GRIN1	GRIN2A	GRIN2B	GRIN2C	GRIN2D	GRIN3A	GRIN3B	GRM1	GRM2	GRM3	GRM4	GRM5	GRM6	GRM7	GSK3A	GSK3B	HAP1	HAPLN4	HCRT	HCRTR1	HCRTR2	HOMER1	HRH1	HRH2	HRH3	HRH4	HTR1A	HTR1B	HTR1D	HTR1E	HTR1F	HTR2A	HTR2B	HTR2C	HTR3A	HTR3B	HTR3C	HTR3D	HTR3E	HTR4	HTR5A	HTR6	HTR7	INSYN1	INSYN2A	KCNC4	KCND2	KCND3	KCNIP1	KCNIP2	KCNK2	KCNK3	KCNMB1	KCNMB4	KCNN1	KCNQ2	KCNQ3	KIF1B	KIF5A	LIN7A	LIN7B	LIN7C	LPAR3	LRP6	LRP8	LRRK2	MAPK1	MBP	MEF2C	MET	MINK1	MPP2	MPZ	MTNR1B	MYCBPAP	NAPA	NAPB	NLGN1	NLGN3	NOTCH1	NPAS4	NPBWR1	NPFF	NPR2	NPTX1	NPTX2	NPY	NPY5R	NQO1	NR3C1	NRXN1	NRXN2	NSG1	NTSR1	OMP	OPRK1	OPRL1	OTOF	P2RX1	P2RX2	P2RX3	P2RX4	P2RX5	P2RX6	P2RX7	PAFAH1B1	PCDH8	PCDHB10	PCDHB11	PCDHB13	PCDHB14	PCDHB16	PCDHB2	PCDHB3	PCDHB4	PCDHB5	PCDHB6	PCDHB9	PCLO	PDE7B	PDLIM4	PDYN	PDZD11	PENK	PIP5K1C	PLP1	PMCH	PMCHL1	PMCHL2	PMP22	PNOC	PPFIA3	PRKAR1A	PRKAR1B	PRKAR2A	PRKAR2B	PRKCG	PRRT2	PTCHD1	PTEN	PTPRN2	PVALB	RAB3A	RAB3GAP1	RAPSN	RASD2	RIC3	RIMBP2	RIMS1	RIMS2	RIMS3	RIT2	RPH3A	RPH3AL	RPS6KA1	RPS6KA2	RPS6KA3	SCN2B	SCRIB	SDCBP	SEPTIN5	SHISA6	SLC12A4	SLC12A5	SLC12A6	SLC12A7	SLC17A6	SLC17A7	SLC17A8	SLC18A2	SLC18A3	SLC1A1	SLC1A2	SLC1A3	SLC1A4	SLC1A6	SLC1A7	SLC29A1	SLC32A1	SLC5A7	SLC6A1	SLC6A2	SLC6A3	SLC6A5	SNAP23	SNAP25	SNAP29	SNAP47	SNAPIN	SNCA	SNCB	SNCG	SNPH	SPG11	SSH1	SST	STAC3	STX11	STX19	STX1A	STX1B	STX2	STXBP1	STXBP2	STXBP3	SV2A	SV2B	SV2C	SYN1	SYN2	SYN3	SYNJ1	SYPL1	SYT1	SYT10	SYT11	SYT12	SYT13	SYT2	SYT3	SYT4	SYT5	SYT6	SYT7	SYT8	SYT9	TAC1	TH	TRPV1	UNC119	UNC13A	UNC13B	UNC13C	UTS2	VAMP1	VAMP2	VPS54
KE68_Accumulation_Collagen_GO:0032964	collagen biosynthetic process	ADAMTS3	COL1A1	COL5A1	P3H3	P3H4	PCOLCE	PLOD1	PLOD2	PLOD3	RCN3	TMEM131	TRAM2	TRAPPC8
KE68_Accumulation_Collagen_GO:0030574	collagen catabolic process	ADAM15	ADAMTS14	ADAMTS2	ADAMTS3	CTSB	CTSK	CTSL	CTSS	FURIN	KLK6	MMP1	MMP10	MMP11	MMP12	MMP13	MMP14	MMP15	MMP16	MMP17	MMP19	MMP2	MMP20	MMP21	MMP23B	MMP24	MMP25	MMP26	MMP27	MMP28	MMP3	MMP7	MMP8	MMP9	MRC2	PEPD	PLG	PRSS2	PRTN3	TMPRSS6
KE898_Disruption_Lysosome_GO:0007040	lysosome organization	ABCA1	ACP2	AKTIP	AP5B1	AP5M1	AP5S1	AP5Z1	ARL8B	ARSB	ATP10B	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4C	CHMP5	CHMP6	CHMP7	CLN3	CLN5	CLN6	CLVS1	CLVS2	CORO1A	CREG1	FHIP1B	GAA	GBA1	GNPTAB	GRN	HOOK1	HOOK2	HOOK3	HPS1	HPS4	LAMTOR1	LRRK2	LYSET	LYST	MBTPS1	MFSD8	MYO7A	NAGPA	OSBPL10	OSBPL11	OSBPL9	PI4KB	PIKFYVE	PLA2G5	RAB14	RAB20	RAB34	RAB39A	RAB7A	RAB7B	RUFY4	SNAPIN	SPG11	SRPX	SYT7	TFE3	TFEB	TMEM106B	TMEM175	TMEM63A	TPCN2	TPP1	VIPAS39	VPS18	VPS33B	VPS35	ZFYVE26	ZKSCAN3
KE1539_Endocytotic_lysosomal_uptake_GO:0006897	endocytosis	AAK1	ABCA7	ABL1	ACE2	ACKR3	ADGRB1	ADM	ADORA1	ADORA2A	ADRB2	AGER	AHSG	AIF1	ALOX15	AMN	AMPH	ANK2	ANKFY1	ANXA1	ANXA11	ANXA3	AP1S1	AP2A1	AP2A2	AP2B1	AP2M1	AP2S1	AP3B2	AP3D1	AP3M1	AP3M2	AP3S1	AP3S2	APLP1	APOE	APP	ARC	ARF6	ARHGAP12	ARHGAP25	ARHGAP27	ARHGEF37	ARL8B	ARR3	ARRB1	ARRB2	ASGR1	ASGR2	ATP6V1H	ATP8A1	ATP9A	ATP9B	AXL	BCL2L1	BECN1	BIN1	BIN2	BIN3	BLTP1	BTBD8	C9orf72	CALCRL	CALM1	CALM2	CALM3	CALY	CANX	CAPN2	CARMIL1	CAV1	CAV2	CAV3	CBL	CCDC158	CD14	CD209	CD302	CD36	CD44	CD81	CD9	CD93	CDC42	CDC42SE1	CDC42SE2	CDK5	CEACAM1	CEACAM4	CLCN2	CLEC10A	CLEC4F	CLEC4M	CLEC7A	CLEC9A	CLINT1	CLN3	CLTA	CLTB	CLTC	CLTCL1	COLEC12	CORO1A	CORO1C	CREG1	CRYBA1	CSNK1D	CSNK1E	CSNK1G1	CSNK1G2	CSNK1G3	CTBP1	CTSL	CTTN	CUBN	CXCL16	CXCL8	CXCR1	CXCR2	CYTH2	DAB2	DBNL	DENND1A	DENND1B	DENND1C	DGKD	DLL1	DNAJC13	DNAJC6	DNASE2	DNER	DNM1	DNM1L	DNM2	DNM3	DOCK1	DOCK2	DPP4	DPYSL2	DRD2	DRD3	EEA1	EHBP1	EHD1	EHD2	EHD3	EHD4	ELANE	ELMO1	ELMO2	ELMO3	ENTHD1	ENTREP1	EPN1	EPN2	EPN3	EPS15	EPS15L1	EQTN	ESYT2	FCER1G	FCER2	FCGR1A	FCGR2B	FCHO1	FCHO2	FCHSD2	FCMR	FCN1	FCN2	FCN3	FGR	FKBP15	FNBP1	FNBP1L	FOLR1	FPR2	FYN	GAK	GAPVD1	GAS6	GAS7	GATA2	GHR	GPR107	GRB2	GRIA1	GRK2	GRK3	GRK4	GSN	GTF2H2	GULP1	HAVCR1	HCK	HEATR5A	HEATR5B	HFE	HGS	HIP1	HIP1R	HMGB1	HMMR	HOOK2	HSPA8	HSPG2	ICAM3	ICAM4	IFNG	IGF2R	IL10RA	INPP5F	INPPL1	INSR	ITCH	ITGA4	ITGAL	ITGAM	ITGAV	ITGAX	ITGB1	ITGB2	ITGB3	ITSN1	ITSN2	JMJD6	KCNN4	LDLR	LDLRAD3	LDLRAP1	LEP	LEPR	LILRB1	LILRB4	LIMK1	LMBR1L	LMBRD1	LRP1	LRP10	LRP12	LRP1B	LRP2	LRP3	LRP4	LRP5	LRP6	LRP8	LRRK2	LRSAM1	LTAP1	LY75	LYN	LYST	LYVE1	M6PR	MAGI2	MAPK1	MAPK3	MAPKAPK2	MAPKAPK3	MARCHF2	MARCHF3	MARCO	MEGF10	MERTK	MESD	MFGE8	MIB1	MICALL1	MLC1	MRC1	MRC2	MSR1	MST1R	MTMR6	MTMR9	MX1	MX2	MYCBPAP	MYD88	MYH9	MYO15A	MYO19	MYO1A	MYO1B	MYO1C	MYO1D	MYO1E	MYO1F	MYO1G	MYO1H	MYO5A	MYO5B	MYO5C	MYO6	MYO7A	MYO7B	NCF2	NCF4	NCKIPSD	NECAP1	NECAP2	NEDD4	NEDD4L	NEURL1B	NEURL3	NLGN3	NME1	NOS2	NOSTRIN	NR1H3	OCIAD1	OCIAD2	OPHN1	P2RY6	PACSIN1	PACSIN2	PACSIN3	PAK1	PDLIM7	PECAM1	PI4KB	PICALM	PIK3C2A	PIK3C3	PIK3CA	PIK3CB	PIK3CG	PIKFYVE	PIP5K1A	PIP5K1C	PLA2G5	PLA2G6	PLA2R1	PLD2	PLD4	PLPP4	PLXNB2	PPT1	PRKCD	PRKCE	PSTPIP1	PTK2	PYCARD	RAB11FIP2	RAB14	RAB15	RAB1A	RAB20	RAB22A	RAB27B	RAB31	RAB34	RAB39A	RAB5A	RAB5B	RAB5C	RAB7A	RAB7B	RAB9A	RAB9B	RABEP1	RABEP2	RABEPK	RABGAP1L	RABGEF1	RAC1	RALA	RALB	RALBP1	RAMP1	RAMP2	RAMP3	RARA	REPS1	REPS2	RHOJ	RHOQ	RHOU	RHOV	RIN1	RIN2	RIN3	RINL	RNASEK	RUBCN	RUFY1	SAG	SCAMP1	SCARA5	SCARB1	SCARB2	SCARF1	SCRIB	SCYL2	SDC1	SFTPD	SGIP1	SH3BP1	SH3BP4	SH3GL1	SH3GL2	SH3GL3	SH3GLB1	SH3GLB2	SH3KBP1	SIGLEC1	SLAMF1	SLC11A1	SLC48A1	SLC9B2	SNAP91	SNCA	SNCB	SNCG	SNX1	SNX18	SNX33	SNX5	SNX9	SORL1	SORT1	SRC	SRPX	STAB1	STAB2	STEAP2	STON1	STON2	STX1A	SYK	SYNJ1	SYNJ2	SYNRG	SYP	SYT7	TAFA4	TBC1D2B	TFR2	TFRC	TGM2	THBS1	TICAM2	TIMD4	TLR4	TM9SF4	TMEM108	TMEM175	TNK2	TOM1	TPCN2	TREM2	TRIP10	TSC2	TUB	TULP1	TYRO3	TYROBP	UNC119	USP20	USP33	VAMP2	VAMP7	VAV1	VAV2	VAV3	VIPAS39	VLDLR	VPS33B	WASF1	XKR4	XKR6	XKR7	XKR8	YES1	ZFYVE9
KE961_Increased_Clearance_of_thyroxine_from_serum_GO:0042404	thyroid hormone catabolic process	DIO1	DIO2	DIO3
KE295_Induction_Upregulation_of_glucuronyltransferase_activity_GO:0006805	xenobiotic metabolic process	AADAC	ABCB1	ABCB11	ABCC1	ABCC2	ABCC3	ABCC4	ABCC5	ABHD10	ACAA1	ACSL1	ACSM1	ACSM2B	ADA	AHR	AHRR	AKR1C1	ALDH2	ALDH3A1	AOC2	AOX1	ARNT	ARNT2	AS3MT	BCHE	BPHL	CAD	CBR1	CBR3	CES2	CES3	CMBL	CRYZ	CYB5B	CYP1A1	CYP1A2	CYP1B1	CYP26A1	CYP26B1	CYP2A13	CYP2A6	CYP2A7	CYP2B6	CYP2C18	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP2D7	CYP2E1	CYP2F1	CYP2J2	CYP2R1	CYP2S1	CYP2U1	CYP2W1	CYP3A4	CYP3A5	CYP3A7	CYP46A1	CYP4F12	CYP4F2	DPYD	EPHX1	FMO2	FMO4	FMO5	GLYAT	GRIN1	GSTA1	GSTA2	GSTA3	GSTA4	GSTA5	GSTM1	GSTM2	GSTM3	GSTM4	GSTO1	GSTO2	GSTP1	GUK1	HEMK2	HNF4A	NAT1	NAT2	NOS1	NQO1	NR1I2	NUDT15	PRKCE	RBBP9	RORA	RORC	S100A12	SLC22A1	SLC22A7	SLC28A2	SLC28A3	SLC29A1	SLC29A3	SLCO1A2	SLCO1B1	SLCO1B3	SLCO2B1	SMOX	SULT1A1	SULT1A2	SULT1A3	SULT1B1	SULT1C3	SULT1C4	SULT2A1	TPMT	UGT1A1	UGT1A10	UGT1A3	UGT1A6	UGT1A7	UGT1A8	UGT1A9	UGT2A1	UGT2A2	UGT2A3	UGT2B11	UGT2B15	UGT2B17	UGT2B4	UGT2B7	UPP2	VKORC1
KE227_Activation_PPAR_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE1157_Activation_Hepatic_nuclear_receptor_s_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE1158_Increased_Hepatic_thyroid_hormone_uptake_transport_GO:0070327	thyroid hormone transport	CRYM	SERPINA7	SLC16A10	SLC16A2	SLC17A4	SLC3A2	SLC7A5	SLC7A8	SLCO1B1	SLCO1C1	SLCO4A1	TUBB1
KE1284_Up_Regulation_SREBF2_GO:0032933	SREBP signaling pathway	ARHGEF10L	ERLIN1	ERLIN2	INSIG1	INSIG2	SCAP	SREBF1	SREBF2
KE1285_Up_Regulation_Unsaturated_fatty_acid_GO:0006636	unsaturated fatty acid biosynthetic process	AKR1C3	ALOX12	ALOX15	ALOX15B	CBR1	CD74	CTHRC1	DAGLB	DECR2	DEGS1	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	FADS1	FADS2	FADS2B	FADS3	HPGDS	MIF	PLA2G10	PLA2G4A	PNPLA8	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGS1	PTGS2	SCD	SCD5	SIGMAR1	TBXAS1
KE1286_Down_Regulation_GSS_and_GSTs_gene_GO:0006749	glutathione metabolic process	CHAC1	CHAC2	CNDP2	CTNS	DPEP1	ETHE1	G6PD	GCLC	GCLM	GGT1	GGT2P	GGT3P	GGT5	GGT6	GGT7	GGTLC1	GGTLC2	GGTLC3	GLO1	GLRX2	GPX1	GSR	GSS	GSTA1	GSTA2	GSTA3	GSTA4	GSTA5	GSTK1	GSTM1	GSTM2	GSTM3	GSTM4	GSTM5	GSTO1	GSTO2	GSTP1	GSTT1	GSTT2	GSTT2B	GSTT4	GSTTP2	GSTZ1	HAGH	HPGDS	MGST2	MMACHC	NAT8	OPLAH	SLC1A1	SLC1A2	SNCA	SOD1
KE1288_Activation_3_hydroxy_3_methylglutaryl_CoA_reductase_gene_GO:0006695	cholesterol biosynthetic process	ACAA2	ACLY	ARV1	CES1	CYB5R3	CYP51A1	DHCR24	DHCR7	EBP	FDFT1	FDPS	G6PD	HMGCR	HMGCS1	HMGCS2	HSD17B7	IDI1	IDI2	INSIG1	INSIG2	LBR	LSS	MSMO1	MVD	MVK	NPC1L1	NSDHL	PLPP6	PMVK	PRKAA1	PRKAA2	SC5D	SQLE	TM7SF2
KE244_Alkylation_Protein_GO:0008213	protein alkylation	ANTKMT	ATPSCKMT	CAMKMT	CSKMT	EEF1AKMT1	EEF1AKMT2	EEF1AKMT3	EEF2KMT	EHMT1	EHMT2	ETF1	ETFBKMT	FAM98A	FAM98B	GSPT1	HEMK2	ICMT	KMT5A	LCMT1	METTL18	METTL21A	METTL21C	METTL22	NDUFAF7	NTMT1	NTMT2	PCMT1	PRDM12	PRMT1	PRMT3	PRMT5	PRMT7	PRMT8	RAB6A	SETD2	SETD3	SETD6	SETD7	SMYD2	SNRPB	SNRPD3	TRMT112	VCPKMT
KE87_Release_Cytokine_GO:0001816	cytokine production	ADAM17	ADAMTS3	CASP1	CHI3L1	CMA1	COL3A1	FOSL2	FURIN	HIF1A	IL13	IL13RA2	IL1B	IL6	IL6R	ITGAV	ITGB6	JUN	PCSK5	TMEM219	TNF
KE288_Activation_of_specific_nuclear_receptors_Transcriptional_change_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE887_Inhibition_NADH_ubiquinone_oxidoreductase_complex_I_GO:0006120	mitochondrial electron transport, NADH to ubiquinone	COXFA4	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	NDUFA1	NDUFA10	NDUFA11	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFAF1	NDUFB1	NDUFB10	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFC2-KCTD14	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3
KE888_Binding_of_inhibitor_NADH_ubiquinone_oxidoreductase_complex_I_GO:0006120	mitochondrial electron transport, NADH to ubiquinone	COXFA4	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	NDUFA1	NDUFA10	NDUFA11	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFAF1	NDUFB1	NDUFB10	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFC2-KCTD14	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3
KE111_Agonism_Estrogen_receptor_GO:0030520	estrogen receptor signaling pathway	AR	CCDC62	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	NCOA1	NCOA4	PADI2	POU4F2	PPARGC1B	RBFOX2	SAFB	TADA3	TRIP4
KE364_Impaired_development_of_Reproductive_organs_GO:0061458	reproductive system development	ACE	ADAM15	ADAM18	ADAM2	ADAM20	ADAM21	ADAM29	ADAM30	ADAM32	ADGRG1	AKR1C3	ALOX15B	AMH	AMHR2	ANG	AR	BASP1	BIK	BMPR1B	BOK	CASP2	CASP3	CBL	CCDC182	CCND1	CEBPB	CGA	CHD7	CRIP1	CSDE1	CTNNA1	CYP19A1	DCANP1	DMRT1	DNAAF11	DNAJC19	EIF2B2	EIF2B4	EIF2B5	EREG	FER	FGF8	FGF9	FGFR2	FLNA	FOXF2	FOXL2	FSHB	FSHR	GATA1	GATA3	GATA4	GATA6	GFRA1	GLI1	HOXA10	HOXA11	HOXA13	HOXA9	HOXB13	HOXD13	HSD17B3	HYAL3	IDH1	ING2	INHA	INHBA	INHBB	INSR	IRX5	KIT	KITLG	LEP	LHB	LHCGR	LHX1	LRP2	LSM14B	MAMLD1	MEA1	MKKS	MMP14	MMP19	MMP2	MSH2	NASP	NCOA1	NCOA4	NEUROG1	NIPBL	NKX3-1	NOTCH1	NPPC	NPR2	NR0B1	NR2F2	NR5A1	NR5A2	NRIP1	NTRK1	NUP107	PDGFRA	PKD1	PPP1R9B	PRKACG	PRPS1L1	PSAP	PSAPL1	PTCH1	PTPN11	PTPRN	RAB13	RARA	RBMY1B	RBP4	REN	ROBO2	SALL1	SCX	SHH	SIX4	SLIT2	SLIT3	SMAD4	SMARCC1	SOD1	SOX15	SOX8	SOX9	SRD5A1	SRD5A2	STRA6	TACR3	TBX3	TCF21	TESC	TEX19	TFAP2C	TGFB2	TIFAB	TLR9	TNFAIP6	TSPY1	TSPY10	TSPY2	TSPY3	TSPY4	TSPY8	TSPY9	UTF1	VEGFA	WNT2B	WNT4	WNT5A	WNT7A	WT1	ZFP42	ZFPM2	ZNF830
KE66_Activation_ChREBP_GO:0010255	glucose mediated signaling pathway	ADCY8	AGER	MLXIPL	NKX6-1	PDX1	USF1	USF2
KE89_Synthesis_De_Novo_Fatty_Acid_FA_GO:0006633	fatty acid biosynthetic process	ABCD1	ABCD2	ABCD3	ABHD1	ABHD2	ABHD3	ACACA	ACACB	ACLY	ACOT4	ACOT7	ACOT8	ACOX1	ACSBG1	ACSBG2	ACSF3	ACSL1	ACSL4	ACSM1	ACSM2A	ACSM2B	ACSM3	ACSM4	ACSM5	ACSM6	ACSS1	ACSS2	AKR1C3	ALOX12	ALOX12B	ALOX15	ALOX15B	ALOX5	ALOXE3	ASAH2	BRCA1	CBR1	CBR4	CD74	CTHRC1	CYP1A1	CYP1A2	CYP2C8	CYP2C9	CYP2D6	CYP2E1	CYP3A4	DAGLB	DECR2	DEGS1	EHHADH	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	FA2H	FADS1	FADS2	FADS2B	FADS3	FADS6	FASN	GPX4	GSTM1	GSTM2	GSTM4	GSTP1	HACD1	HACD2	HACD3	HACD4	HPGDS	HSD17B12	HSD17B4	HSD17B8	HTD2	LIAS	LIPC	LIPG	LPL	LTC4S	MCAT	MECR	MGLL	MIF	MLYCD	NDUFAB1	OLAH	OXSM	PECR	PLA2G10	PLA2G1B	PLA2G4A	PNLIP	PNLIPRP1	PNLIPRP2	PNLIPRP3	PNPLA8	PRKAA1	PRKAA2	PRKAB1	PRKAB2	PRKAG1	PRKAG2	PRKAG3	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGS1	PTGS2	SCD	SCD5	SCP2	SIGMAR1	TBXAS1	TECR	TECRL	TMEM135	XBP1
KE140_Decreased_HSD17B10_expression_GO:0006635	fatty acid beta-oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ADIPOQ	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HADH	HADHA	HADHB	HSD17B10	HSD17B4	IVD	MCAT	MTLN	PEX2	PPARD	SCP2	SLC25A17	SLC27A2
KE179_Decrease_Fatty_acid_beta_oxidation_GO:0006635	fatty acid beta-oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ADIPOQ	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HADH	HADHA	HADHB	HSD17B10	HSD17B4	IVD	MCAT	MTLN	PEX2	PPARD	SCP2	SLC25A17	SLC27A2
KE231_Decreased_PPAR_alpha_activation_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE232_Decreased_PPAR_beta_activation_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE462_Up_Regulation_SCD_1_GO:0006636	unsaturated fatty acid biosynthetic process	AKR1C3	ALOX12	ALOX15	ALOX15B	CBR1	CD74	CTHRC1	DAGLB	DECR2	DEGS1	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	FADS1	FADS2	FADS2B	FADS3	HPGDS	MIF	PLA2G10	PLA2G4A	PNPLA8	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGS1	PTGS2	SCD	SCD5	SIGMAR1	TBXAS1
KE472_Down_Regulation_CPT1A_GO:0006853	carnitine shuttle	CPT1A	CPT1B	CPT2	SLC25A20	THRSP
KE853_Changes_Inhibition_Cellular_Homeostasis_and_Apoptosis_GO:0019725	cellular homeostasis	ABCA12	ABCA2	ABCB6	ABCB7	ABCB8	ABCC6	ABCC8	ACO1	ACVR2B	ADCY8	ADNP	ADORA1	AFG3L2	AGER	AIM2	ALAS2	ALDOA	ANK2	ANKRD9	ANO6	ANXA6	APP	AQP1	AQP11	AQP4	ARF1	ARRB1	ASPH	ATOX1	ATP12A	ATP13A1	ATP13A2	ATP13A3	ATP13A4	ATP13A5	ATP1A1	ATP1A2	ATP1A3	ATP1A4	ATP1B1	ATP1B2	ATP1B3	ATP2A1	ATP2A2	ATP2A3	ATP2B1	ATP2B2	ATP2B3	ATP2B4	ATP2C1	ATP2C2	ATP4A	ATP4B	ATP5F1B	ATP6AP1	ATP6AP2	ATP6V0A1	ATP6V0A2	ATP6V0A4	ATP6V0B	ATP6V0C	ATP6V0D1	ATP6V0D2	ATP6V0E1	ATP6V0E2	ATP6V1A	ATP6V1B1	ATP6V1B2	ATP6V1C1	ATP6V1D	ATP6V1E1	ATP6V1F	ATP6V1G1	ATP6V1G2	ATP6V1G3	ATP6V1H	ATP7A	ATP7B	AVP	AVPR1A	B2M	BAG3	BAK1	BAX	BCL2	BMP2	BMP6	BNIP3	BOK	BOLA1	BOLA2	BOLA3	C19orf12	C1QTNF3	CA2	CA7	CACNB2	CACNB4	CALB1	CALB2	CALCA	CALCB	CALR	CAMK2D	CAPN3	CARTPT	CASQ2	CASR	CAV1	CAV2	CAV3	CCDC22	CCDC47	CCDC51	CCL1	CCL11	CCL13	CCL14	CCL15	CCL19	CCL2	CCL23	CCL3	CCL5	CCL7	CCL8	CCR1	CCR2	CD40	CDH23	CDH5	CFTR	CHD6	CHERP	CHMP2B	CHP1	CHP2	CHRNA1	CHRNA7	CIAO3	CISD1	CLCC1	CLCN3	CLCN6	CLDN16	CLN3	CLN5	CLN6	CLNS1A	CLTRN	CMA1	CNGB1	CNNM4	CNR1	COL1A1	COX11	COX19	CP	CREG1	CSRP3	CTRC	CUL1	CX3CL1	CXCL12	CYB561	CYB561A3	CYBA	CYBRD1	CYP7A1	DCTN1	DDIT3	DEDD2	DGAT2	DHRS7C	DMD	DMPK	DMTN	DMXL1	DMXL2	DNAJB2	DRD3	DRD4	DRD5	EDN1	EDN2	EDN3	EDNRA	EGLN1	EGLN2	ELANE	ENDOG	ENPP1	EPAS1	ERC2	ERFE	ERN1	ERO1A	ERP44	F2	FASLG	FATE1	FBXL5	FBXW7	FGGY	FIS1	FITM2	FLVCR1	FOXA3	FOXK1	FOXK2	FOXO1	FOXO3	FRRS1	FTH1	FTH1P19	FTHL17	FTL	FTMT	FUNDC2	FXN	FXYD1	FXYD3	FXYD4	FXYD5	FXYD6	FXYD7	FZD9	GAS6	GATA4	GCK	GCKR	GCLC	GCLM	GCM2	GDF2	GHRHR	GIT1	GLCCI1	GLRX2	GLRX3	GLRX5	GLS	GLUL	GNB3	GPER1	GPR89A	GPR89B	GPRC5B	GPX1	GRID2IP	GRM1	GRM5	GRN	GSR	GSTP1	HAAO	HAMP	HCRTR1	HCRTR2	HEPHL1	HERPUD1	HFE	HIF1A	HIF3A	HJV	HK1	HK2	HK3	HKDC1	HMOX1	HPX	HRC	HTR2A	HTR2B	HTR2C	HVCN1	IDE	IFNB1	IGF1R	IL2RG	IL6	IL7R	IREB2	IRS2	ISCU	ITPR1	KAT5	KCNB1	KCNE3	KCNH1	KCNJ2	KCNK16	KCNMA1	KCNQ1	KCTD17	KCTD7	KRIT1	LACC1	LAMP1	LAMP2	LARGE1	LARGE2	LDAH	LETM1	LIN28A	LRRC8A	LRRC8D	LRRC8E	LRRK2	MAIP1	MAP1A	MCL1	MCOLN1	MCU	MCUB	MCUR1	MECR	MICU1	MICU2	MICU3	MINPP1	MLXIPL	MRGPRE	MSTN	MT-RNR2	MT1A	MT1B	MT1DP	MT1E	MT1F	MT1G	MT1H	MT1HL1	MT1L	MT1M	MT1X	MT2A	MT3	MT4	MTM1	MUC17	MYC	MYH7B	NCF1	NCOA4	NDFIP1	NELL2	NFE2L2	NGFR	NKX6-1	NNT	NOS1	NOS2	NOS3	NPPA	NPPC	NPTN	NPTX1	NPY	NQO1	NR1D1	NR1H4	NUBP1	NUCKS1	NXNL1	OCA2	OGT	OPRK1	ORMDL1	ORMDL2	ORMDL3	OSBPL2	OXSR1	P2RX1	P2RX7	P2RY1	P2RY2	PACS2	PAX2	PCK1	PCK2	PDX1	PDZD8	PFKM	PICALM	PIK3R1	PIK3R2	PKHD1	PLAA	PLN	PML	PNPLA2	PPARGC1A	PPT1	PRDX1	PRDX2	PRDX3	PRDX4	PRDX5	PRDX6	PRKAA1	PRKAA2	PRKACA	PRKN	PRNP	PSEN1	PTH	PTH1R	PTPRN	PTPRN2	RAB11B	RAB11FIP2	RAB11FIP5	RAB20	RAB38	RAB39A	RAB7A	RACK1	RAP1GDS1	RBX1	RGN	RHAG	RHCG	RHOT1	RHOT2	RMDN3	RNASEK	RNF135	ROGDI	RPTOR	RTN4	RYR1	RYR2	RYR3	SCARA5	SCNN1A	SCNN1B	SCNN1D	SCNN1G	SCO1	SCO2	SCT	SCTR	SELENOK	SELENOS	SELENOT	SEPHS1	SERPINF1	SGCZ	SHANK3	SIRT1	SKP1	SLAMF8	SLC10A7	SLC11A1	SLC11A2	SLC12A1	SLC12A2	SLC12A3	SLC12A4	SLC12A5	SLC12A6	SLC12A7	SLC12A8	SLC12A9	SLC1A1	SLC22A12	SLC22A17	SLC24A1	SLC24A2	SLC24A3	SLC24A4	SLC24A5	SLC25A23	SLC25A27	SLC26A3	SLC26A6	SLC29A1	SLC2A10	SLC30A1	SLC30A10	SLC30A2	SLC30A5	SLC30A7	SLC30A8	SLC30A9	SLC34A1	SLC34A2	SLC34A3	SLC35G1	SLC38A3	SLC39A10	SLC39A12	SLC39A13	SLC39A14	SLC39A4	SLC39A5	SLC39A6	SLC39A7	SLC39A8	SLC39A9	SLC40A1	SLC41A1	SLC45A2	SLC46A1	SLC4A1	SLC4A10	SLC4A11	SLC4A2	SLC4A3	SLC4A4	SLC4A5	SLC4A7	SLC4A8	SLC4A9	SLC66A1	SLC6A2	SLC7A11	SLC8A1	SLC8A2	SLC8A3	SLC8B1	SLC9A1	SLC9A2	SLC9A3	SLC9A4	SLC9A5	SLC9A6	SLC9A7	SLC9A8	SLC9A9	SLC9B1	SLC9C1	SLC9C2	SMAD1	SMAD3	SMAD4	SMAD5	SMAD9	SMDT1	SOD1	SOD2	SOX4	SPPL2C	SRF	STC1	STC2	STIM1	STIM2	STK39	STOML2	SV2B	TAOK1	TASL	TBXAS1	TCIRG1	TESC	TESMIN	TF	TFR2	TFRC	TGFB1	TGM2	THADA	TM9SF4	TMC6	TMC8	TMCO1	TMEM163	TMEM165	TMEM175	TMEM178A	TMEM203	TMEM64	TMEM87A	TMEM9	TMEM94	TMPRSS3	TMPRSS6	TNNI3	TPCN2	TPP2	TPT1	TRA2B	TRDN	TREM2	TRIM32	TRIM6	TRPA1	TRPC1	TRPC3	TRPC4	TRPC5	TRPC6	TRPC7	TRPM7	TRPV4	TSC22D4	TSPOAP1	TUNAR	TXN	TXN2	TXNDC2	TXNRD1	TXNRD2	TXNRD3	TYRO3	UBE2C	UBE2K	UBE2S	UBE3A	UCP2	UNC13B	USF1	USF2	VAPB	VMA12	VMA21	VMA22	VPS33A	VPS54	WDR7	WFS1	WNK1	WNK3	WNK4	WNT5A	WNT7B	XBP1	XPR1	YWHAE	ZBTB20	ZNF236
KE853_Changes_Inhibition_Cellular_Homeostasis_and_Apoptosis_GO:0006915	apoptotic process	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CEACAM5	CEACAM6	CEBPB	CECR2	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FNIP2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA2	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLLN	KMT2A	KREMEN1	KRT20	LALBA	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NISCH	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NUAK2	NUDT2	OGT	OPA1	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNW1	SOD2	SORT1	SPI1	SPIN2B	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE854_Alterations_Cellular_proliferation_hyperplasia_GO:0008283	cell population proliferation	ABCB1	ABL1	ACE	ACVR1C	ACVRL1	AKNA	AKT1	ALKBH3	ANG	ANKRD45	AREG	ARHGEF2	ARIH2	ARTN	ATAD5	ATF2	ATF5	ATOH8	BAD	BAP1	BCL2	BGLAP	BMP10	BMP2	BMP4	BMP7	BMPER	BMPR2	BOP1	BRAT1	BTBD10	BTK	BTN3A1	C6orf89	CCN3	CD180	CD19	CD209	CD34	CD40	CD40LG	CD70	CD79A	CDC25A	CDC25C	CDH13	CDK3	CDK5RAP3	CDK9	CEACAM1	CEBPA	CEBPB	CEMP1	CEP120	CER1	CITED2	CLDN18	CLEC12B	CLU	CNTNAP2	COL3A1	CR2	CRK	CSF1	CSF1R	CTPS1	CUL4A	CUL4B	CX3CL1	DBN1	DCAF4	DCT	DDB1	DDIT3	DDR2	DDX41	DIO3	DIPK2A	DISC1	DIXDC1	DLG1	DLX3	DLX5	DMRT1	DOCK7	DOCK8	DSG2	DUX4L9	EBI3	EDNRA	EEF2	EGR1	ELAVL1	ELF4	EML1	EMP2	ENPEP	EPHA2	EPHB1	ERBB2	EREG	ERN1	ETV6	F2RL1	FABP4	FABP7	FAM83A	FAM83B	FAM83D	FAP	FBXW8	FERMT1	FES	FGF10	FGF13	FGF2	FGF4	FGF7	FGFR1	FGFR2	FGFR3	FGL1	FIGNL1	FLT3	FOS	FOXC1	GAPT	GLUL	GPC3	GSTP1	HEATR1	HELLS	HMGA2	HMGB1	HMOX1	HOOK3	HSPD1	ICAM3	ID2	IFNB1	IGF1	IGFBP5	IL10	IL17A	IL33	IL34	IL6	IRF2	ITGB1BP1	JUND	KANK1	KCNA1	KIF14	KIT	KLK8	KRAS	KRT2	LARP1	LIG4	LILRB1	LMBR1L	LOXL2	LTK	LYN	MAP4K1	MECOM	MEF2C	MEGF10	MELK	MIOS	MKI67	MMP14	MRPS27	MS4A1	MSN	MSX1	MT-RNR1	MTSS1	MUS81	MUSTN1	MVP	MYB	MYC	NAA35	NAA60	NDRG4	NDUFS2	NELFB	NES	NF2	NFIB	NFKBIZ	NKX3-1	NKX6-1	NMB	NOG	NOTCH1	NOX5	NPPC	NPR2	NPR3	NR4A3	NRARP	NUMB	NUMBL	OGFOD1	OR51E2	OSR1	OSR2	OTUD6B	PAFAH1B1	PAK5	PCM1	PCYT1A	PDGFRB	PDK1	PDS5B	PENK	PES1	PIK3CG	PLXNB2	POC1B	POLDIP2	POLR3G	PPARD	PPP3CB	PRDX1	PRKX	PROK1	PROK2	PTPRC	RAB10	RACGAP1	RASGRP1	RBX1	RETNLB	RHBDF1	RNF43	ROR1	RORA	RPS6KA1	RUNX1	RUNX2	SCRIB	SDCBP2	SDR16C5	SEMA5A	SERPINB1	SETMAR	SFRP2	SHH	SIX2	SIX3	SKI	SLAMF1	SLC11A1	SLC20A1	SLC26A2	SLC2A4	SLC39A5	SOX11	SOX4	SOX5	SOX9	SQSTM1	STAT1	STC1	TBCK	TBX1	TBX2	TEAD3	TEK	TGFA	TGFB2	TGFBI	TGFBR1	TGFBR3	THAP1	THPO	TMEM14B	TNFRSF14	TNFRSF4	TNFSF14	TNFSF18	TREM2	TRIM3	TRIM71	TRNP1	TWIST1	TYK2	UBE2L3	USP13	USP28	USPL1	VAV1	WNT1	WNT10B	WNT16	WNT2	WNT2B	WNT3	WNT3A	WNT5A	WNT7A	WNT7B	XBP1	YAP1	YJEFN3	YME1L1	YPEL5	YTHDF2	YY1AP1	ZEB2	ZNF324	ZNF416	ZNF503	ZNRF3	ZPR1
KE491_Clonal_Expansion_Cell_Proliferation_to_form_Altered_Hepatic_Foci_AHF_GO:0072574	hepatocyte proliferation	CEBPB	FGL1	IL6	RPS6KA1	TGFA
KE467_Increased_LDL_uptake_GO:0034383	low-density lipoprotein particle clearance	ADIPOQ	APOB	CD36	CES3	DGAT2	EHD1	HMOX1	LDLR	LDLRAP1	LIPA	NCEH1	SCARB1	SOAT1	SOAT2
KE2199_Increased_Expression_of_LXR_activated_genes_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE216_Decreased_PCK1_expression_control_point_for_glycolysis_gluconeogenesis_pathway_GO:0006094	gluconeogenesis	ALDOB	ALDOC	ATF4	CRTC2	CRY1	ENO1	ENO2	ENO3	FBP1	FBP2	G6PC1	G6PC2	G6PC3	GOT1	GPI	MDH2	PC	PCK1	PCK2	PER2	PFKFB1	PFKFB2	PFKFB3	PFKFB4	PGAM1	PGAM2	PGK1	PGK2	PGM1	PPARGC1A	RBP4	SDS	SLC25A10	SLC25A11	SLC25A13	SLC37A4	SLC39A14	TPI1
KE450_Suppression_VLDL_secretion_GO:0034379	very-low-density lipoprotein particle assembly	ACSL3	APOB	APOC1	APOC3	CIDEB	DGAT1	LPCAT3	MFSD2A	MTTP	SOAT1	SOAT2
KE451_Inhibition_Mitochondrial_fatty_acid_beta_oxidation_GO:0006635	fatty acid beta-oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ADIPOQ	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HADH	HADHA	HADHB	HSD17B10	HSD17B4	IVD	MCAT	MTLN	PEX2	PPARD	SCP2	SLC25A17	SLC27A2
KE465_Increased_FA_Influx_GO:0015908	fatty acid transport	ABCC4	ABCD1	ABCD2	ABCD3	ABCD4	ACE	ACSL1	ACSL3	APOE	BDKRB2	CD36	CPT1A	CPT1B	CPT2	CRABP1	CRABP2	DRD2	DRD3	DRD4	FABP1	FABP12	FABP2	FABP3	FABP4	FABP5	FABP5P3	FABP6	FABP7	FABP9	GOT2	LEP	LYN	LYPLA1	MFSD2A	NMB	NMUR2	NOS2	OC90	PLA2G10	PLA2G12A	PLA2G12B	PLA2G1B	PLA2G2A	PLA2G2C	PLA2G2D	PLA2G2E	PLA2G2F	PLA2G3	PLA2G4A	PLA2G5	PMP2	PNPLA8	PPARD	PPARG	PROCA1	RBP1	RBP2	RBP5	RBP7	RPS6KB1	SLC22A1	SLC22A11	SLC22A2	SLC22A6	SLC22A7	SLC22A8	SLC22A9	SLC25A17	SLC25A20	SLC27A1	SLC27A2	SLC27A3	SLC27A4	SLC27A5	SLC27A6	SLC2A1	SLC43A3	SLC5A8	SLCO1B1	SLCO2A1	SLCO2B1	SLCO3A1	SLCO4A1	SPX	THRSP	UCP2
KE466_Up_Regulation_LDLR_low_density_lipoprotein_receptor_GO:0034383	low-density lipoprotein particle clearance	ADIPOQ	APOB	CD36	CES3	DGAT2	EHD1	HMOX1	LDLR	LDLRAP1	LIPA	NCEH1	SCARB1	SOAT1	SOAT2
KE454_Increased_Triglyceride_formation_GO:0019432	triglyceride biosynthetic process	ACSL1	AGMO	AGPAT2	DGAT1	DGAT2	GK	GPAM	GPAT2	GPAT3	GPAT4	LPGAT1	LPIN1	LPIN2	LPIN3	MOGAT1	MOGAT2	MOGAT3	PNPLA3	TMEM68
KE456_Suppression_Constitutive_androstane_receptor_NR1l3_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE457_Activation_SREBF1_GO:0032933	SREBP signaling pathway	ARHGEF10L	ERLIN1	ERLIN2	INSIG1	INSIG2	SCAP	SREBF1	SREBF2
KE458_Increased_De_Novo_FA_synthesis_GO:0006633	fatty acid biosynthetic process	ABCD1	ABCD2	ABCD3	ABHD1	ABHD2	ABHD3	ACACA	ACACB	ACLY	ACOT4	ACOT7	ACOT8	ACOX1	ACSBG1	ACSBG2	ACSF3	ACSL1	ACSL4	ACSM1	ACSM2A	ACSM2B	ACSM3	ACSM4	ACSM5	ACSM6	ACSS1	ACSS2	AKR1C3	ALOX12	ALOX12B	ALOX15	ALOX15B	ALOX5	ALOXE3	ASAH2	BRCA1	CBR1	CBR4	CD74	CTHRC1	CYP1A1	CYP1A2	CYP2C8	CYP2C9	CYP2D6	CYP2E1	CYP3A4	DAGLB	DECR2	DEGS1	EHHADH	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	FA2H	FADS1	FADS2	FADS2B	FADS3	FADS6	FASN	GPX4	GSTM1	GSTM2	GSTM4	GSTP1	HACD1	HACD2	HACD3	HACD4	HPGDS	HSD17B12	HSD17B4	HSD17B8	HTD2	LIAS	LIPC	LIPG	LPL	LTC4S	MCAT	MECR	MGLL	MIF	MLYCD	NDUFAB1	OLAH	OXSM	PECR	PLA2G10	PLA2G1B	PLA2G4A	PNLIP	PNLIPRP1	PNLIPRP2	PNLIPRP3	PNPLA8	PRKAA1	PRKAA2	PRKAB1	PRKAB2	PRKAG1	PRKAG2	PRKAG3	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGS1	PTGS2	SCD	SCD5	SCP2	SIGMAR1	TBXAS1	TECR	TECRL	TMEM135	XBP1
KE463_Up_Regulation_FAS_GO:0006633	fatty acid biosynthetic process	ABCD1	ABCD2	ABCD3	ABHD1	ABHD2	ABHD3	ACACA	ACACB	ACLY	ACOT4	ACOT7	ACOT8	ACOX1	ACSBG1	ACSBG2	ACSF3	ACSL1	ACSL4	ACSM1	ACSM2A	ACSM2B	ACSM3	ACSM4	ACSM5	ACSM6	ACSS1	ACSS2	AKR1C3	ALOX12	ALOX12B	ALOX15	ALOX15B	ALOX5	ALOXE3	ASAH2	BRCA1	CBR1	CBR4	CD74	CTHRC1	CYP1A1	CYP1A2	CYP2C8	CYP2C9	CYP2D6	CYP2E1	CYP3A4	DAGLB	DECR2	DEGS1	EHHADH	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	FA2H	FADS1	FADS2	FADS2B	FADS3	FADS6	FASN	GPX4	GSTM1	GSTM2	GSTM4	GSTP1	HACD1	HACD2	HACD3	HACD4	HPGDS	HSD17B12	HSD17B4	HSD17B8	HTD2	LIAS	LIPC	LIPG	LPL	LTC4S	MCAT	MECR	MGLL	MIF	MLYCD	NDUFAB1	OLAH	OXSM	PECR	PLA2G10	PLA2G1B	PLA2G4A	PNLIP	PNLIPRP1	PNLIPRP2	PNLIPRP3	PNPLA8	PRKAA1	PRKAA2	PRKAB1	PRKAB2	PRKAG1	PRKAG2	PRKAG3	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGS1	PTGS2	SCD	SCD5	SCP2	SIGMAR1	TBXAS1	TECR	TECRL	TMEM135	XBP1
KE468_Inhibition_PPAR_alpha_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE470_Up_Regulation_Acetyl_CoA_carboxylase_1_ACC_1_GO:2001295	malonyl-CoA biosynthetic process	ACACA	ACACB
KE474_Down_Regulation_HMGCS2_GO:0046951	ketone body biosynthetic process	AACS	ACSS3	HMGCL	HMGCLL1	HMGCS2
KE478_Activation_NRF2_GO:0034599	cellular response to oxidative stress	ABCC1	ABL1	ABL2	ADPRS	AGAP3	AIF1	AIFM1	ALB	ALDH3B1	ANKZF1	APOA4	AQP1	ARNT	ATF2	ATF4	ATM	ATP13A2	ATP7A	BECN1	BMAL1	BNIP3	BRF2	BTK	CAMKK2	CAT	CBX8	CCS	CD36	CDK1	CFL1	CHCHD2	CIAPIN1	CRYGD	CUL1	CUL3	CYGB	CYP1B1	DAPK1	DHRS2	ECT2	EDN1	EDNRA	EIF2S1	ENDOG	ERCC6L2	ERMP1	ERN1	ETV5	FABP1	FANCC	FBXO31	FER	FOS	FOXO1	FOXO3	FXN	FYN	G6PD	GPR37	GPR37L1	GPX1	GPX2	GPX3	GPX4	GPX5	GPX6	GPX7	GPX8	GSR	HDAC2	HDAC6	HIF1A	HM13	HSPA1A	HSPA1B	HTRA2	IL18BP	IL18RAP	IL6	KAT2B	KEAP1	KLF2	KLF4	LCN2	LONP1	LRRK2	MAP1LC3A	MAP2K4	MAP3K5	MAPK13	MAPK7	MAPK8	MAPK9	MAPT	MB	MDM2	MGAT3	MGST1	MMP3	MSRA	MT3	MYB	NDOR1	NET1	NFE2L2	NOS3	NPPA	NQO1	NUDT2	OGG1	OSER1	PAM	PARK7	PARP1	PCNA	PDCD10	PDGFD	PDGFRA	PDK2	PENK	PEX10	PEX12	PEX13	PEX14	PEX2	PEX5	PINK1	PJVK	PKD2	PLA2R1	PLEKHA1	PNPT1	PPARGC1A	PPEF2	PPIA	PPIF	PPP5C	PRDX1	PRDX2	PRDX3	PRDX5	PRKAA1	PRKAA2	PRKCD	PRKD1	PRKN	PRR5L	PTPRK	PXN	PYCR1	PYCR2	PYROXD1	RAD52	RBM11	RBX1	RELA	RHOB	RIPK1	RIPK3	ROMO1	RPS3	SELENOS	SESN2	SETX	SIN3A	SIRPA	SIRT1	SIRT2	SLC25A24	SLC4A11	SNCA	SOD1	SOD2	SOD3	SRC	SRXN1	STAU1	STAU2	STK24	STK25	STK26	STX2	STX4	SUMO4	TBC1D24	TET1	TMEM161A	TNFAIP3	TOP2B	TP53	TPM1	TRPA1	TRPM2	TXN	UCP1	VKORC1L1	VRK2	WNT16	ZC3H12A	ZNF580
KE479_Activation_NR1H4_GO:0038185	nuclear receptor-mediated bile acid signaling pathway	NR1H4	VDR
KE480_Activation_SHP_GO:0141193	nuclear receptor-mediated signaling pathway	ABHD2	ACTN4	ALOXE3	AR	CALCOCO1	CALR	CCDC62	CST11	CYP24A1	DAXX	DDX17	DDX5	DDX54	DEFA1	DEFA3	EGLN2	ESR1	ESR2	ESRRA	ESRRB	ESRRG	FAM120B	GPER1	HDAC2	JAK2	KDM3A	KDM4C	MED1	NCOA1	NCOA2	NCOA3	NCOA4	NEDD4	NKX3-1	NR1D1	NR1H2	NR1H4	NR2C1	NR2E1	NR2E3	NR3C1	NR3C2	NR4A3	OR51E2	PADI2	PAQR7	PAQR8	PARK7	PDE3A	PDK3	PGR	PGRMC2	PHB1	PIM1	PLA2G10	PLPP1	PMEPA1	POU4F2	PPARA	PPARD	PPARG	PPARGC1B	PTF1A	RARA	RARB	RARG	RBFOX2	RHOXF1	RNF14	RWDD1	RXRA	RXRB	RXRG	SAFB	SCGB2A1	SCGB2A2	SNW1	SRC	TADA3	TBX1	THRA	THRB	TMF1	TRERF1	TRIP4	UBE3A	UBR5	VDR	WBP2	YWHAH	ZDHHC7	ZMIZ1
KE482_Decreased_DHB4_HSD17B4_GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	ACAA1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	AMACR	CRAT	CROT	DECR2	EHHADH	HSD17B4	SCP2	SLC27A2
KE484_Activation_AKT2_GO:0043491	phosphatidylinositol 3-kinase/protein kinase B signal transduction	ADAM17	AKT1	ATG14	C1QBP	C1orf54	CD160	EDN1	EGFR	ERBB2	ERBB3	FCGR3A	GAB2	GATA3	IGF1R	IRS1	LRP2	MKRN2	MTOR	MYO16	NF1	NYAP1	NYAP2	PDK1	PDPK1	PEAR1	PIK3C2A	PIK3C2B	PIK3C2G	PIK3C3	PIK3CA	PIK3CB	PIK3CD	PIK3CG	PIK3R1	PIK3R2	PIK3R3	PIK3R4	PIK3R5	PLEKHA1	PTEN	RGCC	SRPK2	STAT3	TYRO3	ZFP36L1
KE486_systemic_inflammation_leading_to_hepatic_steatosis_GO:0006954	inflammatory response	ABCF1	ABHD8	ACER3	ACKR1	ACKR2	ACOD1	ACVR1	ADAM17	ADAM8	ADCY1	ADCY8	ADGRE2	ADGRE5	ADM	ADORA1	ADORA2A	ADORA3	AFAP1L2	AGER	AGR2	AGTR1	AGTR2	AHSG	AIF1	AIM2	AIMP1	ALOX15	ALOX5	ANO6	ANXA1	AOC3	APCS	APIP	APOL2	APOL3	APP	ASS1	ATRN	AZU1	BCL6	BDKRB1	BDKRB2	BIRC2	BIRC3	BLNK	BMP2	BMP6	BMPR1B	BTK	C15orf39	C1QA	C2CD4A	C2CD4B	C3	C3AR1	C4A	C4B	C5	C5AR1	C5AR2	CAMK1D	CAMK4	CAMP	CARD18	CARD8	CASP1	CASP3	CASP4	CASP6	CASP8	CCL1	CCL11	CCL13	CCL14	CCL15	CCL16	CCL17	CCL18	CCL19	CCL2	CCL20	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL3L1	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCRL2	CD14	CD163	CD180	CD36	CD40	CD40LG	CD44	CD47	CD5L	CD6	CD68	CDO1	CEBPB	CELA1	CERS6	CFH	CHI3L1	CHIA	CHST1	CHST2	CHST4	CHUK	CLEC7A	CLU	CMKLR1	CNR2	CNTF	CRH	CRHBP	CRP	CSF1	CSF1R	CTNNBIP1	CUL3	CX3CL1	CX3CR1	CXCL1	CXCL10	CXCL11	CXCL13	CXCL2	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR2	CXCR3	CXCR4	CXCR6	CYBA	CYBB	DAB2IP	DHX9	DPEP1	DPP9	ELANE	ELF3	EPO	F11R	F12	F2	F2R	F2RL1	F3	F8	FADS2	FCER1A	FCER1G	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FFAR2	FFAR3	FFAR4	FN1	FOLR2	FOS	FPR1	FPR2	FPR3	FUT4	FUT7	GATA3	GBP5	GGT5	GPER1	GPR32	GPR32P1	GPR33	GPR68	GRN	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GZMA	GZMB	GZMK	HAVCR2	HBA1	HBB	HCK	HDAC4	HDAC5	HDAC9	HIF1A	HK1	HLA-DRB1	HMGB1	HMGB2	HMOX1	HNRNPA0	HP	HRH1	HRH4	HSPG2	HYAL1	HYAL3	IFI16	IFI27	IFNA2	IFNG	IFNGR1	IFNGR2	IGHE	IGHG1	IKBKB	IKBKG	IL10RB	IL13	IL17A	IL17B	IL17C	IL17D	IL17F	IL17RA	IL17RC	IL17RE	IL18	IL18R1	IL18RAP	IL1A	IL1B	IL1F10	IL1R1	IL1RAP	IL1RL1	IL1RL2	IL1RN	IL20RA	IL22	IL22RA1	IL23A	IL23R	IL25	IL26	IL27	IL2RA	IL33	IL34	IL36A	IL36B	IL36G	IL36RN	IL37	IL4	IL4R	IL5	IL6	IL6R	IL9	INS	IRAK1	IRAK2	IRAK4	IRF5	IRGM	ITCH	ITGAL	ITGAM	ITGB1	ITGB2	ITIH4	JAK2	KDM4D	KDM6B	KIT	KLKB1	KLRG1	KNG1	KRT16	LACC1	LAT	LBP	LCN2	LGALS9	LIAS	LOXL3	LRP1	LTB4R	LXN	LY75	LY86	LY96	LYN	LYZ	MACIR	MAP3K20	MAP3K7	MAPK9	MAPKAPK2	MAPT	MBL2	MDK	MEFV	MEP1B	MFHAS1	MGLL	MIF	MMP25	MRGPRX1	MSMP	MTOR	MYD88	NAIP	NAMPT	NCR3	NDST1	NFAM1	NFATC3	NFATC4	NFKB1	NFKBID	NFKBIZ	NFX1	NINJ1	NKG7	NLRC4	NLRP1	NLRP10	NLRP2	NLRP3	NLRP4	NLRP6	NLRP9	NOD1	NOS2	NOX1	NOX4	NPFF	NR1H4	NR3C1	NR4A1	NRROS	ODAM	OLR1	ORM1	ORM2	PARK7	PARP4	PF4	PF4V1	PIK3CD	PIK3CG	PJA2	PLA2G2A	PLA2G2D	PLA2G2E	PLA2G4B	PLA2G4C	PLD3	PLD4	PLGRKT	PLSCR1	PNMA1	PPBP	PRDX5	PRKCQ	PRKCZ	PRKD1	PRMT2	PROK2	PSEN1	PSTPIP1	PTAFR	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR	PTN	PTX3	PXK	PYCARD	PYDC2	PYDC5	RAC1	RARRES2	REG3A	REG3G	REL	RELA	RELB	RIPK1	RIPK2	RPS6KA4	RPS6KA5	S100A12	S100A8	S100A9	S1PR3	SAA1	SAA2	SAA4	SBNO1	SCG2	SCN11A	SCUBE1	SELE	SEMA7A	SERPINA1	SERPINA3	SERPINF2	SETD4	SIGIRR	SIGLEC1	SLAMF8	SLC11A1	SLC18A2	SMAD1	SMPDL3B	SNAP23	SNCA	SPINK7	STAB1	STAT3	STK39	SYK	TAB2	TAC1	TAC4	TACR1	TBK1	TBX21	TBXA2R	TFRC	TGFB1	THBS1	THEMIS2	TICAM1	TICAM2	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TMIGD3	TNF	TNFAIP3	TNFAIP6	TNFRSF1A	TNFRSF1B	TNFRSF4	TNFSF4	TNIP1	TNIP2	TNIP3	TOLLIP	TRADD	TRAF2	TRAF3IP2	TRAF5	TREM2	TRIL	TRIM14	TRIM21	TRIM31	TSPAN18	TUSC2	TXNIP	TYROBP	USP14	VCAM1	VNN1	VPS54	WNK4	WNT5A	XCL1	XCL2	XCR1	ZBP1	ZC3H12A	ZEB2	ZNF580
KE486_systemic_inflammation_leading_to_hepatic_steatosis_GO:0019915	lipid storage	ADIG	ANGPTL3	APOC4	APOE	AUP1	BSCL2	CAV1	CD36	CDS1	CDS2	CIDEA	CIDEB	CIDEC	CRY1	CRY2	DAB2IP	DGAT1	DGAT2	FFAR2	FITM1	FITM2	LDAF1	LDAH	LRAT	MOSPD2	NRIP1	PISD	PLA2G4C	PLIN2	PLIN3	PLIN5	PNPLA2	RAB40C	RNF213	SMIM22	SOAT1	SQLE	STARD4	ZFYVE1
KE57_Proliferation_Cell_proliferation_in_the_absence_of_cytotoxicity_GO:0008283	cell population proliferation	ABCB1	ABL1	ACE	ACVR1C	ACVRL1	AKNA	AKT1	ALKBH3	ANG	ANKRD45	AREG	ARHGEF2	ARIH2	ARTN	ATAD5	ATF2	ATF5	ATOH8	BAD	BAP1	BCL2	BGLAP	BMP10	BMP2	BMP4	BMP7	BMPER	BMPR2	BOP1	BRAT1	BTBD10	BTK	BTN3A1	C6orf89	CCN3	CD180	CD19	CD209	CD34	CD40	CD40LG	CD70	CD79A	CDC25A	CDC25C	CDH13	CDK3	CDK5RAP3	CDK9	CEACAM1	CEBPA	CEBPB	CEMP1	CEP120	CER1	CITED2	CLDN18	CLEC12B	CLU	CNTNAP2	COL3A1	CR2	CRK	CSF1	CSF1R	CTPS1	CUL4A	CUL4B	CX3CL1	DBN1	DCAF4	DCT	DDB1	DDIT3	DDR2	DDX41	DIO3	DIPK2A	DISC1	DIXDC1	DLG1	DLX3	DLX5	DMRT1	DOCK7	DOCK8	DSG2	DUX4L9	EBI3	EDNRA	EEF2	EGR1	ELAVL1	ELF4	EML1	EMP2	ENPEP	EPHA2	EPHB1	ERBB2	EREG	ERN1	ETV6	F2RL1	FABP4	FABP7	FAM83A	FAM83B	FAM83D	FAP	FBXW8	FERMT1	FES	FGF10	FGF13	FGF2	FGF4	FGF7	FGFR1	FGFR2	FGFR3	FGL1	FIGNL1	FLT3	FOS	FOXC1	GAPT	GLUL	GPC3	GSTP1	HEATR1	HELLS	HMGA2	HMGB1	HMOX1	HOOK3	HSPD1	ICAM3	ID2	IFNB1	IGF1	IGFBP5	IL10	IL17A	IL33	IL34	IL6	IRF2	ITGB1BP1	JUND	KANK1	KCNA1	KIF14	KIT	KLK8	KRAS	KRT2	LARP1	LIG4	LILRB1	LMBR1L	LOXL2	LTK	LYN	MAP4K1	MECOM	MEF2C	MEGF10	MELK	MIOS	MKI67	MMP14	MRPS27	MS4A1	MSN	MSX1	MT-RNR1	MTSS1	MUS81	MUSTN1	MVP	MYB	MYC	NAA35	NAA60	NDRG4	NDUFS2	NELFB	NES	NF2	NFIB	NFKBIZ	NKX3-1	NKX6-1	NMB	NOG	NOTCH1	NOX5	NPPC	NPR2	NPR3	NR4A3	NRARP	NUMB	NUMBL	OGFOD1	OR51E2	OSR1	OSR2	OTUD6B	PAFAH1B1	PAK5	PCM1	PCYT1A	PDGFRB	PDK1	PDS5B	PENK	PES1	PIK3CG	PLXNB2	POC1B	POLDIP2	POLR3G	PPARD	PPP3CB	PRDX1	PRKX	PROK1	PROK2	PTPRC	RAB10	RACGAP1	RASGRP1	RBX1	RETNLB	RHBDF1	RNF43	ROR1	RORA	RPS6KA1	RUNX1	RUNX2	SCRIB	SDCBP2	SDR16C5	SEMA5A	SERPINB1	SETMAR	SFRP2	SHH	SIX2	SIX3	SKI	SLAMF1	SLC11A1	SLC20A1	SLC26A2	SLC2A4	SLC39A5	SOX11	SOX4	SOX5	SOX9	SQSTM1	STAT1	STC1	TBCK	TBX1	TBX2	TEAD3	TEK	TGFA	TGFB2	TGFBI	TGFBR1	TGFBR3	THAP1	THPO	TMEM14B	TNFRSF14	TNFRSF4	TNFSF14	TNFSF18	TREM2	TRIM3	TRIM71	TRNP1	TWIST1	TYK2	UBE2L3	USP13	USP28	USPL1	VAV1	WNT1	WNT10B	WNT16	WNT2	WNT2B	WNT3	WNT3A	WNT5A	WNT7A	WNT7B	XBP1	YAP1	YJEFN3	YME1L1	YPEL5	YTHDF2	YY1AP1	ZEB2	ZNF324	ZNF416	ZNF503	ZNRF3	ZPR1
KE716_Increase_cell_proliferation_hepatocytes_GO:0072574	hepatocyte proliferation	CEBPB	FGL1	IL6	RPS6KA1	TGFA
KE724_Inhibition_Pyruvate_dehydrogenase_kinase_PDK_enzyme_GO:0010510	regulation of pyruvate decarboxylation to acetyl-CoA	BCKDK	PDK1	PDK2	PDK3	PDK4	PDP1	PDPR	PGK1	SIRT4	TPK1
KE726_Increased_Induction_of_pyruvate_dehydrogenase_PDH_GO:0006086	pyruvate decarboxylation to acetyl-CoA	DLAT	DLD	PDHA1	PDHA2	PDHB	PDHX
KE768_Increase_Cytotoxicity_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE769_Increase_Oxidative_metabolism_GO:0045333	cellular respiration	ACO1	ACO2	ADPGK	ADSL	AIFM2	ALDOA	ALDOB	ALDOC	ATP5F1A	ATP5F1B	ATP5F1C	ATP5F1D	ATP5F1E	ATP5F1EP2	ATP5ME	ATP5MF	ATP5MG	ATP5PB	ATP5PD	ATP5PF	ATP5PO	BLOC1S1	BPGM	C2orf69	CHCHD5	COQ10A	COQ10B	COX4I1	COX4I2	COX5A	COX5B	COX6A1	COX6A2	COX6B1	COX6B2	COX6C	COX7A1	COX7A2	COX7A2L	COX7A2P2	COX7B	COX7B2	COX7C	COX8A	COX8C	COXFA4	CS	CSKMT	CYC1	CYCS	DGUOK	DHTKD1	DLAT	DLD	DLST	ENO1	ENO2	ENO3	ENO4	ETFA	ETFB	ETFDH	FH	FOXK1	FOXK2	FOXRED1	GAPDH	GAPDHS	GCK	GPI	HCCS	HIGD1A	HIGD2A	HK1	HK2	HK3	HKDC1	IDH1	IDH2	IDH3A	IDH3B	IDH3G	KGD4	LDHA	LYRM7	MDH1	MDH1B	MDH2	MFN2	MT-ATP6	MT-ATP8	MT-CO1	MT-CO2	MT-CO3	MT-CYB	MT-ND1	MT-ND2	MT-ND3	MT-ND4	MT-ND4L	MT-ND5	MT-ND6	MTFR1	MTFR1L	MTFR2	MTLN	NDUFA1	NDUFA10	NDUFA11	NDUFA12	NDUFA13	NDUFA2	NDUFA3	NDUFA5	NDUFA6	NDUFA7	NDUFA8	NDUFA9	NDUFAB1	NDUFAF1	NDUFB1	NDUFB10	NDUFB11	NDUFB2	NDUFB3	NDUFB4	NDUFB5	NDUFB6	NDUFB7	NDUFB8	NDUFB9	NDUFC1	NDUFC2	NDUFC2-KCTD14	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS6	NDUFS7	NDUFS8	NDUFV1	NDUFV2	NDUFV3	NNT	NR4A3	OGDH	OGDHL	OXA1L	PDHA1	PDHA2	PDHB	PDHX	PFKFB1	PFKFB2	PFKFB3	PFKFB4	PFKL	PFKM	PFKP	PGAM1	PGAM2	PGAM4	PGK1	PGK2	PGM1	PINK1	PKLR	PKM	PLEC	PPARGC1A	PUM2	SDHA	SDHAF2	SDHAF4	SDHB	SDHC	SDHD	SIRT3	SLC25A13	SLC25A14	SLC25A51	STOML2	SUCLA2	SUCLG1	SUCLG2	SURF1	TPI1	TTC19	UCN	UCP2	UQCC3	UQCC4	UQCR10	UQCR11	UQCRB	UQCRC1	UQCRC2	UQCRFS1	UQCRFS1P1	UQCRH	UQCRHL	UQCRQ	VPS54
KE739_Increase_Hypertrophy_and_proliferation_follicular_cell_GO:0016049	cell growth	ADCY10	ALCAM	APP	ARIH2	AUTS2	BDNF	BIN3	BSG	C9orf72	CDK5	CDKL3	COBL	CPNE1	CTDSPL2	CTNNB1	CYFIP1	CYFIP2	DCAF13	DCLK1	EDN1	EDN2	EDN3	EDNRA	EFNA5	EIF2AK4	FLRT1	FLRT3	FOXL2	GATA4	IMPACT	ITGA4	KMT2D	LLPH	MAP1B	MEIS1	NLGN3	NPPA	NPR2	NRN1	NRN1L	NRP1	NRP2	PDLIM5	PLXNA3	PPP3CB	PRICKLE1	PRKG1	RARG	S100B	SEMA3A	SEMA3F	SEMA5A	SEMA5B	SH3GL2	SLC39A12	SLC9A6	SLIT1	SLIT2	SLIT3	SNX32	SORBS2	SOX9	SPAG6	SSNA1	ST8SIA2	TMEM108	TNN	TSC22D4	ULK1	ULK2	USP9X	WASF1
KE786_Increase_Cytotoxicity_hepatocytes_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE787_Increase_Regenerative_cell_proliferation_hepatocytes_GO:0072574	hepatocyte proliferation	CEBPB	FGL1	IL6	RPS6KA1	TGFA
KE828_Inhibition_Phospholipase_A_GO:0009395	phospholipid catabolic process	ABHD12	ABHD12B	ABHD16A	ABHD16B	ABHD6	ANGPTL3	APOA2	ENPP2	ENPP6	GDE1	GDPD1	GDPD3	GPCPD1	INPP5F	LIPC	LIPG	NAPEPLD	PAFAH1B1	PAFAH1B2	PAFAH1B3	PLA2G10	PLA2G15	PLA2G4A	PLA2G4B	PLA2G4C	PLA2G4D	PLA2G4E	PLA2G4F	PLA2G5	PLA2G6	PLA2G7	PLB1	PLCB1	PLCG1	PLCG2	PLD1	PLD2	PLPP6	PNLIPRP2	PNPLA6	PNPLA7	PNPLA8	PRDX6	SMPD1	SMPD2	SMPD3	SMPD4	SMPDL3B	SYNJ1
KE860_Decreased_Mitochondrial_Fatty_Acid_Beta_Oxidation_GO:0006635	fatty acid beta-oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ADIPOQ	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HADH	HADHA	HADHB	HSD17B10	HSD17B4	IVD	MCAT	MTLN	PEX2	PPARD	SCP2	SLC25A17	SLC27A2
KE8_Decreased_3_hydroxyacyl_CoA_dehydrogenase_type_2_activity_GO:0006635	fatty acid beta-oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ADIPOQ	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HADH	HADHA	HADHB	HSD17B10	HSD17B4	IVD	MCAT	MTLN	PEX2	PPARD	SCP2	SLC25A17	SLC27A2
KE80_Up_Regulation_CYP1A1_GO:0006805	xenobiotic metabolic process	AADAC	ABCB1	ABCB11	ABCC1	ABCC2	ABCC3	ABCC4	ABCC5	ABHD10	ACAA1	ACSL1	ACSM1	ACSM2B	ADA	AHR	AHRR	AKR1C1	ALDH2	ALDH3A1	AOC2	AOX1	ARNT	ARNT2	AS3MT	BCHE	BPHL	CAD	CBR1	CBR3	CES2	CES3	CMBL	CRYZ	CYB5B	CYP1A1	CYP1A2	CYP1B1	CYP26A1	CYP26B1	CYP2A13	CYP2A6	CYP2A7	CYP2B6	CYP2C18	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP2D7	CYP2E1	CYP2F1	CYP2J2	CYP2R1	CYP2S1	CYP2U1	CYP2W1	CYP3A4	CYP3A5	CYP3A7	CYP46A1	CYP4F12	CYP4F2	DPYD	EPHX1	FMO2	FMO4	FMO5	GLYAT	GRIN1	GSTA1	GSTA2	GSTA3	GSTA4	GSTA5	GSTM1	GSTM2	GSTM3	GSTM4	GSTO1	GSTO2	GSTP1	GUK1	HEMK2	HNF4A	NAT1	NAT2	NOS1	NQO1	NR1I2	NUDT15	PRKCE	RBBP9	RORA	RORC	S100A12	SLC22A1	SLC22A7	SLC28A2	SLC28A3	SLC29A1	SLC29A3	SLCO1A2	SLCO1B1	SLCO1B3	SLCO2B1	SMOX	SULT1A1	SULT1A2	SULT1A3	SULT1B1	SULT1C3	SULT1C4	SULT2A1	TPMT	UGT1A1	UGT1A10	UGT1A3	UGT1A6	UGT1A7	UGT1A8	UGT1A9	UGT2A1	UGT2A2	UGT2A3	UGT2B11	UGT2B15	UGT2B17	UGT2B4	UGT2B7	UPP2	VKORC1
KE878_Inhibition_SREBP1c_GO:0032933	SREBP signaling pathway	ARHGEF10L	ERLIN1	ERLIN2	INSIG1	INSIG2	SCAP	SREBF1	SREBF2
KE879_Activation_MTTP_GO:0034379	very-low-density lipoprotein particle assembly	ACSL3	APOB	APOC1	APOC3	CIDEB	DGAT1	LPCAT3	MFSD2A	MTTP	SOAT1	SOAT2
KE880_Increased_ApoB100_GO:0034379	very-low-density lipoprotein particle assembly	ACSL3	APOB	APOC1	APOC3	CIDEB	DGAT1	LPCAT3	MFSD2A	MTTP	SOAT1	SOAT2
KE881_Increased_Triglyceride_GO:0019432	triglyceride biosynthetic process	ACSL1	AGMO	AGPAT2	DGAT1	DGAT2	GK	GPAM	GPAT2	GPAT3	GPAT4	LPGAT1	LPIN1	LPIN2	LPIN3	MOGAT1	MOGAT2	MOGAT3	PNPLA3	TMEM68
KE881_Increased_Triglyceride_GO:0019433	triglyceride catabolic process	APOA5	APOC3	CPS1	FABP1	FABP12	FABP2	FABP3	FABP4	FABP5	FABP6	FABP7	FABP9	GPIHBP1	LIPC	LIPE	LIPG	LPL	MGLL	PLB1	PNLIP	PNLIPRP1	PNLIPRP2	PNLIPRP3	PNPLA1	PNPLA2	PNPLA3	PNPLA4	PNPLA5
KE2224_Dysregulation_of_transcriptional_expression_within_PPAR_signaling_network_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE2225_Disrupted_Lipid_Storage_GO:0019915	lipid storage	ADIG	ANGPTL3	APOC4	APOE	AUP1	BSCL2	CAV1	CD36	CDS1	CDS2	CIDEA	CIDEB	CIDEC	CRY1	CRY2	DAB2IP	DGAT1	DGAT2	FFAR2	FITM1	FITM2	LDAF1	LDAH	LRAT	MOSPD2	NRIP1	PISD	PLA2G4C	PLIN2	PLIN3	PLIN5	PNPLA2	RAB40C	RNF213	SMIM22	SOAT1	SQLE	STARD4	ZFYVE1
KE2226_Stressor_binding_PPAR_isoforms_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE2227_Disrupted_PPAR_isoform_nuclear_signaling_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE1104_Decreased_Prostaglandin_F2alpha_concentration_plasma_GO:0006693	prostaglandin metabolic process	ACOX1	AKR1B1	AKR1C1	AKR1C2	AKR1C3	AKR1C4	CD74	CES2	CTHRC1	CYP2S1	CYP4F8	DAGLB	GSTA1	GSTM1	GSTP1	HPGD	HPGDS	MIF	PLA2G10	PLA2G4A	PNPLA8	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGR1	PTGR2	PTGR3	PTGS1	PTGS2	SIGMAR1	TBXAS1	TNFRSF1A
KE1106_Occurrence_cardiac_arrhythmia_GO:0061337	cardiac conduction	ABCC9	ACE	AKAP9	ANK2	ATP1A1	ATP1A2	ATP1A3	ATP1B1	ATP1B2	BIN1	CACNA1C	CACNA1D	CACNA1G	CACNA2D1	CACNB2	CAMK2D	CASQ2	CAV1	CTNNA3	CXADR	DSC2	DSG2	DSP	GJA1	GJA5	GJC1	GJD3	HCN1	HCN3	HCN4	ISL1	JUP	KCNA5	KCND3	KCNE1	KCNE2	KCNE3	KCNE4	KCNE5	KCNH2	KCNH6	KCNJ2	KCNJ3	KCNJ5	KCNN2	KCNQ1	PKP2	PRKACA	RYR2	SCN10A	SCN1B	SCN2B	SCN3B	SCN4B	SCN5A	SLC4A3	SLC8A1	SLC9A1	SPTBN4	SRC	TBX5	TMEM65	TNNI3K	TRPM4	YWHAE
KE1171_Increase_Clonal_Expansion_of_Altered_Hepatic_Foci_GO:0072574	hepatocyte proliferation	CEBPB	FGL1	IL6	RPS6KA1	TGFA
KE1177_Decreased_Ionotropic_GABA_receptor_chloride_channel_conductance_GO:0007214	gamma-aminobutyric acid signaling pathway	ATF4	GABBR1	GABBR2	GABRA1	GABRA2	GABRA3	GABRA4	GABRA5	GABRA6	GABRB1	GABRB2	GABRB3	GABRD	GABRE	GABRG1	GABRG2	GABRG3	GABRQ	GABRR1	GABRR3	GNAI2	GPR156	PLCL1	PLCL2	SHISA7	SLC12A2
KE1270_Inactivation_of_PPAR_GO:0035357	peroxisome proliferator activated receptor signaling pathway	ACTN4	ALOXE3	FAM120B	NCOA1	NCOA2	PDK3	PPARA	PPARG	RXRA
KE1271_Activation_of_TGF_signaling_GO:0007179	transforming growth factor beta receptor signaling pathway	ACVR1	ACVRL1	ADAM9	APPL1	APPL2	ARRB2	BAMBI	BMPR1A	CDH5	CDKN2B	CITED1	CLDN5	COL1A2	COL3A1	CREB1	DAB2	DUSP22	EID2	ENG	FERMT2	FMOD	FNTA	FOS	FOXH1	FSHB	FURIN	GCNT2	GDF10	GDF11	GDF15	GDF5	GDF9	HPGD	ID1	ITGB5	JUN	LEFTY1	LRRC32	LTBP2	LTBP3	MAP3K7	MSTN	NLK	NRROS	PARP1	PSG9	PTK2	PTPRK	PXN	RGCC	SIRT1	SKI	SMAD1	SMAD2	SMAD3	SMAD4	SMAD5	SMAD7	SMAD9	SPI1	SRC	STAT3	TGFB1	TGFB2	TGFB3	TGFBR1	TGFBR2	TGFBR3	TGFBR3L	TGFBRAP1	USP15	USP9X	USP9Y	WFIKKN1	WFIKKN2	ZFYVE9	ZMIZ1	ZYX
KE1275_Collagen_Deposition_GO:0032964	collagen biosynthetic process	ADAMTS3	COL1A1	COL5A1	P3H3	P3H4	PCOLCE	PLOD1	PLOD2	PLOD3	RCN3	TMEM131	TRAM2	TRAPPC8
KE1276_Lung_fibrosis_GO:0030198	extracellular matrix organization	ADAM10	ADAM15	ADAM8	ADAMTS1	ADAMTS10	ADAMTS12	ADAMTS13	ADAMTS14	ADAMTS15	ADAMTS16	ADAMTS17	ADAMTS18	ADAMTS19	ADAMTS2	ADAMTS20	ADAMTS3	ADAMTS4	ADAMTS5	ADAMTS6	ADAMTS7	ADAMTS8	ADAMTS9	ADAMTSL1	ADAMTSL2	ADAMTSL3	ADAMTSL5	APLP1	APP	ATP7A	BMP1	C6orf15	CCDC80	CLASP1	CLASP2	CMA1	COL10A1	COL11A1	COL11A2	COL12A1	COL13A1	COL14A1	COL15A1	COL16A1	COL17A1	COL18A1	COL19A1	COL1A1	COL1A2	COL22A1	COL23A1	COL24A1	COL27A1	COL28A1	COL2A1	COL3A1	COL4A1	COL4A2	COL4A3	COL4A4	COL4A5	COL4A6	COL5A1	COL5A2	COL5A3	COL6A5	COL6A6	COL7A1	COL8A1	COL8A2	COL9A1	COL9A2	COL9A3	COLEC12	COLGALT1	COLGALT2	COLQ	CREB3L1	CRTAP	CTSG	CTSK	CTSS	CTSV	CYP1B1	DAG1	DDR2	DMP1	DPT	ECM2	EFEMP2	ELANE	ELN	EMILIN1	EXOC8	FBLN1	FBLN5	FERMT1	FLOT1	FLRT2	FMOD	FURIN	GAS6	GFOD2	GPM6B	GREM1	HAS1	HAS2	HAS3	HMCN1	HPN	HPSE2	IBSP	ITGA2	ITGB1	KIF9	KLK4	KLK5	KLK7	LAMC1	LOX	LOXL1	LOXL2	LOXL3	LOXL4	LUM	MANSC4	MARCO	MATN1	MATN2	MATN3	MATN4	MFAP4	MIA	MMP1	MMP10	MMP11	MMP12	MMP13	MMP14	MMP15	MMP16	MMP17	MMP19	MMP2	MMP20	MMP21	MMP23B	MMP24	MMP25	MMP26	MMP27	MMP28	MMP3	MMP7	MMP8	MMP9	MPV17	MYH11	MYO1E	NDNF	NF1	NID1	NID2	NOXO1	NPHS1	NPNT	NTN4	OPTC	OTOL1	P3H4	P4HA1	P4HA3	PAPLN	PHLDB1	PHLDB2	PLG	PLOD1	PLOD2	PLOD3	POSTN	PRICKLE1	PRSS1	PRSS2	PXDN	PXDNL	QSOX1	RAMP2	RECK	SCX	SERPINF2	SERPINH1	SH3PXD2B	SLC39A8	SMOC1	SMOC2	SPINK5	SPINT1	SPOCK2	ST7	SULF1	SULF2	TGFB1	TGFB2	TGFBI	TGFBR1	TGM2	TLL1	TLL2	TMPRSS6	TNXB	TPSAB1	VIT	WASHC1	WT1
KE1289_Perturbation_of_cholesterol_GO:0042632	cholesterol homeostasis	ABCA1	ABCA2	ABCA5	ABCB11	ABCG1	ABCG4	ABCG5	ABCG8	ACSM1	ACSM3	AKR1C1	ANGPTL3	APOA1	APOA2	APOA4	APOA5	APOB	APOC2	APOC3	APOE	APOM	CAV1	CAV3	CD24	CES1	CETP	CNBP	CYP39A1	CYP7A1	CYP7B1	DCTN1	DGAT2	DISP3	EHD1	EPHX2	FABP3	FGFR4	FURIN	GPIHBP1	GRAMD1B	HDAC9	HNF4A	HSDL2	IL18	INSIG1	LAMTOR1	LCAT	LDAH	LDLR	LDLRAP1	LIMA1	LIPC	LIPG	LPL	LRP5	MALL	MED13	MINAR2	MTTP	MYLIP	NEGR1	NPC1	NPC1L1	NPC2	NR1D1	NR1H2	NR1H3	NR1H4	OSBPL1A	PCSK5	PCSK9	PLA2G10	PLA2G12B	PLPP6	PNLIP	PNLIPRP1	PNLIPRP2	PNLIPRP3	RAB7A	RALY	RILP	RORA	SCARB1	SIRT1	SOAT1	SOAT2	TMEM97	TSKU	TSPO	TTC39B	VAPA	XBP1
KE1305_Increase_cytosolic_fatty_acid_GO:0006631	fatty acid metabolic process	AACS	AASDH	ABCB11	ABCD1	ABCD2	ABCD3	ABCD4	ABHD1	ABHD12	ABHD2	ABHD3	ABHD5	ABHD6	ACAA1	ACAA2	ACACA	ACACB	ACAD10	ACAD11	ACAD9	ACADL	ACADM	ACADS	ACADSB	ACADVL	ACAT1	ACAT2	ACBD4	ACBD5	ACBD7	ACLY	ACOT1	ACOT11	ACOT12	ACOT2	ACOT4	ACOT6	ACOT7	ACOT7L	ACOT8	ACOT9	ACOX1	ACOX2	ACOX3	ACOXL	ACSBG1	ACSBG2	ACSF2	ACSF3	ACSL1	ACSL3	ACSL4	ACSL5	ACSL6	ACSM1	ACSM2A	ACSM2B	ACSM3	ACSM4	ACSM5	ACSM6	ACSS1	ACSS2	ADH4	ADH5	ADH7	ADIPOQ	ADIPOR1	ADIPOR2	ADTRP	AIG1	AKR1B1	AKR1C1	AKR1C2	AKR1C3	AKR1C4	ALDH3A2	ALKBH7	ALOX12	ALOX12B	ALOX15	ALOX15B	ALOX5	ALOXE3	AMACR	ANGPTL3	AOAH	ASAH1	ASAH2	AUH	AWAT1	BAAT	BDH2	BRCA1	C3	CBR1	CBR4	CD36	CD74	CES1	CES1P1	CES2	CPT1A	CPT1B	CPT1C	CPT2	CRAT	CROT	CRYL1	CTHRC1	CYGB	CYP1A1	CYP1A2	CYP1B1	CYP2A13	CYP2A6	CYP2A7	CYP2B6	CYP2C18	CYP2C19	CYP2C8	CYP2C9	CYP2D6	CYP2D7	CYP2E1	CYP2F1	CYP2J2	CYP2S1	CYP2U1	CYP3A4	CYP4A11	CYP4A22	CYP4B1	CYP4F11	CYP4F12	CYP4F2	CYP4F3	CYP4F8	CYP4V2	CYP4Z1	DAGLA	DAGLB	DBI	DECR1	DECR2	DEGS1	ECH1	ECHDC1	ECHDC2	ECHDC3	ECHS1	ECI1	ECI2	EHHADH	ELOVL1	ELOVL2	ELOVL3	ELOVL4	ELOVL5	ELOVL6	ELOVL7	EPHX1	ETFA	ETFB	ETFDH	FA2H	FAAH	FAAH2	FABP2	FABP3	FADS1	FADS2	FADS2B	FADS3	FADS6	FASN	GCDH	GGT1	GGT5	GLYATL2	GPX1	GPX4	GSTA1	GSTM1	GSTM2	GSTM4	GSTP1	HACD1	HACD2	HACD3	HACD4	HACL1	HACL2	HADH	HADHA	HADHB	HAO1	HAO2	HPGD	HPGDS	HSD17B10	HSD17B12	HSD17B4	HSD17B8	HTD2	IVD	LEP	LIAS	LIPC	LIPG	LPIN1	LPIN2	LPIN3	LPL	LTC4S	LYPLA1	LYPLA2	MBLAC2	MCAT	MCEE	MECR	MGLL	MGST3	MIF	MLYCD	MORC2	MSMO1	MTLN	NAAA	NDUFAB1	NUDT19	NUDT7	NUDT8	OLAH	OXSM	PCCA	PCCB	PECR	PEDS1	PER2	PEX13	PEX2	PHYH	PLA2G10	PLA2G15	PLA2G1B	PLA2G2F	PLA2G4A	PLA2G4B	PLA2G4C	PLA2G4D	PLA2G5	PM20D1	PNLIP	PNLIPRP1	PNLIPRP2	PNLIPRP3	PNPLA3	PNPLA8	POR	PPARA	PPARD	PPARG	PPARGC1A	PRKAA1	PRKAA2	PRKAB1	PRKAB2	PRKAG1	PRKAG2	PRKAG3	PRXL2B	PTGDS	PTGES	PTGES2	PTGES3	PTGIS	PTGR1	PTGR2	PTGR3	PTGS1	PTGS2	SCD	SCD5	SCP2	SGPL1	SIGMAR1	SLC25A17	SLC27A1	SLC27A2	SLC27A3	SLC27A4	SLC27A5	SLC27A6	TBXAS1	TECR	TECRL	THEM4	THEM5	TMEM135	TNFRSF1A	UGT1A8	XBP1
KE1305_Increase_cytosolic_fatty_acid_GO:0015908	fatty acid transport	ABCC4	ABCD1	ABCD2	ABCD3	ABCD4	ACE	ACSL1	ACSL3	APOE	BDKRB2	CD36	CPT1A	CPT1B	CPT2	CRABP1	CRABP2	DRD2	DRD3	DRD4	FABP1	FABP12	FABP2	FABP3	FABP4	FABP5	FABP5P3	FABP6	FABP7	FABP9	GOT2	LEP	LYN	LYPLA1	MFSD2A	NMB	NMUR2	NOS2	OC90	PLA2G10	PLA2G12A	PLA2G12B	PLA2G1B	PLA2G2A	PLA2G2C	PLA2G2D	PLA2G2E	PLA2G2F	PLA2G3	PLA2G4A	PLA2G5	PMP2	PNPLA8	PPARD	PPARG	PROCA1	RBP1	RBP2	RBP5	RBP7	RPS6KB1	SLC22A1	SLC22A11	SLC22A2	SLC22A6	SLC22A7	SLC22A8	SLC22A9	SLC25A17	SLC25A20	SLC27A1	SLC27A2	SLC27A3	SLC27A4	SLC27A5	SLC27A6	SLC2A1	SLC43A3	SLC5A8	SLCO1B1	SLCO2A1	SLCO2B1	SLCO3A1	SLCO4A1	SPX	THRSP	UCP2
KE1349_Activated_presynaptic_neuron_1_GO:0098928	presynaptic signal transduction	SIPA1L2
KE1362_Increased_hippocampal_hyperdepolarization_GO:0051899	membrane depolarization	ABL1	ADORA2A	ANK2	ASIC3	ATP1A2	ATP5IF1	BEST2	CACNA1C	CACNA1D	CACNA1G	CACNA2D1	CACNB2	CAV1	CHRNA1	CHRNA10	CHRNA2	CHRNA3	CHRNA4	CHRNA5	CHRNA6	CHRNA9	CHRNB1	CHRNB2	CHRNB3	CHRNB4	CHRND	CHRNE	CHRNG	CNGB1	EDN1	HCN2	HCN4	KCNH2	KCNJ2	KMT2A	P2RX4	P2RX7	SCN10A	SCN11A	SCN1A	SCN1B	SCN2B	SCN3A	SCN3B	SCN4B	SCN5A	SCN8A	SCN9A	SLC6A4	SLC8A1	TRPC4	TRPM4	YWHAH
KE1365_Increase_Apoptosis_GO:0006915	apoptotic process	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CEACAM5	CEACAM6	CEBPB	CECR2	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FNIP2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA2	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLLN	KMT2A	KREMEN1	KRT20	LALBA	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NISCH	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NUAK2	NUDT2	OGT	OPA1	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNW1	SOD2	SORT1	SPI1	SPIN2B	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1352_Activated_voltage_gated_sodium_channel_GO:0035725	sodium ion transmembrane transport	A0ABB0MV19	ANO6	ASIC1	ASIC2	ASIC3	ASIC4	ASIC5	ATP12A	ATP1A1	ATP1A2	ATP1A3	ATP1A4	ATP1B1	ATP1B2	ATP1B3	ATP4A	ATP4B	CHP1	CNGA1	CNGA3	CNGB1	CNNM4	FXYD1	FXYD2	FXYD3	FXYD4	FXYD5	FXYD6	FXYD7	GRIN1	GRIN2A	HCN1	HCN2	HCN3	HCN4	KCNK1	KCNK3	KCNK9	MCOLN1	MCOLN3	NALCN	NALF1	OSR1	P2RX7	PKD2	PKD2L1	SCN10A	SCN11A	SCN1A	SCN1B	SCN2A	SCN2B	SCN3A	SCN3B	SCN4A	SCN4B	SCN5A	SCN7A	SCN8A	SCN9A	SCNN1A	SCNN1B	SCNN1D	SCNN1G	SHROOM2	SLC12A1	SLC12A2	SLC12A3	SLC13A1	SLC13A2	SLC13A3	SLC13A4	SLC13A5	SLC17A1	SLC17A2	SLC17A3	SLC17A4	SLC17A6	SLC17A7	SLC17A8	SLC20A1	SLC20A2	SLC23A1	SLC24A1	SLC24A2	SLC24A3	SLC24A4	SLC24A5	SLC28A3	SLC34A1	SLC34A2	SLC34A3	SLC38A1	SLC38A2	SLC38A4	SLC38A5	SLC41A1	SLC41A3	SLC4A10	SLC4A11	SLC4A4	SLC4A5	SLC4A7	SLC4A8	SLC4A9	SLC5A1	SLC5A10	SLC5A12	SLC5A2	SLC5A3	SLC5A4	SLC5A5	SLC5A6	SLC5A8	SLC5A9	SLC60A2	SLC6A1	SLC6A11	SLC6A12	SLC6A13	SLC6A14	SLC6A15	SLC6A16	SLC6A17	SLC6A18	SLC6A19	SLC6A2	SLC6A20	SLC6A3	SLC6A4	SLC6A5	SLC6A6	SLC6A7	SLC6A8	SLC6A9	SLC8A1	SLC8A2	SLC8A3	SLC8B1	SLC9A1	SLC9A2	SLC9A3	SLC9A4	SLC9A5	SLC9A6	SLC9A7	SLC9A8	SLC9A9	SLC9B1	SLC9B2	SLC9C1	SLC9C2	STK39	TMEM43	TMEM65	TPCN1	TPCN2	TRPM2	TRPM4	TRPM5	TRPV3	UNC79	UNC80	WNK1	WNK4
KE1355_Activated_membrane_depolarization_GO:0051899	membrane depolarization	ABL1	ADORA2A	ANK2	ASIC3	ATP1A2	ATP5IF1	BEST2	CACNA1C	CACNA1D	CACNA1G	CACNA2D1	CACNB2	CAV1	CHRNA1	CHRNA10	CHRNA2	CHRNA3	CHRNA4	CHRNA5	CHRNA6	CHRNA9	CHRNB1	CHRNB2	CHRNB3	CHRNB4	CHRND	CHRNE	CHRNG	CNGB1	EDN1	HCN2	HCN4	KCNH2	KCNJ2	KMT2A	P2RX4	P2RX7	SCN10A	SCN11A	SCN1A	SCN1B	SCN2B	SCN3A	SCN3B	SCN4B	SCN5A	SCN8A	SCN9A	SLC6A4	SLC8A1	TRPC4	TRPM4	YWHAH
KE1321_Increased_intracellular_sodium_Na_GO:0006883	intracellular sodium ion homeostasis	ATP12A	ATP1A1	ATP1A2	ATP1A3	ATP1A4	ATP1B1	ATP1B2	ATP1B3	ATP4A	ATP4B	CHP1	CHP2	FXYD1	FXYD3	FXYD4	FXYD5	FXYD6	FXYD7	SCNN1A	SCNN1B	SCNN1D	SCNN1G	SLC12A2	SLC8A1	SLC9A1	SLC9A3	TESC	TMPRSS3
KE1287_Glutathione_synthesis_GO:0006750	glutathione biosynthetic process	GCLC	GCLM	GGT1	GGT3P	GGT5	GGT6	GGT7	GSS	HAGH	MGST2	SLC1A1	SLC1A2
KE1490_Inhibition_Fatty_Acid_Beta_Oxidation_GO:0006635	fatty acid beta-oxidation	ABCD1	ABCD2	ABCD3	ABCD4	ACAA1	ACAA2	ACAD10	ACAD11	ACADL	ACADM	ACADS	ACADVL	ACAT1	ACOT8	ACOX1	ACOX2	ACOX3	ACOXL	ADIPOQ	AMACR	AUH	BDH2	CPT1A	CPT1B	CPT2	CRAT	CROT	DECR1	DECR2	ECH1	ECHDC1	ECHDC2	ECHS1	ECI1	ECI2	EHHADH	ETFA	ETFB	ETFDH	GCDH	HADH	HADHA	HADHB	HSD17B10	HSD17B4	IVD	MCAT	MTLN	PEX2	PPARD	SCP2	SLC25A17	SLC27A2
KE1825_Increase_Cell_death_GO:0008219	cell death	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALKBH7	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATG9A	ATG9B	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP14	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CDKN1B	CDKN2D	CEACAM5	CEACAM6	CEBPB	CECR2	CERS3	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYLD	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	EIF4G2	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FLG	FNIP2	FOSL2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMK	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA1	HTRA2	HTRA4	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IPMK	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPK1	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLK5	KLLN	KMT2A	KREMEN1	KRT1	KRT10	KRT2	KRT20	LALBA	LAMP1	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LIPK	LIPM	LIPN	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K20	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLKL	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NINJ1	NISCH	NKG7	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NTRK1	NUAK2	NUDT2	OGT	OPA1	OPTN	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PGAM5	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PI3	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PJVK	PKM	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGER3	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNCAIP	SNW1	SOD2	SORT1	SPATA2	SPG7	SPI1	SPIN2B	SPRR1A	SPRR2E	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	TGM1	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP1	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TRPM7	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2
KE1194_Increase_DNA_damage_GO:0006974	DNA damage response	A8MVJ9	ABL1	ABRAXAS1	ACD	ACER2	ACTL6A	ACTR5	ACTR8	ADPRS	AEN	AGER	AIM2	AKTIP	ALKBH1	ALKBH2	ALKBH3	ALKBH7	ALKBH8	ANKLE1	AP5S1	AP5Z1	APBB1	APC	APEX1	APEX2	APLF	APTX	ASCC1	ASCC2	ASCC3	ASF1A	ASH2L	ASTE1	ATAD3A	ATAD5	ATF2	ATM	ATMIN	ATP23	ATR	ATRIP	ATRX	ATXN3	AUNIP	BABAM1	BABAM2	BACH1	BAG6	BAK1	BARD1	BATF	BAX	BAZ1B	BCCIP	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L2	BCL3	BCL6	BCLAF1	BID	BIRC2	BIRC3	BKGD	BLM	BOD1L1	BOK	BRAT1	BRCA1	BRCA2	BRCC3	BRD4	BRD9	BRIP1	BRME1	BRSK1	BTG2	C1QBP	CASP2	CASP9	CBL	CBX1	CBX3	CBX5	CCAR2	CCDC13	CCND1	CCNH	CCNK	CDC14B	CDC45	CDC5L	CDC7	CDCA5	CDIP1	CDK1	CDK2	CDK3	CDK5RAP3	CDK6	CDK7	CDK9	CDKN1A	CDKN1B	CDKN2AIP	CDKN2D	CENPS	CENPX	CEP164	CEP63	CETN2	CFAP410	CGAS	CHAF1A	CHAF1B	CHCHD6	CHD1L	CHD4	CHEK1	CHEK2	CHRNA4	CIB1	CIDEB	CINP	CIP2A	CLOCK	CLSPN	COMMD1	CRADD	CRIP1	CRY1	CSNK1E	CSNK2A1	CSNK2A2	CSNK2A3	CTBP1-DT	CTLA4	CTPS1	CUL4A	CUL4B	CYREN	DBF4	DCLRE1A	DCLRE1B	DCLRE1C	DCPH1	DCUN1D5	DDB1	DDB2	DDIT3	DDIT4	DDX1	DDX11	DELE1	DGCR8	DMAP1	DMC1	DNA2	DNTT	DONSON	DOT1L	DTL	DTX3L	DYNLL1	DYRK1B	DYRK2	E2F1	E2F7	EEPD1	EGLN3	EID3	EIF2AK4	ELOF1	EME1	EME2	EMSY	ENDOG	ENDOV	EP300	EP400	EPC1	EPC2	EPHA2	ERCC1	ERCC2	ERCC3	ERCC4	ERCC5	ERCC6	ERCC6L	ERCC6L2	ERCC8	ETAA1	EXD2	EXO1	EXO5	EXOSC10	EYA1	EYA2	EYA3	EYA4	FAAP100	FAAP20	FAAP24	FAM111A	FAM111B	FAN1	FANCA	FANCB	FANCC	FANCD2	FANCE	FANCF	FANCG	FANCI	FANCL	FANCM	FBH1	FBXO31	FBXO45	FBXO5	FBXO6	FBXW7	FEN1	FH	FIGNL1	FIRRM	FLYWCH1	FMN2	FMR1	FNIP2	FOXM1	FOXN3	FOXO1	FOXP1	FTO	FZR1	GADD45A	GCNA	GEN1	GFI1	GGN	GINS2	GINS4	GML	GNB1L	GNL1	GRB2	GTF2H1	GTF2H2	GTF2H2C	GTF2H3	GTF2H4	GTF2H5	GTSE1	H2AC25	H2AX	HDAC10	HDAC3	HDGFL2	HELB	HELLS	HELQ	HERC2	HIC1	HINFP	HIPK1	HIPK2	HLTF	HMCES	HMGA2	HMGB1	HMGB2	HPF1	HROB	HSF1	HSF2BP	HTATSF1	HTRA2	HUS1	HUS1B	HUWE1	IER3	IFFO1	IFI16	IGHMBP2	IKBKE	IKBKG	ING2	INIP	INO80	INO80B	INO80C	INO80D	INO80E	INTS3	INTS7	IRF3	IRF7	JMY	KAT5	KAT7	KDM1A	KDM2A	KDM4D	KIF22	KIN	KMT5B	KMT5C	KRCC1	LIG1	LIG3	LIG4	LMNA	LYN	MACROD1	MACROD2	MACROH2A1	MAD2L2	MAP2K6	MAP3K20	MAP3K7	MAPK12	MAPK14	MAPK15	MAPK3	MAPKAPK2	MAPT	MASTL	MBD4	MBTD1	MBTPS1	MBTPS2	MC1R	MCL1	MCM10	MCM2	MCM3	MCM4	MCM5	MCM6	MCM7	MCM8	MCM9	MCMDC2	MCRS1	MCTS1	MDC1	MDM2	MDM4	MEIOB	MEIOC	MEN1	METTL14	METTL3	MGME1	MGMT	MICA	MLH1	MLH3	MLST8	MMS19	MMS22L	MNAT1	MNDA	MOAP1	MORC2	MORF4L1	MORF4L2	MPG	MPND	MRE11	MRNIP	MSH2	MSH3	MSH4	MSH5	MSH6	MSL2	MTA1	MTOR	MTREX	MUC1	MUS81	MUTYH	MYC	MYO6	NABP1	NABP2	NBN	NCOA6	NDRG1	NEDD4	NEIL1	NEIL2	NEIL3	NEK11	NEK4	NEURL4	NFAT5	NFATC2	NFRKB	NHEJ1	NIPBL	NKX3-1	NME3	NONO	NOP53	NPAS2	NPM1	NRBP1	NRBP2	NRDE2	NSD2	NSMCE1	NSMCE2	NSMCE3	NSMCE4A	NTHL1	NUAK1	NUCKS1	NUDT1	NUPR2	OARD1	OGG1	OTUB1	OTUD4	PAGR1	PAK1	PALB2	PARG	PARK7	PARP1	PARP10	PARP2	PARP3	PARP4	PARP9	PARPBP	PAXIP1	PAXX	PCLAF	PCNA	PDS5B	PELI1	PHF1	PHF13	PHLDA3	PIAS1	PIAS4	PIDD1	PIF1	PLK1	PLK2	PLK3	PLK5	PMAIP1	PML	PMS1	PMS2	PMS2P1	PMS2P2	PMS2P3	PMS2P5	PNKP	POGZ	POLA1	POLB	POLD1	POLD2	POLD3	POLD4	POLDIP2	POLE	POLE2	POLE3	POLG	POLH	POLI	POLK	POLL	POLM	POLN	POLQ	POLR2I	PPP1CA	PPP1R15A	PPP4C	PPP4R3A	PPP4R3B	PPP4R3C	PPP5C	PRAP1	PRDM9	PRIMPOL	PRKCD	PRKDC	PRMT1	PRMT6	PRPF19	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD14	PSME4	PTTG1	PWWP3A	PYCARD	RAD1	RAD17	RAD18	RAD21	RAD21L1	RAD23A	RAD23B	RAD50	RAD51	RAD51AP1	RAD51B	RAD51C	RAD51D	RAD52	RAD54B	RAD54L	RAD9A	RAD9B	RBBP4	RBBP5	RBBP6	RBBP8	RBM24	RBX1	RCHY1	REC8	RECQL	RECQL4	RECQL5	REV1	REV3L	REXO4	RFC1	RFC2	RFC3	RFC4	RFC5	RFWD3	RHNO1	RIF1	RINT1	RIPK1	RMI1	RMI2	RNASEH2A	RNASEH2B	RNASEH2C	RNF111	RNF113A	RNF138	RNF168	RNF169	RNF8	RPA1	RPA2	RPA3	RPA4	RPL26	RPS27L	RPS3	RPS6KA6	RPTOR	RRM1	RRM2	RRM2B	RTEL1	RUVBL1	RUVBL2	SAMHD1	SDE2	SEM1	SESN2	SETD1A	SETD2	SETD7	SETMAR	SETX	SFN	SFPQ	SFR1	SHLD1	SHLD2	SHLD3	SHPRH	SIRT1	SIRT4	SIRT6	SIRT7	SIX6OS1	SLC30A9	SLF1	SLF2	SLFN11	SLX1A	SLX4	SMARCA5	SMARCAD1	SMARCAL1	SMC1A	SMC3	SMC5	SMC6	SMCHD1	SMG1	SMUG1	SNW1	SP100	SPATA22	SPDYA	SPIDR	SPINDOC	SPO11	SPRTN	SSRP1	STK11	STK33	STK38	STUB1	STXBP4	SUMO1	SUPT16H	SUSD6	SUV39H1	SWI5	SWSAP1	SYCP1	TAF1	TAF9	TANK	TAOK1	TAOK2	TAOK3	TDG	TDP1	TDP2	TENT4A	TERF2	TERF2IP	TEX15	TEX264	TFAP4	TFDP3	TFIP11	TFPT	TICRR	TIGAR	TIMELESS	TIPIN	TIPRL	TLK1	TLK2	TMEM109	TNFRSF1B	TNKS1BP1	TNP1	TONSL	TOP2A	TOP3A	TOP3B	TOPBP1	TOPORS	TP53	TP53BP1	TP63	TP73	TRADD	TRAF2	TRAF5	TRAF6	TRAIP	TREX1	TREX2	TRIAP1	TRIM28	TRIM39	TRIP12	TRIP13	TRRAP	TTC5	TTF2	UACA	UBA1	UBA6	UBA7	UBE2A	UBE2B	UBE2D3	UBE2E2	UBE2N	UBE2T	UBE2U	UBE2V1	UBE2V2	UBE2W	UBQLN4	UBR5	UCHL5	UFL1	UHRF1	UIMC1	UNG	UPF1	URI1	USP1	USP10	USP16	USP28	USP3	USP43	USP44	USP45	USP47	USP51	USP7	USP9X	UVRAG	UVSSA	VAV3	VCP	VCPIP1	VRK1	VRK2	VRK3	WAC	WDHD1	WDR33	WDR4	WDR48	WDR76	WHR1	WNK1	WNK2	WNK3	WNT1	WRAP53	WRN	WRNIP1	XAB2	XIAP	XNDC1N	XPA	XPC	XRCC1	XRCC2	XRCC3	XRCC4	XRCC5	XRCC6	YAP1	YY1	ZBTB1	ZBTB38	ZBTB4	ZBTB40	ZBTB7A	ZC3H12A	ZDHHC16	ZDHHC20	ZFYVE26	ZGRF1	ZMAT3	ZMYND8	ZNF385A	ZNF432	ZNF668	ZNF830	ZRANB3	ZSWIM7
KE149_Increase_Inflammation_GO:0006954	inflammatory response	ABCF1	ABHD8	ACER3	ACKR1	ACKR2	ACOD1	ACVR1	ADAM17	ADAM8	ADCY1	ADCY8	ADGRE2	ADGRE5	ADM	ADORA1	ADORA2A	ADORA3	AFAP1L2	AGER	AGR2	AGTR1	AGTR2	AHSG	AIF1	AIM2	AIMP1	ALOX15	ALOX5	ANO6	ANXA1	AOC3	APCS	APIP	APOL2	APOL3	APP	ASS1	ATRN	AZU1	BCL6	BDKRB1	BDKRB2	BIRC2	BIRC3	BLNK	BMP2	BMP6	BMPR1B	BTK	C15orf39	C1QA	C2CD4A	C2CD4B	C3	C3AR1	C4A	C4B	C5	C5AR1	C5AR2	CAMK1D	CAMK4	CAMP	CARD18	CARD8	CASP1	CASP3	CASP4	CASP6	CASP8	CCL1	CCL11	CCL13	CCL14	CCL15	CCL16	CCL17	CCL18	CCL19	CCL2	CCL20	CCL21	CCL22	CCL23	CCL24	CCL25	CCL26	CCL27	CCL28	CCL3	CCL3L1	CCL4	CCL4L1	CCL5	CCL7	CCL8	CCR1	CCR2	CCR3	CCR4	CCR5	CCR6	CCR7	CCRL2	CD14	CD163	CD180	CD36	CD40	CD40LG	CD44	CD47	CD5L	CD6	CD68	CDO1	CEBPB	CELA1	CERS6	CFH	CHI3L1	CHIA	CHST1	CHST2	CHST4	CHUK	CLEC7A	CLU	CMKLR1	CNR2	CNTF	CRH	CRHBP	CRP	CSF1	CSF1R	CTNNBIP1	CUL3	CX3CL1	CX3CR1	CXCL1	CXCL10	CXCL11	CXCL13	CXCL2	CXCL3	CXCL5	CXCL6	CXCL8	CXCL9	CXCR2	CXCR3	CXCR4	CXCR6	CYBA	CYBB	DAB2IP	DHX9	DPEP1	DPP9	ELANE	ELF3	EPO	F11R	F12	F2	F2R	F2RL1	F3	F8	FADS2	FCER1A	FCER1G	FCGR1A	FCGR1BP	FCGR2A	FCGR2B	FCGR2C	FCGR3A	FCGR3B	FFAR2	FFAR3	FFAR4	FN1	FOLR2	FOS	FPR1	FPR2	FPR3	FUT4	FUT7	GATA3	GBP5	GGT5	GPER1	GPR32	GPR32P1	GPR33	GPR68	GRN	GSDMA	GSDMB	GSDMC	GSDMD	GSDME	GZMA	GZMB	GZMK	HAVCR2	HBA1	HBB	HCK	HDAC4	HDAC5	HDAC9	HIF1A	HK1	HLA-DRB1	HMGB1	HMGB2	HMOX1	HNRNPA0	HP	HRH1	HRH4	HSPG2	HYAL1	HYAL3	IFI16	IFI27	IFNA2	IFNG	IFNGR1	IFNGR2	IGHE	IGHG1	IKBKB	IKBKG	IL10RB	IL13	IL17A	IL17B	IL17C	IL17D	IL17F	IL17RA	IL17RC	IL17RE	IL18	IL18R1	IL18RAP	IL1A	IL1B	IL1F10	IL1R1	IL1RAP	IL1RL1	IL1RL2	IL1RN	IL20RA	IL22	IL22RA1	IL23A	IL23R	IL25	IL26	IL27	IL2RA	IL33	IL34	IL36A	IL36B	IL36G	IL36RN	IL37	IL4	IL4R	IL5	IL6	IL6R	IL9	INS	IRAK1	IRAK2	IRAK4	IRF5	IRGM	ITCH	ITGAL	ITGAM	ITGB1	ITGB2	ITIH4	JAK2	KDM4D	KDM6B	KIT	KLKB1	KLRG1	KNG1	KRT16	LACC1	LAT	LBP	LCN2	LGALS9	LIAS	LOXL3	LRP1	LTB4R	LXN	LY75	LY86	LY96	LYN	LYZ	MACIR	MAP3K20	MAP3K7	MAPK9	MAPKAPK2	MAPT	MBL2	MDK	MEFV	MEP1B	MFHAS1	MGLL	MIF	MMP25	MRGPRX1	MSMP	MTOR	MYD88	NAIP	NAMPT	NCR3	NDST1	NFAM1	NFATC3	NFATC4	NFKB1	NFKBID	NFKBIZ	NFX1	NINJ1	NKG7	NLRC4	NLRP1	NLRP10	NLRP2	NLRP3	NLRP4	NLRP6	NLRP9	NOD1	NOS2	NOX1	NOX4	NPFF	NR1H4	NR3C1	NR4A1	NRROS	ODAM	OLR1	ORM1	ORM2	PARK7	PARP4	PF4	PF4V1	PIK3CD	PIK3CG	PJA2	PLA2G2A	PLA2G2D	PLA2G2E	PLA2G4B	PLA2G4C	PLD3	PLD4	PLGRKT	PLSCR1	PNMA1	PPBP	PRDX5	PRKCQ	PRKCZ	PRKD1	PRMT2	PROK2	PSEN1	PSTPIP1	PTAFR	PTGDR	PTGER1	PTGER2	PTGER3	PTGER4	PTGFR	PTGIR	PTN	PTX3	PXK	PYCARD	PYDC2	PYDC5	RAC1	RARRES2	REG3A	REG3G	REL	RELA	RELB	RIPK1	RIPK2	RPS6KA4	RPS6KA5	S100A12	S100A8	S100A9	S1PR3	SAA1	SAA2	SAA4	SBNO1	SCG2	SCN11A	SCUBE1	SELE	SEMA7A	SERPINA1	SERPINA3	SERPINF2	SETD4	SIGIRR	SIGLEC1	SLAMF8	SLC11A1	SLC18A2	SMAD1	SMPDL3B	SNAP23	SNCA	SPINK7	STAB1	STAT3	STK39	SYK	TAB2	TAC1	TAC4	TACR1	TBK1	TBX21	TBXA2R	TFRC	TGFB1	THBS1	THEMIS2	TICAM1	TICAM2	TIRAP	TLR1	TLR10	TLR2	TLR3	TLR4	TLR5	TLR6	TLR7	TLR8	TLR9	TMIGD3	TNF	TNFAIP3	TNFAIP6	TNFRSF1A	TNFRSF1B	TNFRSF4	TNFSF4	TNIP1	TNIP2	TNIP3	TOLLIP	TRADD	TRAF2	TRAF3IP2	TRAF5	TREM2	TRIL	TRIM14	TRIM21	TRIM31	TSPAN18	TUSC2	TXNIP	TYROBP	USP14	VCAM1	VNN1	VPS54	WNK4	WNT5A	XCL1	XCL2	XCR1	ZBP1	ZC3H12A	ZEB2	ZNF580
KE1115_Increase_Reactive_oxygen_species_GO:0072593	reactive oxygen species metabolic process	ACOX1	ALOX12	APOA4	ATP7A	BNIP3	CAT	CCS	CYB5R4	CYBA	CYBB	CYGB	DRD5	DUOX1	DUOX2	DUOXA1	DUOXA2	EDN1	EPX	GBF1	GLS2	GPX1	GPX3	HBA1	HBB	IFI6	INAVA	LPO	MAOB	MB	MPO	MT3	NCF1	NCF1B	NCF1C	NCF2	NCF4	NDUFS3	NDUFS4	NNT	NOS2	NOS3	NOX1	NOX3	NOX4	NOX5	NOXA1	NOXO1	NQO1	PARK7	PDGFB	PLA2R1	PMAIP1	PRDX1	PRDX2	PRDX3	PRDX4	PRDX5	PRDX6	PREX1	PRG3	PXDN	PXDNL	RAC1	RAC2	SESN1	SESN2	SFTPD	SH3PXD2A	SH3PXD2B	SLC1A1	SOD1	SOD2	SOD3	TAFA4	TP53I3	TPO	TXN	UCP2
KE1392_Oxidative_Stress_GO:0006979	response to oxidative stress	ABCC1	ABL1	ABL2	ADAM9	ADPRS	ADRM1	AGAP3	AIF1	AIFM1	AKT1	ALAD	ALB	ALDH3B1	ANGPTL7	ANKZF1	APOA4	APOD	APOE	AQP1	AREG	ARNT	ATE1	ATF2	ATF4	ATM	ATOX1	ATP13A2	ATP7A	BAK1	BANF1	BECN1	BMAL1	BNIP3	BRF2	BTG1	BTK	C19orf12	CA3	CAMKK2	CAPN2	CASP3	CAT	CBX8	CCS	CD36	CD38	CDK1	CFL1	CHCHD2	CHRNA4	CHUK	CIAPIN1	COA8	COL1A1	CRK	CRYAB	CRYGD	CUL1	CUL3	CYB5B	CYGB	CYP1B1	DAPK1	DGKK	DHRS2	DUOX1	DUOX2	DUSP1	ECT2	EDN1	EDNRA	EEF2	EIF2S1	ENDOG	EPX	ERCC1	ERCC2	ERCC3	ERCC6	ERCC6L2	ERCC8	ERMP1	ERN1	ETFDH	ETV5	FABP1	FANCC	FBXO31	FER	FGF8	FOS	FOXO1	FOXO3	FOXO4	FXN	FYN	G6PD	GCLC	GCLM	GPR37	GPR37L1	GPX1	GPX2	GPX3	GPX4	GPX5	GPX6	GPX7	GPX8	GSR	GSS	GSTP1	HAO1	HBA1	HBB	HDAC2	HDAC6	HIF1A	HM13	HMOX1	HMOX2	HP	HSPA1A	HSPA1B	HTRA2	HYAL1	HYAL2	IL18BP	IL18RAP	IL6	IPCEF1	JAK2	KAT2B	KCMF1	KCNA5	KEAP1	KLF2	KLF4	KRT1	LCN2	LIAS	LONP1	LPO	LRRK2	MAP1LC3A	MAP2K1	MAP2K4	MAP3K5	MAPK13	MAPK7	MAPK8	MAPK9	MAPT	MB	MBL2	MDM2	MEAK7	MGAT3	MGST1	MICB	MMP14	MMP2	MMP3	MPO	MSRA	MSRB2	MSRB3	MT-CO1	MT-ND1	MT-ND3	MT-ND5	MT3	MYB	NAPRT	NCOA7	NDOR1	NET1	NFE2L2	NOS3	NPPA	NQO1	NUDT1	NUDT2	NXNL1	OGG1	OSER1	OXR1	OXSR1	PAM	PARK7	PARP1	PCNA	PDCD10	PDGFD	PDGFRA	PDK2	PDLIM1	PENK	PEX10	PEX12	PEX13	PEX14	PEX2	PEX5	PINK1	PJVK	PKD2	PLA2R1	PLEKHA1	PLK3	PNKP	PNPT1	PPARGC1A	PPEF2	PPIA	PPIF	PPP5C	PRDX1	PRDX2	PRDX3	PRDX4	PRDX5	PRDX6	PRKAA1	PRKAA2	PRKCA	PRKCD	PRKD1	PRKN	PRNP	PRR5L	PSIP1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMC1	PSMC2	PSMC3	PSMC4	PSMC5	PSMC6	PSMD1	PSMD11	PSMD12	PSMD13	PSMD14	PSMD2	PSMD3	PSMD4	PSMD6	PSMD7	PSMD8	PSME1	PSME2	PSME3	PTGS1	PTGS2	PTPRK	PTPRN	PXDN	PXDNL	PXN	PYCR1	PYCR2	PYROXD1	RAD52	RBM11	RBPMS	RBX1	RELA	RGS14	RHOB	RIPK1	RIPK3	RLIG1	RNF112	ROMO1	RPS3	S100A7	SCARA3	SCGB1A1	SELENOK	SELENOP	SELENOS	SESN2	SETX	SIN3A	SIRPA	SIRT1	SIRT2	SLC23A2	SLC25A24	SLC4A11	SNCA	SOD1	SOD2	SOD3	SP1	SRC	SRXN1	STAU1	STAU2	STK24	STK25	STK26	STX2	STX4	SUMO4	TACR1	TAT	TBC1D24	TET1	THG1L	TLDC2	TMEM161A	TNFAIP3	TOP2B	TOR1A	TP53	TPM1	TPO	TRIM25	TRIM32	TRPA1	TRPM2	TXN	TXNIP	TXNRD2	UBR4	UCN	UCP1	UCP2	UCP3	VKORC1L1	VNN1	VRK2	WNT16	XRCC1	ZC3H12A	ZNF580
KE1097_Occurrence_renal_proximal_tubular_necrosis_GO:0097300	programmed necrotic cell death	ALKBH7	ATG9A	ATG9B	BIRC2	CYLD	FADD	FAS	FASLG	IPMK	ITPK1	MLKL	NINJ1	PGAM5	PPIF	RIPK1	RIPK3	TLR3	TNF	TRPM7
KE177_Mitochondrial_dysfunction_GO:0007005	mitochondrion organization	A0ABJ7H8I7	ACAA2	ACAD9	ADCK1	AFG1L	AGK	AGTPBP1	AIFM1	AIFM2	APOO	APOOL	ATAD3A	ATAD3B	ATAD3C	ATF2	ATG3	ATP23	ATP2A1	ATP5F1D	ATP7A	ATPAF1	ATPAF2	BAK1	BAX	BBC3	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L2	BCS1L	BID	BIK	BLOC1S2	BNIP3	BNIP3L	BOK	CALM3	CAMK2A	CAV2	CCAR2	CEP89	CHCHD10	CHCHD2	CHCHD2P9	CHCHD3	CHCHD4	CHCHD6	CHCHD7	CIBAR1	CLPP	CLU	CLUH	CMC1	CNTNAP1	COA1	COA3	COA4	COA5	COA6	COA7	COA8	COX11	COX14	COX16	COX17	COX18	COX19	COX20	COX7A1	COX7A2L	CXADR	DMAC1	DMAC2	DNAJA3	DNAJC11	DNM1L	ECSIT	EDN1	EDNRA	ERBB4	FANCG	FASTKD3	FEZ1	FIS1	FMC1	FOXRED1	FUNDC1	FXN	FZD9	GABPB1	GDAP1	GGCT	GHITM	GSK3B	HIGD1A	HIGD1B	HIGD1C	HIGD2A	HIGD2B	HK2	HSD17B10	HSPA9	HSPD1	HTRA2	IFIT2	IMMT	KIF28P	LETM1	LETM2	LETMD1	LIG3	LONP1	LRRK2	LYRM2	LYRM7	MAIP1	MARCKS	MCL1	MFF	MFN1	MFN2	MICOS10	MICOS13	MIEF1	MIEF2	MIGA1	MIGA2	MOAP1	MSTO1	MT-ND1	MT-ND2	MT-ND4	MT-ND5	MT-ND6	MT-RNR2	MTCH1	MTCH2	MTFP1	MTFR1	MTFR1L	MTFR2	MTM1	MTRNR2L5	MTX1	MTX2	MTX3	MUL1	MYH14	NAIF1	NDUFA13	NDUFA6	NDUFAF1	NDUFAF2	NDUFAF3	NDUFAF4	NDUFAF5	NDUFAF6	NDUFAF7	NDUFAF8	NDUFC2	NDUFS1	NDUFS2	NDUFS3	NDUFS4	NDUFS5	NDUFS7	NDUFS8	NIPSNAP2	NME3	NOA1	NOL3	NOS3	NPTX1	NUBPL	OCIAD2	OMA1	OPA1	OXA1L	PARK7	PARL	PARP1	PET100	PET117	PHB1	PHB2	PID1	PINK1	PISD	PLD6	PLEC	PLSCR3	PMAIP1	PNPT1	PPARGC1A	PPM1K	PRDX3	PRKACA	PRKN	PTCD2	PTPMT1	PUM2	PYROXD2	RAB29	RAB32	RAB38	RAB5IF	RCC1L	RHOT1	RHOT2	ROMO1	RTL10	SAMM50	SCO1	SCO2	SDHAF1	SDHAF2	SDHAF3	SDHAF4	SFN	SIRT4	SIRT5	SLC25A33	SLC25A46	SMAD3	SMIM20	SOD2	SPATA18	SPATA19	SPG7	STARD7	STMP1	STOML2	STPG1	SUPV3L1	SURF1	TAFAZZIN	TERT	THEM4	THG1L	TIMM10	TIMM10B	TIMM13	TIMM21	TIMM22	TIMM29	TIMM50	TIMM8A	TIMM8B	TIMM9	TIMMDC1	TMEM11	TMEM126A	TMEM126B	TMEM186	TMEM223	TMEM242	TMEM70	TOMM20	TOMM22	TOMM40	TOMM5	TOMM6	TOMM7	TOMM70	TRABD	TRMT10B	TTC19	UCP2	UQCC1	UQCC2	UQCC3	UQCC4	UQCC5	UQCC6	UQCRFS1	USP30	VDAC2	VPS13C	VPS13D	VPS35	VPS54	WASF1	WDR81	YME1L1
KE57_Proliferation_Cell_proliferation_in_the_absence_of_cytotoxicity_GO:0051301	cell division	ABRAXAS2	ACTR8	AHCTF1	AKNA	ALKBH4	ANAPC1	ANAPC10	ANAPC11	ANAPC13	ANAPC15	ANAPC16	ANAPC2	ANAPC4	ANAPC5	ANAPC7	ANK3	ANKLE1	ANKLE2	ANKRD53	ANLN	ANXA11	APC	ARF1	ARF6	ARHGEF2	ARL3	ARL8A	ARL8B	ARPP19	ASPM	ATXN10	AURKA	AURKB	AURKC	BABAM1	BABAM2	BBS4	BCAR1	BECN1	BIN3	BIRC5	BIRC6	BOD1	BOD1L2	BORA	BRCC3	BRSK2	BUB1	BUB1B	BUB3	CABLES1	CABLES2	CCDC124	CCDC66	CCNA1	CCNA2	CCNB1	CCNB2	CCNB3	CCND1	CCND2	CCND3	CCNE1	CCNE2	CCNF	CCNG1	CCNG2	CCNK	CCNO	CCNT1	CCNT2	CCNY	CCSAP	CD2AP	CDC14A	CDC16	CDC20	CDC23	CDC25A	CDC25B	CDC25C	CDC26	CDC27	CDC6	CDC7	CDCA2	CDCA3	CDCA5	CDCA8	CDK1	CDK14	CDK2	CDK20	CDK3	CDK4	CDK5	CDK6	CDK7	CDT1	CECR2	CENPA	CENPC	CENPE	CENPF	CENPS	CENPT	CENPV	CENPW	CENPX	CEP164	CEP55	CEP63	CETN1	CETN2	CETN3	CFL1	CHEK2	CHFR	CHMP1A	CHMP1B	CHMP2A	CHMP2B	CHMP3	CHMP4A	CHMP4B	CHMP4BP1	CHMP4C	CHMP5	CHMP6	CHMP7	CIB1	CINP	CIT	CKAP2	CKAP5	CKS1B	CKS2	CLASP1	CLASP2	CLTA	CLTC	CNTRL	CNTROB	CPAP	CSNK1A1	CTDP1	CUL3	CUL7	CUZD1	DCDC1	DCLRE1A	DCT	DCTN1	DCTN3	DIS3L2	DIXDC1	DOCK7	DSN1	DYNC1H1	DYNC1LI1	DYNLT1	DYNLT3	DYRK3	E4F1	ECT2	EFHC1	EML3	EML4	ENSA	ENTR1	EPB41	EPB41L2	ERCC6L	ESPL1	ESRRB	EVI5	EXOC1	EXOC2	EXOC3	EXOC4	EXOC5	EXOC6	EXOC6B	EXOC7	EXOC8	FAM83D	FBXL7	FBXO5	FGF13	FGFR1	FGFR2	FIGN	FMN2	FSD1	FUT9	FZR1	GNAI1	GNAI2	GNAI3	GNL3	GOLGA2	GPSM2	H3-4	HAUS1	HAUS2	HAUS3	HAUS4	HAUS5	HAUS6	HAUS7	HAUS8	HELLS	HEPACAM2	HMCN1	HMGA2	HNRNPU	IER3IP1	INCENP	ING2	INO80	INSC	INTS13	IQGAP1	IQGAP2	IQGAP3	IST1	ITGB3BP	JTB	KATNA1	KATNB1	KIF11	KIF13A	KIF14	KIF18B	KIF20A	KIF20B	KIF23	KIF2A	KIF2B	KIF2C	KIF4A	KIF4B	KIFC1	KLHDC8B	KLHL13	KLHL18	KLHL21	KLHL22	KLHL42	KLHL9	KMT5A	KNL1	KNSTRN	KNTC1	LATS1	LATS2	LIG1	LIG3	LIG4	LLGL2	LMLN	LRRCC1	LUZP1	LZTS2	MAD1L1	MAD2L1	MAD2L2	MAEA	MAP10	MAP4	MAP9	MAPRE1	MAPRE2	MAPRE3	MARK4	MASTL	MAU2	MCMBP	MICAL3	MIS12	MIS18A	MIS18BP1	MISP	MITD1	MPLKIP	MTCL1	MTCL2	MTMR3	MTMR4	MYH10	MYH14	MYH9	NCAPD2	NCAPD3	NCAPG	NCAPG2	NCAPH	NDC80	NDE1	NEDD1	NEDD9	NEK1	NEK2	NEK3	NEK4	NEK6	NEK9	NOX5	NR3C1	NR5A2	NRDE2	NSL1	NSMCE2	NSUN2	NUDC	NUF2	NUMA1	NUMB	NUMBL	NUP37	NUP43	NUSAP1	OIP5	ORC4	PADI6	PAFAH1B1	PARD3	PARD3B	PARD6A	PARD6B	PARD6G	PDCD6IP	PDS5A	PDS5B	PELO	PHF13	PIK3C3	PIMREG	PKN2	PLEC	PLK1	PLK5	PMF1	POFUT3	POGZ	PPP1CA	PPP1CB	PPP1CC	PPP1R1C	PPP2R2D	PRC1	PRKCE	PRPF40A	PSRC1	PTTG1	RAB10	RAB11FIP3	RAB35	RACGAP1	RAD21	RAE1	RALA	RALB	RAN	RASA1	RBBP8	RCC1	RCC2	RECQL5	REEP3	REEP4	RGS14	RHOA	RHOB	RHOC	RNF8	ROCK1	ROCK2	ROPN1B	RPS3	RTKN	RUVBL1	SAC3D1	SAPCD2	SDE2	SEH1L	SENP5	SEPTIN1	SEPTIN10	SEPTIN11	SEPTIN12	SEPTIN14	SEPTIN2	SEPTIN3	SEPTIN4	SEPTIN5	SEPTIN6	SEPTIN7	SEPTIN8	SEPTIN9	SETDB2	SGO1	SGO2	SHCBP1L	SIRT2	SKA1	SKA2	SKA3	SMC1A	SMC2	SMC3	SMC4	SMC5	SNX18	SNX33	SNX9	SON	SOX5	SPAG5	SPART	SPAST	SPATA22	SPC24	SPC25	SPDL1	SPECC1L	SPICE1	SPIRE1	SPIRE2	SPOUT1	SPTBN1	SSNA1	STAG1	STAG2	STAMBP	STMN1	STOX1	SYCE1	SYCE2	SYCE3	SYCP1	SYCP2	SYCP3	TACC1	TACC3	TDRD12	TEAD3	TENT4B	TERF1	TEX14	TGFB2	TIMELESS	TIPIN	TNKS	TOPAZ1	TPPP	TPR	TPX2	TRIM36	TRIOBP	TSG101	TTC19	TTC28	TUBA1A	TUBA1B	TUBA1C	TUBB	TXNL4A	UBE2C	UBE2I	UBE2S	UNC119	USP16	USP37	USP39	USP44	USP8	USP9X	VPS4A	VPS4B	VRK1	WAPL	WASHC5	WASL	WEE1	WWTR1	YTHDF2	ZC3HC1	ZFP36L2	ZFYVE19	ZFYVE26	ZNF16	ZNF207	ZNF830	ZNRD2	ZW10	ZWILCH	ZWINT
KE142_Hyperplasia_Hyperplasia_GO:0014738	regulation of muscle hyperplasia	KLF4	NOS3
KE334_Promotion_Hepatocelluar_carcinoma_GO:2000345	regulation of hepatocyte proliferation	CEACAM1	CFLAR	FBXW7	HPN	MDK	PTN	TNF	TNFAIP3	XBP1
KE214_Bile_accumulation_Pathological_condition_GO:0015721	bile acid and bile salt transport	ABCB11	ABCC11	ABCC2	ABCC3	ABCC4	ABCD3	AKR1C1	AKR1C4	ATP8B1	CEACAM1	NCOA1	NCOA2	NR1H4	RXRA	SLC10A1	SLC10A2	SLC10A3	SLC10A4	SLC10A5	SLC10A6	SLC27A5	SLC44A1	SLC44A2	SLC44A3	SLC44A4	SLC44A5	SLC51A	SLC51B	SLC5A7	SLCO1A2	SLCO1B1	SLCO1B3	SLCO1B3-SLCO1B7	SLCO1B7	SLCO1C1	SLCO2B1	STARD5
KE55_Increase_Cell_injury_death_GO:0006915	apoptotic process	AATK	ABL1	ACAA2	ACIN1	ACVR1B	ACVR1C	ADAMTSL4	ADORA1	ADORA2A	ADRA1A	AEN	AHCYL1	AHR	AIFM1	AIFM2	AIFM3	AIMP1	AIMP2	AKAP1	AKT1	AKT2	AKTIP	ALOX15B	ANXA6	APAF1	APBB1	API5	APIP	APLP1	APP	AREL1	ARHGEF6	ARL6IP1	ARL6IP5	ASAH2	ATCAY	ATF2	ATF4	ATG3	ATG4D	ATG5	ATM	ATN1	ATP2A1	ATP2A3	AVEN	AXIN1	BABAM2	BAD	BAG1	BAG3	BAG6	BAK1	BAP1	BAX	BBC3	BCAP29	BCAP31	BCL10	BCL2	BCL2A1	BCL2L1	BCL2L10	BCL2L11	BCL2L12	BCL2L13	BCL2L14	BCL2L15	BCL2L2	BCL3	BCL7B	BCL7C	BCLAF1	BECN1	BEX2	BEX3	BFAR	BID	BIK	BIRC2	BIRC3	BIRC5	BIRC6	BIRC7	BIRC8	BLCAP	BLID	BLOC1S2	BMF	BMPR2	BMX	BNIP1	BNIP2	BNIP3	BNIP3L	BNIPL	BOK	BRAT1	BRCA1	BRMS1	BRSK2	BTK	BUB1	BUB1B	C19orf12	C1D	C1QBP	C3orf38	C6orf120	CAAP1	CADM1	CAMK2A	CAPN10	CAPN3	CARD14	CARD6	CARD8	CARD9	CASP1	CASP10	CASP2	CASP3	CASP4	CASP5	CASP6	CASP7	CASP8	CASP8AP2	CASP9	CAV1	CCAR1	CCAR2	CD14	CD2	CD24	CD27	CD38	CD47	CD5L	CD70	CDCA7	CDIP1	CDK1	CDK11A	CDK11B	CDK5	CDK5RAP3	CDKN1A	CEACAM5	CEACAM6	CEBPB	CECR2	CFLAR	CGB3	CGB7	CHAC1	CHEK1	CHEK2	CHI3L1	CHIA	CHMP3	CIAPIN1	CIB1	CIDEA	CIDEB	CIDEC	CIT	CITED1	CKAP2	CLC	CLEC7A	CLPTM1L	CLU	COA8	COL4A3	COLEC11	COMP	CRADD	CRH	CRIP1	CSNK2A1	CSNK2A2	CSRNP1	CSRNP2	CSRNP3	CTSC	CTSD	CTSH	CTSL	CUL1	CUL2	CUL3	CUL4A	CUL5	CXCR3	CXCR4	CYCS	CYFIP2	CYP1B1	DAB2	DAB2IP	DAD1	DAP	DAP3	DAPK1	DAPK2	DAPK3	DAPL1	DAXX	DCC	DDIAS	DDIT3	DDIT4	DDX3X	DDX41	DDX47	DDX5	DEDD	DEDD2	DELE1	DFFA	DFFB	DIABLO	DICER1	DIDO1	DMPK	DNAAF10	DNAJA3	DNAJC10	DNASE1	DNASE1L3	DNASE2	DNASE2B	DNM1L	DNMT3A	DOCK1	DPF1	DPF2	DPP8	DRAM1	DRAM2	DUX4	DYNLL1	DYRK2	E2F1	EAF2	EBAG9	EBF4	ECSCR	EDAR	EDNRA	EGLN3	EI24	ELK1	ELMO1	ELMO2	ELMO3	EMC4	EMP1	EMP2	EMP3	ENDOG	EP300	EPB41L3	EPHA2	EPHA7	ERBB3	ERBB4	ERCC2	ERCC3	ERN1	ERN2	ERO1A	ESPL1	EVA1A	EXOG	FADD	FAF1	FAIM	FAIM2	FAM162A	FAM32A	FAM3B	FAP	FAS	FASLG	FASTK	FASTKD2	FATE1	FBXO10	FEM1B	FGFR2	FGFR3	FHIT	FIS1	FKBP8	FNIP2	FOXL2	FOXO1	FOXO3	FXR1	FZD9	G0S2	G2E3	GABARAP	GADD45A	GADD45B	GADD45G	GAPDH	GAS2	GDF6	GGCT	GHITM	GLI3	GLRX2	GML	GPER1	GPR65	GRAMD4	GRIK2	GRK5	GSK3A	GSK3B	GSKIP	GSN	GULP1	GZMA	GZMB	GZMH	GZMM	HCAR2	HIC1	HIF3A	HINT1	HINT2	HIP1	HIP1R	HIPK1	HIPK2	HIPK3	HK2	HMOX1	HRK	HSP90AA1	HSPD1	HSPE1	HTRA2	HTT	IAPP	IER3	IFI16	IFI27	IFI27L1	IFI27L2	IFI6	IFIT2	IFNA2	IFNG	IFT57	IGFBP3	IKBKE	IKBKG	IL10	IL12A	IL13	IL13RA2	IL17A	IL19	IL1A	IL1B	IL20RA	IL20RB	IL22RA1	IL24	IL2RA	IL6	IL6R	ING4	INHBA	INPP5D	IRF1	IRF3	ITCH	ITGAV	ITGB2	ITGB3BP	ITPR1	JADE1	JAK2	JMY	JTB	KANK2	KAT5	KCNIP3	KIF1B	KLF11	KLLN	KMT2A	KREMEN1	KRT20	LALBA	LAPTM5	LCN2	LGALS1	LGALS12	LGALS13	LGALS14	LGALS16	LGALS7	LIG4	LMBR1L	LOC122513141	LONRF2	LTA	LTBR	MADD	MAGEH1	MAGI3	MAL	MAP1S	MAP2K4	MAP2K6	MAP2K7	MAP3K10	MAP3K5	MAP3K7	MAP3K9	MAPK1	MAPK14	MAPK3	MARCKS	MCL1	MCM2	MDM2	MECOM	MEF2A	MEF2C	MEF2D	MEGF10	MELK	MFN2	MIEN1	MINDY3	MKNK2	MLLT11	MOAP1	MRPL41	MRPS30	MSH6	MT-RNR2	MTCH1	MTFP1	MTOR	MTRNR2L5	MUL1	MX1	MYBBP1A	MYC	MYD88	MYDGF	MZB1	NAE1	NAIF1	NAIP	NCKAP1	NDUFA13	NEK6	NFKB1	NFKBIZ	NGF	NGFR	NISCH	NKX3-1	NLRC4	NLRP1	NLRP2	NLRP3	NME1	NME3	NME6	NOA1	NOC2L	NOD1	NODAL	NOL3	NOTCH2	NOX5	NPR2	NPTX1	NR3C1	NSG1	NTN1	NUAK2	NUDT2	OGT	OPA1	P2RX1	P2RX4	P2RX7	PACS2	PAEP	PAK1	PAK2	PAK4	PAK5	PAK6	PANO1	PARP1	PAWR	PAX3	PBLD	PCSK9	PDCD1	PDCD10	PDCD2L	PDCD4	PDCD5	PDCD6	PDCD6IP	PDCD7	PDCL3	PDE3A	PDE6B	PDK1	PDK2	PDPK1	PEA15	PEG10	PEG3	PERP	PHLDA1	PHLDA2	PHLDA3	PHLPP1	PIDD1	PIK3CA	PIM1	PIM2	PIM3	PKN2	PLAGL1	PLEKHF1	PLEKHO2	PLK3	PLSCR1	PLSCR2	PLSCR3	PMAIP1	PML	PMP22	POU4F1	POU4F2	PPARD	PPIA	PPID	PPIF	PPM1F	PPM1K	PPP1R13B	PPP1R13L	PPP1R15A	PPP2R1B	PPP2R2B	PRAME	PRELID1	PRF1	PRICKLE1	PRKCA	PRKCB	PRKCD	PRKCE	PRKD1	PRKDC	PRKN	PRODH	PRUNE2	PSEN1	PSMA1	PSMA2	PSMA3	PSMA4	PSMA5	PSMA6	PSMA7	PSMB1	PSMB2	PSMB3	PSMB4	PSMB5	PSMB6	PSMB7	PSMD10	PSME3	PTEN	PTGIS	PTH	PTK2B	PTPMT1	PTPRH	PTRH2	PUF60	PYCARD	QRICH1	RABEP1	RACK1	RAD21	RAF1	RALB	RASSF5	RASSF6	RASSF7	RB1	RBM5	RELT	RFFL	RFK	RHBDD1	RHOB	RHOT1	RHOT2	RIPK1	RIPK2	RIPK3	RMDN3	RNF130	RNF144B	RNF152	RNF183	RNF186	RNF216	RNF34	RNF41	ROBO2	ROCK1	RPS27L	RPS3	RPS6KB1	RRAGA	RRAGC	RRP1B	RRP8	RTKN	RTL10	RTN3	RTN4	RYBP	RYR2	S100A14	S100A8	S100A9	SAV1	SCN2A	SCRIB	SELENOK	SEMA6A	SEPTIN4	SFN	SFRP5	SGK1	SGMS1	SGPL1	SH3GLB1	SH3KBP1	SHB	SHF	SHH	SHISA5	SIAH1	SIAH2	SIK1	SIRT1	SIVA1	SIX1	SIX3	SLC1A1	SLC25A6	SLC5A11	SLC5A8	SLC75A1	SLFN12	SLIT2	SLIT3	SLK	SLTM	SMAD3	SMAD4	SMNDC1	SNW1	SOD2	SORT1	SPI1	SPIN2B	SQSTM1	SRA1	SRGN	SST	SSTR3	ST20	STEAP3	STK11	STK17A	STK17B	STK24	STK25	STK26	STK3	STK4	STPG1	SUDS3	SULF1	SYK	TAF6	TAOK1	TAOK2	TAX1BP1	TBX1	TBX2	TCHP	TCIM	TCTN3	TFPT	TGFB1	TGFB2	TGFBR1	TGFBR2	THBS1	THEM4	THOC1	THOC6	TIA1	TIAL1	TICAM1	TIGAR	TIMM50	TLR2	TLR3	TM2D1	TMBIM4	TMBIM6	TMEM102	TMEM109	TMEM117	TMEM14A	TMEM214	TMEM219	TMEM238L	TNF	TNFAIP1	TNFAIP3	TNFAIP8	TNFRSF10A	TNFRSF10B	TNFRSF10C	TNFRSF10D	TNFRSF11B	TNFRSF12A	TNFRSF18	TNFRSF19	TNFRSF1A	TNFRSF1B	TNFRSF21	TNFRSF25	TNFRSF6B	TNFRSF9	TNFSF10	TNFSF12	TNFSF14	TNIP2	TOP2A	TOPORS	TOX3	TP53	TP53AIP1	TP53BP2	TP53I3	TP53INP1	TP63	TP73	TPT1P8	TPX2	TRADD	TRAF1	TRAF2	TRAF3	TRAF4	TRAF5	TRAF7	TRAIP	TRIAP1	TRIB3	TRIM35	TRIM39	TRIM69	TRPC5	TSC2	TUBA1A	UACA	UBE2D3	UBE2Z	UBE4B	UNC5A	UNC5B	UNC5C	UNC5D	URI1	USP17L1	USP17L2	USP17L24	USP17L3	USP17L5	USP28	UXT	VDAC1	VDAC2	VIL1	VPS35	VPS54	WWOX	XAF1	XBP1	XIAP	XKR4	XKR6	XKR7	XKR8	XKR9	YARS1	ZBP1	ZBTB16	ZC3H12A	ZC3H8	ZDHHC16	ZDHHC3	ZFAND6	ZMAT3	ZNF212	ZNF385A	ZNF385B	ZNF443	ZNF622	ZPR1	ZSWIM2